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The map label for this gene is argS [H]

Identifier: 126207527

GI number: 126207527

Start: 42435

End: 44081

Strand: Direct

Name: argS [H]

Synonym: APL_0039

Alternate gene names: 126207527

Gene position: 42435-44081 (Clockwise)

Preceding gene: 126207523

Following gene: 126207528

Centisome position: 1.87

GC content: 43.35

Gene sequence:

>1647_bases
GTGCGTCAATCGGGTAAACCGGAATTCGGCGATTATCAAGCAAACGGCGCAATGGGCGCAGCAAAAAAATTAGGTATGAA
CCCACGTGAGTTTGCCCAGAAAATTTTGGATAACGCAGATTTAAACGGCATTGCCGATAAATTAGAAATTGCCGGTCCGG
GCTTTATCAATATTTTCTTAAACCAAGCGTGGTTAGCAAATCAAGCAAGTGAAGCATTACAAGCGGTCAATTTCGGGATT
AAAACTGCAAATCCGCAAACGATCGTGATCGACTATTCTTCGCCGAACGTAGCGAAAGAAATGCACGTAGGTCACTTACG
TTCAACCATTATCGGTGATGCGGTGGTGCGTACTTTAGAATTTTTAGGTAATAAAGTGATTCGTGCCAACCACGTTGGCG
ACTGGGGTACGCAATTCGGTATGTTAATTGCTTACTTGGAGAAAATGGAAAACGAACACGCCAGCCAAATGGAATTAAGC
GATTTGGAAGCGTTCTACCGTGCGGCAAAAGAGCATTACGATAGTGATGAAGTATTTGCCGAAAAAGCACGTAACTATGT
GGTGAAACTCCAAAGCGGTGATGAATATTGCCGTACGATGTGGAAAAAATTAGTTGATATTACAATGCACCACAACCAAG
AAAACTACGATCGTTTAAACGTTACCCTTTCAGAAAAAGATGTGATGGGCGAAAGCCTTTACAACCCGATGTTGCCGGAA
ATCGTAGCGGATTTAAAAGCAAAAGGTTTAGCGGTGGAAGATGACGGTGCGTTGGTGGTGTTCTTAGAAGAATTTAAGAA
CAAAGACGGTGATCCGATGGGCGTTATCGTACAGAAAAAAGACGGCGGTTTCTTATATACCACGACGGATATTGCCGCAG
CGAAATATCGCTACGAAACCTTAAATGCGGATCGTGTGTTAGTGTTCTCGGATTCTCGCCAAGCACAACATATGCAACAA
GCGTGGTTAATTACTCGTAAAGCGGGTTATGTGCCGGAAAGTTTCAGCCTTGAACATCCGTTCTTCGGAATGATGTTAGG
CAAAGACGGCAAGCCGTTTAAAACCCGTTCGGGCGGTACGGTTAAATTAAAAGATCTATTAGATGAGGCGGTGGAACGTG
CGGATAAATTAATTTCAGAGCGTTCAACGGATTTAACCGCAGAAGAAAAAGCTGCGGTAGTGGAAGCTGTAGCTATCGGC
TCGGTCAAATATTCGGATCTCTCGAAAAACCGTACCACAGACTACGTATTCGACTGGGATAATATGCTGACCTTCGAAGG
CAACACCGCACCGTATATGCAGTACGCTTATACTCGTATTCGTTCAATCTTCAACCGTGCCGGCATTGATGTAAACGGCT
TAAACGGCGAAATTAATTTAACTGAAGATAAAGAGCGTGCGTTAGCGGTTAAACTTTTACAGTTTGAAGAAGCGTTAAAC
GGTGTAGCAAAAGACGGTATGCCGAATATTCTTTGCCAATACTTATACGAATTAGCCGGCGCATTCTCAAGTTTCTACGA
AGCTTGCCCGATGCTGAATGCGGAAGAGAATGTAAAAAACAGCCGTTTAAGTTTAGCCGCATTAACGGCGAAAACGCTAA
AACAAGGTCTAGATCTCTTAGGTATTAAGACGATTGAAAAAATGTAA

Upstream 100 bases:

>100_bases
TGAAAAAGGTTATAGATTCGTGAATATTCAACAGATTTTATCAGACAAAATTAAACAAGCAATGATTGCGGCAGGGGCGG
ACAGCAATATCGAGCCGCTA

Downstream 100 bases:

