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The map label for this gene is ubiG

Identifier: 126207773

GI number: 126207773

Start: 314720

End: 315424

Strand: Reverse

Name: ubiG

Synonym: APL_0285

Alternate gene names: 126207773

Gene position: 315424-314720 (Counterclockwise)

Preceding gene: 126207780

Following gene: 126207767

Centisome position: 13.87

GC content: 40.99

Gene sequence:

>705_bases
ATGAATAATATTGATCAAACAGAGCTCGATAAATTTGAAAAAATGGCAGCCACTTGGTGGGATCCGAACGGCAGTTTTAA
ACCGATTCACTTACTTAATCCGTTACGCCTTGATTACATTCAGCAAAAAGCAAACGGCTTATTCGGCAAAAAAGTCTTGG
ATGTCGGCTGCGGCGGTGGCATTTTAAGTGAAGCGATGGCAAGAGCCGGAGCAACGGTCACCGGTATTGATATGACCACC
GAACCGCTTGAAGTTGCAAGAAAACATGCAGAAGAAAACGGTTTAAGCATTGATTACCGCCAAACAACGATTGAAGATTT
TGTGCAAAATCAGACCGCTTGTCATGCCGAAAAATTCGATGTGATTACCTGTATGGAAATGTTGGAACACGTACCGGATC
CGCTTTCGATTATTCAAAGCTGCAAGGCGTTACTCAAACCGGATGGAGTGCTGTTTTTCTCCACCATTAACCGTACGCTT
AAAGCTTATATGTTAGTTATTATCGGGGCGGAATACGTGCTAAAAATGTTGCCGAAAGGCACGCACGAATTTGAAAAATT
TATTAAACCGGCAGAATTATTAAATTGGTGCGATATGGCGGATTTACGTTGCCAAGAAATGAAAGGCTACCATTTTAATC
CTGTTACGGAAAAATTTTGGCTGAATAATGATGTAAGTTGCAATTATATTGCAATGCTCAAATAG

Upstream 100 bases:

>100_bases
GTTGAAAGTTGGATTTTGAAAGTTGAAAATGAACACAAGCGGTTAAATTAAGAGAATATTTTGCAATTTGACCTTTTTCA
CTTACTTAAGACAATTTTCT

Downstream 100 bases:

>100_bases
CTTAGAAAACAAGCGGTTATTTTTGCCTAAAATCTTACAAAAACAACCGCTTGTATTTAATCTAATTTTGCAATGCCTAA
ATGTGCATAAGTTCGGCTAG

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNNIDQTELDKFEKMAATWWDPNGSFKPIHLLNPLRLDYIQQKANGLFGKKVLDVGCGGGILSEAMARAGATVTGIDMTT
EPLEVARKHAEENGLSIDYRQTTIEDFVQNQTACHAEKFDVITCMEMLEHVPDPLSIIQSCKALLKPDGVLFFSTINRTL
KAYMLVIIGAEYVLKMLPKGTHEFEKFIKPAELLNWCDMADLRCQEMKGYHFNPVTEKFWLNNDVSCNYIAMLK

Sequences:

>Translated_234_residues
MNNIDQTELDKFEKMAATWWDPNGSFKPIHLLNPLRLDYIQQKANGLFGKKVLDVGCGGGILSEAMARAGATVTGIDMTT
EPLEVARKHAEENGLSIDYRQTTIEDFVQNQTACHAEKFDVITCMEMLEHVPDPLSIIQSCKALLKPDGVLFFSTINRTL
KAYMLVIIGAEYVLKMLPKGTHEFEKFIKPAELLNWCDMADLRCQEMKGYHFNPVTEKFWLNNDVSCNYIAMLK
>Mature_234_residues
MNNIDQTELDKFEKMAATWWDPNGSFKPIHLLNPLRLDYIQQKANGLFGKKVLDVGCGGGILSEAMARAGATVTGIDMTT
EPLEVARKHAEENGLSIDYRQTTIEDFVQNQTACHAEKFDVITCMEMLEHVPDPLSIIQSCKALLKPDGVLFFSTINRTL
KAYMLVIIGAEYVLKMLPKGTHEFEKFIKPAELLNWCDMADLRCQEMKGYHFNPVTEKFWLNNDVSCNYIAMLK

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=243, Percent_Identity=35.8024691358025, Blast_Score=163, Evalue=1e-40,
Organism=Escherichia coli, GI1788564, Length=229, Percent_Identity=56.3318777292576, Blast_Score=294, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI115533050, Length=239, Percent_Identity=35.9832635983264, Blast_Score=143, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6324476, Length=272, Percent_Identity=34.1911764705882, Blast_Score=145, Evalue=7e-36,
Organism=Drosophila melanogaster, GI281365311, Length=248, Percent_Identity=29.4354838709677, Blast_Score=140, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24585589, Length=243, Percent_Identity=29.6296296296296, Blast_Score=136, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_ACTP2 (A3MZ07)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001052998.1
- ProteinModelPortal:   A3MZ07
- STRING:   A3MZ07
- GeneID:   4850312
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0285
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- PhylomeDB:   A3MZ07
- ProtClustDB:   PRK05134
- BioCyc:   APLE416269:APL_0285-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 26514; Mature: 26514

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIDQTELDKFEKMAATWWDPNGSFKPIHLLNPLRLDYIQQKANGLFGKKVLDVGCGGG
CCCCCHHHHHHHHHHHHHEECCCCCCCCEECCCHHHHHHHHHHHCCCHHHHHHHCCCCCH
ILSEAMARAGATVTGIDMTTEPLEVARKHAEENGLSIDYRQTTIEDFVQNQTACHAEKFD
HHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCHHHHHHHHHH
VITCMEMLEHVPDPLSIIQSCKALLKPDGVLFFSTINRTLKAYMLVIIGAEYVLKMLPKG
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
THEFEKFIKPAELLNWCDMADLRCQEMKGYHFNPVTEKFWLNNDVSCNYIAMLK
HHHHHHHCCHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCEEEEEC
>Mature Secondary Structure
MNNIDQTELDKFEKMAATWWDPNGSFKPIHLLNPLRLDYIQQKANGLFGKKVLDVGCGGG
CCCCCHHHHHHHHHHHHHEECCCCCCCCEECCCHHHHHHHHHHHCCCHHHHHHHCCCCCH
ILSEAMARAGATVTGIDMTTEPLEVARKHAEENGLSIDYRQTTIEDFVQNQTACHAEKFD
HHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCHHHHHHHHHH
VITCMEMLEHVPDPLSIIQSCKALLKPDGVLFFSTINRTLKAYMLVIIGAEYVLKMLPKG
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
THEFEKFIKPAELLNWCDMADLRCQEMKGYHFNPVTEKFWLNNDVSCNYIAMLK
HHHHHHHCCHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA