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The map label for this gene is cpxR [H]

Identifier: 126174271

GI number: 126174271

Start: 2376500

End: 2377180

Strand: Direct

Name: cpxR [H]

Synonym: Sbal_2050

Alternate gene names: 126174271

Gene position: 2376500-2377180 (Clockwise)

Preceding gene: 126174266

Following gene: 126174272

Centisome position: 46.35

GC content: 42.88

Gene sequence:

>681_bases
ATGAGTAAAATACTCTTAGTCGATGATGATCCCTTGTTTAGTGTGTGGTTGGCCGATGCCTTGGGCACACAAGGGCATCA
AGTTGCATGTGCGGAAAATGGTGTCGATGGTCTGGCATGCATTGAAAGTTTCGCTCCCGACATCATAGTGCTTGATTTAG
TCATGCCACAAATGAATGGTTTTGAGCTGTTAAAAGCGCGGGAATGCTCAACGCCGGTATTGATGATTTCTGCACGGGAT
AATGAAGACGATCGCATCACAGGTTATGAATTGGGGGCCGATGATTTTTTGAGTAAACCATTTAGCATCAAAGAGCTATT
TGTTCGCTTACGTGCTTTAGAGCGGCGTCTTTGTTCTCGTCAATCTCAATCGCCGCAAATAGCGACTGTAGCAGCGAAAG
TGATTAACTTTGATGATATGAGTCATAGGATCACCATTGGCACGCGTTATGTCGATTTGACTCAAACCGAATTTAAATTA
TTTAAATATCTGTTTGAAAGGAAAGGTCAAGTCATCACGAAACAAGAGTTGCAACGCTCAGTATTACAAAAAGATCTGGG
CCGATTTGACCGCAATCTCGATATGCACATTAGTAACACTCGCCGTAAATTAGCCAACATCAGCTTGCCGCGTAACTTAA
TCAATACAGTGCGCGGCCAAGGTTATAGTTTTATGGCTTAA

Upstream 100 bases:

>100_bases
AGTTTTCAACATCACACTTCTTAACGAATGTAATAGGTCTAGAGTCATCTCGATTCGCATGGTAATATAAATGATATAGA
TTCTCGTTTGGGTTTTAAGG

Downstream 100 bases:

>100_bases
CACCATCGTTTACTACTTTGTTAACGGCTAAGTTTGAACGGATGTTTGGCGTGAAACTTGGTCAATAAAAGGTCGACTGC
AACTGCCTTGACTGAATTTA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSKILLVDDDPLFSVWLADALGTQGHQVACAENGVDGLACIESFAPDIIVLDLVMPQMNGFELLKARECSTPVLMISARD
NEDDRITGYELGADDFLSKPFSIKELFVRLRALERRLCSRQSQSPQIATVAAKVINFDDMSHRITIGTRYVDLTQTEFKL
FKYLFERKGQVITKQELQRSVLQKDLGRFDRNLDMHISNTRRKLANISLPRNLINTVRGQGYSFMA

Sequences:

>Translated_226_residues
MSKILLVDDDPLFSVWLADALGTQGHQVACAENGVDGLACIESFAPDIIVLDLVMPQMNGFELLKARECSTPVLMISARD
NEDDRITGYELGADDFLSKPFSIKELFVRLRALERRLCSRQSQSPQIATVAAKVINFDDMSHRITIGTRYVDLTQTEFKL
FKYLFERKGQVITKQELQRSVLQKDLGRFDRNLDMHISNTRRKLANISLPRNLINTVRGQGYSFMA
>Mature_225_residues
SKILLVDDDPLFSVWLADALGTQGHQVACAENGVDGLACIESFAPDIIVLDLVMPQMNGFELLKARECSTPVLMISARDN
EDDRITGYELGADDFLSKPFSIKELFVRLRALERRLCSRQSQSPQIATVAAKVINFDDMSHRITIGTRYVDLTQTEFKLF
KYLFERKGQVITKQELQRSVLQKDLGRFDRNLDMHISNTRRKLANISLPRNLINTVRGQGYSFMA

Specific function: Member of a two-component regulatory system [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=41.304347826087, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=35.3982300884956, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=32.15859030837, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=32.4561403508772, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=31.2775330396476, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=234, Percent_Identity=35.042735042735, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=32.3404255319149, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=30.3571428571429, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=29.646017699115, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=31.4159292035398, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=31.7180616740088, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=28.3842794759825, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=27.3913043478261, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=24.3589743589744, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=33.0508474576271, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787487, Length=114, Percent_Identity=38.5964912280702, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=34.1463414634146, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI145693157, Length=103, Percent_Identity=34.9514563106796, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25633; Mature: 25502

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKILLVDDDPLFSVWLADALGTQGHQVACAENGVDGLACIESFAPDIIVLDLVMPQMNG
CCEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCCEEEEEEHHCCCCC
FELLKARECSTPVLMISARDNEDDRITGYELGADDFLSKPFSIKELFVRLRALERRLCSR
HHHHHHHCCCCCEEEEEECCCCCCCEEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHC
QSQSPQIATVAAKVINFDDMSHRITIGTRYVDLTQTEFKLFKYLFERKGQVITKQELQRS
CCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCCEECHHHHHHH
VLQKDLGRFDRNLDMHISNTRRKLANISLPRNLINTVRGQGYSFMA
HHHHHHHHHCCCCCEEEHHHHHHHHHCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SKILLVDDDPLFSVWLADALGTQGHQVACAENGVDGLACIESFAPDIIVLDLVMPQMNG
CEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCCEEEEEEHHCCCCC
FELLKARECSTPVLMISARDNEDDRITGYELGADDFLSKPFSIKELFVRLRALERRLCSR
HHHHHHHCCCCCEEEEEECCCCCCCEEEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHC
QSQSPQIATVAAKVINFDDMSHRITIGTRYVDLTQTEFKLFKYLFERKGQVITKQELQRS
CCCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCCEECHHHHHHH
VLQKDLGRFDRNLDMHISNTRRKLANISLPRNLINTVRGQGYSFMA
HHHHHHHHHCCCCCEEEHHHHHHHHHCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]