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The map label for this gene is rodA [H]

Identifier: 125624442

GI number: 125624442

Start: 1621500

End: 1622744

Strand: Reverse

Name: rodA [H]

Synonym: llmg_1643

Alternate gene names: 125624442

Gene position: 1622744-1621500 (Counterclockwise)

Preceding gene: 125624443

Following gene: 125624441

Centisome position: 64.15

GC content: 37.75

Gene sequence:

>1245_bases
TTGAACAAAAAGAAAGTAAATAGATTTACATTTGATTCAAGAATTGATTATGGGCTGATATTACCAGCCTTTATGTTAAT
TTTAATTGGTCTTTACGCACTTTATGTGGCAGTAAGTCACGATCATCCGGCACAAGCCACAACTCTGGTAGTTCAACAAG
GAACCTGGGTAATCGTTGGGCTCTTCGTTGCCTTAATAGTCATGCACATGGATTCAAGATTTTTATGGAATTTAACCCCA
TTTTTCTATCTTTTAGGTCTGATTTTGATGATTTTGCCGATATTCTTCTATGATAGAGCGACTTATGCCTCAACAGGTGC
AAAAAACTGGCTTGCTTTTGGTGGACGGAATTTATTTCAGCCCTCAGAGTTTATGAAGCTTTCCTACATTCTATTTTCAG
CCCGAATTGTAGTAACTTTCCAAAATAATTTGAAAAAGAGAGTCCTCAAAGACGATTTTCGCTTAATTGGACTTTTGATT
CTTGAAACAATTCCTGTCGCAATCTTGTCAGTATTTCAAAAGGACTTTGGGACTTTCTTGGTATTTGCGGCAATCTTTGC
TGGGATTGTCTTAGTATCTGGAGTTTCTTGGAAAATACTGGCGCCAGCTTTTCTTTTTGTAGCAGCAGTCGCAGGTGGGA
TTGTGGCTTTAGTTGCTTCTCCAGAAGGACAGAAGTTTCTTGAAAGTACAAGTTTTGCAAAATATCAAGTCAATCGTTTT
ATTGCTTGGTTACATCCCTTTGAGTATTCGCAAACCTTCAGTCTTCAACAAGCACGTTCTTTGATTTCTGTCGGAGTGGG
AGGACTTTGGGGTAAAGGAATTGGCGTTGCCAATGTTAATGTTCCTGTCCGTGAATCAGATATGATTTTTACAGTTATTG
CTGAGGATTTCGGATTTGTTGGTTCAGCATTCTTGATTTTCCTTTACTTCATGTTGATTTATCGAATGATTCGAGTGACT
TTTAACTCAAATAATCAGTTCTATACTTATATTTCAACCGGTATTATCATGATGATTCTTTTCCACGTCTTTGAAAATAT
TGGAGCTGCTATTGGGGTTGTTCCATTAACGGGTATCCCTCTACCATTTATTTCCCAAGGGGGTTCGGCTTTGATGTCCA
ATATCATTGGATTAGGACTTGTTCTATCGATGAAATATAATCAACTCCCAGAATTCGTCAGAGAACAAAGACAGATTCCA
GTCAAGGGAGATAGTCGTAAAAATCGTCGTAGAAATAGAACTTAA

Upstream 100 bases:

>100_bases
CCTCAATAATAAAGTTGTTTTAGCAGATTAAAAGGGATTTGTGATTTTTTGAAATAAATTTTTTAAGGCTAAAACAATAT
TAAACTGACTGGAGCTAGTT

Downstream 100 bases:

>100_bases
AAAATTCTTAGCTTTTTATAAAAAATGAAGATTGCTAGCAGAAATGTTAGTAGTTTTTTTATTACCTTAAATATGTCTAT
AAGTCATATATAGCAAGGTG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MNKKKVNRFTFDSRIDYGLILPAFMLILIGLYALYVAVSHDHPAQATTLVVQQGTWVIVGLFVALIVMHMDSRFLWNLTP
FFYLLGLILMILPIFFYDRATYASTGAKNWLAFGGRNLFQPSEFMKLSYILFSARIVVTFQNNLKKRVLKDDFRLIGLLI
LETIPVAILSVFQKDFGTFLVFAAIFAGIVLVSGVSWKILAPAFLFVAAVAGGIVALVASPEGQKFLESTSFAKYQVNRF
IAWLHPFEYSQTFSLQQARSLISVGVGGLWGKGIGVANVNVPVRESDMIFTVIAEDFGFVGSAFLIFLYFMLIYRMIRVT
FNSNNQFYTYISTGIIMMILFHVFENIGAAIGVVPLTGIPLPFISQGGSALMSNIIGLGLVLSMKYNQLPEFVREQRQIP
VKGDSRKNRRRNRT

Sequences:

>Translated_414_residues
MNKKKVNRFTFDSRIDYGLILPAFMLILIGLYALYVAVSHDHPAQATTLVVQQGTWVIVGLFVALIVMHMDSRFLWNLTP
FFYLLGLILMILPIFFYDRATYASTGAKNWLAFGGRNLFQPSEFMKLSYILFSARIVVTFQNNLKKRVLKDDFRLIGLLI
LETIPVAILSVFQKDFGTFLVFAAIFAGIVLVSGVSWKILAPAFLFVAAVAGGIVALVASPEGQKFLESTSFAKYQVNRF
IAWLHPFEYSQTFSLQQARSLISVGVGGLWGKGIGVANVNVPVRESDMIFTVIAEDFGFVGSAFLIFLYFMLIYRMIRVT
FNSNNQFYTYISTGIIMMILFHVFENIGAAIGVVPLTGIPLPFISQGGSALMSNIIGLGLVLSMKYNQLPEFVREQRQIP
VKGDSRKNRRRNRT
>Mature_414_residues
MNKKKVNRFTFDSRIDYGLILPAFMLILIGLYALYVAVSHDHPAQATTLVVQQGTWVIVGLFVALIVMHMDSRFLWNLTP
FFYLLGLILMILPIFFYDRATYASTGAKNWLAFGGRNLFQPSEFMKLSYILFSARIVVTFQNNLKKRVLKDDFRLIGLLI
LETIPVAILSVFQKDFGTFLVFAAIFAGIVLVSGVSWKILAPAFLFVAAVAGGIVALVASPEGQKFLESTSFAKYQVNRF
IAWLHPFEYSQTFSLQQARSLISVGVGGLWGKGIGVANVNVPVRESDMIFTVIAEDFGFVGSAFLIFLYFMLIYRMIRVT
FNSNNQFYTYISTGIIMMILFHVFENIGAAIGVVPLTGIPLPFISQGGSALMSNIIGLGLVLSMKYNQLPEFVREQRQIP
VKGDSRKNRRRNRT

Specific function: This Is One Of The Proteins Responsible For The Rod Shape Of E. coli. Is Required For The Expression Of The Enzymatic Activity Of Pbp2, Which Is Thought To Synthesize Peptidoglycan In The Step Of Initiation Of Cell Elongation. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=336, Percent_Identity=29.4642857142857, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786277, Length=357, Percent_Identity=26.0504201680672, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46456; Mature: 46456

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKKVNRFTFDSRIDYGLILPAFMLILIGLYALYVAVSHDHPAQATTLVVQQGTWVIVG
CCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHH
LFVALIVMHMDSRFLWNLTPFFYLLGLILMILPIFFYDRATYASTGAKNWLAFGGRNLFQ
HHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHCCCCCCC
PSEFMKLSYILFSARIVVTFQNNLKKRVLKDDFRLIGLLILETIPVAILSVFQKDFGTFL
CHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFAAIFAGIVLVSGVSWKILAPAFLFVAAVAGGIVALVASPEGQKFLESTSFAKYQVNRF
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCHHHHHHHHH
IAWLHPFEYSQTFSLQQARSLISVGVGGLWGKGIGVANVNVPVRESDMIFTVIAEDFGFV
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHCHH
GSAFLIFLYFMLIYRMIRVTFNSNNQFYTYISTGIIMMILFHVFENIGAAIGVVPLTGIP
HHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEHCCCCCC
LPFISQGGSALMSNIIGLGLVLSMKYNQLPEFVREQRQIPVKGDSRKNRRRNRT
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCC
>Mature Secondary Structure
MNKKKVNRFTFDSRIDYGLILPAFMLILIGLYALYVAVSHDHPAQATTLVVQQGTWVIVG
CCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHH
LFVALIVMHMDSRFLWNLTPFFYLLGLILMILPIFFYDRATYASTGAKNWLAFGGRNLFQ
HHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHCCCCCCC
PSEFMKLSYILFSARIVVTFQNNLKKRVLKDDFRLIGLLILETIPVAILSVFQKDFGTFL
CHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFAAIFAGIVLVSGVSWKILAPAFLFVAAVAGGIVALVASPEGQKFLESTSFAKYQVNRF
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCHHHHHHHHH
IAWLHPFEYSQTFSLQQARSLISVGVGGLWGKGIGVANVNVPVRESDMIFTVIAEDFGFV
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEHHHHCHH
GSAFLIFLYFMLIYRMIRVTFNSNNQFYTYISTGIIMMILFHVFENIGAAIGVVPLTGIP
HHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEHCCCCCC
LPFISQGGSALMSNIIGLGLVLSMKYNQLPEFVREQRQIPVKGDSRKNRRRNRT
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]