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The map label for this gene is nqrA

Identifier: 126207638

GI number: 126207638

Start: 168086

End: 169435

Strand: Direct

Name: nqrA

Synonym: APL_0150

Alternate gene names: 126207638

Gene position: 168086-169435 (Clockwise)

Preceding gene: 126207636

Following gene: 126207639

Centisome position: 7.39

GC content: 44.67

Gene sequence:

>1350_bases
ATGATTACAATCAAGAAAGGCTTGGATTTACCTATCGCAGGTACACCGGCACAAGTAATCCATAACGGCAATACCGTTAA
TGAAGTTGCGATGCTTGGCGAAGAATATGTGGGTATGCGTCCTTCAATGAAAGTTCGTGAAGGCGATGTAGTGAAAAAAG
GTCAGGTTCTTTTTGAAGATAAAAAGAATCCGGGCGTTGTATTTACTGCTCCTGCAAGCGGTACCGTGGTTACTATTAAC
CGCGGTGAAAAGCGTGTTCTTCAGTCGGTCGTGATTAAAGTTGAGGGTGATGAGCAAATTACCTTTACTCGCTATGAAGC
TGCGCAATTAGCGTCGCTATCAGCCGAGCAAGTGAAACAAAATCTTATCGAATCGGGTTTATGGACTGCATTCCGTACTC
GTCCGTTCAGTAAGGTTCCCGCATTGGACGCGATTCCGTCATCAATCTTTGTCAATGCAATGGATACCAATCCGTTAGCG
GCGGATCCGGAAGTGGTTTTAAAAGAGTACGAAACCGATTTTAAAGACGGTTTAACTGTTTTAACCCGTTTATTTAACGG
TCAAAAACCGGTTTACTTATGTAAAGACGCGGACAGCAATATCCCGTTAAGTCCGGCGATTGAAGGTATCACAATTAAGT
CGTTTAGCGGTGTTCATCCTGCCGGTTTAGTCGGTACGCATATCCACTTTGTTGATCCCGTAGGGGCGACCAAACAAGTT
TGGCACTTAAATTATCAAGATGTGATTGCTATCGGTAAATTATTTACTACAGGCGAACTCTTTACCGACCGTATTATTTC
GCTTGCCGGTCCGCAAGTGAAAAATCCTCGTTTAGTACGTACGCGTCTTGGTGCGAATCTTTCCCAATTAACCGCAAATG
AGTTAAATGCCGGTGAAAACCGTGTGATTTCAGGTTCGGTATTGAGCGGTGCGACTGCGGCGGGTCCGGTTGATTACTTA
GGCCGTTACGCATTACAAGTATCCGTACTGGCGGAAGGTCGTGAGAAAGAGTTATTCGGTTGGATTATGCCGGGTTCGGA
TAAATTCTCCATTACCCGTACCGTGTTAGGCCACTTCGGTAAAAAATTATTTAACTTCACTACGGCAGTTCACGGCGGTG
AACGTGCAATGGTGCCAATCGGTGCGTATGAGCGTGTAATGCCGTTAGATATTATTCCTACGTTATTACTTCGTGATTTA
GCTGCCGGCGATACCGATTCTGCACAAAACTTAGGTTGTTTAGAGCTGGATGAAGAAGATTTGGCATTATGTACTTATGT
TTGCCCGGGTAAAAATAACTACGGTCCGATGTTACGTGCTGCGTTAGAGAAGATCGAGAAGGAAGGTTAA

Upstream 100 bases:

>100_bases
GTGGGGGAATTCGTTTATTTCTATCTAAGTTACGGCTCAAGAGAAGCGATTGCGATTTTCGCAATCATATTTTTAACCCA
ACAAAAGTAGTGCAAATAAT

Downstream 100 bases:

>100_bases
GAAAATGGGTTTAAAAAATCTTTTTGAAAAGATGGAACCTGCGTTTCACAAAGGTGGAAAATATGAGAAATGGTACACGC
TTTTTGAAGCGACATATACC

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MITIKKGLDLPIAGTPAQVIHNGNTVNEVAMLGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVVFTAPASGTVVTIN
RGEKRVLQSVVIKVEGDEQITFTRYEAAQLASLSAEQVKQNLIESGLWTAFRTRPFSKVPALDAIPSSIFVNAMDTNPLA
ADPEVVLKEYETDFKDGLTVLTRLFNGQKPVYLCKDADSNIPLSPAIEGITIKSFSGVHPAGLVGTHIHFVDPVGATKQV
WHLNYQDVIAIGKLFTTGELFTDRIISLAGPQVKNPRLVRTRLGANLSQLTANELNAGENRVISGSVLSGATAAGPVDYL
GRYALQVSVLAEGREKELFGWIMPGSDKFSITRTVLGHFGKKLFNFTTAVHGGERAMVPIGAYERVMPLDIIPTLLLRDL
AAGDTDSAQNLGCLELDEEDLALCTYVCPGKNNYGPMLRAALEKIEKEG

Sequences:

>Translated_449_residues
MITIKKGLDLPIAGTPAQVIHNGNTVNEVAMLGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVVFTAPASGTVVTIN
RGEKRVLQSVVIKVEGDEQITFTRYEAAQLASLSAEQVKQNLIESGLWTAFRTRPFSKVPALDAIPSSIFVNAMDTNPLA
ADPEVVLKEYETDFKDGLTVLTRLFNGQKPVYLCKDADSNIPLSPAIEGITIKSFSGVHPAGLVGTHIHFVDPVGATKQV
WHLNYQDVIAIGKLFTTGELFTDRIISLAGPQVKNPRLVRTRLGANLSQLTANELNAGENRVISGSVLSGATAAGPVDYL
GRYALQVSVLAEGREKELFGWIMPGSDKFSITRTVLGHFGKKLFNFTTAVHGGERAMVPIGAYERVMPLDIIPTLLLRDL
AAGDTDSAQNLGCLELDEEDLALCTYVCPGKNNYGPMLRAALEKIEKEG
>Mature_449_residues
MITIKKGLDLPIAGTPAQVIHNGNTVNEVAMLGEEYVGMRPSMKVREGDVVKKGQVLFEDKKNPGVVFTAPASGTVVTIN
RGEKRVLQSVVIKVEGDEQITFTRYEAAQLASLSAEQVKQNLIESGLWTAFRTRPFSKVPALDAIPSSIFVNAMDTNPLA
ADPEVVLKEYETDFKDGLTVLTRLFNGQKPVYLCKDADSNIPLSPAIEGITIKSFSGVHPAGLVGTHIHFVDPVGATKQV
WHLNYQDVIAIGKLFTTGELFTDRIISLAGPQVKNPRLVRTRLGANLSQLTANELNAGENRVISGSVLSGATAAGPVDYL
GRYALQVSVLAEGREKELFGWIMPGSDKFSITRTVLGHFGKKLFNFTTAVHGGERAMVPIGAYERVMPLDIIPTLLLRDL
AAGDTDSAQNLGCLELDEEDLALCTYVCPGKNNYGPMLRAALEKIEKEG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRA_ACTP2 (A3MYM2)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001052863.1
- ProteinModelPortal:   A3MYM2
- STRING:   A3MYM2
- GeneID:   4848604
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_0150
- eggNOG:   COG1726
- HOGENOM:   HBG413878
- OMA:   EYGPILR
- ProtClustDB:   PRK05352
- BioCyc:   APLE416269:APL_0150-MONOMER
- HAMAP:   MF_00425
- InterPro:   IPR008703
- InterPro:   IPR022615
- TIGRFAMs:   TIGR01936

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB

EC number: NA

Molecular weight: Translated: 48604; Mature: 48604

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKKGLDLPIAGTPAQVIHNGNTVNEVAMLGEEYVGMRPSMKVREGDVVKKGQVLFED
CEEECCCCCCCCCCCCHHHEECCCCHHHHHHHHHHHCCCCCCCEECCCCCEECCCEEEEC
KKNPGVVFTAPASGTVVTINRGEKRVLQSVVIKVEGDEQITFTRYEAAQLASLSAEQVKQ
CCCCCEEEECCCCCEEEEEECCHHHHHHHHEEEECCCCEEEEEEHHHHHHHHCCHHHHHH
NLIESGLWTAFRTRPFSKVPALDAIPSSIFVNAMDTNPLAADPEVVLKEYETDFKDGLTV
HHHHHCCHHHHHCCCCCCCCCHHCCCCCEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHH
LTRLFNGQKPVYLCKDADSNIPLSPAIEGITIKSFSGVHPAGLVGTHIHFVDPVGATKQV
HHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCEEECEEEEECCCCCCCCE
WHLNYQDVIAIGKLFTTGELFTDRIISLAGPQVKNPRLVRTRLGANLSQLTANELNAGEN
EECCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEHHHHCCCHHHHHHHHCCCCCC
RVISGSVLSGATAAGPVDYLGRYALQVSVLAEGREKELFGWIMPGSDKFSITRTVLGHFG
EEEECCHHCCCCCCCCHHHHHHHHEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHH
KKLFNFTTAVHGGERAMVPIGAYERVMPLDIIPTLLLRDLAAGDTDSAQNLGCLELDEED
HHHHHHHHHEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
LALCTYVCPGKNNYGPMLRAALEKIEKEG
EEEEEEECCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MITIKKGLDLPIAGTPAQVIHNGNTVNEVAMLGEEYVGMRPSMKVREGDVVKKGQVLFED
CEEECCCCCCCCCCCCHHHEECCCCHHHHHHHHHHHCCCCCCCEECCCCCEECCCEEEEC
KKNPGVVFTAPASGTVVTINRGEKRVLQSVVIKVEGDEQITFTRYEAAQLASLSAEQVKQ
CCCCCEEEECCCCCEEEEEECCHHHHHHHHEEEECCCCEEEEEEHHHHHHHHCCHHHHHH
NLIESGLWTAFRTRPFSKVPALDAIPSSIFVNAMDTNPLAADPEVVLKEYETDFKDGLTV
HHHHHCCHHHHHCCCCCCCCCHHCCCCCEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHH
LTRLFNGQKPVYLCKDADSNIPLSPAIEGITIKSFSGVHPAGLVGTHIHFVDPVGATKQV
HHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCEEECEEEEECCCCCCCCE
WHLNYQDVIAIGKLFTTGELFTDRIISLAGPQVKNPRLVRTRLGANLSQLTANELNAGEN
EECCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEHHHHCCCHHHHHHHHCCCCCC
RVISGSVLSGATAAGPVDYLGRYALQVSVLAEGREKELFGWIMPGSDKFSITRTVLGHFG
EEEECCHHCCCCCCCCHHHHHHHHEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHH
KKLFNFTTAVHGGERAMVPIGAYERVMPLDIIPTLLLRDLAAGDTDSAQNLGCLELDEED
HHHHHHHHHEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
LALCTYVCPGKNNYGPMLRAALEKIEKEG
EEEEEEECCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA