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The map label for this gene is hlyB [H]

Identifier: 126173732

GI number: 126173732

Start: 1735820

End: 1737466

Strand: Reverse

Name: hlyB [H]

Synonym: Sbal_1494

Alternate gene names: 126173732

Gene position: 1737466-1735820 (Counterclockwise)

Preceding gene: 126173742

Following gene: 126173729

Centisome position: 33.89

GC content: 45.78

Gene sequence:

>1647_bases
ATGCTAAATCAGATGACGCTTAAGACCCAGTTTATCGGGGTCATCGCTATTCCCTGTATTGCTCTTATCTTAATCAGCTT
AACAGCCATTCAAGGCTTATCTGGTATGCAAGATCAAACTAAAACACTCGCCGAAAATACCAGCGCGCCATTAAGGTCGA
TGGCGGAAGTTGCGTCCCGTATTCCTCGGATGCGAGTGGGCATTGATATTATTATCTTGCAAGAAATACCGACGATGAAG
GATCAAAAAGGCGTATTAACCCGTGTAACAGAAACCCGTGCGGAGGACATTCCAGAAATGGATGCGGCATTAAAAGCTGC
CCGTGACGCTCAGGTAAACCCCATTACCCGTGTCGAAGTACAAAAGTTGATCGACCTCTTTGATAAAGTCAAAAGTGACG
AACTTGCGCCTATGCTTACAGCGATGGAAAAGGGAGAAGTGGCAAAATCGCAAGAAATCTATCGTAACCAGTTCGCAGCT
AGCTACAACATAATGAGAAAGAGTACCGATGCCATTCTTGACTCATTGCTACAACAAGGCAACACCAGCTTCGTTGACAG
TCAAAAAAACTACCAAGAAACACGCATGGAAATGTTTGTTGTTTTAACCATCGCTTTGATTATTTCAATATTTCTAGGTT
TTATTATGCTGCGTCGTCTACGACTTCGCGTGGCATCGTTACAACAGCATATTTCTTCTGCCAGTGACAAACTTGATTTG
CATAATATGATCGAGTTAAAAGGCCAAGACGAACTCAGTGATATTGCCCTGCACTTTAATCAGTTTGTGCTGAAGATACG
TAATGCGATTGAAGCCGTAGCTGACAACTCACGCCAACTCGCCCATACGGCAAACGATGTCGCCAGCAAAGCCCAAGCAA
CCCATAGAAATTGTATTAACGAGCGCGATCGCACCACGCAAATCGCAACGGCAATCCATGAGATGGGCACCACAGTGGAC
AATATTGCTGGCAACGCAACCCAAGCGGCTAATGCAGCCAAAGAAGCAGATAATCAAGCGCATAATGGCGCGAGTGTGGT
CGCCAAAGCTCGCCAGGGTGTCAGCTCATTATCCATTGAAATTCAACACATCAGCACTGACATTACTTCGCTCGCGACGC
AAACCAATTCTATCGGCAGTATTTTGGATACCATACGCAGCATTTCAGAACAAACTAACTTGCTAGCACTCAACGCAGCC
ATTGAAGCCGCACGCGCTGGCGAGACAGGTCGAGGTTTTGCCGTTGTCGCCGACGAAGTCCGAAACCTTGCCAGTCGTTC
AGCGTCATCGACAGATGAAATTCAAACAATGATTAACAAGCTGCAGGAGCAATCGTCCAAAACAGTGACTGCCATCAAGC
GGGGCCACGAACAAAGCGGTATGGTCGTCAAGCAGGCAGATGATGCCAATGACTCCTTAACCCTGATTACTTCGCATATT
AGCCAAATCAGCGACATGAACATTCAAGTCGCCACCGCGACAGAAGAGCAGTCTATGGTTGTAGCAGAGATAAGCCGCAA
TGTTGAAGAAATTAATCAGTTAACGACTGAAACATCGGAGATTGCCGACGAGTTAACGGCATCCAGCGCAAACTTACAAA
AACTATCGGTTCACTTAGATAAATTAGTGACCCAATTTAAGTTATAA

Upstream 100 bases:

>100_bases
GAATAAAAATTCAAGCTATTGTTCCTATTTAATAATGCCAAATTATCTAACCATAAACATCCCAACCAGATAACCCTAAA
TAAAAGTAGGAAGGAAAGAC

Downstream 100 bases:

>100_bases
GCGGTAAAAGTTATCATATACCGCAGGACGCTTAGTGCATTCAATCAACGTAATGCTTCAAAAACATAGTGACTTTAAAA
AAAAAAACAGTGACTTAAAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MLNQMTLKTQFIGVIAIPCIALILISLTAIQGLSGMQDQTKTLAENTSAPLRSMAEVASRIPRMRVGIDIIILQEIPTMK
DQKGVLTRVTETRAEDIPEMDAALKAARDAQVNPITRVEVQKLIDLFDKVKSDELAPMLTAMEKGEVAKSQEIYRNQFAA
SYNIMRKSTDAILDSLLQQGNTSFVDSQKNYQETRMEMFVVLTIALIISIFLGFIMLRRLRLRVASLQQHISSASDKLDL
HNMIELKGQDELSDIALHFNQFVLKIRNAIEAVADNSRQLAHTANDVASKAQATHRNCINERDRTTQIATAIHEMGTTVD
NIAGNATQAANAAKEADNQAHNGASVVAKARQGVSSLSIEIQHISTDITSLATQTNSIGSILDTIRSISEQTNLLALNAA
IEAARAGETGRGFAVVADEVRNLASRSASSTDEIQTMINKLQEQSSKTVTAIKRGHEQSGMVVKQADDANDSLTLITSHI
SQISDMNIQVATATEEQSMVVAEISRNVEEINQLTTETSEIADELTASSANLQKLSVHLDKLVTQFKL

