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The map label for this gene is fis [H]

Identifier: 126207678

GI number: 126207678

Start: 210047

End: 210343

Strand: Direct

Name: fis [H]

Synonym: APL_0190

Alternate gene names: 126207678

Gene position: 210047-210343 (Clockwise)

Preceding gene: 126207677

Following gene: 126207684

Centisome position: 9.23

GC content: 36.36

Gene sequence:

>297_bases
ATGTTAGAACAACAACCTGTACAAAACCCATTAACGGTATCAATGTTAAATGCCCAAGCACAACAAGTGAACAAACCACT
TCGTGATAATGTAAAAGCGGCATTAAAAAATTATTTATCTCAATTAAACGGTGAAGATCCGACAGAATTATACGAGTTAG
TATTATCTGAAATCGAACACCCGATGTTAGATATGGTTATGCAATATACTCGCGGTAACCAAACACGTGCGGCAACCATG
TTAGGTATTAACCGCGGTACGTTACGCAAAAAATTAAAAAAATACGGTATGGGTTAA

Upstream 100 bases:

>100_bases
TACTTTCAATGCGTTGGATTCGACAAAAGAACAATCACTCGCATTGGAAGATTTTATGAAATCGATTCGGTAGAATCCTA
TTTTAGTTGGATAGAGGACA

Downstream 100 bases:

>100_bases
TTTTTAACTCATATTTTTTCCATAAAAAAGGCTATTCCGTTGAATAGCCTTTTTTGTATTTTGTTTATAACGAATTAAAG
AAAATCACTAAGATAATAAC

Product: DNA-binding protein Fis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 98; Mature: 98

Protein sequence:

>98_residues
MLEQQPVQNPLTVSMLNAQAQQVNKPLRDNVKAALKNYLSQLNGEDPTELYELVLSEIEHPMLDMVMQYTRGNQTRAATM
LGINRGTLRKKLKKYGMG

Sequences:

>Translated_98_residues
MLEQQPVQNPLTVSMLNAQAQQVNKPLRDNVKAALKNYLSQLNGEDPTELYELVLSEIEHPMLDMVMQYTRGNQTRAATM
LGINRGTLRKKLKKYGMG
>Mature_98_residues
MLEQQPVQNPLTVSMLNAQAQQVNKPLRDNVKAALKNYLSQLNGEDPTELYELVLSEIEHPMLDMVMQYTRGNQTRAATM
LGINRGTLRKKLKKYGMG

Specific function: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters [H]

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family [H]

Homologues:

Organism=Escherichia coli, GI1789661, Length=97, Percent_Identity=71.1340206185567, Blast_Score=144, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197 [H]

Pfam domain/function: PF02954 HTH_8 [H]

EC number: NA

Molecular weight: Translated: 11118; Mature: 11118

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQQPVQNPLTVSMLNAQAQQVNKPLRDNVKAALKNYLSQLNGEDPTELYELVLSEIEH
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
PMLDMVMQYTRGNQTRAATMLGINRGTLRKKLKKYGMG
HHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLEQQPVQNPLTVSMLNAQAQQVNKPLRDNVKAALKNYLSQLNGEDPTELYELVLSEIEH
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
PMLDMVMQYTRGNQTRAATMLGINRGTLRKKLKKYGMG
HHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA