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The map label for this gene is luxQ [H]

Identifier: 126174347

GI number: 126174347

Start: 2470548

End: 2472506

Strand: Direct

Name: luxQ [H]

Synonym: Sbal_2129

Alternate gene names: 126174347

Gene position: 2470548-2472506 (Clockwise)

Preceding gene: 126174346

Following gene: 126174348

Centisome position: 48.18

GC content: 43.7

Gene sequence:

>1959_bases
ATGAGCGTTAAATACAGTGCTTGCATCAATATGTTCAGTGGCTTATGGGTCACAATATTAGTGCTGTGGCTAACCTTGTC
CCACTCGCTGTATGAGTTTGACGCTATTTACGATAAAAAAGCGCAGGCGGTTTTTACTTCCTCGCGGGATATGTTCTTAC
AACATAAGATCATGTTGGATGCGCTGAAATCTTTTTTCCACGCGTCGAGTAAGGTGACGTCAGAGGAGTTTGAGATTTTT
GCCAAGGATTTACTTAAAATCAAATCTGCCGTCGCTTTTACGCTGACCCCCAGTCATGAACTGGCCTATATCTCAGATAA
AACGATGGCAACTGAGCTTCAACAGCTTGAGCTAGTCAAGGATCCTAAAGGGGAGCTTAAGGCGAGCCTTGCCAATTACA
CTTTGGCTGTGGTGGCCATTGATGAGCCAAATATGCCTTATCTCGTTTATGCCGTTTCTCATCAGCGGATACTCGCGCGA
ATCGAACAAGAGCAGGGCGATCAGCGGATACTCGCGCGAATCGAACAAGAGCAGGGCGTTTGCATTACCTATCAATTTGA
ACAGTCATTTGAGCAGTCGTTACTGCAAAACTCATCCTGTAATCTTAAGTTAGCCAGCGGCCTATTTTCATTATTTAATT
ACTCTGATAGCCAAACCTTAGCTATCCCTGAATATCAAACCCGAGTGAGTTTACAGGTACAATATCAAGTGCCGCAAAAA
GAAGTTATCGAGCTTATCGTGATCATCCTACTGATTGCAGCCCTTGGCATAGTGTTGTCCTTCCTTTTGTACTTTAAGTC
TAAAAATCAGCAGATTGTGGAGCAAATTAAGCTCGATAATCGCGCTAAACTAGCCGTACTTTCGAGCATTAATCATGAAA
TCCGCACCCCCATCAATGCCATTCTTGGCTATAGTCGCATGCTAAAAAAAGCCCTCTCACAACCACAGGAACTGGATAAA
ATCGTCGATAAAATGGCTTGGTCTGCCAACTTACTCTATTCGGTTGCCGAAAATACCTTAAATTACAGCAAGGCAGAAGC
AGGGCAGTTAAAACTGAATTTACATTCGGTGAACTTACACGAGTATGTGGGCAATATTCAGGACTATTACCGTGCGTTTA
GTGCAACCTCCGGCAAACGTTTACACATTGTAGTAAATGAGTCTTTGCCGCAGTTTATTGAACTCGATGGGACTAAGTTA
TTCCAACTCATGACCAACATTATCAATAATGCGTTCAAATACAGTACGGGTAGCGAAGTGCATTGCTATATGGATTTACA
CCTTAAAGCGAATGCTAAAGATCATCGTCCTATGCTTAGGGTGCTGATCCGCGATTTTGGCGATGGTATGTCGAAGGAGG
CGCAGCGCGCTTTAGTCGATCCCTTTATGCACGCCGCTAACTCACCTATTGCCGCGACATCGGGTATGGGACTCGGACTC
TATACGTGTAATCGATTGCTTGAGCAGATTGGCGGTCGGTTTAGGCTGCGCAGTCAAAAGGGCAAAGGCACCACAGTGTT
ACTGCATTTCCCCTGTCAGCTCAGCGCAGCGAAAGAACGATTAACACTTCAATATGATCAACAAAAAGTGCTGATCATAG
ATGACAATCTGTTTAATCTTGAAATTTGTCGCGCCATGCTGGAGCACTATCATTTTCAAACCTTCAGTACTGATAATACA
GAGCAAGCCCTGAAGATGTTGGTTAAGCATTTGCCACAGATTGTCATTGTGGATTATCGTTTACAAGAAATGAACGGTTT
ACAACTGGTAAGGCAGATGCAGCAAGTATTACAAAACTTGGTGAGTGATAGCCCTATTGAACATCACTGTCGTTTCTTTT
TGCTCTCCGCGAATGACTGCGATGATATTCCCGAGTTAGCGTCATTTCCTGAGGTGCATTTCATGCAGAAACCATTTAGT
GCCGAAGTCTTTCTCAGCAAATTAGCGGTAAAAGAGTAA

Upstream 100 bases:

>100_bases
TTGCAGCTTAAGAATACCGTGCCTATGGCTAATTCTTGCGATCAAGAACAGCTTAAGCATCAGTTAAGTGATTTACTCAA
TGCCGTAATGGATTACGTCA

Downstream 100 bases:

>100_bases
ACCATCAACATATTGAATGTTATATAGAAATATGATTTTCTGACTTCATCCAATTGGTACTGGAATACTGCAAATATCTT
TGCAGTTAATGTGTAATCTA

Product: integral membrane sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 651

Protein sequence:

>652_residues
MSVKYSACINMFSGLWVTILVLWLTLSHSLYEFDAIYDKKAQAVFTSSRDMFLQHKIMLDALKSFFHASSKVTSEEFEIF
AKDLLKIKSAVAFTLTPSHELAYISDKTMATELQQLELVKDPKGELKASLANYTLAVVAIDEPNMPYLVYAVSHQRILAR
IEQEQGDQRILARIEQEQGVCITYQFEQSFEQSLLQNSSCNLKLASGLFSLFNYSDSQTLAIPEYQTRVSLQVQYQVPQK
EVIELIVIILLIAALGIVLSFLLYFKSKNQQIVEQIKLDNRAKLAVLSSINHEIRTPINAILGYSRMLKKALSQPQELDK
IVDKMAWSANLLYSVAENTLNYSKAEAGQLKLNLHSVNLHEYVGNIQDYYRAFSATSGKRLHIVVNESLPQFIELDGTKL
FQLMTNIINNAFKYSTGSEVHCYMDLHLKANAKDHRPMLRVLIRDFGDGMSKEAQRALVDPFMHAANSPIAATSGMGLGL
YTCNRLLEQIGGRFRLRSQKGKGTTVLLHFPCQLSAAKERLTLQYDQQKVLIIDDNLFNLEICRAMLEHYHFQTFSTDNT
EQALKMLVKHLPQIVIVDYRLQEMNGLQLVRQMQQVLQNLVSDSPIEHHCRFFLLSANDCDDIPELASFPEVHFMQKPFS
AEVFLSKLAVKE

Sequences:

>Translated_652_residues
MSVKYSACINMFSGLWVTILVLWLTLSHSLYEFDAIYDKKAQAVFTSSRDMFLQHKIMLDALKSFFHASSKVTSEEFEIF
AKDLLKIKSAVAFTLTPSHELAYISDKTMATELQQLELVKDPKGELKASLANYTLAVVAIDEPNMPYLVYAVSHQRILAR
IEQEQGDQRILARIEQEQGVCITYQFEQSFEQSLLQNSSCNLKLASGLFSLFNYSDSQTLAIPEYQTRVSLQVQYQVPQK
EVIELIVIILLIAALGIVLSFLLYFKSKNQQIVEQIKLDNRAKLAVLSSINHEIRTPINAILGYSRMLKKALSQPQELDK
IVDKMAWSANLLYSVAENTLNYSKAEAGQLKLNLHSVNLHEYVGNIQDYYRAFSATSGKRLHIVVNESLPQFIELDGTKL
FQLMTNIINNAFKYSTGSEVHCYMDLHLKANAKDHRPMLRVLIRDFGDGMSKEAQRALVDPFMHAANSPIAATSGMGLGL
YTCNRLLEQIGGRFRLRSQKGKGTTVLLHFPCQLSAAKERLTLQYDQQKVLIIDDNLFNLEICRAMLEHYHFQTFSTDNT
EQALKMLVKHLPQIVIVDYRLQEMNGLQLVRQMQQVLQNLVSDSPIEHHCRFFLLSANDCDDIPELASFPEVHFMQKPFS
AEVFLSKLAVKE
>Mature_651_residues
SVKYSACINMFSGLWVTILVLWLTLSHSLYEFDAIYDKKAQAVFTSSRDMFLQHKIMLDALKSFFHASSKVTSEEFEIFA
KDLLKIKSAVAFTLTPSHELAYISDKTMATELQQLELVKDPKGELKASLANYTLAVVAIDEPNMPYLVYAVSHQRILARI
EQEQGDQRILARIEQEQGVCITYQFEQSFEQSLLQNSSCNLKLASGLFSLFNYSDSQTLAIPEYQTRVSLQVQYQVPQKE
VIELIVIILLIAALGIVLSFLLYFKSKNQQIVEQIKLDNRAKLAVLSSINHEIRTPINAILGYSRMLKKALSQPQELDKI
VDKMAWSANLLYSVAENTLNYSKAEAGQLKLNLHSVNLHEYVGNIQDYYRAFSATSGKRLHIVVNESLPQFIELDGTKLF
QLMTNIINNAFKYSTGSEVHCYMDLHLKANAKDHRPMLRVLIRDFGDGMSKEAQRALVDPFMHAANSPIAATSGMGLGLY
TCNRLLEQIGGRFRLRSQKGKGTTVLLHFPCQLSAAKERLTLQYDQQKVLIIDDNLFNLEICRAMLEHYHFQTFSTDNTE
QALKMLVKHLPQIVIVDYRLQEMNGLQLVRQMQQVLQNLVSDSPIEHHCRFFLLSANDCDDIPELASFPEVHFMQKPFSA
EVFLSKLAVKE

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=325, Percent_Identity=26.4615384615385, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI48994928, Length=368, Percent_Identity=25.2717391304348, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=28.0851063829787, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=25.6198347107438, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI87081816, Length=333, Percent_Identity=26.7267267267267, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790436, Length=287, Percent_Identity=24.0418118466899, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74209; Mature: 74078

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKYSACINMFSGLWVTILVLWLTLSHSLYEFDAIYDKKAQAVFTSSRDMFLQHKIMLD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCHHHHHHHHHHH
ALKSFFHASSKVTSEEFEIFAKDLLKIKSAVAFTLTPSHELAYISDKTMATELQQLELVK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCHHHHHHHHHHHHHC
DPKGELKASLANYTLAVVAIDEPNMPYLVYAVSHQRILARIEQEQGDQRILARIEQEQGV
CCCHHHHHHHCCEEEEEEEECCCCCCEEEEEECHHHHHHHHHHHCCHHHHHHHHHHCCCE
CITYQFEQSFEQSLLQNSSCNLKLASGLFSLFNYSDSQTLAIPEYQTRVSLQVQYQVPQK
EEEEHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCCEEECCCCCCEEEEEEEEECCHH
EVIELIVIILLIAALGIVLSFLLYFKSKNQQIVEQIKLDNRAKLAVLSSINHEIRTPINA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHCCHHHHCHHHH
ILGYSRMLKKALSQPQELDKIVDKMAWSANLLYSVAENTLNYSKAEAGQLKLNLHSVNLH
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHH
EYVGNIQDYYRAFSATSGKRLHIVVNESLPQFIELDGTKLFQLMTNIINNAFKYSTGSEV
HHHCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCEE
HCYMDLHLKANAKDHRPMLRVLIRDFGDGMSKEAQRALVDPFMHAANSPIAATSGMGLGL
EEEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCHH
YTCNRLLEQIGGRFRLRSQKGKGTTVLLHFPCQLSAAKERLTLQYDQQKVLIIDDNLFNL
HHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCHHHHHHEEEEECCCEEEEEECCCCCH
EICRAMLEHYHFQTFSTDNTEQALKMLVKHLPQIVIVDYRLQEMNGLQLVRQMQQVLQNL
HHHHHHHHHHCCEECCCCCHHHHHHHHHHHCCCEEEEEHHHHHCCHHHHHHHHHHHHHHH
VSDSPIEHHCRFFLLSANDCDDIPELASFPEVHFMQKPFSAEVFLSKLAVKE
HCCCCCCCCCEEEEEECCCCCCCHHHHCCCCHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SVKYSACINMFSGLWVTILVLWLTLSHSLYEFDAIYDKKAQAVFTSSRDMFLQHKIMLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCHHHHHHHHHHH
ALKSFFHASSKVTSEEFEIFAKDLLKIKSAVAFTLTPSHELAYISDKTMATELQQLELVK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCEEEECCHHHHHHHHHHHHHC
DPKGELKASLANYTLAVVAIDEPNMPYLVYAVSHQRILARIEQEQGDQRILARIEQEQGV
CCCHHHHHHHCCEEEEEEEECCCCCCEEEEEECHHHHHHHHHHHCCHHHHHHHHHHCCCE
CITYQFEQSFEQSLLQNSSCNLKLASGLFSLFNYSDSQTLAIPEYQTRVSLQVQYQVPQK
EEEEHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCCCEEECCCCCCEEEEEEEEECCHH
EVIELIVIILLIAALGIVLSFLLYFKSKNQQIVEQIKLDNRAKLAVLSSINHEIRTPINA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHCCHHHHCHHHH
ILGYSRMLKKALSQPQELDKIVDKMAWSANLLYSVAENTLNYSKAEAGQLKLNLHSVNLH
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHH
EYVGNIQDYYRAFSATSGKRLHIVVNESLPQFIELDGTKLFQLMTNIINNAFKYSTGSEV
HHHCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCEE
HCYMDLHLKANAKDHRPMLRVLIRDFGDGMSKEAQRALVDPFMHAANSPIAATSGMGLGL
EEEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCHH
YTCNRLLEQIGGRFRLRSQKGKGTTVLLHFPCQLSAAKERLTLQYDQQKVLIIDDNLFNL
HHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCHHHHHHEEEEECCCEEEEEECCCCCH
EICRAMLEHYHFQTFSTDNTEQALKMLVKHLPQIVIVDYRLQEMNGLQLVRQMQQVLQNL
HHHHHHHHHHCCEECCCCCHHHHHHHHHHHCCCEEEEEHHHHHCCHHHHHHHHHHHHHHH
VSDSPIEHHCRFFLLSANDCDDIPELASFPEVHFMQKPFSAEVFLSKLAVKE
HCCCCCCCCCEEEEEECCCCCCCHHHHCCCCHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA