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The map label for this gene is argD [H]

Identifier: 126207732

GI number: 126207732

Start: 261791

End: 262972

Strand: Direct

Name: argD [H]

Synonym: APL_0244

Alternate gene names: 126207732

Gene position: 261791-262972 (Clockwise)

Preceding gene: 126207731

Following gene: 126207733

Centisome position: 11.51

GC content: 43.91

Gene sequence:

>1182_bases
ATGAACAGCAACGACATCAAACAATTAGATGCGGATTATATCGCACAAACTTACGGTAGATTTAACCTCGCCCTTTCACA
CGGAAAAGGTTGTGACGTATGGGATTTTGAAGGCAATCAGTATTTAGATTTTACTAGCGGTATCGGGACAAACAGCCTTG
GCTGGGCGGATGACGGTTGGCTGGCGGCGGTAACTACGCAAGCAGGCAAATTACAGCATACTTCAAATATATTTTTTACC
GAGCCGTCTGCTGTACTGGCTAAAAGTTTGGTTGAAGCAAGCGGTCTAAAACGTGTGTTTTTTTGCAACTCGGGGGCAGA
AGCGAATGAAGGAGCGATTAAAACCGCACGTAAATATAGCCATGATAAATACGGTAAGGGCAGAGCGACCTTACTCAGTT
TAGTCAATTCATTCCACGGACGTACGATTTCAACCCTTGCCGCAACAGGACAAGATGTGTTTCATCAACATTTCTTCCCA
TTTACACAAGGTTTTGAACATACGCCGGCGAACGATTTAGATGCCTTACATGCACGTATTGAACAAGATGACGTGTGTGC
GATTATTTTAGAAATCGTACAGGGTGAGGGTGGTGTTTGTGCATTAGATACTGAATATTTACAAGGCGTACAAGCGATTT
GCCAAGCCAAAGATATCATTTTGATTATTGATGAGGTACAAACCGGTATCGGACGCACCGGAAAATTGTTTGCTTATCAG
CATTTCGGTTTACAGCCAGATATTATCACGCTTGCCAAAGGCTTAGGCGGCGGTTTACCGATCGGTGCTTTCGTATTAGG
TGGCAAATGCCAAAATACACTCGGTAAAAGCGATCACGGCTCAACCTTCGGAGCAAATCCGGTCTGTTGTGCGGCGGCGA
ATGCGGTATTAGCGAAAATAGATGAAAAATTCTTAGCGGATGTAGCGGCTAAAGGCGAAAAATTACGTGCGGCATTGCTT
ACCTTACCAAAAGTAAAATCGGTTTCCGGCTTAGGTTTAATGCTGGGTATTGAATTTGAGGATGGGGTAAAAGCCGCTGA
TGTGGTGGCGAAAGCAATAGAGAAAGGTGTATTAACACTTACTGCTAAAACCAAATTACGTTTATTACCACCGTTAGTGA
TTTCCGAACAACAAATCGATCACGGTGTCGCGGTGTTAAGAGAGGTTTTGGAAAGCCTGTAA

Upstream 100 bases:

>100_bases
GCGAATATCATTGACGGACGAGTACCGCATGCCATTTTAGTCTCATTATTCGGCGGTAAAAACGGTACGCTTTTTTATAA
AAAATAATTAGGAAGACAAT

Downstream 100 bases:

>100_bases
GCGGTTAGATTTTAGCAATTTTTTGCAAATAACGTTTAAAAAATTTAAGACGAACGAATCCCCTTAAGTGAATCACTTAG
GGGGATTTTTTTATTATGTT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MNSNDIKQLDADYIAQTYGRFNLALSHGKGCDVWDFEGNQYLDFTSGIGTNSLGWADDGWLAAVTTQAGKLQHTSNIFFT
EPSAVLAKSLVEASGLKRVFFCNSGAEANEGAIKTARKYSHDKYGKGRATLLSLVNSFHGRTISTLAATGQDVFHQHFFP
FTQGFEHTPANDLDALHARIEQDDVCAIILEIVQGEGGVCALDTEYLQGVQAICQAKDIILIIDEVQTGIGRTGKLFAYQ
HFGLQPDIITLAKGLGGGLPIGAFVLGGKCQNTLGKSDHGSTFGANPVCCAAANAVLAKIDEKFLADVAAKGEKLRAALL
TLPKVKSVSGLGLMLGIEFEDGVKAADVVAKAIEKGVLTLTAKTKLRLLPPLVISEQQIDHGVAVLREVLESL

Sequences:

>Translated_393_residues
MNSNDIKQLDADYIAQTYGRFNLALSHGKGCDVWDFEGNQYLDFTSGIGTNSLGWADDGWLAAVTTQAGKLQHTSNIFFT
EPSAVLAKSLVEASGLKRVFFCNSGAEANEGAIKTARKYSHDKYGKGRATLLSLVNSFHGRTISTLAATGQDVFHQHFFP
FTQGFEHTPANDLDALHARIEQDDVCAIILEIVQGEGGVCALDTEYLQGVQAICQAKDIILIIDEVQTGIGRTGKLFAYQ
HFGLQPDIITLAKGLGGGLPIGAFVLGGKCQNTLGKSDHGSTFGANPVCCAAANAVLAKIDEKFLADVAAKGEKLRAALL
TLPKVKSVSGLGLMLGIEFEDGVKAADVVAKAIEKGVLTLTAKTKLRLLPPLVISEQQIDHGVAVLREVLESL
>Mature_393_residues
MNSNDIKQLDADYIAQTYGRFNLALSHGKGCDVWDFEGNQYLDFTSGIGTNSLGWADDGWLAAVTTQAGKLQHTSNIFFT
EPSAVLAKSLVEASGLKRVFFCNSGAEANEGAIKTARKYSHDKYGKGRATLLSLVNSFHGRTISTLAATGQDVFHQHFFP
FTQGFEHTPANDLDALHARIEQDDVCAIILEIVQGEGGVCALDTEYLQGVQAICQAKDIILIIDEVQTGIGRTGKLFAYQ
HFGLQPDIITLAKGLGGGLPIGAFVLGGKCQNTLGKSDHGSTFGANPVCCAAANAVLAKIDEKFLADVAAKGEKLRAALL
TLPKVKSVSGLGLMLGIEFEDGVKAADVVAKAIEKGVLTLTAKTKLRLLPPLVISEQQIDHGVAVLREVLESL

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=400, Percent_Identity=33.5, Blast_Score=214, Evalue=8e-56,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=35.3333333333333, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI13994255, Length=449, Percent_Identity=28.9532293986637, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI37574042, Length=410, Percent_Identity=27.8048780487805, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI226442705, Length=410, Percent_Identity=27.5609756097561, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI226442709, Length=390, Percent_Identity=27.6923076923077, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI24119277, Length=419, Percent_Identity=24.582338902148, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI188536080, Length=431, Percent_Identity=23.2018561484919, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI38679950, Length=431, Percent_Identity=23.2018561484919, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI38679946, Length=431, Percent_Identity=23.2018561484919, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788044, Length=380, Percent_Identity=38.6842105263158, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1789759, Length=364, Percent_Identity=38.1868131868132, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI145693181, Length=378, Percent_Identity=34.3915343915344, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1789016, Length=435, Percent_Identity=32.4137931034483, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1787560, Length=425, Percent_Identity=32.9411764705882, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1786991, Length=425, Percent_Identity=28.2352941176471, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786349, Length=358, Percent_Identity=28.4916201117318, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25144271, Length=393, Percent_Identity=33.587786259542, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI25144274, Length=274, Percent_Identity=35.4014598540146, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32564660, Length=431, Percent_Identity=30.8584686774942, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=415, Percent_Identity=31.566265060241, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI71981843, Length=175, Percent_Identity=30.2857142857143, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17541228, Length=456, Percent_Identity=24.3421052631579, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=398, Percent_Identity=37.4371859296482, Blast_Score=248, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6323470, Length=419, Percent_Identity=32.9355608591885, Blast_Score=194, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6324386, Length=392, Percent_Identity=27.0408163265306, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=273, Percent_Identity=27.4725274725275, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357415, Length=388, Percent_Identity=35.5670103092784, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI161085790, Length=417, Percent_Identity=29.0167865707434, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28574759, Length=412, Percent_Identity=29.8543689320388, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21356575, Length=422, Percent_Identity=27.7251184834123, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281366494, Length=456, Percent_Identity=25.219298245614, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24667139, Length=456, Percent_Identity=25.219298245614, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24667143, Length=456, Percent_Identity=25.219298245614, Blast_Score=101, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41875; Mature: 41875

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSNDIKQLDADYIAQTYGRFNLALSHGKGCDVWDFEGNQYLDFTSGIGTNSLGWADDGW
CCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCE
LAAVTTQAGKLQHTSNIFFTEPSAVLAKSLVEASGLKRVFFCNSGAEANEGAIKTARKYS
EEEEECCCCCEEECCCEEEECCHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHC
HDKYGKGRATLLSLVNSFHGRTISTLAATGQDVFHQHFFPFTQGFEHTPANDLDALHARI
CCCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCHHCCCCCCCCCHHHHHHHHC
EQDDVCAIILEIVQGEGGVCALDTEYLQGVQAICQAKDIILIIDEVQTGIGRTGKLFAYQ
CCCHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCEEEEEE
HFGLQPDIITLAKGLGGGLPIGAFVLGGKCQNTLGKSDHGSTFGANPVCCAAANAVLAKI
CCCCCCHHHHHHHHCCCCCCHHHEEECCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
DEKFLADVAAKGEKLRAALLTLPKVKSVSGLGLMLGIEFEDGVKAADVVAKAIEKGVLTL
HHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEE
TAKTKLRLLPPLVISEQQIDHGVAVLREVLESL
EECCEEEECCCHHCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNSNDIKQLDADYIAQTYGRFNLALSHGKGCDVWDFEGNQYLDFTSGIGTNSLGWADDGW
CCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCE
LAAVTTQAGKLQHTSNIFFTEPSAVLAKSLVEASGLKRVFFCNSGAEANEGAIKTARKYS
EEEEECCCCCEEECCCEEEECCHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHC
HDKYGKGRATLLSLVNSFHGRTISTLAATGQDVFHQHFFPFTQGFEHTPANDLDALHARI
CCCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCHHCCCCCCCCCHHHHHHHHC
EQDDVCAIILEIVQGEGGVCALDTEYLQGVQAICQAKDIILIIDEVQTGIGRTGKLFAYQ
CCCHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCEEEEEE
HFGLQPDIITLAKGLGGGLPIGAFVLGGKCQNTLGKSDHGSTFGANPVCCAAANAVLAKI
CCCCCCHHHHHHHHCCCCCCHHHEEECCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
DEKFLADVAAKGEKLRAALLTLPKVKSVSGLGLMLGIEFEDGVKAADVVAKAIEKGVLTL
HHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEE
TAKTKLRLLPPLVISEQQIDHGVAVLREVLESL
EECCEEEECCCHHCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA