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The map label for this gene is serC [H]

Identifier: 126174284

GI number: 126174284

Start: 2394025

End: 2395116

Strand: Direct

Name: serC [H]

Synonym: Sbal_2063

Alternate gene names: 126174284

Gene position: 2394025-2395116 (Clockwise)

Preceding gene: 126174283

Following gene: 126174285

Centisome position: 46.69

GC content: 46.61

Gene sequence:

>1092_bases
GTGAGCGCGATTTATAATTTCTGTGCTGGACCTGCAATGTTACCCGCAGCGGTAATGAAAAAAGCACAACAGGAATTACT
TGATTGGAATGGCCAAGGCGTTTCCGTGATGGAAATCAGCCACCGAAGTAAAGAGTTCATCGCGCTGACCGAGCAAGCCG
AGTCCGATTTACGTGAACTGATGCAGATCCCTGCAAATTACCATGTGCTATTTATGCACGGCGGTGGCCGCGGACAGTTC
TCTGCTGTCGTGAATAATTTTCTCGGCGAGCAGGGTAAAGCCCTGTATTTAGTCAGTGGCCAATGGTCATCTGCCGCGTT
AGCAGAAGCGCAGAAACTGGCGGGTGAAGCACAAATTGATAGTCTGAATATTGTTGAAAAACACAATGGACTCAATGCGG
TTGTCTTACCTGACTTACATAAAATCGATGCCGATTATCGCTATGTTCACTACTGTCCCAATGAGACAGTAGATGGTATC
GAAATTTTTGACGAATTAGACTCACCTTGGCCAATTGTTGCCGATTTATCATCAACAATCATGTCCCGTGAAATCGACGT
CAGCCGCTACGGCTTGATTTACGCCGGTGCGCAAAAGAACATAGGTCCATCGGGTCTGTCGATAGTGATAGTACGCGATG
ACATGTTAAAACTGCCGAGTTTACCGCAGTCGTCCATCATGGACTATCGTCTAGCCGTCGAGCATGATTCTATGTTCAAC
ACGCCACCAACCTTTGCTTGGTACCTTGCCGCTGAAGTCTTTGCTTGGCTGAAATCGACTGGCGGTATTTCGAGTATTGC
GAAAATTAATCAACAAAAAGCGCAGATGTTGTATCAATGCATTGATGGTAATGCTTTCTACCGTAATGGTGTTGTTGCAG
CGAATCGCTCACAAATGAACGTGACTTTCCAATTAGTCAACGAAGCGCTCGATAGTGAGTTCCTAAAGCAAGCCCAAATA
GCTGGACTCGTTGCCCTCAAGGGCCATCGTATCGTAGGTGGCATGCGTGCTAGCCTTTATAATGCTATGCCACTCGATGG
CATAGTTGCCTTGGTCAAGTTTATGAACGAGTTTGCGGCTAAACATAGCTAG

Upstream 100 bases:

>100_bases
CGTTTTTTTAATGGCATTGATTGTTGGTAGCATTATTCGTTTTAGAATGATTTCGTATTTATCAATACATACATCATGGT
TGGGATTAAGGAGAGTGTCA

Downstream 100 bases:

>100_bases
GCTTAGCTATCTATATAGTCACTCACTAGCTTGTTGCGCTTAGCGCCTAGGTTTTGCTGCCTGCACATAAACGTTATGCT
TATTGAATGTTTATCATCAG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSAIYNFCAGPAMLPAAVMKKAQQELLDWNGQGVSVMEISHRSKEFIALTEQAESDLRELMQIPANYHVLFMHGGGRGQF
SAVVNNFLGEQGKALYLVSGQWSSAALAEAQKLAGEAQIDSLNIVEKHNGLNAVVLPDLHKIDADYRYVHYCPNETVDGI
EIFDELDSPWPIVADLSSTIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLPQSSIMDYRLAVEHDSMFN
TPPTFAWYLAAEVFAWLKSTGGISSIAKINQQKAQMLYQCIDGNAFYRNGVVAANRSQMNVTFQLVNEALDSEFLKQAQI
AGLVALKGHRIVGGMRASLYNAMPLDGIVALVKFMNEFAAKHS

Sequences:

>Translated_363_residues
MSAIYNFCAGPAMLPAAVMKKAQQELLDWNGQGVSVMEISHRSKEFIALTEQAESDLRELMQIPANYHVLFMHGGGRGQF
SAVVNNFLGEQGKALYLVSGQWSSAALAEAQKLAGEAQIDSLNIVEKHNGLNAVVLPDLHKIDADYRYVHYCPNETVDGI
EIFDELDSPWPIVADLSSTIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLPQSSIMDYRLAVEHDSMFN
TPPTFAWYLAAEVFAWLKSTGGISSIAKINQQKAQMLYQCIDGNAFYRNGVVAANRSQMNVTFQLVNEALDSEFLKQAQI
AGLVALKGHRIVGGMRASLYNAMPLDGIVALVKFMNEFAAKHS
>Mature_362_residues
SAIYNFCAGPAMLPAAVMKKAQQELLDWNGQGVSVMEISHRSKEFIALTEQAESDLRELMQIPANYHVLFMHGGGRGQFS
AVVNNFLGEQGKALYLVSGQWSSAALAEAQKLAGEAQIDSLNIVEKHNGLNAVVLPDLHKIDADYRYVHYCPNETVDGIE
IFDELDSPWPIVADLSSTIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLPQSSIMDYRLAVEHDSMFNT
PPTFAWYLAAEVFAWLKSTGGISSIAKINQQKAQMLYQCIDGNAFYRNGVVAANRSQMNVTFQLVNEALDSEFLKQAQIA
GLVALKGHRIVGGMRASLYNAMPLDGIVALVKFMNEFAAKHS

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=369, Percent_Identity=41.1924119241192, Blast_Score=287, Evalue=9e-78,
Organism=Homo sapiens, GI10863955, Length=365, Percent_Identity=36.7123287671233, Blast_Score=239, Evalue=3e-63,
Organism=Escherichia coli, GI1787136, Length=364, Percent_Identity=56.8681318681319, Blast_Score=421, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17506897, Length=367, Percent_Identity=42.5068119891008, Blast_Score=280, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6324758, Length=389, Percent_Identity=39.8457583547558, Blast_Score=253, Evalue=4e-68,
Organism=Drosophila melanogaster, GI21356589, Length=364, Percent_Identity=43.6813186813187, Blast_Score=307, Evalue=8e-84,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39883; Mature: 39752

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIYNFCAGPAMLPAAVMKKAQQELLDWNGQGVSVMEISHRSKEFIALTEQAESDLREL
CCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHEEEHHHHHHHHHHH
MQIPANYHVLFMHGGGRGQFSAVVNNFLGEQGKALYLVSGQWSSAALAEAQKLAGEAQID
HHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCC
SLNIVEKHNGLNAVVLPDLHKIDADYRYVHYCPNETVDGIEIFDELDSPWPIVADLSSTI
CEEEEECCCCCCEEECCCHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHHH
MSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLPQSSIMDYRLAVEHDSMFN
HHHCCCHHHCEEEEECCCCCCCCCCEEEEEEECCHHCCCCCCHHHHHHEEEEEECCCCCC
TPPTFAWYLAAEVFAWLKSTGGISSIAKINQQKAQMLYQCIDGNAFYRNGVVAANRSQMN
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCC
VTFQLVNEALDSEFLKQAQIAGLVALKGHRIVGGMRASLYNAMPLDGIVALVKFMNEFAA
HHHHHHHHHHHHHHHHHHHHHHEEEECCCEEECHHHHHHHCCCCHHHHHHHHHHHHHHHH
KHS
CCC
>Mature Secondary Structure 
SAIYNFCAGPAMLPAAVMKKAQQELLDWNGQGVSVMEISHRSKEFIALTEQAESDLREL
CCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHEEEHHHHHHHHHHH
MQIPANYHVLFMHGGGRGQFSAVVNNFLGEQGKALYLVSGQWSSAALAEAQKLAGEAQID
HHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCC
SLNIVEKHNGLNAVVLPDLHKIDADYRYVHYCPNETVDGIEIFDELDSPWPIVADLSSTI
CEEEEECCCCCCEEECCCHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHHH
MSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLPQSSIMDYRLAVEHDSMFN
HHHCCCHHHCEEEEECCCCCCCCCCEEEEEEECCHHCCCCCCHHHHHHEEEEEECCCCCC
TPPTFAWYLAAEVFAWLKSTGGISSIAKINQQKAQMLYQCIDGNAFYRNGVVAANRSQMN
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCC
VTFQLVNEALDSEFLKQAQIAGLVALKGHRIVGGMRASLYNAMPLDGIVALVKFMNEFAA
HHHHHHHHHHHHHHHHHHHHHHEEEECCCEEECHHHHHHHCCCCHHHHHHHHHHHHHHHH
KHS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]