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The map label for this gene is ytfL [C]

Identifier: 126207716

GI number: 126207716

Start: 247952

End: 249247

Strand: Reverse

Name: ytfL [C]

Synonym: APL_0228

Alternate gene names: 126207716

Gene position: 249247-247952 (Counterclockwise)

Preceding gene: 126207717

Following gene: 126207706

Centisome position: 10.96

GC content: 41.9

Gene sequence:

>1296_bases
ATGAGCTTATTTGAAGCAAGCTTAATTATCTTATTATTAATTGTTACCAGTGCGGTAATTTCTTCGGCAGAAATCTCACT
TGCCGGCGCAAGGAAATTGAAACTGCAATCAATGATCAACGAAGGCGACCTCCGTGCCGAAAAAGTCTTAAAACTTCAAG
AGCAGCCTGGACGTTTTATTACCGTGGTGCAAATCGGCTTAAATATGGTGGCAATTCTCGGCGGTGTGGTCGGCGAAAGT
GCGATCAATCCTTACTTTAGTGAATTACTTTCCAAATATACGCAAGCGGAATGGGTTGATAGTGCCGCCTCTTGGATTGC
CTTTATCATCGTTACCTCTGCATTCGTGCTCTTTGCAGACTTAATGCCGAAGCGACTGGCAATGACCTATCCGGAAAAAA
TTGCGGTGCGCACCATCGGCGTTATGATGTTTTGTATCGCCTTATTTAAACCGCTCGTACTATTTTTCGATTGGATCGCC
AATACGTTATTTAAGTTTTTCCACGTTTCTACCGTACGCCAAGACAATATGACCTCCGAAGATATTGTTGCGGTGGTTGA
TGCGGGAGCAAAAGCCGGCATTTTAAAAGCGCAAGAACATTACTTAATTGAAAATGTGTTTGAAATGCAAGAACGTCGTG
TGACCTCAACCATGACCACGCGTGAGCATATCGTTTTTTTAAACCGCACAGACAACCGTGAAAAAGTATTGGAAACATTA
GGCGAAGATCCCTATTCCAAAGTGCTGATTTGTGATGACGGACTAGATAAAATCTTAGGTTATATCGAAACCCACGATCT
CCTGACACAGTACCTAAAAAACGATAACGTGTCGCTAACGGATGCGAAATTACTGAAAAAGTCGCTTTTTATTCCGGATA
CGCTCTCGCTGTACGAAGTTTTGGAGCTGTTTAAATCCGCCGGCGAAGATTTTGCGGTTATTGTAAACGAATATGCATTA
GTAGTGGGGATTCTAACCCTCAATGACGTAATGAGTATCGTGATGGGCGAATTGGTTTCCACCGAAGAGGAACAAATTGT
CCGCCGAGATGAAGATTCGTGGCTGATTGACGGTGCGACTCCGCTTGAAGACGTGATGAAAGCGTTAGAAATCGAAAGTT
TCCCGAATGCGGAAAACTATGAAACCATCGGCGGTTTTATGATGTATATGTTACGCAAAATCCCCAAAAAAACCGATTTT
GTTCTCTATGATCAGTATAAATTTGAAATTATTGATACCGAGAATTTTAAAATCGACCAATTAATGGTTTCTTTCCGCAA
AGATATTTCGAATTAG

Upstream 100 bases:

>100_bases
ACAAGCGGTCGATTTTGGGCAAAACTTGGCAATGCCGAGCATCTAAAAAACATTTAATGTTATAATTTTATACATTCAAA
CTTATCAACCAGAGGATTTT

Downstream 100 bases:

>100_bases
CATAGAAAAAGCTCCGACTTTTGGGGTGCAGATCACTTAATCGGAGCTTTGTGCTTTTACCAATGGTGTCTATGATAACC
GTAACCGACACCAATGCTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSLFEASLIILLLIVTSAVISSAEISLAGARKLKLQSMINEGDLRAEKVLKLQEQPGRFITVVQIGLNMVAILGGVVGES
AINPYFSELLSKYTQAEWVDSAASWIAFIIVTSAFVLFADLMPKRLAMTYPEKIAVRTIGVMMFCIALFKPLVLFFDWIA
NTLFKFFHVSTVRQDNMTSEDIVAVVDAGAKAGILKAQEHYLIENVFEMQERRVTSTMTTREHIVFLNRTDNREKVLETL
GEDPYSKVLICDDGLDKILGYIETHDLLTQYLKNDNVSLTDAKLLKKSLFIPDTLSLYEVLELFKSAGEDFAVIVNEYAL
VVGILTLNDVMSIVMGELVSTEEEQIVRRDEDSWLIDGATPLEDVMKALEIESFPNAENYETIGGFMMYMLRKIPKKTDF
VLYDQYKFEIIDTENFKIDQLMVSFRKDISN

Sequences:

