Click here to switch to the map view.

The map label for this gene is mlrA [H]

Identifier: 126175257

GI number: 126175257

Start: 3576934

End: 3577962

Strand: Reverse

Name: mlrA [H]

Synonym: Sbal_3055

Alternate gene names: 126175257

Gene position: 3577962-3576934 (Counterclockwise)

Preceding gene: 126175258

Following gene: 126175256

Centisome position: 69.78

GC content: 48.3

Gene sequence:

>1029_bases
ATGAAACAAGATACCCAGTCCATAACCAACGATGAGCCCAATGATGGCGTGTTACTCCCCATTGGTGAAGTGTCGGCCTT
AACGGGCGTGAATGCTGTGACCTTAAGGGCATGGCAGCGCCGTTTTGGTTTAGTGATCCCTGCGCGCACGCCCAAGGGAC
ACAGATTATATACGAGTAAAAATATCCAAGAAATCCACGAGATTAATGCATGGTTAGCTAAAGGTGTTGCGATCAGCAAG
GTTAAACCTTTGCTGATGAGTGCCGCCAAATTATCAAGTGAAATGATTGAATCCCAAGTTGTCGATCTGTGGGGCGAGCA
AATTATTGCGCTGAATGCAGCATTGTTCGACTTCAATCAGCATAAATTGCAGCAGATATTAGACGATGCATTTGGCTTAT
ATCCGTTTCAATTACTAAAAGAAAAGTTACTGCAACCTTGGCTTAATCAACTCGAAGACTTAGTGGATGAGCGGCTCGAT
GCCGAGTTAATTCTCGCTTGGTTAAAAAGCGAATTACTCAGCCGAGTAGGCGGGCGTTATGCCTTTACCGGACAGGCCGT
TGCGGCGCGAATGGCTGTGGTGCAGTTATCCCGCGGCGCGGCCACGCCGCCTAATTCTGCCCGTACTAAAAGTCTGTTTT
CTTTGCTGCTATCGCTCGAGTTAGCGTCGCTTCGAGTATCGGTAATCGACCTTGGCGAGCAGGCCATAGGCAGTTTACCG
CTGCTGCAGGGCAGACTTAACGTCGATGCACTTTTGCTGATCCCTGATCCAAATCATTCGGGGTCTGAGCAGACTGAAAT
GCTCACAGTATTGGCACAAATGAGTTTCCCATGCCGATTTGTTGGCCCCTTTGCGCCGACGTTGATTTCCTTATCGGCTT
TCTGGGCGCCTTCGATGACAGACTTGATTGGACAAATACCGTCTCGCTCCATGGGTAAGGTCAACATAAGTCACAAAGGC
AAAGGGAAAAGTATTGGCGTGAGTCAAAGCGAGCAGGGCAATAGTGGAGAAAACAATGACATCAGTTAA

Upstream 100 bases:

>100_bases
ATCCTCATCCAGAGGCGTTGAAGCTGCGCTATGCCTATTAGTATTTTTTTGCCGTACTGAGTAGTTTTTAGCTTTGAATT
TAGTGAGTTATTACTGATAT

Downstream 100 bases:

>100_bases
CGATTCAATGGCAATAGATTCAATGCCAATAGATTCAATGTCAATAAAAGTGCAGGGCAATAATGCATTGATGTGGTTTC
GCCAAGATTTACGCCTTGCC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: MerR-like regulator A [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKQDTQSITNDEPNDGVLLPIGEVSALTGVNAVTLRAWQRRFGLVIPARTPKGHRLYTSKNIQEIHEINAWLAKGVAISK
VKPLLMSAAKLSSEMIESQVVDLWGEQIIALNAALFDFNQHKLQQILDDAFGLYPFQLLKEKLLQPWLNQLEDLVDERLD
AELILAWLKSELLSRVGGRYAFTGQAVAARMAVVQLSRGAATPPNSARTKSLFSLLLSLELASLRVSVIDLGEQAIGSLP
LLQGRLNVDALLLIPDPNHSGSEQTEMLTVLAQMSFPCRFVGPFAPTLISLSAFWAPSMTDLIGQIPSRSMGKVNISHKG
KGKSIGVSQSEQGNSGENNDIS

Sequences:

>Translated_342_residues
MKQDTQSITNDEPNDGVLLPIGEVSALTGVNAVTLRAWQRRFGLVIPARTPKGHRLYTSKNIQEIHEINAWLAKGVAISK
VKPLLMSAAKLSSEMIESQVVDLWGEQIIALNAALFDFNQHKLQQILDDAFGLYPFQLLKEKLLQPWLNQLEDLVDERLD
AELILAWLKSELLSRVGGRYAFTGQAVAARMAVVQLSRGAATPPNSARTKSLFSLLLSLELASLRVSVIDLGEQAIGSLP
LLQGRLNVDALLLIPDPNHSGSEQTEMLTVLAQMSFPCRFVGPFAPTLISLSAFWAPSMTDLIGQIPSRSMGKVNISHKG
KGKSIGVSQSEQGNSGENNDIS
>Mature_342_residues
MKQDTQSITNDEPNDGVLLPIGEVSALTGVNAVTLRAWQRRFGLVIPARTPKGHRLYTSKNIQEIHEINAWLAKGVAISK
VKPLLMSAAKLSSEMIESQVVDLWGEQIIALNAALFDFNQHKLQQILDDAFGLYPFQLLKEKLLQPWLNQLEDLVDERLD
AELILAWLKSELLSRVGGRYAFTGQAVAARMAVVQLSRGAATPPNSARTKSLFSLLLSLELASLRVSVIDLGEQAIGSLP
LLQGRLNVDALLLIPDPNHSGSEQTEMLTVLAQMSFPCRFVGPFAPTLISLSAFWAPSMTDLIGQIPSRSMGKVNISHKG
KGKSIGVSQSEQGNSGENNDIS

Specific function: Transcriptional activator of the csg genes required for production of the curli (AgF) [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788448, Length=129, Percent_Identity=41.8604651162791, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787409, Length=70, Percent_Identity=50, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551 [H]

Pfam domain/function: PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 37299; Mature: 37299

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQDTQSITNDEPNDGVLLPIGEVSALTGVNAVTLRAWQRRFGLVIPARTPKGHRLYTSK
CCCCCCCCCCCCCCCCEEEECCCHHHHHCCHHHHHHHHHHHHCEEEECCCCCCCEEECCC
NIQEIHEINAWLAKGVAISKVKPLLMSAAKLSSEMIESQVVDLWGEQIIALNAALFDFNQ
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HKLQQILDDAFGLYPFQLLKEKLLQPWLNQLEDLVDERLDAELILAWLKSELLSRVGGRY
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
AFTGQAVAARMAVVQLSRGAATPPNSARTKSLFSLLLSLELASLRVSVIDLGEQAIGSLP
EECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCC
LLQGRLNVDALLLIPDPNHSGSEQTEMLTVLAQMSFPCRFVGPFAPTLISLSAFWAPSMT
CEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHCCCCHH
DLIGQIPSRSMGKVNISHKGKGKSIGVSQSEQGNSGENNDIS
HHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQDTQSITNDEPNDGVLLPIGEVSALTGVNAVTLRAWQRRFGLVIPARTPKGHRLYTSK
CCCCCCCCCCCCCCCCEEEECCCHHHHHCCHHHHHHHHHHHHCEEEECCCCCCCEEECCC
NIQEIHEINAWLAKGVAISKVKPLLMSAAKLSSEMIESQVVDLWGEQIIALNAALFDFNQ
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HKLQQILDDAFGLYPFQLLKEKLLQPWLNQLEDLVDERLDAELILAWLKSELLSRVGGRY
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
AFTGQAVAARMAVVQLSRGAATPPNSARTKSLFSLLLSLELASLRVSVIDLGEQAIGSLP
EECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCC
LLQGRLNVDALLLIPDPNHSGSEQTEMLTVLAQMSFPCRFVGPFAPTLISLSAFWAPSMT
CEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHCCCCHH
DLIGQIPSRSMGKVNISHKGKGKSIGVSQSEQGNSGENNDIS
HHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11489123; 9278503 [H]