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The map label for this gene is ruvB [H]

Identifier: 126174264

GI number: 126174264

Start: 2366526

End: 2367530

Strand: Direct

Name: ruvB [H]

Synonym: Sbal_2042

Alternate gene names: 126174264

Gene position: 2366526-2367530 (Clockwise)

Preceding gene: 126174263

Following gene: 126174265

Centisome position: 46.15

GC content: 50.45

Gene sequence:

>1005_bases
ATGATTGAGGCAGACAGACTCATCCAGCCGCAGATCCAAGCTCAAGATGAATCCATCGACAGGGCGATGCGCCCTAAAAT
GCTCGATGAATACACGGGCCAAGATCACACGCGGGCTCAGCTTAAGGTGTTTATTCAAGCGGCGAAGAATCGTAACGAAG
CCTTAGACCATATGTTGATCTACGGTCCGCCAGGATTGGGTAAAACCACCTTGGCTATGATTGTGGCGAACGAGATGGGG
GTAAACATTAAATCTACCTCGGGTCCCGTGCTTGAAAAAGCCGGTGATCTCGCAGCTCTCCTGACCAATCTTGAATCCGG
TGATGTGTTATTCATCGATGAAATCCACCGATTAAGCCCTGTGGTGGAAGAGATTTTGTATCCGGCTATGGAAGATTATC
AGCTGGATATCATGATAGGTGAAGGACCTGCGGCACGTTCTATCAAGCTTGATTTACCGCCGTTCACTCTAGTGGGCGCG
ACAACACGGGCAGGGGCGTTAACCTCACCACTTCGGGCGCGTTTTGGGATCCCGCTGCGGCTTGAGTTCTATAACATCAA
AGATTTAAGCACCATAGTCACGCGTTCGGCGCAGGTTATGGAGCTGGATATTGATGCCGAAGGCGCATTTGAAATTGCGC
GCCGTTCACGCGGCACACCGCGAATAGCCAACCGATTGCTGCGCCGCGTGCGGGATTACGCGCAGGTGAAGCATGACGGC
GCAGTCACTAAGTTTGTGGCCGAACACGCTTTAGACTTGCTAGATGTGGATAGTGAAGGTTTCGATTATATGGATCGCAA
ATTGTTACTGGCTATTATCGATAAATTTATCGGTGGACCAGTAGGACTAGACAACTTAGCCGCAGCCATAGGCGAAGAAC
GTGAAACCATCGAAGATGTGTTAGAACCTTTCTTGATCCAACAAGGGTTTATCCAACGCACGCCCCGCGGCCGAATTGCA
ACCGCACGGGCATATCAGCATTTTGAGTTGATCAAACCCGAATAG

Upstream 100 bases:

>100_bases
AGGGCATGGATTCAGAGACTTTGATCAAAGCTGCCCTTAAGTCGATGCTTTGATTGAACAATGATGATTATTAAGATGAA
AGCTGCGAGAAGGAAGAACA

Downstream 100 bases:

>100_bases
CCATCTGCTTGATAATACCGATAATGAAAGGCGACCTAAGAGGTCGCCTTTTTTATGGTTAAAATATACCTTTGCGTACA
ATTTGGGTGAAGTAAAAGCG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MIEADRLIQPQIQAQDESIDRAMRPKMLDEYTGQDHTRAQLKVFIQAAKNRNEALDHMLIYGPPGLGKTTLAMIVANEMG
VNIKSTSGPVLEKAGDLAALLTNLESGDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGA
TTRAGALTSPLRARFGIPLRLEFYNIKDLSTIVTRSAQVMELDIDAEGAFEIARRSRGTPRIANRLLRRVRDYAQVKHDG
AVTKFVAEHALDLLDVDSEGFDYMDRKLLLAIIDKFIGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGRIA
TARAYQHFELIKPE

Sequences:

>Translated_334_residues
MIEADRLIQPQIQAQDESIDRAMRPKMLDEYTGQDHTRAQLKVFIQAAKNRNEALDHMLIYGPPGLGKTTLAMIVANEMG
VNIKSTSGPVLEKAGDLAALLTNLESGDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGA
TTRAGALTSPLRARFGIPLRLEFYNIKDLSTIVTRSAQVMELDIDAEGAFEIARRSRGTPRIANRLLRRVRDYAQVKHDG
AVTKFVAEHALDLLDVDSEGFDYMDRKLLLAIIDKFIGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGRIA
TARAYQHFELIKPE
>Mature_334_residues
MIEADRLIQPQIQAQDESIDRAMRPKMLDEYTGQDHTRAQLKVFIQAAKNRNEALDHMLIYGPPGLGKTTLAMIVANEMG
VNIKSTSGPVLEKAGDLAALLTNLESGDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGA
TTRAGALTSPLRARFGIPLRLEFYNIKDLSTIVTRSAQVMELDIDAEGAFEIARRSRGTPRIANRLLRRVRDYAQVKHDG
AVTKFVAEHALDLLDVDSEGFDYMDRKLLLAIIDKFIGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGRIA
TARAYQHFELIKPE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=334, Percent_Identity=74.8502994011976, Blast_Score=519, Evalue=1e-148,
Organism=Escherichia coli, GI1787119, Length=186, Percent_Identity=29.5698924731183, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37158; Mature: 37158

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEADRLIQPQIQAQDESIDRAMRPKMLDEYTGQDHTRAQLKVFIQAAKNRNEALDHMLI
CCCCCCCCCCHHHCCHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHEEEE
YGPPGLGKTTLAMIVANEMGVNIKSTSGPVLEKAGDLAALLTNLESGDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHH
VVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGALTSPLRARFGIPLR
HHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHCCCCEE
LEFYNIKDLSTIVTRSAQVMELDIDAEGAFEIARRSRGTPRIANRLLRRVRDYAQVKHDG
EEEECCHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
AVTKFVAEHALDLLDVDSEGFDYMDRKLLLAIIDKFIGGPVGLDNLAAAIGEERETIEDV
HHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHH
LEPFLIQQGFIQRTPRGRIATARAYQHFELIKPE
HHHHHHHHHHHHCCCCCCEEHHHHHHHHEECCCC
>Mature Secondary Structure
MIEADRLIQPQIQAQDESIDRAMRPKMLDEYTGQDHTRAQLKVFIQAAKNRNEALDHMLI
CCCCCCCCCCHHHCCHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHEEEE
YGPPGLGKTTLAMIVANEMGVNIKSTSGPVLEKAGDLAALLTNLESGDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHH
VVEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGALTSPLRARFGIPLR
HHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHCCCCEE
LEFYNIKDLSTIVTRSAQVMELDIDAEGAFEIARRSRGTPRIANRLLRRVRDYAQVKHDG
EEEECCHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
AVTKFVAEHALDLLDVDSEGFDYMDRKLLLAIIDKFIGGPVGLDNLAAAIGEERETIEDV
HHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHH
LEPFLIQQGFIQRTPRGRIATARAYQHFELIKPE
HHHHHHHHHHHHCCCCCCEEHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA