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The map label for this gene is tbpA [H]

Identifier: 126207734

GI number: 126207734

Start: 264910

End: 267177

Strand: Direct

Name: tbpA [H]

Synonym: APL_0246

Alternate gene names: 126207734

Gene position: 264910-267177 (Clockwise)

Preceding gene: 126207733

Following gene: 126207739

Centisome position: 11.65

GC content: 40.3

Gene sequence:

>2268_bases
GTGAAGCAATTTAAATTAAGTTTAAGTTATATCGCAATCCAATCCGCTTTCCTGATTTTATCCGCACAAACTTATGCGAA
GCAAAATGAAACGGAATTAGATACCGTTACAGTCAAAGCAAAAACGGAGATACACCGCCGACAAAACGAAGTAACAGGTT
TGGGTAAAGTGACTAAAATCAGTAAAGATCTTGATAAAGAGCAGGTACAAAATATTCGTGATCTGACCCGTTATGATCCC
GGTATTTCGGTAGTTGAGCAAGGAAGAGGCGCAAGTAGCGGCTATTCGATTCGCGGGGTAGATCGCAATCGTGTGGCATT
ACTAGTAGACGGGCTACCGCAAATTCAGTCCTATAAAAGTCTTTCTCTGTTTGCACAAAGCGGAGCAATTAATGAAATCG
AATATGAAAATATTCGTTCGATTGAATTTAGTAAAGGAGCCAGTTCACAAGAATACGGTAGCGGTGCCTTAGGCGGTGCC
GTCGGCTTCCGTACTAAAAATCCCGACGATGTGATTAAAGAAGGACAAAATTGGGGATTAGACAGTAAAACTGCGTATTC
GAGTAAAAATAAGCAATTTAGCGAATCGCTTAGTTTTGCAGGTCGTTCCGGCGGATTTGAAGCATTGGTGCAATATACGC
ATCGAAAGGGCAAAGAAACGGAAATTCATAAAGATGCGACTAAGGTAAGGCAGTCCTTCTACCGTCTCGTGCCAAGAGAA
CTTAATTGGGATAAAAATCAAAGAGATAACTGGTTTGTCTTTGAAGACGAATGCCCGACCGGGCAAGGAAGTAATCCCGG
CTGTGTTCCGCGTCCGATTGTACGAGGGGCGAAAGTGATAAAAGATTCGACTAATGCGAAAGATTACACAGGAGACGGGC
GTATTGCACCGAATCCTATGAAATATCAGTCGGGGTCTTGGTTATTTAAATTAGCCTACCATTTCTCACCGCAACATTCG
GTAAACGCCGTATTTGAACAAACTAAGCAACGCTATGATATACAGGATATGGCACAAGCCAAATATTCAAATTTATTACC
GAATAATAAAGGAGAGCCGGATCGTAAAAAAACCGAAGTGGAATATTCGCTATTCGGTAGAAATTTCTATCCGGATGATC
CTTCTCAAGCAATAGGTTATGGAAATACGCTTAATCCTAGTTTAGTGCGAAGTGCTTATTGGAGCAGAGCGAGATTTTTT
GACGAACGGCATACGAAACGCCGCTTAGGGTTTGGTTATCAGTATAAGTCTGAAAATGATAAAGGCATTTTTGATCGTCT
AAATCTCAATTTGGATCAACAAGATATTCGATTACTGACCAAGTTACACAGCCTAAGTTGTAGTAGGTACCCATATTTCG
ATAAAAATTGTAAGATAACGCCGGATAAGCGAGATGCGAATGCTACTTATGAACGGAATATTTATAAGGAACGTCATAAA
CAAGTACAGCTTTCTTTTGAAAAGGATTTAGCAATCGGGAGAACCCAGCACTTATTTAATTTATCCATGAGTTATGATCG
TATGCGTTCCAACCATAAGCGAGATCAATTCGAACGCGTTTATTTAGTTTATTCTAAGGAAGATGAATCGGAGCATCCGT
ATTATGATGTCGGAAATCGAGATAAAGATGTCGGTTATTACAATAGCGGTACTTATAAATACCCGAGAATTATCGGTAAA
AGACAAGCAATAGTCGCTCATAATAATTATTGTAAGTTTGATATGCATTATGGAAAACGCAAAGATTTTAGCGATTGTTC
GGCACATATTACCAAAGGGCAGCATTATGCGATTGGCTTATCGGATCGTATTTTCTTCGGCGATAAGCTGGATCTAGGTT
TGGGTGTACGGTATGACTATCATCGTTTTAAATCGGATGATGATTGGGTCAATACCGGTACACACAAGAATTTCTCTTGG
AATACCGGACTGACGATTCGACCGAGAGAATATATCGCTTTATCTTACCGAGCTTCCAGCGGTTTTAGAGTACCGTCATT
TGTTGAAATGTTCGGTCGTCGAGTTCCCGGTGCCGCAGATAACAAATATTGGCGTAGAGACTTACTTAAGAAAAAATTAA
CTTCGGAAAAAGCACTTAACCAAGAAGTCGGAGTGGCGTTTAACGGCAATTTAGGAGTATTGGAAGTCAGTTATTTTGAT
AACCGTTATCGAGACTTGATTGTCAGTGCGAAAGAAAAAGGGATTGACGGAATAGCGGGTTTCTATAATCTCCAATCGAT
TAATCTTAATGGGGTACCTATTGGGTAA

