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The map label for this gene is visC [H]

Identifier: 126207817

GI number: 126207817

Start: 369238

End: 370383

Strand: Reverse

Name: visC [H]

Synonym: APL_0333

Alternate gene names: 126207817

Gene position: 370383-369238 (Counterclockwise)

Preceding gene: 126207818

Following gene: 126207816

Centisome position: 16.28

GC content: 43.54

Gene sequence:

>1146_bases
ATGGTCGGTCTGGCATTAGCGGCACTCCTAAAAAATACCGATAGTCAAATTAAGATTATTGAAAAGCAAATCCCGCAAAC
CTCGGAAACTTTTTCGAATCGAGTCAGTGCGATTAACGCAACCAGTGAAAAAATGCTTGAGCAAGTCGGTGCATTGCAGC
TTATTCAAACCGAGCGTTTATCGCCTTATCAAAAAATGTCGGTATGGGAACAAGACAGTTTTGCTCACATTGAGTTTGAT
AATAGCGATCCGAGTATTCGGCAACTCGGTTTATCTCAGCTGGGATTTATTATTGAAAATAATCAAATTCAATCGGCACT
ATGGCAACAAGTAAGCCGACAAGATAATGTAGAAATTATCTTAAGCGAGCCGAAAACCGTCGGCATCAACGAAAATGGTG
CTTTCCTGACCTTAGCGAATAATGAAATGATTTCCGCTAAATTAGTGGTCGGGGCGGACGGTGCCAATTCTTGGCTTCGC
CGACAAATGCATATTCCGCTTGTAAGCAAAGATTACGAGCAAACCGCATTAGTATGTAATGTCAAAACCGTTGAACCTCA
TCATAATATCGCTCGCCAAATTTTCTCTCCGAAGAGCATTTTGGCATTTTTACCGTTAGCCGATGAAAATTTATGCTCTA
TCGTCTGGTCTTTACCGCCGGAAAAAGCGCAACAATTACAACATTGCGAAGTGCAACAATTTAATCGGGAGCTCACCATT
GCTTTTGACAACCGCTTAGGCTTAATCGAATTACAAAGCGAACGAGCGATTTACCCGCTTACCGCACGCTATGCGAGAGA
TTTCGCTCAACCTCGCTTTGCTTTAATCGGGGATGCGGCGCATACGATTCATCCGCTTGCCGGTTTAGGCGTGAACTTAG
GTTTTGCCGATGCGATCACCCTTGCCCAAGAGATCAAACAACATTTAACGCTCGGCCATGATATCGGCGAATATCGTCAT
TTACGTCGTTTCGAACGAATCCGTAAAACGGAAGCAATAAAATTACTGGCTGCGATGGAAGGCTTAAAACAGCTGTTTCA
GGGAAGTCACCCCGTCAAAAAACTGATACGAGGCGTAGGTTTATCCGCAACCAATCAACTACCGGTATTAAAGAAATTAT
TGATTGCTCAGGCGGTGGGTATTTGA

Upstream 100 bases:

>100_bases
TTAAATGGATTTTTACAAATTTATTTAAAAATATGACCGCTTATTATTTATAAACGATCTTTATATGAAATCAGCAGATA
TTGTGATTATTGGCGGCGGT

Downstream 100 bases:

>100_bases
CTTGTCTGTTTTTTAGTCAGATAATATTAACCGATAGATTTTTACTGAACTATCCTTTTCAGAAACAGTCTATTATCGGT
ACAATAGACTACGCCCTATA

Product: putative monooxygenase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MVGLALAALLKNTDSQIKIIEKQIPQTSETFSNRVSAINATSEKMLEQVGALQLIQTERLSPYQKMSVWEQDSFAHIEFD
NSDPSIRQLGLSQLGFIIENNQIQSALWQQVSRQDNVEIILSEPKTVGINENGAFLTLANNEMISAKLVVGADGANSWLR
RQMHIPLVSKDYEQTALVCNVKTVEPHHNIARQIFSPKSILAFLPLADENLCSIVWSLPPEKAQQLQHCEVQQFNRELTI
AFDNRLGLIELQSERAIYPLTARYARDFAQPRFALIGDAAHTIHPLAGLGVNLGFADAITLAQEIKQHLTLGHDIGEYRH
LRRFERIRKTEAIKLLAAMEGLKQLFQGSHPVKKLIRGVGLSATNQLPVLKKLLIAQAVGI

Sequences:

>Translated_381_residues
MVGLALAALLKNTDSQIKIIEKQIPQTSETFSNRVSAINATSEKMLEQVGALQLIQTERLSPYQKMSVWEQDSFAHIEFD
NSDPSIRQLGLSQLGFIIENNQIQSALWQQVSRQDNVEIILSEPKTVGINENGAFLTLANNEMISAKLVVGADGANSWLR
RQMHIPLVSKDYEQTALVCNVKTVEPHHNIARQIFSPKSILAFLPLADENLCSIVWSLPPEKAQQLQHCEVQQFNRELTI
AFDNRLGLIELQSERAIYPLTARYARDFAQPRFALIGDAAHTIHPLAGLGVNLGFADAITLAQEIKQHLTLGHDIGEYRH
LRRFERIRKTEAIKLLAAMEGLKQLFQGSHPVKKLIRGVGLSATNQLPVLKKLLIAQAVGI
>Mature_381_residues
MVGLALAALLKNTDSQIKIIEKQIPQTSETFSNRVSAINATSEKMLEQVGALQLIQTERLSPYQKMSVWEQDSFAHIEFD
NSDPSIRQLGLSQLGFIIENNQIQSALWQQVSRQDNVEIILSEPKTVGINENGAFLTLANNEMISAKLVVGADGANSWLR
RQMHIPLVSKDYEQTALVCNVKTVEPHHNIARQIFSPKSILAFLPLADENLCSIVWSLPPEKAQQLQHCEVQQFNRELTI
AFDNRLGLIELQSERAIYPLTARYARDFAQPRFALIGDAAHTIHPLAGLGVNLGFADAITLAQEIKQHLTLGHDIGEYRH
LRRFERIRKTEAIKLLAAMEGLKQLFQGSHPVKKLIRGVGLSATNQLPVLKKLLIAQAVGI

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=413, Percent_Identity=32.2033898305085, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI32967307, Length=355, Percent_Identity=31.830985915493, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1789273, Length=385, Percent_Identity=49.3506493506493, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI1786883, Length=387, Percent_Identity=33.8501291989664, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1789274, Length=367, Percent_Identity=26.4305177111717, Blast_Score=135, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI25146631, Length=389, Percent_Identity=29.305912596401, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6321694, Length=452, Percent_Identity=26.3274336283186, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI19920760, Length=429, Percent_Identity=30.5361305361305, Blast_Score=176, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 42525; Mature: 42525

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGLALAALLKNTDSQIKIIEKQIPQTSETFSNRVSAINATSEKMLEQVGALQLIQTERL
CHHHHHHHHHHCCCCCEEHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
SPYQKMSVWEQDSFAHIEFDNSDPSIRQLGLSQLGFIIENNQIQSALWQQVSRQDNVEII
CCHHHHHCCCCCCEEEEEECCCCCHHHHHCHHHHCEEEECCHHHHHHHHHHCCCCCEEEE
LSEPKTVGINENGAFLTLANNEMISAKLVVGADGANSWLRRQMHIPLVSKDYEQTALVCN
EECCCEEEECCCCCEEEEECCCEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCEEEEEE
VKTVEPHHNIARQIFSPKSILAFLPLADENLCSIVWSLPPEKAQQLQHCEVQQFNRELTI
EEEECCHHHHHHHHCCCCHHEEEECCCCCCHHHHEECCCHHHHHHHHHHHHHHCCCEEEE
AFDNRLGLIELQSERAIYPLTARYARDFAQPRFALIGDAAHTIHPLAGLGVNLGFADAIT
EECCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCHHHHHH
LAQEIKQHLTLGHDIGEYRHLRRFERIRKTEAIKLLAAMEGLKQLFQGSHPVKKLIRGVG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
LSATNQLPVLKKLLIAQAVGI
CCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVGLALAALLKNTDSQIKIIEKQIPQTSETFSNRVSAINATSEKMLEQVGALQLIQTERL
CHHHHHHHHHHCCCCCEEHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
SPYQKMSVWEQDSFAHIEFDNSDPSIRQLGLSQLGFIIENNQIQSALWQQVSRQDNVEII
CCHHHHHCCCCCCEEEEEECCCCCHHHHHCHHHHCEEEECCHHHHHHHHHHCCCCCEEEE
LSEPKTVGINENGAFLTLANNEMISAKLVVGADGANSWLRRQMHIPLVSKDYEQTALVCN
EECCCEEEECCCCCEEEEECCCEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCEEEEEE
VKTVEPHHNIARQIFSPKSILAFLPLADENLCSIVWSLPPEKAQQLQHCEVQQFNRELTI
EEEECCHHHHHHHHCCCCHHEEEECCCCCCHHHHEECCCHHHHHHHHHHHHHHCCCEEEE
AFDNRLGLIELQSERAIYPLTARYARDFAQPRFALIGDAAHTIHPLAGLGVNLGFADAIT
EECCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCHHHHHH
LAQEIKQHLTLGHDIGEYRHLRRFERIRKTEAIKLLAAMEGLKQLFQGSHPVKKLIRGVG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
LSATNQLPVLKKLLIAQAVGI
CCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]