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The map label for this gene is yscN [H]

Identifier: 126174194

GI number: 126174194

Start: 2285407

End: 2286738

Strand: Direct

Name: yscN [H]

Synonym: Sbal_1970

Alternate gene names: 126174194

Gene position: 2285407-2286738 (Clockwise)

Preceding gene: 126174193

Following gene: 126174195

Centisome position: 44.57

GC content: 50.83

Gene sequence:

>1332_bases
ATGAAATTACCCAGTAAAGAAACACTTTATGCACAACTCGAACCTCGCTTATTCGCTGCTCAGAGTCTGTTGCCTGTGCA
ATCGGTTCGCTATTTCGGCAAAGTTCAAGAGGTGGGCGCCACGCTCGTGCGTGCAACTTTGCCCGGTGCGCATCAAGGAG
AGCTTTGTCTCATTGGCAATCGCCTACGTGCCGAAGTGGTTGCGGTCAAAGGCAATGAAGCCCTGTTATCGCCCTTCGAC
GTTACGGCGGGACTATGCAGTGGGGAGTTAGTGGAAACATTAGGCCACGGGCATCAAGTCCCCTTAGGACAAGGTCTGCT
AGGTCGAGTTGTTGACGGCCTTGGTGCTCCTATGGATGGCTATGGACTTACGGCAACGGCATTAAGACCTAACCAAGGTT
CAGCCCCTAATCCATTATCACGACAACTGATTGATACTGTCATGCCCATGGGGATCCGCGCTATTGACAGCGCTCTAGCC
TGTGGCGTCGGCCAAAGGATTGGTATTTTTGCTGCAGCAGGAGGGGGGAAAAGTACCTTGCTTGGCATGATCGCTGCGCA
CTGCCAAGCAGATGTGATCGTACTGGCCTTAGTCGGCGAGCGTGGCCGTGAAGTCCGTGAGTTTATTGAATATAACCTCA
CTCCAGAGGCAAGAGCGCGCACTGTGATGGTAGTTGCCACATCGGATCGTCCTCCGCTTGAGCGAATGAAAGCCACACTA
ACAGCAACGACGATTGCCGAGTACTTTCGTGATCAAGGTAAGAATGTGCTGTTGATGGTGGATTCGCTAACCAGATTTGC
TCGCAGTGCCAGAGAAATTGCGTTGGCGGCTGGCGAGAGCCCAGTGTCGAGCGGTTATCCACCAAGTGTCTTTGTCAATT
TATCGGCCCTAGTCGAGCGAGCAGGCCCTGCAGCCCAAGGCAGTATCACTGGCATTTATACCGTACTGGTTGAAGGGGAT
GATATGAATGAACCTATCGCCGATGAAGTTCGTTCCTTACTCGATGGCCACATAGTGCTATCACGTCGACTCGCGGGAGC
GGGGCATTACCCTGCAATTGATATCAATGCCAGTGTCAGCAGGGTAATGGATCAGATTGTTAGCCCTGAACAGCGTTGTC
ATGCCGCCAAGATGCGCCAGTTACTGGCATTGTATCAAGAGGTTCAATTACTGATCCGAGTGGGTGAATACGTTAAAGGT
GCAGATAAAGAGACCGATGAAGCCGTCGCTCGCCATCAGGATATTCAGCAGTTTTTATGTCAATCAGTCAATGAATTCAG
TCCCTATGAAGAGACACTACAAAAATTACAGTTATTGCTTTCAAGCCATTAA

Upstream 100 bases:

>100_bases
TCAGGAATTAGGCGACGATGCAGAAATAAAAGTCATAGGCCAAGTGGACTTAGTGGGTGACATGCTCGATGCCGCACTGG
CGAGCTAATGGAGGCGATAG

Downstream 100 bases:

>100_bases
TGGGAGCGACTCAAAAATGAACCCATCCCAACTTACAATAAAAGACAGACAATTATTACAGCGGTTACTCGTAATTCGTA
GCGACAAAGAAGCTAAATTA

Product: type III secretion system ATPase

Products: NA

Alternate protein names: Yop proteins secretion ATPase [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MKLPSKETLYAQLEPRLFAAQSLLPVQSVRYFGKVQEVGATLVRATLPGAHQGELCLIGNRLRAEVVAVKGNEALLSPFD
VTAGLCSGELVETLGHGHQVPLGQGLLGRVVDGLGAPMDGYGLTATALRPNQGSAPNPLSRQLIDTVMPMGIRAIDSALA
CGVGQRIGIFAAAGGGKSTLLGMIAAHCQADVIVLALVGERGREVREFIEYNLTPEARARTVMVVATSDRPPLERMKATL
TATTIAEYFRDQGKNVLLMVDSLTRFARSAREIALAAGESPVSSGYPPSVFVNLSALVERAGPAAQGSITGIYTVLVEGD
DMNEPIADEVRSLLDGHIVLSRRLAGAGHYPAIDINASVSRVMDQIVSPEQRCHAAKMRQLLALYQEVQLLIRVGEYVKG
ADKETDEAVARHQDIQQFLCQSVNEFSPYEETLQKLQLLLSSH

Sequences:

>Translated_443_residues
MKLPSKETLYAQLEPRLFAAQSLLPVQSVRYFGKVQEVGATLVRATLPGAHQGELCLIGNRLRAEVVAVKGNEALLSPFD
VTAGLCSGELVETLGHGHQVPLGQGLLGRVVDGLGAPMDGYGLTATALRPNQGSAPNPLSRQLIDTVMPMGIRAIDSALA
CGVGQRIGIFAAAGGGKSTLLGMIAAHCQADVIVLALVGERGREVREFIEYNLTPEARARTVMVVATSDRPPLERMKATL
TATTIAEYFRDQGKNVLLMVDSLTRFARSAREIALAAGESPVSSGYPPSVFVNLSALVERAGPAAQGSITGIYTVLVEGD
DMNEPIADEVRSLLDGHIVLSRRLAGAGHYPAIDINASVSRVMDQIVSPEQRCHAAKMRQLLALYQEVQLLIRVGEYVKG
ADKETDEAVARHQDIQQFLCQSVNEFSPYEETLQKLQLLLSSH
>Mature_443_residues
MKLPSKETLYAQLEPRLFAAQSLLPVQSVRYFGKVQEVGATLVRATLPGAHQGELCLIGNRLRAEVVAVKGNEALLSPFD
VTAGLCSGELVETLGHGHQVPLGQGLLGRVVDGLGAPMDGYGLTATALRPNQGSAPNPLSRQLIDTVMPMGIRAIDSALA
CGVGQRIGIFAAAGGGKSTLLGMIAAHCQADVIVLALVGERGREVREFIEYNLTPEARARTVMVVATSDRPPLERMKATL
TATTIAEYFRDQGKNVLLMVDSLTRFARSAREIALAAGESPVSSGYPPSVFVNLSALVERAGPAAQGSITGIYTVLVEGD
DMNEPIADEVRSLLDGHIVLSRRLAGAGHYPAIDINASVSRVMDQIVSPEQRCHAAKMRQLLALYQEVQLLIRVGEYVKG
ADKETDEAVARHQDIQQFLCQSVNEFSPYEETLQKLQLLLSSH

Specific function: Is a component of the Yop secretion machinery using ATP, and it is either the energizer of this machinery, or part of it [H]

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm. Note=But connected to the inner membrane possibly through LcrD (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=388, Percent_Identity=31.4432989690722, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI50345984, Length=378, Percent_Identity=30.1587301587302, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI4757810, Length=378, Percent_Identity=30.1587301587302, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI19913426, Length=419, Percent_Identity=27.6849642004773, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI19913428, Length=416, Percent_Identity=27.4038461538462, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI19913424, Length=229, Percent_Identity=31.0043668122271, Blast_Score=115, Evalue=9e-26,
Organism=Escherichia coli, GI1788251, Length=432, Percent_Identity=45.8333333333333, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1790170, Length=353, Percent_Identity=33.1444759206799, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1790172, Length=420, Percent_Identity=29.2857142857143, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790217, Length=240, Percent_Identity=27.9166666666667, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25144756, Length=387, Percent_Identity=29.9741602067183, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71988063, Length=350, Percent_Identity=31.1428571428571, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71988080, Length=426, Percent_Identity=28.169014084507, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17565854, Length=336, Percent_Identity=28.5714285714286, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17570191, Length=368, Percent_Identity=27.7173913043478, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17510931, Length=364, Percent_Identity=27.7472527472527, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71988074, Length=324, Percent_Identity=29.320987654321, Blast_Score=103, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322581, Length=357, Percent_Identity=32.2128851540616, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6319370, Length=357, Percent_Identity=32.4929971988796, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319603, Length=351, Percent_Identity=29.3447293447293, Blast_Score=136, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6320016, Length=280, Percent_Identity=30, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24638766, Length=388, Percent_Identity=30.4123711340206, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI28574560, Length=360, Percent_Identity=32.2222222222222, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24658560, Length=354, Percent_Identity=31.0734463276836, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281361666, Length=346, Percent_Identity=28.9017341040462, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24646341, Length=346, Percent_Identity=28.9017341040462, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI17136796, Length=346, Percent_Identity=28.9017341040462, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24583988, Length=373, Percent_Identity=29.2225201072386, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24583986, Length=373, Percent_Identity=29.2225201072386, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24583984, Length=373, Percent_Identity=29.2225201072386, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24583992, Length=356, Percent_Identity=30.0561797752809, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI20129479, Length=319, Percent_Identity=28.5266457680251, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR004100
- InterPro:   IPR005714
- InterPro:   IPR013380 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 47495; Mature: 47495

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPSKETLYAQLEPRLFAAQSLLPVQSVRYFGKVQEVGATLVRATLPGAHQGELCLIGN
CCCCCCCCCCEECCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
RLRAEVVAVKGNEALLSPFDVTAGLCSGELVETLGHGHQVPLGQGLLGRVVDGLGAPMDG
CCEEEEEEEECCCCCCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCC
YGLTATALRPNQGSAPNPLSRQLIDTVMPMGIRAIDSALACGVGQRIGIFAAAGGGKSTL
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHH
LGMIAAHCQADVIVLALVGERGREVREFIEYNLTPEARARTVMVVATSDRPPLERMKATL
HHHHHHHHHHCEEEEEEECCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHH
TATTIAEYFRDQGKNVLLMVDSLTRFARSAREIALAAGESPVSSGYPPSVFVNLSALVER
HHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEHHHHHHH
AGPAAQGSITGIYTVLVEGDDMNEPIADEVRSLLDGHIVLSRRLAGAGHYPAIDINASVS
CCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCEEECCCHHH
RVMDQIVSPEQRCHAAKMRQLLALYQEVQLLIRVGEYVKGADKETDEAVARHQDIQQFLC
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
QSVNEFSPYEETLQKLQLLLSSH
HHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLPSKETLYAQLEPRLFAAQSLLPVQSVRYFGKVQEVGATLVRATLPGAHQGELCLIGN
CCCCCCCCCCEECCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
RLRAEVVAVKGNEALLSPFDVTAGLCSGELVETLGHGHQVPLGQGLLGRVVDGLGAPMDG
CCEEEEEEEECCCCCCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCC
YGLTATALRPNQGSAPNPLSRQLIDTVMPMGIRAIDSALACGVGQRIGIFAAAGGGKSTL
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHH
LGMIAAHCQADVIVLALVGERGREVREFIEYNLTPEARARTVMVVATSDRPPLERMKATL
HHHHHHHHHHCEEEEEEECCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHH
TATTIAEYFRDQGKNVLLMVDSLTRFARSAREIALAAGESPVSSGYPPSVFVNLSALVER
HHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEHHHHHHH
AGPAAQGSITGIYTVLVEGDDMNEPIADEVRSLLDGHIVLSRRLAGAGHYPAIDINASVS
CCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCEEECCCHHH
RVMDQIVSPEQRCHAAKMRQLLALYQEVQLLIRVGEYVKGADKETDEAVARHQDIQQFLC
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
QSVNEFSPYEETLQKLQLLLSSH
HHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8132449; 2160939 [H]