>Translated_431_residues
MSLFEASLIILLLIVTSAVISSAEISLAGARKLKLQSMINEGDLRAEKVLKLQEQPGRFITVVQIGLNMVAILGGVVGES
AINPYFSELLSKYTQAEWVDSAASWIAFIIVTSAFVLFADLMPKRLAMTYPEKIAVRTIGVMMFCIALFKPLVLFFDWIA
NTLFKFFHVSTVRQDNMTSEDIVAVVDAGAKAGILKAQEHYLIENVFEMQERRVTSTMTTREHIVFLNRTDNREKVLETL
GEDPYSKVLICDDGLDKILGYIETHDLLTQYLKNDNVSLTDAKLLKKSLFIPDTLSLYEVLELFKSAGEDFAVIVNEYAL
VVGILTLNDVMSIVMGELVSTEEEQIVRRDEDSWLIDGATPLEDVMKALEIESFPNAENYETIGGFMMYMLRKIPKKTDF
VLYDQYKFEIIDTENFKIDQLMVSFRKDISN
>Mature_430_residues
SLFEASLIILLLIVTSAVISSAEISLAGARKLKLQSMINEGDLRAEKVLKLQEQPGRFITVVQIGLNMVAILGGVVGESA
INPYFSELLSKYTQAEWVDSAASWIAFIIVTSAFVLFADLMPKRLAMTYPEKIAVRTIGVMMFCIALFKPLVLFFDWIAN
TLFKFFHVSTVRQDNMTSEDIVAVVDAGAKAGILKAQEHYLIENVFEMQERRVTSTMTTREHIVFLNRTDNREKVLETLG
EDPYSKVLICDDGLDKILGYIETHDLLTQYLKNDNVSLTDAKLLKKSLFIPDTLSLYEVLELFKSAGEDFAVIVNEYALV
VGILTLNDVMSIVMGELVSTEEEQIVRRDEDSWLIDGATPLEDVMKALEIESFPNAENYETIGGFMMYMLRKIPKKTDFV
LYDQYKFEIIDTENFKIDQLMVSFRKDISN

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=378, Percent_Identity=24.8677248677249, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1790664, Length=418, Percent_Identity=53.11004784689, Blast_Score=476, Evalue=1e-135,
Organism=Escherichia coli, GI87082033, Length=259, Percent_Identity=30.1158301158301, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI145693175, Length=415, Percent_Identity=23.1325301204819, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788119, Length=227, Percent_Identity=24.6696035242291, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786879, Length=273, Percent_Identity=21.2454212454212, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48759; Mature: 48628

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFEASLIILLLIVTSAVISSAEISLAGARKLKLQSMINEGDLRAEKVLKLQEQPGRFI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEE
TVVQIGLNMVAILGGVVGESAINPYFSELLSKYTQAEWVDSAASWIAFIIVTSAFVLFAD
EHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMPKRLAMTYPEKIAVRTIGVMMFCIALFKPLVLFFDWIANTLFKFFHVSTVRQDNMTSE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
DIVAVVDAGAKAGILKAQEHYLIENVFEMQERRVTSTMTTREHIVFLNRTDNREKVLETL
HHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHH
GEDPYSKVLICDDGLDKILGYIETHDLLTQYLKNDNVSLTDAKLLKKSLFIPDTLSLYEV
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHH
LELFKSAGEDFAVIVNEYALVVGILTLNDVMSIVMGELVSTEEEQIVRRDEDSWLIDGAT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEECCCC
PLEDVMKALEIESFPNAENYETIGGFMMYMLRKIPKKTDFVLYDQYKFEIIDTENFKIDQ
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECEEEEEEECCCCHHHH
LMVSFRKDISN
HHHHHHHHHCC
>Mature Secondary Structure 
SLFEASLIILLLIVTSAVISSAEISLAGARKLKLQSMINEGDLRAEKVLKLQEQPGRFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEE
TVVQIGLNMVAILGGVVGESAINPYFSELLSKYTQAEWVDSAASWIAFIIVTSAFVLFAD
EHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMPKRLAMTYPEKIAVRTIGVMMFCIALFKPLVLFFDWIANTLFKFFHVSTVRQDNMTSE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
DIVAVVDAGAKAGILKAQEHYLIENVFEMQERRVTSTMTTREHIVFLNRTDNREKVLETL
HHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHH
GEDPYSKVLICDDGLDKILGYIETHDLLTQYLKNDNVSLTDAKLLKKSLFIPDTLSLYEV
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHH
LELFKSAGEDFAVIVNEYALVVGILTLNDVMSIVMGELVSTEEEQIVRRDEDSWLIDGAT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEECCCC
PLEDVMKALEIESFPNAENYETIGGFMMYMLRKIPKKTDFVLYDQYKFEIIDTENFKIDQ
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECEEEEEEECCCCHHHH
LMVSFRKDISN
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]