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The map label for this gene is sixA [H]

Identifier: 126207676

GI number: 126207676

Start: 208343

End: 208834

Strand: Direct

Name: sixA [H]

Synonym: APL_0188

Alternate gene names: 126207676

Gene position: 208343-208834 (Clockwise)

Preceding gene: 126207670

Following gene: 126207677

Centisome position: 9.16

GC content: 44.72

Gene sequence:

>492_bases
ATGAATATTTGGATTATGCGCCACGGCGAAGCCGGGTTTAATGCGGCGACGGACAGCGAGCGCCCTTTAACGGAAAACGG
GCGAAAAACGGCTTATAAACAGGGTCAATGGTTGGCAAAACGTTTTCTTGAACAAAGTATCGTACCGGATAAAGTGATTG
TGAGTCCGTATCTGCGTGCGCAACAGACTTTCGAGGCTTTGAACGAAGGGATGCAAGCGGTCGATTTTAAGCGAAATTTG
GTAAATTCGTCGATAGAAATTTGGGAGGGCGTTACGCCCGGCGGAGATCCGGAGAACGTTAAAAACTACTTGGATTTCTT
ACGTGAAGAAGGGGCGAAGAATATTCTAATCATATCGCATTTACCGTTAGTGTATGACTTGGTCGTCAGTTTGACGCAAC
ACCAAGATAGCGTACATTTTTATCCGGCGGTAATTGCGGAAATCGATTGGAAAACAGACTTTGGTAAAGTTTCAGCAATT
GAATATCCTTAA

Upstream 100 bases:

>100_bases
AAATTGAAAATTCTTTTCATCGGCGGTATTTTAACGCCTTAAACGCAGAGTATTATACGCTTAAATCGTGTTGGTTTAAA
TACAGTAATGAGGTTTTCCT

Downstream 100 bases:

>100_bases
ATGATAGGTTTTAGGGGGATAAAAAAATTATTTTTATTTTTTTAGAAATTGTCCAATAAATAGGCTTCCCAATTATGTAA
AAAGTGCGTATCATACGCAC

Product: phosphohistidine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MNIWIMRHGEAGFNAATDSERPLTENGRKTAYKQGQWLAKRFLEQSIVPDKVIVSPYLRAQQTFEALNEGMQAVDFKRNL
VNSSIEIWEGVTPGGDPENVKNYLDFLREEGAKNILIISHLPLVYDLVVSLTQHQDSVHFYPAVIAEIDWKTDFGKVSAI
EYP

Sequences:

>Translated_163_residues
MNIWIMRHGEAGFNAATDSERPLTENGRKTAYKQGQWLAKRFLEQSIVPDKVIVSPYLRAQQTFEALNEGMQAVDFKRNL
VNSSIEIWEGVTPGGDPENVKNYLDFLREEGAKNILIISHLPLVYDLVVSLTQHQDSVHFYPAVIAEIDWKTDFGKVSAI
EYP
>Mature_163_residues
MNIWIMRHGEAGFNAATDSERPLTENGRKTAYKQGQWLAKRFLEQSIVPDKVIVSPYLRAQQTFEALNEGMQAVDFKRNL
VNSSIEIWEGVTPGGDPENVKNYLDFLREEGAKNILIISHLPLVYDLVVSLTQHQDSVHFYPAVIAEIDWKTDFGKVSAI
EYP

Specific function: Exhibits Phosphohistidine Phosphatase Activity Towards The Hpt Domain Of The Arcb Sensor Involved In The Multistep His- Asp Phosphorelay. [C]

COG id: COG2062

COG function: function code T; Phosphohistidine phosphatase SixA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sixA phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788681, Length=148, Percent_Identity=38.5135135135135, Blast_Score=101, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR004449 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 3.1.3.- [C]

Molecular weight: Translated: 18537; Mature: 18537

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIWIMRHGEAGFNAATDSERPLTENGRKTAYKQGQWLAKRFLEQSIVPDKVIVSPYLRA
CEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QQTFEALNEGMQAVDFKRNLVNSSIEIWEGVTPGGDPENVKNYLDFLREEGAKNILIISH
HHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEC
LPLVYDLVVSLTQHQDSVHFYPAVIAEIDWKTDFGKVSAIEYP
HHHHHHHHHHHHHCCCCCEEHHHHEEEECCCCCCCCEEEECCC
>Mature Secondary Structure
MNIWIMRHGEAGFNAATDSERPLTENGRKTAYKQGQWLAKRFLEQSIVPDKVIVSPYLRA
CEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QQTFEALNEGMQAVDFKRNLVNSSIEIWEGVTPGGDPENVKNYLDFLREEGAKNILIISH
HHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEC
LPLVYDLVVSLTQHQDSVHFYPAVIAEIDWKTDFGKVSAIEYP
HHHHHHHHHHHHHCCCCCEEHHHHEEEECCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]