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The map label for this gene is insF1 [H]

Identifier: 126174229

GI number: 126174229

Start: 2326737

End: 2327546

Strand: Direct

Name: insF1 [H]

Synonym: Sbal_2006

Alternate gene names: 126174229

Gene position: 2326737-2327546 (Clockwise)

Preceding gene: 126174228

Following gene: 126174233

Centisome position: 45.38

GC content: 45.56

Gene sequence:

>810_bases
ATGAGTGTCAGTAAGTCAGGCTATTACGATTGGCATAAACGCCCTGCAAACGTGATAAGCCTTGAAACACTGAAGCTTTA
TCGCCTTGTTAGACAGCTATTTAAGCAAAGTCGAGGCAGCTTAGGAAATCGTGAAATGGTGAAGAAATTGCGCAAGGAAG
GCTACCAGGTTGGTCGCTATCTCGTTCGTAAAATTATGCACCGCCTTCGACTCAAAGCAACCCAGCGACGCGCTTACAAG
GTGACGACACAGCGAAAACACTCAGATGCAGTGGCAGATAACCTGCTAAACATGAACTTTAACCCCGTATCGGCTAATGA
GGTTTGGGCGGGTGACGTGACCTATTTAAAGACGGGTGAGGGCTGGATGTATTTAGCTGTGGTGATGGATTTATATTCAC
GCCGGATTGTGGGATGGCACATAGACAAACGCATGACCACGGATTTGATATCTAAGGCATTAATAAAAGCCTACAACCTG
CGCCAACCGGCCAGAGGGCTGGTATTTCACAGTGACCGAGGCTCGCAATATACCAGTAAGCAATTCGGTAGGCTGCTATT
GAGCTATGGTATCCGAGCCAGCATGGGTGATGTGGGAGCGTGTTGGGATAATGCCGTTGTTGAGCGATTCTTTGGCAGCT
TAAAACACGATTGGATTTTTAAAGTTAATCAACCAACAAGGGAGTTTATGAAGCAAGATGTGACTGCTTACATGAAATAT
TACAACTTGGAGCGACTTCATTCTGCTAATGGTGATCTGTCACCTGTAGAGTTTGAAAATTCTCAACTAAAAGTGTCCAG
TTTGGGTTGA

Upstream 100 bases:

>100_bases
TAAAAAAGGCAAGCGCCTTCTTTGCGAGAGAAATGAAGTAAGATTTCGTTTCATCAAACAGCAATCTAACCTGTTTCCTA
TAACACTGTTATGCCGAGTA

Downstream 100 bases:

>100_bases
CCAGTACAATACGGGGCATCCAGAATATACAATGAGTTCGGGCACGTAACAAACGCCTCAAGAGGGACTGTTAACGCGTG
GCGTTTGCAGTCTCATTGAG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSVSKSGYYDWHKRPANVISLETLKLYRLVRQLFKQSRGSLGNREMVKKLRKEGYQVGRYLVRKIMHRLRLKATQRRAYK
VTTQRKHSDAVADNLLNMNFNPVSANEVWAGDVTYLKTGEGWMYLAVVMDLYSRRIVGWHIDKRMTTDLISKALIKAYNL
RQPARGLVFHSDRGSQYTSKQFGRLLLSYGIRASMGDVGACWDNAVVERFFGSLKHDWIFKVNQPTREFMKQDVTAYMKY
YNLERLHSANGDLSPVEFENSQLKVSSLG

Sequences:

>Translated_269_residues
MSVSKSGYYDWHKRPANVISLETLKLYRLVRQLFKQSRGSLGNREMVKKLRKEGYQVGRYLVRKIMHRLRLKATQRRAYK
VTTQRKHSDAVADNLLNMNFNPVSANEVWAGDVTYLKTGEGWMYLAVVMDLYSRRIVGWHIDKRMTTDLISKALIKAYNL
RQPARGLVFHSDRGSQYTSKQFGRLLLSYGIRASMGDVGACWDNAVVERFFGSLKHDWIFKVNQPTREFMKQDVTAYMKY
YNLERLHSANGDLSPVEFENSQLKVSSLG
>Mature_268_residues
SVSKSGYYDWHKRPANVISLETLKLYRLVRQLFKQSRGSLGNREMVKKLRKEGYQVGRYLVRKIMHRLRLKATQRRAYKV
TTQRKHSDAVADNLLNMNFNPVSANEVWAGDVTYLKTGEGWMYLAVVMDLYSRRIVGWHIDKRMTTDLISKALIKAYNLR
QPARGLVFHSDRGSQYTSKQFGRLLLSYGIRASMGDVGACWDNAVVERFFGSLKHDWIFKVNQPTREFMKQDVTAYMKYY
NLERLHSANGDLSPVEFENSQLKVSSLG

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=211, Percent_Identity=36.4928909952607, Blast_Score=145, Evalue=3e-35,
Organism=Escherichia coli, GI1788405, Length=266, Percent_Identity=37.593984962406, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1787263, Length=266, Percent_Identity=37.593984962406, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1786753, Length=266, Percent_Identity=37.593984962406, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1786570, Length=266, Percent_Identity=37.593984962406, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1786490, Length=266, Percent_Identity=37.593984962406, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1789981, Length=234, Percent_Identity=32.0512820512821, Blast_Score=132, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31249; Mature: 31117

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSKSGYYDWHKRPANVISLETLKLYRLVRQLFKQSRGSLGNREMVKKLRKEGYQVGRY
CCCCCCCCCCHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LVRKIMHRLRLKATQRRAYKVTTQRKHSDAVADNLLNMNFNPVSANEVWAGDVTYLKTGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCEEEEECCC
GWMYLAVVMDLYSRRIVGWHIDKRMTTDLISKALIKAYNLRQPARGLVFHSDRGSQYTSK
CHHHHHHHHHHHHCCHHEEECCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHH
QFGRLLLSYGIRASMGDVGACWDNAVVERFFGSLKHDWIFKVNQPTREFMKQDVTAYMKY
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHH
YNLERLHSANGDLSPVEFENSQLKVSSLG
HHHHHHHCCCCCCCCEEECCCEEEEECCC
>Mature Secondary Structure 
SVSKSGYYDWHKRPANVISLETLKLYRLVRQLFKQSRGSLGNREMVKKLRKEGYQVGRY
CCCCCCCCCHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LVRKIMHRLRLKATQRRAYKVTTQRKHSDAVADNLLNMNFNPVSANEVWAGDVTYLKTGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCEEEEECCC
GWMYLAVVMDLYSRRIVGWHIDKRMTTDLISKALIKAYNLRQPARGLVFHSDRGSQYTSK
CHHHHHHHHHHHHCCHHEEECCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHH
QFGRLLLSYGIRASMGDVGACWDNAVVERFFGSLKHDWIFKVNQPTREFMKQDVTAYMKY
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHH
YNLERLHSANGDLSPVEFENSQLKVSSLG
HHHHHHHCCCCCCCCEEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]