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The map label for this gene is hlyB [H]

Identifier: 126175638

GI number: 126175638

Start: 4033836

End: 4035461

Strand: Direct

Name: hlyB [H]

Synonym: Sbal_3441

Alternate gene names: 126175638

Gene position: 4033836-4035461 (Clockwise)

Preceding gene: 126175637

Following gene: 126175640

Centisome position: 78.67

GC content: 48.03

Gene sequence:

>1626_bases
ATGTGGTTACGACAAATTAAGATTGGCTCACGACTCATTACTGCGTTTGGCTTACTCGGTCTAGTATTGTTACTTCAGGG
ACTTATGTCTCTGCAAACTATGTCATCCATGCGAGTCTCCTCAGAAGAAATTGAAAAAAATACCCTACCAACGCTCGTCA
CGCTATCGAGCATCAATCTTAACGTGATGCGCGCTAGGGTATTTACATTTCGTCTATTACTCGCCGATTCGGCGGCTGAG
CGCGACAAAGGGCTCGAAACCTTAAGGCAAATTCGCGAGAACATTAAAACGGATCAAAAGGCCTACGAGCCTTTAATTAG
TTTGCCTGGTGAGCAAGCCCTCTATCAGGATTTTAGTCATAATTTAGAGCTGTATTTACAGAATCAAGATCAAATGATCA
GTAAGCTGCAGGCCAATGACACGACTGAAGCTAAACGGATAATGGATGAAGTGATGACGTTACAAGCTGATAAAATAACT
AAAACGCTTATCAGCATTGGCGACTTAAATACCGAATATGCAGGCAAACAAGGCGAGATCACCGCACAAGCCTACGAGGA
AAGTAAGCTACTCAACAGCGTGGTGATAATAGCCTCCTTGATTGCCGCATTTGTTGTGGCCACACTCTTAACCCGCAGTA
TTGTGCAGCCGATGAAAGAAGCGGTAGATATTTCAGTGACGGTCGCAAGTGGTGATTTAACGCAGAAAATCCGTACAGAT
GGCAATGATGAAACCAGTCAGCTGATGCAGTCATTAGCAGGGATGCAGCAGAACCTGCGCGATACCTTATCCCACATCGC
AAACTCCTCTAACCAGCTCGCCTCCGCCGCCGAAGAACTCAATTCTGTGACTGAAGATGCTTCCCGCGGTATTCAGCAAC
AAAATGATGAAATACAACAGGCTGCAACCGCAATTACCGAGATGAGTTCGGCGGTGGATGAAGTCGCCAATACCGCAGTC
CTCGCTTCAGAGGCCTCAGAAGAAACCGCCCGCAATACTGAATTAGGTAAAAAACAGGTAGATCAAACCGTCGCCGCCAT
TATCGACATGAATCAGGATGTGACGCAAAGTTCGCAAATTGTCCAAACCTTAGCCATGCAAGCTGTCGATATTGGTAAAG
TTTTAGATGTGATCCGCGCGATTGCCGAGCAAACAAATTTACTGGCCCTCAATGCAGCCATTGAAGCGGCGCGAGCGGGC
GATACTGGCCGTGGTTTTGCGGTGGTTGCCGATGAAGTGCGCGCACTAGCCCACCGTACTCAGTCTTCGACCCGTGAAAT
TGAAGATATGATCAACAAGATCCAGCACGGCACCGAAACCGCTGTGCTATCGATGCAGCACAGTGGCCAAAAGGCAGAGC
AAGCACTCGCTGTCGCAAGGCTCGCTGGGGATGCATTGAACACGATCAACACTCAAATCAGTACGATGAATAACAGCAAT
ATGGTCATCGCAAGCGCCGCCGAAGAACAAGCGAAAGTCGCCCGTGAGGTTGATAAAAACATTGTTAACATTAGCGATCT
CGCCAGCCAAAGCGCCGCGGGAGCCCAGCAAACCAGTGCATCGGCACATGAACTATCAAGGTTAGCGGTTGAACTGAACA
ACCTACTGACGCGCTTTAAGGTGTAA

Upstream 100 bases:

>100_bases
CGAACTTTATGGCTCGACAGCAGTAGTTCGAAAGCATTAGTTTAAAAGCAGTAAGAACGACCTTAGACGGAACTAATTTA
AATACAGGGACGATTCGCTT

Downstream 100 bases:

>100_bases
AGTCGCCTGGTAAAGTCGTCTCGATTTAAGGTCAAAAGCCTCGCTTTTCGATTTGAGATCAAATCTCGTTTTACAAGGGA
ACCAGAGGGTAACGCACAAG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MWLRQIKIGSRLITAFGLLGLVLLLQGLMSLQTMSSMRVSSEEIEKNTLPTLVTLSSINLNVMRARVFTFRLLLADSAAE
RDKGLETLRQIRENIKTDQKAYEPLISLPGEQALYQDFSHNLELYLQNQDQMISKLQANDTTEAKRIMDEVMTLQADKIT
KTLISIGDLNTEYAGKQGEITAQAYEESKLLNSVVIIASLIAAFVVATLLTRSIVQPMKEAVDISVTVASGDLTQKIRTD
GNDETSQLMQSLAGMQQNLRDTLSHIANSSNQLASAAEELNSVTEDASRGIQQQNDEIQQAATAITEMSSAVDEVANTAV
LASEASEETARNTELGKKQVDQTVAAIIDMNQDVTQSSQIVQTLAMQAVDIGKVLDVIRAIAEQTNLLALNAAIEAARAG
DTGRGFAVVADEVRALAHRTQSSTREIEDMINKIQHGTETAVLSMQHSGQKAEQALAVARLAGDALNTINTQISTMNNSN
MVIASAAEEQAKVAREVDKNIVNISDLASQSAAGAQQTSASAHELSRLAVELNNLLTRFKV

Sequences:

>Translated_541_residues
MWLRQIKIGSRLITAFGLLGLVLLLQGLMSLQTMSSMRVSSEEIEKNTLPTLVTLSSINLNVMRARVFTFRLLLADSAAE
RDKGLETLRQIRENIKTDQKAYEPLISLPGEQALYQDFSHNLELYLQNQDQMISKLQANDTTEAKRIMDEVMTLQADKIT
KTLISIGDLNTEYAGKQGEITAQAYEESKLLNSVVIIASLIAAFVVATLLTRSIVQPMKEAVDISVTVASGDLTQKIRTD
GNDETSQLMQSLAGMQQNLRDTLSHIANSSNQLASAAEELNSVTEDASRGIQQQNDEIQQAATAITEMSSAVDEVANTAV
LASEASEETARNTELGKKQVDQTVAAIIDMNQDVTQSSQIVQTLAMQAVDIGKVLDVIRAIAEQTNLLALNAAIEAARAG
DTGRGFAVVADEVRALAHRTQSSTREIEDMINKIQHGTETAVLSMQHSGQKAEQALAVARLAGDALNTINTQISTMNNSN
MVIASAAEEQAKVAREVDKNIVNISDLASQSAAGAQQTSASAHELSRLAVELNNLLTRFKV
>Mature_541_residues
MWLRQIKIGSRLITAFGLLGLVLLLQGLMSLQTMSSMRVSSEEIEKNTLPTLVTLSSINLNVMRARVFTFRLLLADSAAE
RDKGLETLRQIRENIKTDQKAYEPLISLPGEQALYQDFSHNLELYLQNQDQMISKLQANDTTEAKRIMDEVMTLQADKIT
KTLISIGDLNTEYAGKQGEITAQAYEESKLLNSVVIIASLIAAFVVATLLTRSIVQPMKEAVDISVTVASGDLTQKIRTD
GNDETSQLMQSLAGMQQNLRDTLSHIANSSNQLASAAEELNSVTEDASRGIQQQNDEIQQAATAITEMSSAVDEVANTAV
LASEASEETARNTELGKKQVDQTVAAIIDMNQDVTQSSQIVQTLAMQAVDIGKVLDVIRAIAEQTNLLALNAAIEAARAG
DTGRGFAVVADEVRALAHRTQSSTREIEDMINKIQHGTETAVLSMQHSGQKAEQALAVARLAGDALNTINTQISTMNNSN
MVIASAAEEQAKVAREVDKNIVNISDLASQSAAGAQQTSASAHELSRLAVELNNLLTRFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=354, Percent_Identity=30.7909604519774, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1787690, Length=550, Percent_Identity=25.4545454545455, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788194, Length=360, Percent_Identity=30, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788195, Length=302, Percent_Identity=28.8079470198675, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1789453, Length=258, Percent_Identity=30.6201550387597, Blast_Score=93, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58609; Mature: 58609

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLRQIKIGSRLITAFGLLGLVLLLQGLMSLQTMSSMRVSSEEIEKNTLPTLVTLSSINL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCH
NVMRARVFTFRLLLADSAAERDKGLETLRQIRENIKTDQKAYEPLISLPGEQALYQDFSH
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCC
NLELYLQNQDQMISKLQANDTTEAKRIMDEVMTLQADKITKTLISIGDLNTEYAGKQGEI
CEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TAQAYEESKLLNSVVIIASLIAAFVVATLLTRSIVQPMKEAVDISVTVASGDLTQKIRTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHCC
GNDETSQLMQSLAGMQQNLRDTLSHIANSSNQLASAAEELNSVTEDASRGIQQQNDEIQQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
AATAITEMSSAVDEVANTAVLASEASEETARNTELGKKQVDQTVAAIIDMNQDVTQSSQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VQTLAMQAVDIGKVLDVIRAIAEQTNLLALNAAIEAARAGDTGRGFAVVADEVRALAHRT
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
QSSTREIEDMINKIQHGTETAVLSMQHSGQKAEQALAVARLAGDALNTINTQISTMNNSN
HHHHHHHHHHHHHHHCCCHHHHEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
MVIASAAEEQAKVAREVDKNIVNISDLASQSAAGAQQTSASAHELSRLAVELNNLLTRFK
EEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHHC
V
C
>Mature Secondary Structure
MWLRQIKIGSRLITAFGLLGLVLLLQGLMSLQTMSSMRVSSEEIEKNTLPTLVTLSSINL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCH
NVMRARVFTFRLLLADSAAERDKGLETLRQIRENIKTDQKAYEPLISLPGEQALYQDFSH
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCC
NLELYLQNQDQMISKLQANDTTEAKRIMDEVMTLQADKITKTLISIGDLNTEYAGKQGEI
CEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TAQAYEESKLLNSVVIIASLIAAFVVATLLTRSIVQPMKEAVDISVTVASGDLTQKIRTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHCC
GNDETSQLMQSLAGMQQNLRDTLSHIANSSNQLASAAEELNSVTEDASRGIQQQNDEIQQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
AATAITEMSSAVDEVANTAVLASEASEETARNTELGKKQVDQTVAAIIDMNQDVTQSSQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VQTLAMQAVDIGKVLDVIRAIAEQTNLLALNAAIEAARAGDTGRGFAVVADEVRALAHRT
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
QSSTREIEDMINKIQHGTETAVLSMQHSGQKAEQALAVARLAGDALNTINTQISTMNNSN
HHHHHHHHHHHHHHHCCCHHHHEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
MVIASAAEEQAKVAREVDKNIVNISDLASQSAAGAQQTSASAHELSRLAVELNNLLTRFK
EEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHHC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]