Click here to switch to the map view.

The map label for this gene is nrdB [H]

Identifier: 126207635

GI number: 126207635

Start: 164268

End: 165245

Strand: Direct

Name: nrdB [H]

Synonym: APL_0147

Alternate gene names: 126207635

Gene position: 164268-165245 (Clockwise)

Preceding gene: 126207631

Following gene: 126207636

Centisome position: 7.22

GC content: 38.45

Gene sequence:

>978_bases
ATGTCTAGAAATCTCTTTGAAAAACGCTTGAATATCAAGCCGTATGAATACCCCGAATTATTGGAATTTAAAGATGCTAT
TCGCCATTCCTATTGGCTACATACGGAATTTAATTTTACCGGTGATATTCAGAACTACCGTATCGATATCAATGATCACG
AACGTCACGTATTGACTCGAGCGATGTTGGCGATTTCCCAAGTGGAAGTGAACGTAAAACGCTTCTGGGGTGAGTTGTAT
CGTTATTTTCCGAAACCGGAAATGGATGATGTCGGCGGTACTTTCGCCGAATCGGAAGTTCGTCATAAAGACGCCTACTC
GTTTTTATTAGAAAAATTAGGCCTAAACGAAATGTTTAGCCAAATCCAAGATATTGAACCGTTAATGAACCGCATCCGTT
ATATGGAATCGTTCATGAAGGATAAAGATGCGGGTAAAGGCGAATTCGTACTTTCACTCGTTTTATTCTCACTTTTCGTA
GAACATATTTCCTTATTCGGTCAGTTCTTGATCATGATGTCGTTCAATAAGCATAAAAACCTGTTTAAAGGGATTTCGAA
TGCGGTTGAAGCGACCTCAAAAGAAGAAGAAATTCACGGTAAATTCGGTATTGCGTTATACGAAATTTTACGCGAAGAAC
ACAGCGAACTGTTCACACCGGAATTTTTTGAAGATTTAAAAACCTTATCAAGCCAAGCATTTGAAGCGGAATGCGGGATT
TTAGATTGGATTTTTGAAGAGGGCGATTTAAGTTTTATCAGCCGTGAAGAAGTGGAAAACTACATTCGTAGCCGTTATAA
CAACTCGTTAATGACGCTCGGTTTAGAACCGCCGTACGATGTAAATCCAGAATTATTAAAAGAAACCGAGTGGTTTGATA
TTGAAATTCTATCGACGAAAGAAACGGATTTCTTTAACAAACGTAGTACCGATTACAGCAAAAAAATGAAGCAGATTACC
GCAGATGACTTATTCTAA

Upstream 100 bases:

>100_bases
CAAGAAACTAACTAAAAAGAGAGTTTGTCAAGACTTGTGATTATAAAAATTTTTGCCTAAAATCCACGCCCATTACAACT
TAGAATCGAGCCAAGGAATT

Downstream 100 bases:

>100_bases
TTCTCGTCCTGATTTTGAATGGCTGAACGAAGACAGCCGCTTATTTTTACAACGTGGTTATTTACTTGAAGGAACCACCG
CATTAGATCGTATCCGTTTT

Product: ribonucleoside-diphosphate reductase beta chain

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSRNLFEKRLNIKPYEYPELLEFKDAIRHSYWLHTEFNFTGDIQNYRIDINDHERHVLTRAMLAISQVEVNVKRFWGELY
RYFPKPEMDDVGGTFAESEVRHKDAYSFLLEKLGLNEMFSQIQDIEPLMNRIRYMESFMKDKDAGKGEFVLSLVLFSLFV
EHISLFGQFLIMMSFNKHKNLFKGISNAVEATSKEEEIHGKFGIALYEILREEHSELFTPEFFEDLKTLSSQAFEAECGI
LDWIFEEGDLSFISREEVENYIRSRYNNSLMTLGLEPPYDVNPELLKETEWFDIEILSTKETDFFNKRSTDYSKKMKQIT
ADDLF

Sequences:

>Translated_325_residues
MSRNLFEKRLNIKPYEYPELLEFKDAIRHSYWLHTEFNFTGDIQNYRIDINDHERHVLTRAMLAISQVEVNVKRFWGELY
RYFPKPEMDDVGGTFAESEVRHKDAYSFLLEKLGLNEMFSQIQDIEPLMNRIRYMESFMKDKDAGKGEFVLSLVLFSLFV
EHISLFGQFLIMMSFNKHKNLFKGISNAVEATSKEEEIHGKFGIALYEILREEHSELFTPEFFEDLKTLSSQAFEAECGI
LDWIFEEGDLSFISREEVENYIRSRYNNSLMTLGLEPPYDVNPELLKETEWFDIEILSTKETDFFNKRSTDYSKKMKQIT
ADDLF
>Mature_324_residues
SRNLFEKRLNIKPYEYPELLEFKDAIRHSYWLHTEFNFTGDIQNYRIDINDHERHVLTRAMLAISQVEVNVKRFWGELYR
YFPKPEMDDVGGTFAESEVRHKDAYSFLLEKLGLNEMFSQIQDIEPLMNRIRYMESFMKDKDAGKGEFVLSLVLFSLFVE
HISLFGQFLIMMSFNKHKNLFKGISNAVEATSKEEEIHGKFGIALYEILREEHSELFTPEFFEDLKTLSSQAFEAECGIL
DWIFEEGDLSFISREEVENYIRSRYNNSLMTLGLEPPYDVNPELLKETEWFDIEILSTKETDFFNKRSTDYSKKMKQITA
DDLF

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 38548; Mature: 38417

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNLFEKRLNIKPYEYPELLEFKDAIRHSYWLHTEFNFTGDIQNYRIDINDHERHVLTR
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEEECCEEECCCCEEECCCCCHHHHHHH
AMLAISQVEVNVKRFWGELYRYFPKPEMDDVGGTFAESEVRHKDAYSFLLEKLGLNEMFS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
QIQDIEPLMNRIRYMESFMKDKDAGKGEFVLSLVLFSLFVEHISLFGQFLIMMSFNKHKN
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFKGISNAVEATSKEEEIHGKFGIALYEILREEHSELFTPEFFEDLKTLSSQAFEAECGI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCH
LDWIFEEGDLSFISREEVENYIRSRYNNSLMTLGLEPPYDVNPELLKETEWFDIEILSTK
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCCCCCEEEEEEECC
ETDFFNKRSTDYSKKMKQITADDLF
CCHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRNLFEKRLNIKPYEYPELLEFKDAIRHSYWLHTEFNFTGDIQNYRIDINDHERHVLTR
CCHHHHHHCCCCCCCCHHHHHHHHHHHHHEEEEEECCEEECCCCEEECCCCCHHHHHHH
AMLAISQVEVNVKRFWGELYRYFPKPEMDDVGGTFAESEVRHKDAYSFLLEKLGLNEMFS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
QIQDIEPLMNRIRYMESFMKDKDAGKGEFVLSLVLFSLFVEHISLFGQFLIMMSFNKHKN
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFKGISNAVEATSKEEEIHGKFGIALYEILREEHSELFTPEFFEDLKTLSSQAFEAECGI
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCH
LDWIFEEGDLSFISREEVENYIRSRYNNSLMTLGLEPPYDVNPELLKETEWFDIEILSTK
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHCCCCCEEEEEEECC
ETDFFNKRSTDYSKKMKQITADDLF
CCHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]