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The map label for this gene is kinE [H]

Identifier: 126175601

GI number: 126175601

Start: 3986199

End: 3988097

Strand: Direct

Name: kinE [H]

Synonym: Sbal_3404

Alternate gene names: 126175601

Gene position: 3986199-3988097 (Clockwise)

Preceding gene: 126175600

Following gene: 126175607

Centisome position: 77.74

GC content: 46.71

Gene sequence:

>1899_bases
ATGACAGCGCCATCGCAATTGACTCAGCCTACCTTCTGGGGCTACTGGCTCAGATTCATGCTGCCGTGGTTATTGTTGGT
GCCCATACTCACCACTTTGCTTTATCAAAAGCGCCATGAAGATGCCATGGTGCCCTTATACCAAGAGGCGAACACCCTTT
TAGGTGATGCCGCTAAAACCATTGCCTACCATATTGGTAATATTAAGCGCGACGCCCTATTTCTTGCTAAATATCAAGCA
CTCCTCGATGCGGCAGCGGGAAATGAGCAAGATCTCACTCAGGTCGAACATTTCTTCGAGAGCTTTAGTGCCGCATCACA
AAACTACGATCAAGTACGTTGGCTCGATAATAACGCCTTAGAAAAAGTCAGAGTCAATCTTGTCCAGAATCTCCCACACA
TAGTTGCTAAACCATTATTACAATTGAAGGCTAAGCGATATTACGCCATCCAGAGTTTAAGCTTAGCCCCTAATAGTTTT
TACTTTTCGCCCTTAGATTTGAATGTCGAAAAGGGAGAAATAGAAAATCCAATCAAGCCCGTATTAAGAGTCACCACTCC
CGTGTTTTTACCTTCGGGCGAGCGCCAAGGCTTTATTGCCCTCAATTTTCTCGCCCAATCCATGTTAGACGCCATTGCCA
AAATTACGGCTAACAGCAATGTCGAGCTTTCACTGCTGAATAAAGAGGGTTACTGGCTACTCTCATCCAATCCCGAACTC
ACCTGGGCATTTATGTTTAATCGCCCGGAATTAACCTTAGCTAAGCTCAATCCCGATGCTTGGCAACAGATTACCCAAGA
TAGCGAAGGCGCCTTTATTACCCCCGAAGGGCTCTGGGATTATGAAAATGTACAAGATGCGACCAACACTTCTGACCAAG
ATTGGAAACTCGTGATACGGGTTCCCAATGATCAACTCTCAAAGATTAATCAACGCAGCCTGCTGGAAGCGCTCAGTCTA
GGGATTTTATTACTGTTACTCGGCGGTGGGATCTGTTGGCGCGCTGCAAAGTCCATGCGAGAACGGGACAAATTGAATCA
AGAGTTAACCGAGCAACAGCAAAAACTCACCCAATCCAATGCCGCGTTAGCCGAATCGTTACAGCACTTACACGACACTC
AGCAACAACTCATCGAGACGGGAAAACTCTCATCCTTAGGCATGATGGTGGCTGGCGTCGCCCATGAACTCAATACCCCA
GTCGGCGCTGCACAGGTCACGTTATCGAGCATGAAAAATGAATGCACTAAGTTGCAAACCGCCTTCGAAACGGGTCTTAA
GCGATCTGATGTTGATACTTACTTTATTCACTTCCATGAAGGCGCGGAGATAGTGCAAGCCAACTTAAGCAGAGCCGCAA
CCTTAGTCAGTAGTTTCAAACGCTTAGCCGTCGATAGAACAAGGGAAGAGCGCCGTAGTTTTAAGCTCACGAGCCTCGTT
CAGGACATGCTACATACCTCATGGCTGCGGATGAAGAAGCAATCCCATGAGCTCGAAATCGACGTTGATGCCAATATCGA
ACTGAACAGCTACCCTGGCGCACTCGGACAATCCCTTGAAAACCTCGTCACCAATGCGATAACTCACGCTTTTGAAGGGC
GAGTTAATGGTCAAATCAAAATCTCGGCAAAGATGATAGAAGAGCAAATAGTCGAAATCACAGTCTCAGACAATGGCATA
GGAATGAGCGAGGAAACAATGAAACAAATCTTCGATCCCTTCTTTACCACTCGTAGGGGAAATGGCGGAACTGGGCTGGG
TTTACACTTAACCTATCAACTTGTTAGCCAACTTCTTGGCGGGAAAATTACGGTCAGCAGTACGTTAGGTAAAGGCAGCG
TTTTTAGTCTAACAATCCCAGTAACAGCCCCAGAAGCCGCCGAGCTGAATCTGAATTAA

