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The map label for this gene is trxB [H]

Identifier: 126207572

GI number: 126207572

Start: 92425

End: 93378

Strand: Direct

Name: trxB [H]

Synonym: APL_0084

Alternate gene names: 126207572

Gene position: 92425-93378 (Clockwise)

Preceding gene: 126207568

Following gene: 126207573

Centisome position: 4.06

GC content: 44.65

Gene sequence:

>954_bases
ATGACAGTTAAACACGCAAAACTTTTAATTTTAGGTTCAGGCCCGGCGGGCTATACCGCAGCCGTTTACGCCGCTCGTGC
GAATTTAAATCCGGTATTAGTTACAGGTATGCAACAAGGCGGTCAATTAACTACTACCGATGAAATTGAAAACTGGCCGG
GCGAGTATGAGCATACCACCGGTACCGGTTTAATGGATAAAATGCTGAAACACGCTGAAAAATTTAATACGGAAATCGTT
TTCGACCACATCAATAGCGTAGATTTATCAAAGCGTCCGTTTACTTTAAAAGGCGATATTAATACCTTTACCTGTGATGC
GTTAATTATCGCAACCGGCGCATCGGCAAAATATTTAGGTTTACCTTCTGAAGAAGCTTTTAAAGGCAAAGGCGTATCGG
CTTGCGCGACTTGTGACGGTTTCTTCTATCGTAACAAACCGGTTGCGGTTGTTGGCGGCGGTAATACTGCCGTTGAAGAA
GCGTTATATTTAGCCAATATTGCCAGTGAAGTGCATTTAGTACACCGCCGTGACAGCTTCCGTGCCGAGAAAATTTTATT
AGGCCGCTTACAGAAACGTGTGGAAGAAGGCAAAATTATTCTTCATACTGACAGAACGGTCGAAGAAGTGTTAGGCGATA
ATATGGGCGTAACCGGTGTGCGTTTAGCTTCAACCAAAGACGAGAGCAAAGAAGAAATTAAAGTGGATGGTTTCTTTGTC
GCAATCGGTCACGCACCGAATACTGCCATTTTTGACGGTCAGCTTGAATTGGATAACGGTTACATTAAAGTGAAATCGGG
CTTAGAAGGAAATGCGACCGCAACTAGCGTAGCAGGCGTATTTGCTGCCGGTGACGTTATGGATCATAACTATCGCCAAG
CAATCACTTCAGCAGGTACAGGCTGTATGGCAGCGTTAGACGCAGAACGCTTCCTAGATGCGTTAGAAGCCTAA

Upstream 100 bases:

>100_bases
TACTTCACAAAATCGAAAAAAAGATGAGTGAAAACGAAAATAGAGTTACAACTAAATTTACGCTAAAATAACAACAATAT
TTATTGATAAGGATTAAACA

Downstream 100 bases:

>100_bases
ATATTTTTACGGAACATTAGCTTCATTCAAACAAGCGGTTAAATTTCACAAGAATTTTGCCATGTTGATTTAAGCGGATG
TTCCGTGTTTTTTATAAAGG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTVKHAKLLILGSGPAGYTAAVYAARANLNPVLVTGMQQGGQLTTTDEIENWPGEYEHTTGTGLMDKMLKHAEKFNTEIV
FDHINSVDLSKRPFTLKGDINTFTCDALIIATGASAKYLGLPSEEAFKGKGVSACATCDGFFYRNKPVAVVGGGNTAVEE
ALYLANIASEVHLVHRRDSFRAEKILLGRLQKRVEEGKIILHTDRTVEEVLGDNMGVTGVRLASTKDESKEEIKVDGFFV
AIGHAPNTAIFDGQLELDNGYIKVKSGLEGNATATSVAGVFAAGDVMDHNYRQAITSAGTGCMAALDAERFLDALEA

Sequences:

>Translated_317_residues
MTVKHAKLLILGSGPAGYTAAVYAARANLNPVLVTGMQQGGQLTTTDEIENWPGEYEHTTGTGLMDKMLKHAEKFNTEIV
FDHINSVDLSKRPFTLKGDINTFTCDALIIATGASAKYLGLPSEEAFKGKGVSACATCDGFFYRNKPVAVVGGGNTAVEE
ALYLANIASEVHLVHRRDSFRAEKILLGRLQKRVEEGKIILHTDRTVEEVLGDNMGVTGVRLASTKDESKEEIKVDGFFV
AIGHAPNTAIFDGQLELDNGYIKVKSGLEGNATATSVAGVFAAGDVMDHNYRQAITSAGTGCMAALDAERFLDALEA
>Mature_316_residues
TVKHAKLLILGSGPAGYTAAVYAARANLNPVLVTGMQQGGQLTTTDEIENWPGEYEHTTGTGLMDKMLKHAEKFNTEIVF
DHINSVDLSKRPFTLKGDINTFTCDALIIATGASAKYLGLPSEEAFKGKGVSACATCDGFFYRNKPVAVVGGGNTAVEEA
LYLANIASEVHLVHRRDSFRAEKILLGRLQKRVEEGKIILHTDRTVEEVLGDNMGVTGVRLASTKDESKEEIKVDGFFVA
IGHAPNTAIFDGQLELDNGYIKVKSGLEGNATATSVAGVFAAGDVMDHNYRQAITSAGTGCMAALDAERFLDALEA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=76.1904761904762, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI87081763, Length=315, Percent_Identity=33.968253968254, Blast_Score=129, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320560, Length=325, Percent_Identity=48.6153846153846, Blast_Score=287, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6321898, Length=325, Percent_Identity=48, Blast_Score=284, Evalue=1e-77,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33916; Mature: 33785

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKHAKLLILGSGPAGYTAAVYAARANLNPVLVTGMQQGGQLTTTDEIENWPGEYEHTT
CCCCEEEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEHHHHHCCCCCCCCCC
GTGLMDKMLKHAEKFNTEIVFDHINSVDLSKRPFTLKGDINTFTCDALIIATGASAKYLG
CCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEEEECCCCEEEC
LPSEEAFKGKGVSACATCDGFFYRNKPVAVVGGGNTAVEEALYLANIASEVHLVHRRDSF
CCCCHHHCCCCCEEEEECCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHEEEECCCCH
RAEKILLGRLQKRVEEGKIILHTDRTVEEVLGDNMGVTGVRLASTKDESKEEIKVDGFFV
HHHHHHHHHHHHHHHCCCEEEECCCHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEEEE
AIGHAPNTAIFDGQLELDNGYIKVKSGLEGNATATSVAGVFAAGDVMDHNYRQAITSAGT
EEECCCCCEEEECEEEECCCEEEEECCCCCCCCHHHHHHHHEECCHHCCHHHHHHHHCCC
GCMAALDAERFLDALEA
CHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVKHAKLLILGSGPAGYTAAVYAARANLNPVLVTGMQQGGQLTTTDEIENWPGEYEHTT
CCCEEEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEHHHHHCCCCCCCCCC
GTGLMDKMLKHAEKFNTEIVFDHINSVDLSKRPFTLKGDINTFTCDALIIATGASAKYLG
CCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEEEECCCCEEEC
LPSEEAFKGKGVSACATCDGFFYRNKPVAVVGGGNTAVEEALYLANIASEVHLVHRRDSF
CCCCHHHCCCCCEEEEECCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHEEEECCCCH
RAEKILLGRLQKRVEEGKIILHTDRTVEEVLGDNMGVTGVRLASTKDESKEEIKVDGFFV
HHHHHHHHHHHHHHHCCCEEEECCCHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEEEE
AIGHAPNTAIFDGQLELDNGYIKVKSGLEGNATATSVAGVFAAGDVMDHNYRQAITSAGT
EEECCCCCEEEECEEEECCCEEEEECCCCCCCCHHHHHHHHEECCHHCCHHHHHHHHCCC
GCMAALDAERFLDALEA
CHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]