Sequences:

>Translated_548_residues
MLNQMTLKTQFIGVIAIPCIALILISLTAIQGLSGMQDQTKTLAENTSAPLRSMAEVASRIPRMRVGIDIIILQEIPTMK
DQKGVLTRVTETRAEDIPEMDAALKAARDAQVNPITRVEVQKLIDLFDKVKSDELAPMLTAMEKGEVAKSQEIYRNQFAA
SYNIMRKSTDAILDSLLQQGNTSFVDSQKNYQETRMEMFVVLTIALIISIFLGFIMLRRLRLRVASLQQHISSASDKLDL
HNMIELKGQDELSDIALHFNQFVLKIRNAIEAVADNSRQLAHTANDVASKAQATHRNCINERDRTTQIATAIHEMGTTVD
NIAGNATQAANAAKEADNQAHNGASVVAKARQGVSSLSIEIQHISTDITSLATQTNSIGSILDTIRSISEQTNLLALNAA
IEAARAGETGRGFAVVADEVRNLASRSASSTDEIQTMINKLQEQSSKTVTAIKRGHEQSGMVVKQADDANDSLTLITSHI
SQISDMNIQVATATEEQSMVVAEISRNVEEINQLTTETSEIADELTASSANLQKLSVHLDKLVTQFKL
>Mature_548_residues
MLNQMTLKTQFIGVIAIPCIALILISLTAIQGLSGMQDQTKTLAENTSAPLRSMAEVASRIPRMRVGIDIIILQEIPTMK
DQKGVLTRVTETRAEDIPEMDAALKAARDAQVNPITRVEVQKLIDLFDKVKSDELAPMLTAMEKGEVAKSQEIYRNQFAA
SYNIMRKSTDAILDSLLQQGNTSFVDSQKNYQETRMEMFVVLTIALIISIFLGFIMLRRLRLRVASLQQHISSASDKLDL
HNMIELKGQDELSDIALHFNQFVLKIRNAIEAVADNSRQLAHTANDVASKAQATHRNCINERDRTTQIATAIHEMGTTVD
NIAGNATQAANAAKEADNQAHNGASVVAKARQGVSSLSIEIQHISTDITSLATQTNSIGSILDTIRSISEQTNLLALNAA
IEAARAGETGRGFAVVADEVRNLASRSASSTDEIQTMINKLQEQSSKTVTAIKRGHEQSGMVVKQADDANDSLTLITSHI
SQISDMNIQVATATEEQSMVVAEISRNVEEINQLTTETSEIADELTASSANLQKLSVHLDKLVTQFKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=430, Percent_Identity=26.7441860465116, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787690, Length=371, Percent_Identity=29.1105121293801, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788195, Length=343, Percent_Identity=29.7376093294461, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI2367378, Length=418, Percent_Identity=27.7511961722488, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789453, Length=174, Percent_Identity=37.9310344827586, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59860; Mature: 59860

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS50885 HAMP ; PS00059 ADH_ZINC ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNQMTLKTQFIGVIAIPCIALILISLTAIQGLSGMQDQTKTLAENTSAPLRSMAEVASR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
IPRMRVGIDIIILQEIPTMKDQKGVLTRVTETRAEDIPEMDAALKAARDAQVNPITRVEV
CCCHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHH
QKLIDLFDKVKSDELAPMLTAMEKGEVAKSQEIYRNQFAASYNIMRKSTDAILDSLLQQG
HHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NTSFVDSQKNYQETRMEMFVVLTIALIISIFLGFIMLRRLRLRVASLQQHISSASDKLDL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
HNMIELKGQDELSDIALHFNQFVLKIRNAIEAVADNSRQLAHTANDVASKAQATHRNCIN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
ERDRTTQIATAIHEMGTTVDNIAGNATQAANAAKEADNQAHNGASVVAKARQGVSSLSIE
HHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHEEE
IQHISTDITSLATQTNSIGSILDTIRSISEQTNLLALNAAIEAARAGETGRGFAVVADEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHH
RNLASRSASSTDEIQTMINKLQEQSSKTVTAIKRGHEQSGMVVKQADDANDSLTLITSHI
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHH
SQISDMNIQVATATEEQSMVVAEISRNVEEINQLTTETSEIADELTASSANLQKLSVHLD
HHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KLVTQFKL
HHHHHHCC
>Mature Secondary Structure
MLNQMTLKTQFIGVIAIPCIALILISLTAIQGLSGMQDQTKTLAENTSAPLRSMAEVASR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
IPRMRVGIDIIILQEIPTMKDQKGVLTRVTETRAEDIPEMDAALKAARDAQVNPITRVEV
CCCHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHH
QKLIDLFDKVKSDELAPMLTAMEKGEVAKSQEIYRNQFAASYNIMRKSTDAILDSLLQQG
HHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NTSFVDSQKNYQETRMEMFVVLTIALIISIFLGFIMLRRLRLRVASLQQHISSASDKLDL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
HNMIELKGQDELSDIALHFNQFVLKIRNAIEAVADNSRQLAHTANDVASKAQATHRNCIN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
ERDRTTQIATAIHEMGTTVDNIAGNATQAANAAKEADNQAHNGASVVAKARQGVSSLSIE
HHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHEEE
IQHISTDITSLATQTNSIGSILDTIRSISEQTNLLALNAAIEAARAGETGRGFAVVADEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHH
RNLASRSASSTDEIQTMINKLQEQSSKTVTAIKRGHEQSGMVVKQADDANDSLTLITSHI
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHH
SQISDMNIQVATATEEQSMVVAEISRNVEEINQLTTETSEIADELTASSANLQKLSVHLD
HHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KLVTQFKL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]