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The map label for this gene is yheS [C]

Identifier: 126207793

GI number: 126207793

Start: 341631

End: 343547

Strand: Reverse

Name: yheS [C]

Synonym: APL_0309

Alternate gene names: 126207793

Gene position: 343547-341631 (Counterclockwise)

Preceding gene: 126207796

Following gene: 126207780

Centisome position: 15.1

GC content: 43.56

Gene sequence:

>1917_bases
ATGATTTTTTTCACTGATCTTATCTTAAAACGTGGACAATCCGTCCTTTTAGAAAATACCTCCGCTACCATTCATACCGG
GCAAAAAGTTGGGCTGGTCGGCAAAAACGGTTGTGGTAAATCTTCACTTTTCGCTTTAGTGAAAGGTGAATTACAACCGG
AAGGCGGCGATGTTTCTCTGCCGAAAAACTGGGCGATTTCTTGGGTAAATCAAGAAACGCCTGCACTGGAAATTTCCGCA
TTGGATTATGTGATTCAAGGCGATCGCGAATATACCGGTTTGATGAACCAGCTGGAAAAAGCCAATCAAGAAAACAACGG
CAACCAAATTGCGATGATTCATACTCAACTGGATACGATAGACGCATGGACGATTCAAGCCCGTGCAGCAACTTTATTAA
ACGGCTTGGGCTTCTCTAACGAACAACTTTCTTTACCGATGAAATCGTTCTCGGGTGGTTGGCGTATGCGTTTAAATTTA
GCGCAAGCGCTGATCTGCCGTTCTGATTTATTACTCCTCGATGAACCGACTAACCATTTGGATTTAGATGCGGTAATTTG
GTTGGAGAAATGGCTGACCAATTATCGTGGCACGCTATTATTAATCTCCCATGACCGAGATTTTCTTGATCCGATTATTG
ATCGTGTGATTCATATCGAAAATCAGCAGCTGAATGATTACACCGGTAACTACACCTCGTTTGAAATTCAGCGTGCCACC
AAAATCTCGCAACAAAATGCCGCTTATGCACAACAACAGCGCAAAGTTGCTCATTTACAGAGCTTTATCGACCGTTTTAA
AGCCAAAGCAACCAAAGCGAAACAAGCACAAAGCCGTATCAAAGCGTTGGAAAAAATGGAACTGATTGCACCGGCTTATG
CGGATAGCCCGTTTGAATTTGAATTCCGTCCGCCGCTCGCTTTGCCAAGCCCGTTATTAATGATGGAAAAAGCCGGTGCA
GGTTATGGTAACAAAACCATTTTGGAATCGGTTAAGTTGAATTTAGTCCCCGGCTCACGTATCGGTTTACTCGGGCGAAA
CGGTGCGGGTAAATCCACGCTGATTAAATTACTCGCCGGCGAATTAGCTCCGCAAACAGGGCATATTCAATTAGCTAAGG
GAGTGCAATTAGGTTATTTCGCTCAACATCAAGTAGATACGTTACGCTTTGATGAAAGCCCGTTATGGCATTTACAAAAA
ATTGCGCCGGAATTAACGGAACAAGAAGTACGCAATTATTTAGGCGGCTTTGATTTTAAAGGCGATAAAGTGAAACAAAA
CGTCGGCTCGTTTTCCGGCGGGGAAAAAGCCCGTTTAGTGTTAGCGTTAATCGTATGGCAACGTCCAAATTTACTGTTAT
TGGACGAACCGACCAACCATTTAGATTTAGAAATGCGTCAGGCACTCACCGATGCGCTCACTTACTATGAAGGCTCGCTA
GTAGTGGTTTCGCATGATCGTCATTTATTACGTAGTACGGTGAATGAATTTTATCTGGTGCATGATAAAAAAGTGGAAGA
ATTCAAAGGCGATCTGGATGATTACCAAAAATGGCTAAACGAACAAAATGCGCTGGAAGCTGCAAAAAATTCAGGAAATT
CGACCGCTTGTACGGAAGAAAAAGCGGATAACAGTGCGGCAAATCGTAAGGAGCAGAAGCGTTTAGAGGCAGAGTTACGG
CAACAAACCGCACCGTTACGTAAAAAGATCACCCAGCTAGAGAAAGATCTTGAAAAAGCGAGTGAAAAGCTAAATCAACT
CGAAGCACTACTGGCGTCAAGCGAGATCTATGAAGCGGAAAATAAAGCGCAACTAACCGAAACGCTCGCGAAGCAAATCG
AAGAGAAAAAAGCAGTTGAAGAAATCGAAATGGAATGGCTGGATTGCCAAGAACAGCTTGAGGCATTGCTCAGCTAA

Upstream 100 bases:

>100_bases
AGATCTCTTTTGCAATCAAAATCGCAAAACTCACAAACGGTATAAAATAAGGTAAAATAACCGAATTTTGTAAACTTCTC
ATCAAAACAGACCGCTTATA

Downstream 100 bases:

>100_bases
TTCTGCTTCCTTGGCGTATTTCCGAAATCCTAGCACGATCCGTACTAGGTTAAGCAGAATGCAGCCCTGCTAGGGTTGGA
AATTCCAAATAACAAGCGGT

Product: putative ABC transporter ATP-binding protein YheS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MIFFTDLILKRGQSVLLENTSATIHTGQKVGLVGKNGCGKSSLFALVKGELQPEGGDVSLPKNWAISWVNQETPALEISA
LDYVIQGDREYTGLMNQLEKANQENNGNQIAMIHTQLDTIDAWTIQARAATLLNGLGFSNEQLSLPMKSFSGGWRMRLNL
AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLTNYRGTLLLISHDRDFLDPIIDRVIHIENQQLNDYTGNYTSFEIQRAT
KISQQNAAYAQQQRKVAHLQSFIDRFKAKATKAKQAQSRIKALEKMELIAPAYADSPFEFEFRPPLALPSPLLMMEKAGA
GYGNKTILESVKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPQTGHIQLAKGVQLGYFAQHQVDTLRFDESPLWHLQK
IAPELTEQEVRNYLGGFDFKGDKVKQNVGSFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLEMRQALTDALTYYEGSL
VVVSHDRHLLRSTVNEFYLVHDKKVEEFKGDLDDYQKWLNEQNALEAAKNSGNSTACTEEKADNSAANRKEQKRLEAELR
QQTAPLRKKITQLEKDLEKASEKLNQLEALLASSEIYEAENKAQLTETLAKQIEEKKAVEEIEMEWLDCQEQLEALLS

Sequences:

>Translated_638_residues
MIFFTDLILKRGQSVLLENTSATIHTGQKVGLVGKNGCGKSSLFALVKGELQPEGGDVSLPKNWAISWVNQETPALEISA
LDYVIQGDREYTGLMNQLEKANQENNGNQIAMIHTQLDTIDAWTIQARAATLLNGLGFSNEQLSLPMKSFSGGWRMRLNL
AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLTNYRGTLLLISHDRDFLDPIIDRVIHIENQQLNDYTGNYTSFEIQRAT
KISQQNAAYAQQQRKVAHLQSFIDRFKAKATKAKQAQSRIKALEKMELIAPAYADSPFEFEFRPPLALPSPLLMMEKAGA
GYGNKTILESVKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPQTGHIQLAKGVQLGYFAQHQVDTLRFDESPLWHLQK
IAPELTEQEVRNYLGGFDFKGDKVKQNVGSFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLEMRQALTDALTYYEGSL
VVVSHDRHLLRSTVNEFYLVHDKKVEEFKGDLDDYQKWLNEQNALEAAKNSGNSTACTEEKADNSAANRKEQKRLEAELR
QQTAPLRKKITQLEKDLEKASEKLNQLEALLASSEIYEAENKAQLTETLAKQIEEKKAVEEIEMEWLDCQEQLEALLS
>Mature_638_residues
MIFFTDLILKRGQSVLLENTSATIHTGQKVGLVGKNGCGKSSLFALVKGELQPEGGDVSLPKNWAISWVNQETPALEISA
LDYVIQGDREYTGLMNQLEKANQENNGNQIAMIHTQLDTIDAWTIQARAATLLNGLGFSNEQLSLPMKSFSGGWRMRLNL
AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLTNYRGTLLLISHDRDFLDPIIDRVIHIENQQLNDYTGNYTSFEIQRAT
KISQQNAAYAQQQRKVAHLQSFIDRFKAKATKAKQAQSRIKALEKMELIAPAYADSPFEFEFRPPLALPSPLLMMEKAGA
GYGNKTILESVKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPQTGHIQLAKGVQLGYFAQHQVDTLRFDESPLWHLQK
IAPELTEQEVRNYLGGFDFKGDKVKQNVGSFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLEMRQALTDALTYYEGSL
VVVSHDRHLLRSTVNEFYLVHDKKVEEFKGDLDDYQKWLNEQNALEAAKNSGNSTACTEEKADNSAANRKEQKRLEAELR
QQTAPLRKKITQLEKDLEKASEKLNQLEALLASSEIYEAENKAQLTETLAKQIEEKKAVEEIEMEWLDCQEQLEALLS

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=521, Percent_Identity=35.8925143953935, Blast_Score=337, Evalue=3e-92,
Organism=Homo sapiens, GI27881506, Length=515, Percent_Identity=35.7281553398058, Blast_Score=323, Evalue=3e-88,
Organism=Homo sapiens, GI10947137, Length=515, Percent_Identity=35.7281553398058, Blast_Score=323, Evalue=4e-88,
Organism=Homo sapiens, GI10947135, Length=525, Percent_Identity=34.6666666666667, Blast_Score=265, Evalue=8e-71,
Organism=Homo sapiens, GI69354671, Length=525, Percent_Identity=34.6666666666667, Blast_Score=265, Evalue=1e-70,
Organism=Escherichia coli, GI1789751, Length=637, Percent_Identity=66.7189952904239, Blast_Score=886, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=524, Percent_Identity=34.5419847328244, Blast_Score=319, Evalue=3e-88,
Organism=Escherichia coli, GI1787182, Length=637, Percent_Identity=28.2574568288854, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI2367384, Length=526, Percent_Identity=30.4182509505703, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1788165, Length=198, Percent_Identity=32.3232323232323, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87081791, Length=195, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787164, Length=214, Percent_Identity=26.6355140186916, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI48994997, Length=226, Percent_Identity=25.6637168141593, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788002, Length=193, Percent_Identity=33.6787564766839, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1787758, Length=200, Percent_Identity=26.5, Blast_Score=63, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=530, Percent_Identity=36.9811320754717, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17555318, Length=517, Percent_Identity=34.0425531914894, Blast_Score=313, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI17559834, Length=531, Percent_Identity=32.5800376647834, Blast_Score=296, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI17556528, Length=299, Percent_Identity=24.0802675585284, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321121, Length=543, Percent_Identity=34.9907918968692, Blast_Score=329, Evalue=7e-91,
Organism=Saccharomyces cerevisiae, GI6320874, Length=516, Percent_Identity=34.6899224806202, Blast_Score=317, Evalue=5e-87,
Organism=Saccharomyces cerevisiae, GI6325030, Length=384, Percent_Identity=31.5104166666667, Blast_Score=161, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6323278, Length=400, Percent_Identity=28.25, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324314, Length=407, Percent_Identity=28.7469287469287, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24666836, Length=517, Percent_Identity=38.4912959381045, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24642252, Length=528, Percent_Identity=36.9318181818182, Blast_Score=346, Evalue=3e-95,
Organism=Drosophila melanogaster, GI18859989, Length=528, Percent_Identity=36.9318181818182, Blast_Score=346, Evalue=3e-95,
Organism=Drosophila melanogaster, GI24641342, Length=523, Percent_Identity=34.0344168260038, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI221500365, Length=159, Percent_Identity=35.2201257861635, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007184, Length=159, Percent_Identity=35.2201257861635, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71690; Mature: 71690

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFFTDLILKRGQSVLLENTSATIHTGQKVGLVGKNGCGKSSLFALVKGELQPEGGDVSL
CEEEHHHHHHCCCEEEEECCCCEEECCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCC
PKNWAISWVNQETPALEISALDYVIQGDREYTGLMNQLEKANQENNGNQIAMIHTQLDTI
CCCCEEEEECCCCCCEEEEHHHHEEECCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
DAWTIQARAATLLNGLGFSNEQLSLPMKSFSGGWRMRLNLAQALICRSDLLLLDEPTNHL
CCEEHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLEKWLTNYRGTLLLISHDRDFLDPIIDRVIHIENQQLNDYTGNYTSFEIQRAT
CHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHEECCCCCCCCCCCCCEEEEEHHHH
KISQQNAAYAQQQRKVAHLQSFIDRFKAKATKAKQAQSRIKALEKMELIAPAYADSPFEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
EFRPPLALPSPLLMMEKAGAGYGNKTILESVKLNLVPGSRIGLLGRNGAGKSTLIKLLAG
ECCCCCCCCCCHHHHHHCCCCCCCHHHHHHHEEEECCCCCEEEEECCCCCHHHHHHHHHH
ELAPQTGHIQLAKGVQLGYFAQHQVDTLRFDESPLWHLQKIAPELTEQEVRNYLGGFDFK
HHCCCCCCEEEECCCEECEEHHHCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
GDKVKQNVGSFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLEMRQALTDALTYYEGSL
CHHHHHHHCCCCCCCHHHEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCE
VVVSHDRHLLRSTVNEFYLVHDKKVEEFKGDLDDYQKWLNEQNALEAAKNSGNSTACTEE
EEEECCHHHHHHHHHHEEEEECCHHHHHCCCHHHHHHHHCHHHHHHHHHCCCCCCCCCCH
KADNSAANRKEQKRLEAELRQQTAPLRKKITQLEKDLEKASEKLNQLEALLASSEIYEAE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKAQLTETLAKQIEEKKAVEEIEMEWLDCQEQLEALLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIFFTDLILKRGQSVLLENTSATIHTGQKVGLVGKNGCGKSSLFALVKGELQPEGGDVSL
CEEEHHHHHHCCCEEEEECCCCEEECCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCC
PKNWAISWVNQETPALEISALDYVIQGDREYTGLMNQLEKANQENNGNQIAMIHTQLDTI
CCCCEEEEECCCCCCEEEEHHHHEEECCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
DAWTIQARAATLLNGLGFSNEQLSLPMKSFSGGWRMRLNLAQALICRSDLLLLDEPTNHL
CCEEHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLEKWLTNYRGTLLLISHDRDFLDPIIDRVIHIENQQLNDYTGNYTSFEIQRAT
CHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHEECCCCCCCCCCCCCEEEEEHHHH
KISQQNAAYAQQQRKVAHLQSFIDRFKAKATKAKQAQSRIKALEKMELIAPAYADSPFEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
EFRPPLALPSPLLMMEKAGAGYGNKTILESVKLNLVPGSRIGLLGRNGAGKSTLIKLLAG
ECCCCCCCCCCHHHHHHCCCCCCCHHHHHHHEEEECCCCCEEEEECCCCCHHHHHHHHHH
ELAPQTGHIQLAKGVQLGYFAQHQVDTLRFDESPLWHLQKIAPELTEQEVRNYLGGFDFK
HHCCCCCCEEEECCCEECEEHHHCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
GDKVKQNVGSFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLEMRQALTDALTYYEGSL
CHHHHHHHCCCCCCCHHHEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCE
VVVSHDRHLLRSTVNEFYLVHDKKVEEFKGDLDDYQKWLNEQNALEAAKNSGNSTACTEE
EEEECCHHHHHHHHHHEEEEECCHHHHHCCCHHHHHHHHCHHHHHHHHHCCCCCCCCCCH
KADNSAANRKEQKRLEAELRQQTAPLRKKITQLEKDLEKASEKLNQLEALLASSEIYEAE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKAQLTETLAKQIEEKKAVEEIEMEWLDCQEQLEALLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]