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The map label for this gene is pntB [H]

Identifier: 126175615

GI number: 126175615

Start: 4007260

End: 4008744

Strand: Direct

Name: pntB [H]

Synonym: Sbal_3418

Alternate gene names: 126175615

Gene position: 4007260-4008744 (Clockwise)

Preceding gene: 126175614

Following gene: 126175616

Centisome position: 78.15

GC content: 50.17

Gene sequence:

>1485_bases
GTGTCTCAAGGACTGGTAACAGCAGCTTACATTATTGCCGCCATTCTCTTCATCTTCAGTCTCGCGGGACTGTCGAAGCA
AGAGACGGCAAAACACGGCAATTTATTCGGTATCTTAGGTATGGCAATCGCCCTACTGGCTACCATTTTCAACCCTGATA
CTAACGGTATTGCGTGGATCTTAATCGCCATGGTGATTGGCGGCGCGATTGGTATCCGTTTAGCATTAAAAGTCGAAATG
ACTGAAATGCCTGAACTGGTTGCCATCTTGCACAGTTTTGTTGGTATGGCCGCGGTATTGGTTGGCTTTAACAGCTTTAT
CGACTTACACCCACAGGAAGTGTCGCAAGTAGTCGTAGCTGTCGGTGGCGATATTAATACGACCCTCGCCGCTGTGCACG
ATGCCCTCAGCGAAGCGGCCAAAGCCGCCAGCAAAGAACATCTCACTGGCGCCATGCTTAACATTCACTTGGTCGAAGTT
TTCCTCGGGATCTTCATCGGTGCGGTCACCTTCACAGGTTCTATCGTGGCCTTTTGTAAGTTACGCGGCGTGATTTCATC
TAAACCTTTGATGCTGCCACATCGCCACAAGTTGAACCTAGTGGCAGTGCTCGTGTCTTTCGCCCTGTTGGTGTACTTCG
TCCAAACTGGCGGCACTATACCAGCACTGCTATTGATGACCTTGATTGCCTTCGCCTTTGGCTGGCATTTAGTCGCATCG
ATTGGCGGCGCAGATATGCCAGTGGTGGTGTCTATGCTTAACTCCTACTCAGGTTGGGCAGCGGCGGCAGCGGGCTTTAT
GTTGTCAAACGACCTCTTGATTGTCGTTGGCGCATTAGTGGGTTCATCGGGTGCAATTCTGTCTTACATAATGTGTAAGG
CGATGAATCGCTCGTTTATTTCTGTAATAGCTGGTGGCTTTGGCACAGATGGTGTGGCCTCGACTGCCGATGAAGAAATG
GGCGAATACCGTGAAACCAACGCTGAAGATGTGGCGGATATGCTGAAAAATGCCACCTCTGTCATCATCACCCCAGGTTA
CGGCATGGCTGTGGCACAGGCGCAATATCCTGTCGCTGAAATCACCAAAAGACTGCGCGATCTTGGCGTGAAAGTCCGTT
TCGGCATCCACCCAGTTGCAGGCCGTTTACCCGGTCATATGAACGTACTGCTAGCTGAAGCGAAAGTCCCCTACGATATC
GTGCTTGAAATGGACGAAATCAACGACGACTTTAACGACACTGACGTAGTACTAGTAATTGGTGCGAACGACACGGTTAA
CCCTGCGGCAATGGAAGATCCAGGTAGCCCAATCGCAGGCATGCCAGTGCTCGAAGTGTGGAAAGCGCAAAACGTTATCG
GCTTTAAACGCTCGATGAACACAGGTTATGCCGGCGTGCAAAACCCACTGTTCTTCAAAGATAATACCCAAATGCTATTT
GGGGATGCGAAGGCCAGTGTCGAAGCGATTTTAAAAGCGCTTTGA

Upstream 100 bases:

>100_bases
CGTTTATCGCCGTGCTGATCGCCAGTATTAACATCTTCGGTGGCTTTACCGTCACTCAGCGCATGCTGAAGATGTTCCGT
AAGGATTAAGGGGGTTTAAC

Downstream 100 bases:

>100_bases
GTCTGATGTAACCTTTACAGAGTGGCAATCGTTTAGGTGAAACACACTGTTTCAATGATAAAAAGGGAGCCGCTGGCTCC
CTTTTCATTTCACATTTTTT

Product: pyridine nucleotide transhydrogenase

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Pyridine nucleotide transhydrogenase subunit beta [H]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSQGLVTAAYIIAAILFIFSLAGLSKQETAKHGNLFGILGMAIALLATIFNPDTNGIAWILIAMVIGGAIGIRLALKVEM
TEMPELVAILHSFVGMAAVLVGFNSFIDLHPQEVSQVVVAVGGDINTTLAAVHDALSEAAKAASKEHLTGAMLNIHLVEV
FLGIFIGAVTFTGSIVAFCKLRGVISSKPLMLPHRHKLNLVAVLVSFALLVYFVQTGGTIPALLLMTLIAFAFGWHLVAS
IGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVVGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGVASTADEEM
GEYRETNAEDVADMLKNATSVIITPGYGMAVAQAQYPVAEITKRLRDLGVKVRFGIHPVAGRLPGHMNVLLAEAKVPYDI
VLEMDEINDDFNDTDVVLVIGANDTVNPAAMEDPGSPIAGMPVLEVWKAQNVIGFKRSMNTGYAGVQNPLFFKDNTQMLF
GDAKASVEAILKAL

Sequences:

>Translated_494_residues
MSQGLVTAAYIIAAILFIFSLAGLSKQETAKHGNLFGILGMAIALLATIFNPDTNGIAWILIAMVIGGAIGIRLALKVEM
TEMPELVAILHSFVGMAAVLVGFNSFIDLHPQEVSQVVVAVGGDINTTLAAVHDALSEAAKAASKEHLTGAMLNIHLVEV
FLGIFIGAVTFTGSIVAFCKLRGVISSKPLMLPHRHKLNLVAVLVSFALLVYFVQTGGTIPALLLMTLIAFAFGWHLVAS
IGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVVGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGVASTADEEM
GEYRETNAEDVADMLKNATSVIITPGYGMAVAQAQYPVAEITKRLRDLGVKVRFGIHPVAGRLPGHMNVLLAEAKVPYDI
VLEMDEINDDFNDTDVVLVIGANDTVNPAAMEDPGSPIAGMPVLEVWKAQNVIGFKRSMNTGYAGVQNPLFFKDNTQMLF
GDAKASVEAILKAL
>Mature_493_residues
SQGLVTAAYIIAAILFIFSLAGLSKQETAKHGNLFGILGMAIALLATIFNPDTNGIAWILIAMVIGGAIGIRLALKVEMT
EMPELVAILHSFVGMAAVLVGFNSFIDLHPQEVSQVVVAVGGDINTTLAAVHDALSEAAKAASKEHLTGAMLNIHLVEVF
LGIFIGAVTFTGSIVAFCKLRGVISSKPLMLPHRHKLNLVAVLVSFALLVYFVQTGGTIPALLLMTLIAFAFGWHLVASI
GGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVVGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGVASTADEEMG
EYRETNAEDVADMLKNATSVIITPGYGMAVAQAQYPVAEITKRLRDLGVKVRFGIHPVAGRLPGHMNVLLAEAKVPYDIV
LEMDEINDDFNDTDVVLVIGANDTVNPAAMEDPGSPIAGMPVLEVWKAQNVIGFKRSMNTGYAGVQNPLFFKDNTQMLFG
DAKASVEAILKAL

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=489, Percent_Identity=49.2842535787321, Blast_Score=445, Evalue=1e-125,
Organism=Homo sapiens, GI122939153, Length=489, Percent_Identity=49.2842535787321, Blast_Score=445, Evalue=1e-125,
Organism=Escherichia coli, GI1787886, Length=497, Percent_Identity=76.4587525150905, Blast_Score=736, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17550456, Length=491, Percent_Identity=48.6761710794297, Blast_Score=413, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 52081; Mature: 51950

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHC
>Mature Secondary Structure 
SQGLVTAAYIIAAILFIFSLAGLSKQETAKHGNLFGILGMAIALLATIFNPDTNGIAWI
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHH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CCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]