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The map label for this gene is putA [H]

Identifier: 126207594

GI number: 126207594

Start: 121566

End: 125171

Strand: Reverse

Name: putA [H]

Synonym: APL_0106

Alternate gene names: 126207594

Gene position: 125171-121566 (Counterclockwise)

Preceding gene: 126207595

Following gene: 126207593

Centisome position: 5.5

GC content: 45.31

Gene sequence:

>3606_bases
ATGCCGACAAACATTTATCCCCTTCTTCCTTCTTCAGCCGTCCTTCGTGAAAATATCAGCCGACATTATCGTATTGATGA
GGCGGAATTAGTTCAGCAGCTCTTAATTGAGGCGGAAACGGAAACATTACAGCCCGAAATCAAAAATCTCGCCCGTAAGC
TGATCGAAAAAGTACGTACCAACCGCCAAAAAGCCAGCGGTGTCGATGCATTGATGCACGAGTTTTCGCTTTCAAGCCAA
GAAGGTATCGCGTTGATGTGTTTAGCCGAAGCCTTACTGCGTATTCCTGATCAAGTGACCCGAGATAAGCTGATTAAAGA
CAAAATCGCCAAAGGCGACTGGAAATCACATATCGGAAACAGCCCTTCCTTATTTGTTAATGCCTCCGCATGGGGATTGG
TCTTTACCGGCAAATTACTGTCTCTGAATCAGCAAGCATTATCAAGTAGTCTAAATCAGCTGATTAGTAAAGCGGGAGAA
CCCGTTATTCGTAAAGGTATAGATTTTGCCATGCGTTTGCTCGGTAAACAATTTGTGACCGGCGAAACGATTCAACTCGC
CCTCAAAAATAGCGAGGCTCGTTTTAATAAAGGCTTCCGTTTTACCTACGATATGTTGGGTGAATCCGCCTTTACCGAGC
AAGACGCACAACATTATTATCAAGATTACGTAAATTCTATCCATGCGGTCGGCGCAGCCTCAAAAGGATTAGGCGTTTAT
CATTCTTCCGGCGTATCGGTTAAACTTTCGGCGATTCATCCTCGTTATAGTTTGGCACAGTATGATCGTGTTATGGATGA
ACTTTATCCTCGTTTACGTGATTTATTTCTGTTAGCAAAACGTTATAACATCGGCTTAAATATTGATGCGGAAGAAGCGA
ACCGTTTAGAAATTTCATTAGATTTAATCGATCGCTTATTAAGCGAACCCGAATTAGCCGATTTTGACGGTATCGGGATT
GTCGTACAAGCCTACCAAAAACGTTGCCGTTCGGTTATCGATTATTTAATTGCTAAAGCAAGAGAAAATAATCGTAAATT
AATGATTCGTTTAGTGAAAGGCGCTTACTGGGATTCCGAGGTAAAACTCGCTCAAACGGAAAGCGCAAGCGGTTATCCGG
TGTTTACGCGCAAAGTTCATACCGATTTGAATTACGTTGCCTGTGCGAAAAAGCTATTGGCGGCACAAGATGTGGTATTC
CCGCAATTTGCAACCCATAATGCGCAAACTTTAGCTACGATTTATCACTTAGCTAAAGGCAAACGTTTTGAATTCCAATG
CTTACACGGCATGGGCGAAACACTCTATGATCAAGTAGTCGGCAAAGAGAACCTTAATATTCAATGCCGTGTCTATGCGC
CGGTCGGATCTTATCAAACTTTATTAGCTTATTTGGTACGTCGCTTATTGGAAAACGGTTCAAACAGCTCGTTTGTCAAT
CAAATTGTCGATGAAAACGTCAGTATTGATAAGTTACTTGAAGATCCGGTAGCAAAAGCCGGTATTACCGCCGGCACCAT
GCACCCGAAAACACCGCTACCGATAAAATTATTTGCCGATCGTAAAAACTCAGCCGGTTACGAACTGAGCGATATGCACC
ATTTAGTGCAATTAGGCGCACAATTAAACGCATTGGCAGATCATAATCAATACCGTGCCGTGCCTCAAATTGCCGAGCAA
TTTTATCAAGGTTCGCAACGAAAAGTGATTTATAACCCCGCCGATCAAACTCAAATAGTCGGTGAAGTCACCTATGCTAA
CGAAACCGACGTCGAAAAAGCTTTTGCCATTGCCGAGCAAAATCAGACCGCTTGGCAAGCGACTCCAGCGGAACAAAGAG
CGGCAATTCTCGAGAAGATCGCCGATTTAATGGAAAGCAATATGCCGACTTTATTCGATCTAGCGGTTCGCGAAGCGGGT
AAAACGCTGAATAATGCGATTGCAGAAGTTAGAGAAGCGGTCGATTTTTGCCGTTATTATGCAAACCAAGTCAAACGGAA
TCCGCAGGCTTATCAAAATCCGAGAGGAATTATTGTGGCGATTAGCCCGTGGAATTTCCCACTGGCGATTTTTACCGGCG
AAGTTGTTTCCGCTTTGGTTGCCGGTAATGTCGTATTGGCGAAACCGGCGGAGCAAACTTCCTTAATGGCACATTATGCG
GTGGAATTATTTTATCAAGCAGGCGTACCGAAAAGCGTTTTACAATGCTTACCGGGTAGCGGTGCGGAAATCGGTAATAA
ATTGACCGCCGATCCTCGTGTGGACGGCGTGATTTTTACCGGCTCGACCGAAACCGCCAAAACTATTAACCGCAATTTGC
AAAAACACAGCAAAATCATACCGCTTATTGCCGAAACCGGCGGACAAAACGCCTTAATTATGGATAGTTCCGCCCTCGGC
GAACAAGTGGTGGCGGATGTGCTTAACTCGGCGTTCGATTCGGCGGGACAGCGTTGTTCCGCTCTGCGTGTGCTATATCT
ACAAGAAGATGTCGCCGATCACATTCTCACGATGCTTAAAGGCGCAATGGCGGAGTTACGTGTCGGCAAACCGCAATTGC
TAAATACCGATATCGGTCCGGTAATCGATCGCACGGCACAAAGTCGCTTACTAGCGCATATTGAAAAAATGAAAGCGGTG
GCAAAATCTTATTATCAAGTGCCGATTGCCGCAGAAGTGGAACAGAACGGGATTTTCGTACCGCCAACCTTACTTGAAAT
CGATCATATCTCGCAAATCGAACATGAAGTATTTGGCCCGGTACTACACGTGATTCGTTTTAATGCCGACCGATTCGAAC
AAATTATTGATGACATTAACTCGACCGGTTTCGGTTTAACCAGCGGTTTACATAGTCGTATCGACGCCACTATCGATCAA
TGGCTCGATAAAGTACACGCCGGTAACTTATATGTGAATCGCAATACGGTCGGTGCGGTGGTCGGAGTGCAACCGTTCGG
CGGTATGGGGCTTTCCGGTACCGGTCCGAAAGCCGGCGGACCGCTTTATCTGCAACGACTGGTAAAAAGCGAGGCTTGGA
CGCTTGCTGATTTAGAAGGCGAAGCGGTGATAGAAACGGATAAACTTGCACAAGCCGTTCGCCAAACGCTTACCGGCGAG
CAACAAAGCGAAGCGTTAGCTCTCTTGCAAACTTTACGCCAAAAATCACCGCTTGCACAAGTGTATAAAATGCAAGGTAT
CACCGGCGAAAACAACTACTTACGCTTTGAGGCTCGTCCAATGATTGCGGTAAGTAACGGCTCACTGTTCGCACAAATCA
AAGCATTGATTGCGATTGCGGTGTGCGGTAGCAAAGCGGTGGTAAAAAAAGATTCGCCGTTAGCGGAATATGCGCATCAA
TTTGCCGAATACCTAATGGTAACAGACGACTTCAATAATCTTTCAGCATTAAGTGTAATGATTGTACTTGAGCCGCTTTC
CACGCAAGAACGTCAACATTATGCCGAGTGTAACGGTTCGATTTTAACTTATGTGGAAAGCCTTGAATTGGCGCTATCAT
TGCTACCGCTGGTACATGAAAAATCGATCAGCATTAACACCGCAGCCGCCGGTGGTAATGCGACTTTGATGAGTGAAATG
GATTAG

Upstream 100 bases:

>100_bases
ACAAAGCGATTTGCCGGCAACGGCAAGTCGCTTTTTTGTTTTCGAAATGCAAACTTTTTCATAAAAACGACCGCTTGTTA
AAGCGAAACAGGAGTCCTTT

Downstream 100 bases:

>100_bases
CATGACATAAATCATGCTTAATATGTATCCCCTTAGCAATAAACTGAGGGGATTTTTATTTTCTGTTTAGCAAGTCATTT
CCTTTTCAGCTATAATTCGC

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1201; Mature: 1200

Protein sequence:

>1201_residues
MPTNIYPLLPSSAVLRENISRHYRIDEAELVQQLLIEAETETLQPEIKNLARKLIEKVRTNRQKASGVDALMHEFSLSSQ
EGIALMCLAEALLRIPDQVTRDKLIKDKIAKGDWKSHIGNSPSLFVNASAWGLVFTGKLLSLNQQALSSSLNQLISKAGE
PVIRKGIDFAMRLLGKQFVTGETIQLALKNSEARFNKGFRFTYDMLGESAFTEQDAQHYYQDYVNSIHAVGAASKGLGVY
HSSGVSVKLSAIHPRYSLAQYDRVMDELYPRLRDLFLLAKRYNIGLNIDAEEANRLEISLDLIDRLLSEPELADFDGIGI
VVQAYQKRCRSVIDYLIAKARENNRKLMIRLVKGAYWDSEVKLAQTESASGYPVFTRKVHTDLNYVACAKKLLAAQDVVF
PQFATHNAQTLATIYHLAKGKRFEFQCLHGMGETLYDQVVGKENLNIQCRVYAPVGSYQTLLAYLVRRLLENGSNSSFVN
QIVDENVSIDKLLEDPVAKAGITAGTMHPKTPLPIKLFADRKNSAGYELSDMHHLVQLGAQLNALADHNQYRAVPQIAEQ
FYQGSQRKVIYNPADQTQIVGEVTYANETDVEKAFAIAEQNQTAWQATPAEQRAAILEKIADLMESNMPTLFDLAVREAG
KTLNNAIAEVREAVDFCRYYANQVKRNPQAYQNPRGIIVAISPWNFPLAIFTGEVVSALVAGNVVLAKPAEQTSLMAHYA
VELFYQAGVPKSVLQCLPGSGAEIGNKLTADPRVDGVIFTGSTETAKTINRNLQKHSKIIPLIAETGGQNALIMDSSALG
EQVVADVLNSAFDSAGQRCSALRVLYLQEDVADHILTMLKGAMAELRVGKPQLLNTDIGPVIDRTAQSRLLAHIEKMKAV
AKSYYQVPIAAEVEQNGIFVPPTLLEIDHISQIEHEVFGPVLHVIRFNADRFEQIIDDINSTGFGLTSGLHSRIDATIDQ
WLDKVHAGNLYVNRNTVGAVVGVQPFGGMGLSGTGPKAGGPLYLQRLVKSEAWTLADLEGEAVIETDKLAQAVRQTLTGE
QQSEALALLQTLRQKSPLAQVYKMQGITGENNYLRFEARPMIAVSNGSLFAQIKALIAIAVCGSKAVVKKDSPLAEYAHQ
FAEYLMVTDDFNNLSALSVMIVLEPLSTQERQHYAECNGSILTYVESLELALSLLPLVHEKSISINTAAAGGNATLMSEM
D

Sequences:

>Translated_1201_residues
MPTNIYPLLPSSAVLRENISRHYRIDEAELVQQLLIEAETETLQPEIKNLARKLIEKVRTNRQKASGVDALMHEFSLSSQ
EGIALMCLAEALLRIPDQVTRDKLIKDKIAKGDWKSHIGNSPSLFVNASAWGLVFTGKLLSLNQQALSSSLNQLISKAGE
PVIRKGIDFAMRLLGKQFVTGETIQLALKNSEARFNKGFRFTYDMLGESAFTEQDAQHYYQDYVNSIHAVGAASKGLGVY
HSSGVSVKLSAIHPRYSLAQYDRVMDELYPRLRDLFLLAKRYNIGLNIDAEEANRLEISLDLIDRLLSEPELADFDGIGI
VVQAYQKRCRSVIDYLIAKARENNRKLMIRLVKGAYWDSEVKLAQTESASGYPVFTRKVHTDLNYVACAKKLLAAQDVVF
PQFATHNAQTLATIYHLAKGKRFEFQCLHGMGETLYDQVVGKENLNIQCRVYAPVGSYQTLLAYLVRRLLENGSNSSFVN
QIVDENVSIDKLLEDPVAKAGITAGTMHPKTPLPIKLFADRKNSAGYELSDMHHLVQLGAQLNALADHNQYRAVPQIAEQ
FYQGSQRKVIYNPADQTQIVGEVTYANETDVEKAFAIAEQNQTAWQATPAEQRAAILEKIADLMESNMPTLFDLAVREAG
KTLNNAIAEVREAVDFCRYYANQVKRNPQAYQNPRGIIVAISPWNFPLAIFTGEVVSALVAGNVVLAKPAEQTSLMAHYA
VELFYQAGVPKSVLQCLPGSGAEIGNKLTADPRVDGVIFTGSTETAKTINRNLQKHSKIIPLIAETGGQNALIMDSSALG
EQVVADVLNSAFDSAGQRCSALRVLYLQEDVADHILTMLKGAMAELRVGKPQLLNTDIGPVIDRTAQSRLLAHIEKMKAV
AKSYYQVPIAAEVEQNGIFVPPTLLEIDHISQIEHEVFGPVLHVIRFNADRFEQIIDDINSTGFGLTSGLHSRIDATIDQ
WLDKVHAGNLYVNRNTVGAVVGVQPFGGMGLSGTGPKAGGPLYLQRLVKSEAWTLADLEGEAVIETDKLAQAVRQTLTGE
QQSEALALLQTLRQKSPLAQVYKMQGITGENNYLRFEARPMIAVSNGSLFAQIKALIAIAVCGSKAVVKKDSPLAEYAHQ
FAEYLMVTDDFNNLSALSVMIVLEPLSTQERQHYAECNGSILTYVESLELALSLLPLVHEKSISINTAAAGGNATLMSEM
D
>Mature_1200_residues
PTNIYPLLPSSAVLRENISRHYRIDEAELVQQLLIEAETETLQPEIKNLARKLIEKVRTNRQKASGVDALMHEFSLSSQE
GIALMCLAEALLRIPDQVTRDKLIKDKIAKGDWKSHIGNSPSLFVNASAWGLVFTGKLLSLNQQALSSSLNQLISKAGEP
VIRKGIDFAMRLLGKQFVTGETIQLALKNSEARFNKGFRFTYDMLGESAFTEQDAQHYYQDYVNSIHAVGAASKGLGVYH
SSGVSVKLSAIHPRYSLAQYDRVMDELYPRLRDLFLLAKRYNIGLNIDAEEANRLEISLDLIDRLLSEPELADFDGIGIV
VQAYQKRCRSVIDYLIAKARENNRKLMIRLVKGAYWDSEVKLAQTESASGYPVFTRKVHTDLNYVACAKKLLAAQDVVFP
QFATHNAQTLATIYHLAKGKRFEFQCLHGMGETLYDQVVGKENLNIQCRVYAPVGSYQTLLAYLVRRLLENGSNSSFVNQ
IVDENVSIDKLLEDPVAKAGITAGTMHPKTPLPIKLFADRKNSAGYELSDMHHLVQLGAQLNALADHNQYRAVPQIAEQF
YQGSQRKVIYNPADQTQIVGEVTYANETDVEKAFAIAEQNQTAWQATPAEQRAAILEKIADLMESNMPTLFDLAVREAGK
TLNNAIAEVREAVDFCRYYANQVKRNPQAYQNPRGIIVAISPWNFPLAIFTGEVVSALVAGNVVLAKPAEQTSLMAHYAV
ELFYQAGVPKSVLQCLPGSGAEIGNKLTADPRVDGVIFTGSTETAKTINRNLQKHSKIIPLIAETGGQNALIMDSSALGE
QVVADVLNSAFDSAGQRCSALRVLYLQEDVADHILTMLKGAMAELRVGKPQLLNTDIGPVIDRTAQSRLLAHIEKMKAVA
KSYYQVPIAAEVEQNGIFVPPTLLEIDHISQIEHEVFGPVLHVIRFNADRFEQIIDDINSTGFGLTSGLHSRIDATIDQW
LDKVHAGNLYVNRNTVGAVVGVQPFGGMGLSGTGPKAGGPLYLQRLVKSEAWTLADLEGEAVIETDKLAQAVRQTLTGEQ
QSEALALLQTLRQKSPLAQVYKMQGITGENNYLRFEARPMIAVSNGSLFAQIKALIAIAVCGSKAVVKKDSPLAEYAHQF
AEYLMVTDDFNNLSALSVMIVLEPLSTQERQHYAECNGSILTYVESLELALSLLPLVHEKSISINTAAAGGNATLMSEMD

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=471, Percent_Identity=31.2101910828025, Blast_Score=190, Evalue=9e-48,
Organism=Homo sapiens, GI25777734, Length=471, Percent_Identity=31.2101910828025, Blast_Score=190, Evalue=9e-48,
Organism=Homo sapiens, GI238859541, Length=471, Percent_Identity=31.2101910828025, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI153266822, Length=450, Percent_Identity=29.5555555555556, Blast_Score=184, Evalue=5e-46,
Organism=Homo sapiens, GI188035924, Length=479, Percent_Identity=30.4801670146138, Blast_Score=175, Evalue=3e-43,
Organism=Homo sapiens, GI310128103, Length=479, Percent_Identity=30.4801670146138, Blast_Score=174, Evalue=4e-43,
Organism=Homo sapiens, GI310128093, Length=474, Percent_Identity=30.5907172995781, Blast_Score=173, Evalue=1e-42,
Organism=Homo sapiens, GI21614513, Length=461, Percent_Identity=29.9349240780911, Blast_Score=172, Evalue=2e-42,
Organism=Homo sapiens, GI21361176, Length=450, Percent_Identity=29.3333333333333, Blast_Score=172, Evalue=2e-42,
Organism=Homo sapiens, GI25777724, Length=451, Percent_Identity=28.3813747228381, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI12007648, Length=454, Percent_Identity=27.7533039647577, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI238814322, Length=419, Percent_Identity=28.1622911694511, Blast_Score=164, Evalue=7e-40,
Organism=Homo sapiens, GI25777730, Length=441, Percent_Identity=28.3446712018141, Blast_Score=162, Evalue=3e-39,
Organism=Homo sapiens, GI25777732, Length=465, Percent_Identity=28.6021505376344, Blast_Score=160, Evalue=6e-39,
Organism=Homo sapiens, GI25777728, Length=408, Percent_Identity=28.1862745098039, Blast_Score=153, Evalue=9e-37,
Organism=Homo sapiens, GI310128091, Length=390, Percent_Identity=31.025641025641, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI4507229, Length=412, Percent_Identity=30.5825242718447, Blast_Score=148, Evalue=3e-35,
Organism=Homo sapiens, GI115387104, Length=468, Percent_Identity=25.2136752136752, Blast_Score=144, Evalue=5e-34,
Organism=Homo sapiens, GI25777721, Length=425, Percent_Identity=29.4117647058824, Blast_Score=138, Evalue=3e-32,
Organism=Homo sapiens, GI25952152, Length=442, Percent_Identity=26.0180995475113, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI25777726, Length=451, Percent_Identity=25.2771618625277, Blast_Score=125, Evalue=3e-28,
Organism=Homo sapiens, GI11095441, Length=421, Percent_Identity=24.9406175771971, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI310128089, Length=333, Percent_Identity=30.3303303303303, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI310128095, Length=316, Percent_Identity=30.379746835443, Blast_Score=114, Evalue=6e-25,
Organism=Homo sapiens, GI71773324, Length=396, Percent_Identity=25.2525252525253, Blast_Score=112, Evalue=3e-24,
Organism=Homo sapiens, GI310128087, Length=291, Percent_Identity=30.5841924398625, Blast_Score=110, Evalue=6e-24,
Organism=Homo sapiens, GI4502043, Length=413, Percent_Identity=25.181598062954, Blast_Score=110, Evalue=7e-24,
Organism=Homo sapiens, GI238814371, Length=413, Percent_Identity=25.181598062954, Blast_Score=110, Evalue=7e-24,
Organism=Homo sapiens, GI310128097, Length=263, Percent_Identity=31.9391634980989, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI206597441, Length=345, Percent_Identity=26.0869565217391, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI206597439, Length=345, Percent_Identity=26.0869565217391, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI22907049, Length=345, Percent_Identity=26.0869565217391, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI301500698, Length=444, Percent_Identity=24.5495495495495, Blast_Score=101, Evalue=5e-21,
Organism=Homo sapiens, GI73695881, Length=329, Percent_Identity=25.531914893617, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI73695879, Length=329, Percent_Identity=25.531914893617, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI310128099, Length=240, Percent_Identity=29.5833333333333, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI310128101, Length=240, Percent_Identity=29.5833333333333, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI4557303, Length=348, Percent_Identity=23.8505747126437, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI73466520, Length=348, Percent_Identity=23.8505747126437, Blast_Score=91, Evalue=6e-18,
Organism=Escherichia coli, GI1787250, Length=1255, Percent_Identity=51.7131474103586, Blast_Score=1155, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=468, Percent_Identity=30.982905982906, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI87081896, Length=480, Percent_Identity=30.625, Blast_Score=177, Evalue=4e-45,
Organism=Escherichia coli, GI1788042, Length=485, Percent_Identity=32.1649484536082, Blast_Score=176, Evalue=7e-45,
Organism=Escherichia coli, GI1787715, Length=453, Percent_Identity=30.0220750551876, Blast_Score=166, Evalue=1e-41,
Organism=Escherichia coli, GI1787684, Length=466, Percent_Identity=28.5407725321888, Blast_Score=164, Evalue=4e-41,
Organism=Escherichia coli, GI1787558, Length=446, Percent_Identity=28.47533632287, Blast_Score=151, Evalue=2e-37,
Organism=Escherichia coli, GI1786504, Length=448, Percent_Identity=26.1160714285714, Blast_Score=149, Evalue=1e-36,
Organism=Escherichia coli, GI87082295, Length=447, Percent_Identity=27.2930648769575, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI87081926, Length=438, Percent_Identity=25.7990867579909, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI1787653, Length=395, Percent_Identity=21.5189873417722, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17534447, Length=471, Percent_Identity=31.8471337579618, Blast_Score=206, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI133930964, Length=449, Percent_Identity=30.5122494432071, Blast_Score=187, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI115534176, Length=506, Percent_Identity=30.6324110671937, Blast_Score=177, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI115532534, Length=377, Percent_Identity=32.0954907161804, Blast_Score=175, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI32564151, Length=416, Percent_Identity=30.2884615384615, Blast_Score=167, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17562198, Length=450, Percent_Identity=29.7777777777778, Blast_Score=166, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI25144435, Length=449, Percent_Identity=29.3986636971047, Blast_Score=160, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI32564736, Length=408, Percent_Identity=29.9019607843137, Blast_Score=151, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI25143874, Length=433, Percent_Identity=26.7898383371824, Blast_Score=144, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=433, Percent_Identity=26.7898383371824, Blast_Score=143, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17551164, Length=427, Percent_Identity=28.5714285714286, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71986308, Length=424, Percent_Identity=27.122641509434, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71990744, Length=309, Percent_Identity=31.3915857605178, Blast_Score=134, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71995606, Length=442, Percent_Identity=26.9230769230769, Blast_Score=129, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17534119, Length=475, Percent_Identity=25.6842105263158, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71995613, Length=398, Percent_Identity=26.6331658291457, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25146391, Length=334, Percent_Identity=24.5508982035928, Blast_Score=109, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI32566756, Length=334, Percent_Identity=24.5508982035928, Blast_Score=109, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI25146394, Length=334, Percent_Identity=24.5508982035928, Blast_Score=109, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17564084, Length=330, Percent_Identity=25.4545454545455, Blast_Score=106, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6320917, Length=461, Percent_Identity=30.58568329718, Blast_Score=183, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6325196, Length=468, Percent_Identity=29.7008547008547, Blast_Score=182, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6323821, Length=472, Percent_Identity=31.3559322033898, Blast_Score=182, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6321826, Length=497, Percent_Identity=29.9798792756539, Blast_Score=181, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6323822, Length=471, Percent_Identity=30.1486199575372, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324950, Length=457, Percent_Identity=26.0393873085339, Blast_Score=164, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6319478, Length=480, Percent_Identity=26.875, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6321828, Length=501, Percent_Identity=24.9500998003992, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323757, Length=325, Percent_Identity=23.6923076923077, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24668425, Length=466, Percent_Identity=30.9012875536481, Blast_Score=193, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24668417, Length=466, Percent_Identity=30.9012875536481, Blast_Score=193, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24668413, Length=466, Percent_Identity=30.9012875536481, Blast_Score=193, Evalue=6e-49,
Organism=Drosophila melanogaster, GI281362580, Length=444, Percent_Identity=29.5045045045045, Blast_Score=177, Evalue=5e-44,
Organism=Drosophila melanogaster, GI62472918, Length=444, Percent_Identity=29.5045045045045, Blast_Score=177, Evalue=5e-44,
Organism=Drosophila melanogaster, GI62472926, Length=444, Percent_Identity=29.5045045045045, Blast_Score=177, Evalue=5e-44,
Organism=Drosophila melanogaster, GI62472936, Length=444, Percent_Identity=29.5045045045045, Blast_Score=177, Evalue=5e-44,
Organism=Drosophila melanogaster, GI21356737, Length=444, Percent_Identity=29.5045045045045, Blast_Score=177, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24585660, Length=468, Percent_Identity=27.7777777777778, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24650465, Length=457, Percent_Identity=27.1334792122538, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI20129399, Length=454, Percent_Identity=27.5330396475771, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24666674, Length=479, Percent_Identity=27.5574112734864, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28571798, Length=472, Percent_Identity=26.271186440678, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28571796, Length=472, Percent_Identity=26.271186440678, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28571794, Length=472, Percent_Identity=26.271186440678, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28571802, Length=472, Percent_Identity=26.271186440678, Blast_Score=147, Evalue=4e-35,
Organism=Drosophila melanogaster, GI28571800, Length=472, Percent_Identity=26.271186440678, Blast_Score=147, Evalue=4e-35,
Organism=Drosophila melanogaster, GI28571806, Length=472, Percent_Identity=26.271186440678, Blast_Score=147, Evalue=5e-35,
Organism=Drosophila melanogaster, GI28574525, Length=456, Percent_Identity=25.6578947368421, Blast_Score=136, Evalue=9e-32,
Organism=Drosophila melanogaster, GI281360299, Length=402, Percent_Identity=26.1194029850746, Blast_Score=114, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281360297, Length=402, Percent_Identity=26.1194029850746, Blast_Score=114, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281360295, Length=402, Percent_Identity=26.1194029850746, Blast_Score=114, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24586250, Length=402, Percent_Identity=26.1194029850746, Blast_Score=114, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281360301, Length=402, Percent_Identity=26.1194029850746, Blast_Score=114, Evalue=5e-25,
Organism=Drosophila melanogaster, GI45552499, Length=402, Percent_Identity=25.8706467661692, Blast_Score=113, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24638876, Length=459, Percent_Identity=25.7080610021786, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281360303, Length=402, Percent_Identity=25.8706467661692, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24638878, Length=421, Percent_Identity=25.8907363420428, Blast_Score=111, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281360293, Length=167, Percent_Identity=29.3413173652695, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 132302; Mature: 132171

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTNIYPLLPSSAVLRENISRHYRIDEAELVQQLLIEAETETLQPEIKNLARKLIEKVRT
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
NRQKASGVDALMHEFSLSSQEGIALMCLAEALLRIPDQVTRDKLIKDKIAKGDWKSHIGN
CHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCC
SPSLFVNASAWGLVFTGKLLSLNQQALSSSLNQLISKAGEPVIRKGIDFAMRLLGKQFVT
CCCEEEECCCCCEEEECHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
GETIQLALKNSEARFNKGFRFTYDMLGESAFTEQDAQHYYQDYVNSIHAVGAASKGLGVY
CCEEEEEEECCCHHHCCCCEEEHHHHCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEE
HSSGVSVKLSAIHPRYSLAQYDRVMDELYPRLRDLFLLAKRYNIGLNIDAEEANRLEISL
ECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEH
DLIDRLLSEPELADFDGIGIVVQAYQKRCRSVIDYLIAKARENNRKLMIRLVKGAYWDSE
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEHHCCCCCCC
VKLAQTESASGYPVFTRKVHTDLNYVACAKKLLAAQDVVFPQFATHNAQTLATIYHLAKG
EEEEECCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHCC
KRFEFQCLHGMGETLYDQVVGKENLNIQCRVYAPVGSYQTLLAYLVRRLLENGSNSSFVN
CCEEEHHHHHCCHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHH
QIVDENVSIDKLLEDPVAKAGITAGTMHPKTPLPIKLFADRKNSAGYELSDMHHLVQLGA
HHHHCCCCHHHHHHCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
QLNALADHNQYRAVPQIAEQFYQGSQRKVIYNPADQTQIVGEVTYANETDVEKAFAIAEQ
HHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHC
NQTAWQATPAEQRAAILEKIADLMESNMPTLFDLAVREAGKTLNNAIAEVREAVDFCRYY
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANQVKRNPQAYQNPRGIIVAISPWNFPLAIFTGEVVSALVAGNVVLAKPAEQTSLMAHYA
HHHHHCCCHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHH
VELFYQAGVPKSVLQCLPGSGAEIGNKLTADPRVDGVIFTGSTETAKTINRNLQKHSKII
HHHHHHCCCCHHHHHHCCCCCHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCEE
PLIAETGGQNALIMDSSALGEQVVADVLNSAFDSAGQRCSALRVLYLQEDVADHILTMLK
EEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAMAELRVGKPQLLNTDIGPVIDRTAQSRLLAHIEKMKAVAKSYYQVPIAAEVEQNGIFV
HHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEC
PPTLLEIDHISQIEHEVFGPVLHVIRFNADRFEQIIDDINSTGFGLTSGLHSRIDATIDQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
WLDKVHAGNLYVNRNTVGAVVGVQPFGGMGLSGTGPKAGGPLYLQRLVKSEAWTLADLEG
HHHHHCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCC
EAVIETDKLAQAVRQTLTGEQQSEALALLQTLRQKSPLAQVYKMQGITGENNYLRFEARP
CEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEECCE
MIAVSNGSLFAQIKALIAIAVCGSKAVVKKDSPLAEYAHQFAEYLMVTDDFNNLSALSVM
EEEEECCCHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHEEEECCCCCHHHEEEE
IVLEPLSTQERQHYAECNGSILTYVESLELALSLLPLVHEKSISINTAAAGGNATLMSEM
EEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
D
C
>Mature Secondary Structure 
PTNIYPLLPSSAVLRENISRHYRIDEAELVQQLLIEAETETLQPEIKNLARKLIEKVRT
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
NRQKASGVDALMHEFSLSSQEGIALMCLAEALLRIPDQVTRDKLIKDKIAKGDWKSHIGN
CHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCC
SPSLFVNASAWGLVFTGKLLSLNQQALSSSLNQLISKAGEPVIRKGIDFAMRLLGKQFVT
CCCEEEECCCCCEEEECHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
GETIQLALKNSEARFNKGFRFTYDMLGESAFTEQDAQHYYQDYVNSIHAVGAASKGLGVY
CCEEEEEEECCCHHHCCCCEEEHHHHCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEE
HSSGVSVKLSAIHPRYSLAQYDRVMDELYPRLRDLFLLAKRYNIGLNIDAEEANRLEISL
ECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEH
DLIDRLLSEPELADFDGIGIVVQAYQKRCRSVIDYLIAKARENNRKLMIRLVKGAYWDSE
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEHHCCCCCCC
VKLAQTESASGYPVFTRKVHTDLNYVACAKKLLAAQDVVFPQFATHNAQTLATIYHLAKG
EEEEECCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHCC
KRFEFQCLHGMGETLYDQVVGKENLNIQCRVYAPVGSYQTLLAYLVRRLLENGSNSSFVN
CCEEEHHHHHCCHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHH
QIVDENVSIDKLLEDPVAKAGITAGTMHPKTPLPIKLFADRKNSAGYELSDMHHLVQLGA
HHHHCCCCHHHHHHCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
QLNALADHNQYRAVPQIAEQFYQGSQRKVIYNPADQTQIVGEVTYANETDVEKAFAIAEQ
HHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHC
NQTAWQATPAEQRAAILEKIADLMESNMPTLFDLAVREAGKTLNNAIAEVREAVDFCRYY
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANQVKRNPQAYQNPRGIIVAISPWNFPLAIFTGEVVSALVAGNVVLAKPAEQTSLMAHYA
HHHHHCCCHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHH
VELFYQAGVPKSVLQCLPGSGAEIGNKLTADPRVDGVIFTGSTETAKTINRNLQKHSKII
HHHHHHCCCCHHHHHHCCCCCHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCEE
PLIAETGGQNALIMDSSALGEQVVADVLNSAFDSAGQRCSALRVLYLQEDVADHILTMLK
EEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAMAELRVGKPQLLNTDIGPVIDRTAQSRLLAHIEKMKAVAKSYYQVPIAAEVEQNGIFV
HHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEC
PPTLLEIDHISQIEHEVFGPVLHVIRFNADRFEQIIDDINSTGFGLTSGLHSRIDATIDQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
WLDKVHAGNLYVNRNTVGAVVGVQPFGGMGLSGTGPKAGGPLYLQRLVKSEAWTLADLEG
HHHHHCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCC
EAVIETDKLAQAVRQTLTGEQQSEALALLQTLRQKSPLAQVYKMQGITGENNYLRFEARP
CEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEECCE
MIAVSNGSLFAQIKALIAIAVCGSKAVVKKDSPLAEYAHQFAEYLMVTDDFNNLSALSVM
EEEEECCCHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHEEEECCCCCHHHEEEE
IVLEPLSTQERQHYAECNGSILTYVESLELALSLLPLVHEKSISINTAAAGGNATLMSEM
EEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]