Upstream 100 bases:

>100_bases
GCGACCGCGGCTGCCACGATGCCCAAGGCTACTTTTATGCTAAGCCAATGCCACTACCGGAGTTATTAACTTGGCTTAAA
AACTACCAAAAAACACCACT

Downstream 100 bases:

>100_bases
CCGGTTATACGCAACGGCGATAGATGGCCAATATGCTGGCCGAATATGATGCTAAAACTTGATGTCTAAACATGATGCTT
GAACTATGGTGTTTGAATAT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Sensor histidine kinase E [H]

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MTAPSQLTQPTFWGYWLRFMLPWLLLVPILTTLLYQKRHEDAMVPLYQEANTLLGDAAKTIAYHIGNIKRDALFLAKYQA
LLDAAAGNEQDLTQVEHFFESFSAASQNYDQVRWLDNNALEKVRVNLVQNLPHIVAKPLLQLKAKRYYAIQSLSLAPNSF
YFSPLDLNVEKGEIENPIKPVLRVTTPVFLPSGERQGFIALNFLAQSMLDAIAKITANSNVELSLLNKEGYWLLSSNPEL
TWAFMFNRPELTLAKLNPDAWQQITQDSEGAFITPEGLWDYENVQDATNTSDQDWKLVIRVPNDQLSKINQRSLLEALSL
GILLLLLGGGICWRAAKSMRERDKLNQELTEQQQKLTQSNAALAESLQHLHDTQQQLIETGKLSSLGMMVAGVAHELNTP
VGAAQVTLSSMKNECTKLQTAFETGLKRSDVDTYFIHFHEGAEIVQANLSRAATLVSSFKRLAVDRTREERRSFKLTSLV
QDMLHTSWLRMKKQSHELEIDVDANIELNSYPGALGQSLENLVTNAITHAFEGRVNGQIKISAKMIEEQIVEITVSDNGI
GMSEETMKQIFDPFFTTRRGNGGTGLGLHLTYQLVSQLLGGKITVSSTLGKGSVFSLTIPVTAPEAAELNLN

Sequences:

>Translated_632_residues
MTAPSQLTQPTFWGYWLRFMLPWLLLVPILTTLLYQKRHEDAMVPLYQEANTLLGDAAKTIAYHIGNIKRDALFLAKYQA
LLDAAAGNEQDLTQVEHFFESFSAASQNYDQVRWLDNNALEKVRVNLVQNLPHIVAKPLLQLKAKRYYAIQSLSLAPNSF
YFSPLDLNVEKGEIENPIKPVLRVTTPVFLPSGERQGFIALNFLAQSMLDAIAKITANSNVELSLLNKEGYWLLSSNPEL
TWAFMFNRPELTLAKLNPDAWQQITQDSEGAFITPEGLWDYENVQDATNTSDQDWKLVIRVPNDQLSKINQRSLLEALSL
GILLLLLGGGICWRAAKSMRERDKLNQELTEQQQKLTQSNAALAESLQHLHDTQQQLIETGKLSSLGMMVAGVAHELNTP
VGAAQVTLSSMKNECTKLQTAFETGLKRSDVDTYFIHFHEGAEIVQANLSRAATLVSSFKRLAVDRTREERRSFKLTSLV
QDMLHTSWLRMKKQSHELEIDVDANIELNSYPGALGQSLENLVTNAITHAFEGRVNGQIKISAKMIEEQIVEITVSDNGI
GMSEETMKQIFDPFFTTRRGNGGTGLGLHLTYQLVSQLLGGKITVSSTLGKGSVFSLTIPVTAPEAAELNLN
>Mature_631_residues
TAPSQLTQPTFWGYWLRFMLPWLLLVPILTTLLYQKRHEDAMVPLYQEANTLLGDAAKTIAYHIGNIKRDALFLAKYQAL
LDAAAGNEQDLTQVEHFFESFSAASQNYDQVRWLDNNALEKVRVNLVQNLPHIVAKPLLQLKAKRYYAIQSLSLAPNSFY
FSPLDLNVEKGEIENPIKPVLRVTTPVFLPSGERQGFIALNFLAQSMLDAIAKITANSNVELSLLNKEGYWLLSSNPELT
WAFMFNRPELTLAKLNPDAWQQITQDSEGAFITPEGLWDYENVQDATNTSDQDWKLVIRVPNDQLSKINQRSLLEALSLG
ILLLLLGGGICWRAAKSMRERDKLNQELTEQQQKLTQSNAALAESLQHLHDTQQQLIETGKLSSLGMMVAGVAHELNTPV
GAAQVTLSSMKNECTKLQTAFETGLKRSDVDTYFIHFHEGAEIVQANLSRAATLVSSFKRLAVDRTREERRSFKLTSLVQ
DMLHTSWLRMKKQSHELEIDVDANIELNSYPGALGQSLENLVTNAITHAFEGRVNGQIKISAKMIEEQIVEITVSDNGIG
MSEETMKQIFDPFFTTRRGNGGTGLGLHLTYQLVSQLLGGKITVSSTLGKGSVFSLTIPVTAPEAAELNLN

Specific function: Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=251, Percent_Identity=31.0756972111554, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788549, Length=252, Percent_Identity=28.1746031746032, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=255, Percent_Identity=27.843137254902, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI145693157, Length=271, Percent_Identity=26.5682656826568, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789149, Length=279, Percent_Identity=25.8064516129032, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70604; Mature: 70472

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPSQLTQPTFWGYWLRFMLPWLLLVPILTTLLYQKRHEDAMVPLYQEANTLLGDAAKT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IAYHIGNIKRDALFLAKYQALLDAAAGNEQDLTQVEHFFESFSAASQNYDQVRWLDNNAL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHH
EKVRVNLVQNLPHIVAKPLLQLKAKRYYAIQSLSLAPNSFYFSPLDLNVEKGEIENPIKP
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCEECCCCCCCCCCHHHH
VLRVTTPVFLPSGERQGFIALNFLAQSMLDAIAKITANSNVELSLLNKEGYWLLSSNPEL
HHHHHCCEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCE
TWAFMFNRPELTLAKLNPDAWQQITQDSEGAFITPEGLWDYENVQDATNTSDQDWKLVIR
EEEEEECCCCEEEEECCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEE
VPNDQLSKINQRSLLEALSLGILLLLLGGGICWRAAKSMRERDKLNQELTEQQQKLTQSN
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALAESLQHLHDTQQQLIETGKLSSLGMMVAGVAHELNTPVGAAQVTLSSMKNECTKLQT
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AFETGLKRSDVDTYFIHFHEGAEIVQANLSRAATLVSSFKRLAVDRTREERRSFKLTSLV
HHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDMLHTSWLRMKKQSHELEIDVDANIELNSYPGALGQSLENLVTNAITHAFEGRVNGQIK
HHHHHHHHHHHHHCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
ISAKMIEEQIVEITVSDNGIGMSEETMKQIFDPFFTTRRGNGGTGLGLHLTYQLVSQLLG
EHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
GKITVSSTLGKGSVFSLTIPVTAPEAAELNLN
CEEEEEECCCCCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TAPSQLTQPTFWGYWLRFMLPWLLLVPILTTLLYQKRHEDAMVPLYQEANTLLGDAAKT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IAYHIGNIKRDALFLAKYQALLDAAAGNEQDLTQVEHFFESFSAASQNYDQVRWLDNNAL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHH
EKVRVNLVQNLPHIVAKPLLQLKAKRYYAIQSLSLAPNSFYFSPLDLNVEKGEIENPIKP
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCEECCCCCCCCCCHHHH
VLRVTTPVFLPSGERQGFIALNFLAQSMLDAIAKITANSNVELSLLNKEGYWLLSSNPEL
HHHHHCCEEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCE
TWAFMFNRPELTLAKLNPDAWQQITQDSEGAFITPEGLWDYENVQDATNTSDQDWKLVIR
EEEEEECCCCEEEEECCHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEE
VPNDQLSKINQRSLLEALSLGILLLLLGGGICWRAAKSMRERDKLNQELTEQQQKLTQSN
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALAESLQHLHDTQQQLIETGKLSSLGMMVAGVAHELNTPVGAAQVTLSSMKNECTKLQT
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AFETGLKRSDVDTYFIHFHEGAEIVQANLSRAATLVSSFKRLAVDRTREERRSFKLTSLV
HHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDMLHTSWLRMKKQSHELEIDVDANIELNSYPGALGQSLENLVTNAITHAFEGRVNGQIK
HHHHHHHHHHHHHCCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
ISAKMIEEQIVEITVSDNGIGMSEETMKQIFDPFFTTRRGNGGTGLGLHLTYQLVSQLLG
EHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
GKITVSSTLGKGSVFSLTIPVTAPEAAELNLN
CEEEEEECCCCCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]