Upstream 100 bases:

>100_bases
TCGGTGGTAGTTTGTTAAGTACTGAGCAAAGTCAAGATAAGGCTGCCGGTGTATTCGGTGCAAAACGTCAAGTCGAGAAG
AAATAGGGGAGAGCTAGAGA

Downstream 100 bases:

>100_bases
ACTCAATTGGCACGGTATTTGGTCGGCTTTACCAGACGGCTTATATTCAAATCTTGCTTATAACCGTATTAAAGTGAAAA
ACGTCGATACGAAGCCGAAT

Product: truncated transferrin-binding protein 1 precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 755; Mature: 755

Protein sequence:

>755_residues
MKQFKLSLSYIAIQSAFLILSAQTYAKQNETELDTVTVKAKTEIHRRQNEVTGLGKVTKISKDLDKEQVQNIRDLTRYDP
GISVVEQGRGASSGYSIRGVDRNRVALLVDGLPQIQSYKSLSLFAQSGAINEIEYENIRSIEFSKGASSQEYGSGALGGA
VGFRTKNPDDVIKEGQNWGLDSKTAYSSKNKQFSESLSFAGRSGGFEALVQYTHRKGKETEIHKDATKVRQSFYRLVPRE
LNWDKNQRDNWFVFEDECPTGQGSNPGCVPRPIVRGAKVIKDSTNAKDYTGDGRIAPNPMKYQSGSWLFKLAYHFSPQHS
VNAVFEQTKQRYDIQDMAQAKYSNLLPNNKGEPDRKKTEVEYSLFGRNFYPDDPSQAIGYGNTLNPSLVRSAYWSRARFF
DERHTKRRLGFGYQYKSENDKGIFDRLNLNLDQQDIRLLTKLHSLSCSRYPYFDKNCKITPDKRDANATYERNIYKERHK
QVQLSFEKDLAIGRTQHLFNLSMSYDRMRSNHKRDQFERVYLVYSKEDESEHPYYDVGNRDKDVGYYNSGTYKYPRIIGK
RQAIVAHNNYCKFDMHYGKRKDFSDCSAHITKGQHYAIGLSDRIFFGDKLDLGLGVRYDYHRFKSDDDWVNTGTHKNFSW
NTGLTIRPREYIALSYRASSGFRVPSFVEMFGRRVPGAADNKYWRRDLLKKKLTSEKALNQEVGVAFNGNLGVLEVSYFD
NRYRDLIVSAKEKGIDGIAGFYNLQSINLNGVPIG

Sequences:

>Translated_755_residues
MKQFKLSLSYIAIQSAFLILSAQTYAKQNETELDTVTVKAKTEIHRRQNEVTGLGKVTKISKDLDKEQVQNIRDLTRYDP
GISVVEQGRGASSGYSIRGVDRNRVALLVDGLPQIQSYKSLSLFAQSGAINEIEYENIRSIEFSKGASSQEYGSGALGGA
VGFRTKNPDDVIKEGQNWGLDSKTAYSSKNKQFSESLSFAGRSGGFEALVQYTHRKGKETEIHKDATKVRQSFYRLVPRE
LNWDKNQRDNWFVFEDECPTGQGSNPGCVPRPIVRGAKVIKDSTNAKDYTGDGRIAPNPMKYQSGSWLFKLAYHFSPQHS
VNAVFEQTKQRYDIQDMAQAKYSNLLPNNKGEPDRKKTEVEYSLFGRNFYPDDPSQAIGYGNTLNPSLVRSAYWSRARFF
DERHTKRRLGFGYQYKSENDKGIFDRLNLNLDQQDIRLLTKLHSLSCSRYPYFDKNCKITPDKRDANATYERNIYKERHK
QVQLSFEKDLAIGRTQHLFNLSMSYDRMRSNHKRDQFERVYLVYSKEDESEHPYYDVGNRDKDVGYYNSGTYKYPRIIGK
RQAIVAHNNYCKFDMHYGKRKDFSDCSAHITKGQHYAIGLSDRIFFGDKLDLGLGVRYDYHRFKSDDDWVNTGTHKNFSW
NTGLTIRPREYIALSYRASSGFRVPSFVEMFGRRVPGAADNKYWRRDLLKKKLTSEKALNQEVGVAFNGNLGVLEVSYFD
NRYRDLIVSAKEKGIDGIAGFYNLQSINLNGVPIG
>Mature_755_residues
MKQFKLSLSYIAIQSAFLILSAQTYAKQNETELDTVTVKAKTEIHRRQNEVTGLGKVTKISKDLDKEQVQNIRDLTRYDP
GISVVEQGRGASSGYSIRGVDRNRVALLVDGLPQIQSYKSLSLFAQSGAINEIEYENIRSIEFSKGASSQEYGSGALGGA
VGFRTKNPDDVIKEGQNWGLDSKTAYSSKNKQFSESLSFAGRSGGFEALVQYTHRKGKETEIHKDATKVRQSFYRLVPRE
LNWDKNQRDNWFVFEDECPTGQGSNPGCVPRPIVRGAKVIKDSTNAKDYTGDGRIAPNPMKYQSGSWLFKLAYHFSPQHS
VNAVFEQTKQRYDIQDMAQAKYSNLLPNNKGEPDRKKTEVEYSLFGRNFYPDDPSQAIGYGNTLNPSLVRSAYWSRARFF
DERHTKRRLGFGYQYKSENDKGIFDRLNLNLDQQDIRLLTKLHSLSCSRYPYFDKNCKITPDKRDANATYERNIYKERHK
QVQLSFEKDLAIGRTQHLFNLSMSYDRMRSNHKRDQFERVYLVYSKEDESEHPYYDVGNRDKDVGYYNSGTYKYPRIIGK
RQAIVAHNNYCKFDMHYGKRKDFSDCSAHITKGQHYAIGLSDRIFFGDKLDLGLGVRYDYHRFKSDDDWVNTGTHKNFSW
NTGLTIRPREYIALSYRASSGFRVPSFVEMFGRRVPGAADNKYWRRDLLKKKLTSEKALNQEVGVAFNGNLGVLEVSYFD
NRYRDLIVSAKEKGIDGIAGFYNLQSINLNGVPIG

Specific function: Acts as a transferrin receptor and is required for transferrin utilization [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=174, Percent_Identity=28.735632183908, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010949
- InterPro:   IPR010948
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 86614; Mature: 86614

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFKLSLSYIAIQSAFLILSAQTYAKQNETELDTVTVKAKTEIHRRQNEVTGLGKVTKI
CCCEEEEHHHHHHHHHHHEEEHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHHH
SKDLDKEQVQNIRDLTRYDPGISVVEQGRGASSGYSIRGVDRNRVALLVDGLPQIQSYKS
HHHCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEECCCCCCEEEEECCCHHHHHHHH
LSLFAQSGAINEIEYENIRSIEFSKGASSQEYGSGALGGAVGFRTKNPDDVIKEGQNWGL
HHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCC
DSKTAYSSKNKQFSESLSFAGRSGGFEALVQYTHRKGKETEIHKDATKVRQSFYRLVPRE
CCCHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHH
LNWDKNQRDNWFVFEDECPTGQGSNPGCVPRPIVRGAKVIKDSTNAKDYTGDGRIAPNPM
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KYQSGSWLFKLAYHFSPQHSVNAVFEQTKQRYDIQDMAQAKYSNLLPNNKGEPDRKKTEV
CCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHEE
EYSLFGRNFYPDDPSQAIGYGNTLNPSLVRSAYWSRARFFDERHTKRRLGFGYQYKSEND
EEEEECCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
KGIFDRLNLNLDQQDIRLLTKLHSLSCSRYPYFDKNCKITPDKRDANATYERNIYKERHK
CCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHH
QVQLSFEKDLAIGRTQHLFNLSMSYDRMRSNHKRDQFERVYLVYSKEDESEHPYYDVGNR
EEEEEEHHCCCCCCHHHEEEECCHHHHHHHCCCCCCEEEEEEEEECCCCCCCCEECCCCC
DKDVGYYNSGTYKYPRIIGKRQAIVAHNNYCKFDMHYGKRKDFSDCSAHITKGQHYAIGL
CCCCCEECCCCEECCHHHCCCEEEEEECCEEEEECCCCCCCCCCHHHHHHCCCCEEEEEC
SDRIFFGDKLDLGLGVRYDYHRFKSDDDWVNTGTHKNFSWNTGLTIRPREYIALSYRASS
CCEEEECCCCCCCCCCEEHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCC
GFRVPSFVEMFGRRVPGAADNKYWRRDLLKKKLTSEKALNQEVGVAFNGNLGVLEVSYFD
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHCCEEECCCEEEEEEECCC
NRYRDLIVSAKEKGIDGIAGFYNLQSINLNGVPIG
CHHHHHHHHHHHCCCCCHHHEEEEEEECCCCCCCC
>Mature Secondary Structure
MKQFKLSLSYIAIQSAFLILSAQTYAKQNETELDTVTVKAKTEIHRRQNEVTGLGKVTKI
CCCEEEEHHHHHHHHHHHEEEHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHCCCCHHHHH
SKDLDKEQVQNIRDLTRYDPGISVVEQGRGASSGYSIRGVDRNRVALLVDGLPQIQSYKS
HHHCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEECCCCCCEEEEECCCHHHHHHHH
LSLFAQSGAINEIEYENIRSIEFSKGASSQEYGSGALGGAVGFRTKNPDDVIKEGQNWGL
HHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCC
DSKTAYSSKNKQFSESLSFAGRSGGFEALVQYTHRKGKETEIHKDATKVRQSFYRLVPRE
CCCHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHH
LNWDKNQRDNWFVFEDECPTGQGSNPGCVPRPIVRGAKVIKDSTNAKDYTGDGRIAPNPM
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KYQSGSWLFKLAYHFSPQHSVNAVFEQTKQRYDIQDMAQAKYSNLLPNNKGEPDRKKTEV
CCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHEE
EYSLFGRNFYPDDPSQAIGYGNTLNPSLVRSAYWSRARFFDERHTKRRLGFGYQYKSEND
EEEEECCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
KGIFDRLNLNLDQQDIRLLTKLHSLSCSRYPYFDKNCKITPDKRDANATYERNIYKERHK
CCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHH
QVQLSFEKDLAIGRTQHLFNLSMSYDRMRSNHKRDQFERVYLVYSKEDESEHPYYDVGNR
EEEEEEHHCCCCCCHHHEEEECCHHHHHHHCCCCCCEEEEEEEEECCCCCCCCEECCCCC
DKDVGYYNSGTYKYPRIIGKRQAIVAHNNYCKFDMHYGKRKDFSDCSAHITKGQHYAIGL
CCCCCEECCCCEECCHHHCCCEEEEEECCEEEEECCCCCCCCCCHHHHHHCCCCEEEEEC
SDRIFFGDKLDLGLGVRYDYHRFKSDDDWVNTGTHKNFSWNTGLTIRPREYIALSYRASS
CCEEEECCCCCCCCCCEEHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCC
GFRVPSFVEMFGRRVPGAADNKYWRRDLLKKKLTSEKALNQEVGVAFNGNLGVLEVSYFD
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHCCEEECCCEEEEEEECCC
NRYRDLIVSAKEKGIDGIAGFYNLQSINLNGVPIG
CHHHHHHHHHHHCCCCCHHHEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]