>100_bases
TGAAACGTCCCCCTCTTTTGTAAAGAGGGGTTAGGGGAGATTTTACAAGCGGTGAAATTTCTCCAATATTTTGCAAATTT
TAGATCTAACAAATCTCCCC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MRQSGKPEFGDYQANGAMGAAKKLGMNPREFAQKILDNADLNGIADKLEIAGPGFINIFLNQAWLANQASEALQAVNFGI
KTANPQTIVIDYSSPNVAKEMHVGHLRSTIIGDAVVRTLEFLGNKVIRANHVGDWGTQFGMLIAYLEKMENEHASQMELS
DLEAFYRAAKEHYDSDEVFAEKARNYVVKLQSGDEYCRTMWKKLVDITMHHNQENYDRLNVTLSEKDVMGESLYNPMLPE
IVADLKAKGLAVEDDGALVVFLEEFKNKDGDPMGVIVQKKDGGFLYTTTDIAAAKYRYETLNADRVLVFSDSRQAQHMQQ
AWLITRKAGYVPESFSLEHPFFGMMLGKDGKPFKTRSGGTVKLKDLLDEAVERADKLISERSTDLTAEEKAAVVEAVAIG
SVKYSDLSKNRTTDYVFDWDNMLTFEGNTAPYMQYAYTRIRSIFNRAGIDVNGLNGEINLTEDKERALAVKLLQFEEALN
GVAKDGMPNILCQYLYELAGAFSSFYEACPMLNAEENVKNSRLSLAALTAKTLKQGLDLLGIKTIEKM

Sequences:

>Translated_548_residues
MRQSGKPEFGDYQANGAMGAAKKLGMNPREFAQKILDNADLNGIADKLEIAGPGFINIFLNQAWLANQASEALQAVNFGI
KTANPQTIVIDYSSPNVAKEMHVGHLRSTIIGDAVVRTLEFLGNKVIRANHVGDWGTQFGMLIAYLEKMENEHASQMELS
DLEAFYRAAKEHYDSDEVFAEKARNYVVKLQSGDEYCRTMWKKLVDITMHHNQENYDRLNVTLSEKDVMGESLYNPMLPE
IVADLKAKGLAVEDDGALVVFLEEFKNKDGDPMGVIVQKKDGGFLYTTTDIAAAKYRYETLNADRVLVFSDSRQAQHMQQ
AWLITRKAGYVPESFSLEHPFFGMMLGKDGKPFKTRSGGTVKLKDLLDEAVERADKLISERSTDLTAEEKAAVVEAVAIG
SVKYSDLSKNRTTDYVFDWDNMLTFEGNTAPYMQYAYTRIRSIFNRAGIDVNGLNGEINLTEDKERALAVKLLQFEEALN
GVAKDGMPNILCQYLYELAGAFSSFYEACPMLNAEENVKNSRLSLAALTAKTLKQGLDLLGIKTIEKM
>Mature_548_residues
MRQSGKPEFGDYQANGAMGAAKKLGMNPREFAQKILDNADLNGIADKLEIAGPGFINIFLNQAWLANQASEALQAVNFGI
KTANPQTIVIDYSSPNVAKEMHVGHLRSTIIGDAVVRTLEFLGNKVIRANHVGDWGTQFGMLIAYLEKMENEHASQMELS
DLEAFYRAAKEHYDSDEVFAEKARNYVVKLQSGDEYCRTMWKKLVDITMHHNQENYDRLNVTLSEKDVMGESLYNPMLPE
IVADLKAKGLAVEDDGALVVFLEEFKNKDGDPMGVIVQKKDGGFLYTTTDIAAAKYRYETLNADRVLVFSDSRQAQHMQQ
AWLITRKAGYVPESFSLEHPFFGMMLGKDGKPFKTRSGGTVKLKDLLDEAVERADKLISERSTDLTAEEKAAVVEAVAIG
SVKYSDLSKNRTTDYVFDWDNMLTFEGNTAPYMQYAYTRIRSIFNRAGIDVNGLNGEINLTEDKERALAVKLLQFEEALN
GVAKDGMPNILCQYLYELAGAFSSFYEACPMLNAEENVKNSRLSLAALTAKTLKQGLDLLGIKTIEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=568, Percent_Identity=40.4929577464789, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI197100773, Length=474, Percent_Identity=31.2236286919831, Blast_Score=209, Evalue=6e-54,
Organism=Escherichia coli, GI1788184, Length=550, Percent_Identity=71.0909090909091, Blast_Score=822, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=572, Percent_Identity=40.2097902097902, Blast_Score=373, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI71985068, Length=536, Percent_Identity=41.044776119403, Blast_Score=359, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17532153, Length=488, Percent_Identity=26.6393442622951, Blast_Score=154, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320548, Length=544, Percent_Identity=32.3529411764706, Blast_Score=254, Evalue=3e-68,
Organism=Saccharomyces cerevisiae, GI6321883, Length=527, Percent_Identity=29.2220113851992, Blast_Score=226, Evalue=8e-60,
Organism=Drosophila melanogaster, GI18859963, Length=566, Percent_Identity=39.3992932862191, Blast_Score=393, Evalue=1e-109,
Organism=Drosophila melanogaster, GI28571570, Length=477, Percent_Identity=29.769392033543, Blast_Score=167, Evalue=1e-41,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 61153; Mature: 61153

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQSGKPEFGDYQANGAMGAAKKLGMNPREFAQKILDNADLNGIADKLEIAGPGFINIFL
CCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHEECCCCEEEEEE
NQAWLANQASEALQAVNFGIKTANPQTIVIDYSSPNVAKEMHVGHLRSTIIGDAVVRTLE
HHHHHHHHHHHHHHHHHCCEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FLGNKVIRANHVGDWGTQFGMLIAYLEKMENEHASQMELSDLEAFYRAAKEHYDSDEVFA
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EKARNYVVKLQSGDEYCRTMWKKLVDITMHHNQENYDRLNVTLSEKDVMGESLYNPMLPE
HHHCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHCCCHHHH
IVADLKAKGLAVEDDGALVVFLEEFKNKDGDPMGVIVQKKDGGFLYTTTDIAAAKYRYET
HHHHHHHCCEEEECCCEEEEEEHHHCCCCCCCEEEEEEECCCCEEEEECHHHHHHHHHEE
LNADRVLVFSDSRQAQHMQQAWLITRKAGYVPESFSLEHPFFGMMLGKDGKPFKTRSGGT
CCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCE
VKLKDLLDEAVERADKLISERSTDLTAEEKAAVVEAVAIGSVKYSDLSKNRTTDYVFDWD
EEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEECC
NMLTFEGNTAPYMQYAYTRIRSIFNRAGIDVNGLNGEINLTEDKERALAVKLLQFEEALN
CEEEECCCCCHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHH
GVAKDGMPNILCQYLYELAGAFSSFYEACPMLNAEENVKNSRLSLAALTAKTLKQGLDLL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHCCHHHH
GIKTIEKM
CHHHHHCC
>Mature Secondary Structure
MRQSGKPEFGDYQANGAMGAAKKLGMNPREFAQKILDNADLNGIADKLEIAGPGFINIFL
CCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHEECCCCEEEEEE
NQAWLANQASEALQAVNFGIKTANPQTIVIDYSSPNVAKEMHVGHLRSTIIGDAVVRTLE
HHHHHHHHHHHHHHHHHCCEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FLGNKVIRANHVGDWGTQFGMLIAYLEKMENEHASQMELSDLEAFYRAAKEHYDSDEVFA
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EKARNYVVKLQSGDEYCRTMWKKLVDITMHHNQENYDRLNVTLSEKDVMGESLYNPMLPE
HHHCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHCCCHHHH
IVADLKAKGLAVEDDGALVVFLEEFKNKDGDPMGVIVQKKDGGFLYTTTDIAAAKYRYET
HHHHHHHCCEEEECCCEEEEEEHHHCCCCCCCEEEEEEECCCCEEEEECHHHHHHHHHEE
LNADRVLVFSDSRQAQHMQQAWLITRKAGYVPESFSLEHPFFGMMLGKDGKPFKTRSGGT
CCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCE
VKLKDLLDEAVERADKLISERSTDLTAEEKAAVVEAVAIGSVKYSDLSKNRTTDYVFDWD
EEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCCCCCCCCCEEEECC
NMLTFEGNTAPYMQYAYTRIRSIFNRAGIDVNGLNGEINLTEDKERALAVKLLQFEEALN
CEEEECCCCCHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHH
GVAKDGMPNILCQYLYELAGAFSSFYEACPMLNAEENVKNSRLSLAALTAKTLKQGLDLL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHCCHHHH
GIKTIEKM
CHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA