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The map label for this gene is fdhC [H]

Identifier: 125624354

GI number: 125624354

Start: 1522750

End: 1523553

Strand: Reverse

Name: fdhC [H]

Synonym: llmg_1551

Alternate gene names: 125624354

Gene position: 1523553-1522750 (Counterclockwise)

Preceding gene: 125624355

Following gene: 125624350

Centisome position: 60.23

GC content: 38.18

Gene sequence:

>804_bases
ATGATGAATCCGGCAGAAATTTTAACTGCGACCATTCACCACGGTCAGGAAAAAATAAAACGTCCTTTTTTAGAAAAAGC
CGTTCTTGGTTTTATTGGTGGGGCAATGATTTCTTTTGGCTACTTGCTTTATATTCGGGCGATAGCTTCGGTAGCTGACG
AACTAGGAAGTCTTGCAAGTTTGATTGGAGCGAGTGTCTTTCCAATTGGGCTAATCGTTATCTTGTTGGGTGGTGGCGAG
CTGATTACTTCAAACATGACCGCTGTTTCTACTTCATTTTTTGCTAAAAAAGTGACTTTGAGTGAATTACTAAAAAATTG
GTTAATCATTACTGTATTTAATGTCCTTGGTGCTATTTTTGTCGCTTTTGTTTTTGGACATCTTGTCGGATTGACAGGTA
TTGGAGCTTACAAAACGGAGCTTCTTAGTTTAGCACAATCGAAAATAAATGCTAGTTGGTCCCAAGAATTTCTCTCAGGA
ATCGGATGTAATTGGTTTGTTGGTCTGGCAATGTGGATGTGTTATGGCGCTAAAGATGCTGCTGGAAAAGTATTAGCAGT
TTGGTTTCCGGTTATGGCTTTCGTTGCGATTGGTTTTCAGCATAGTATAGCTAATGCCTTTGTCATTCCAGCGGCAATTT
TTGAAAATGGAGCAAGCTGGCTCGATTTTGCTCATAATTTTCTATTTGTTTATCTTGGTAATCTCTTTGGAGGGTCAATA
TTTGTTGCTGGATTTTATAGTTTAGGCTATCGAAGACAAGCAAGAGAACAAGAAGAACTAAAAAATAAAGAAAAAAGTTA
CTGA

Upstream 100 bases:

>100_bases
TTGTCTAAACCCATAAATACAGTATTTTTTAGCATTCTAATATAATTTATGATAGAATGAATGAGTTATTTTATAAATAC
GCTTTCAGGAGAAAAATTAC

Downstream 100 bases:

>100_bases
CAAAAAGTCAGTAACTATTTTTTTAACTGATGATAACGATTGTACCAAATTTCAACGTATTCTTTAGAAAAAGGCCCTTT
TTCATTGTTAATCCAGTCAA

Product: putative formate dehydrogenase

Products: formate [Periplasm]; formate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MMNPAEILTATIHHGQEKIKRPFLEKAVLGFIGGAMISFGYLLYIRAIASVADELGSLASLIGASVFPIGLIVILLGGGE
LITSNMTAVSTSFFAKKVTLSELLKNWLIITVFNVLGAIFVAFVFGHLVGLTGIGAYKTELLSLAQSKINASWSQEFLSG
IGCNWFVGLAMWMCYGAKDAAGKVLAVWFPVMAFVAIGFQHSIANAFVIPAAIFENGASWLDFAHNFLFVYLGNLFGGSI
FVAGFYSLGYRRQAREQEELKNKEKSY

Sequences:

>Translated_267_residues
MMNPAEILTATIHHGQEKIKRPFLEKAVLGFIGGAMISFGYLLYIRAIASVADELGSLASLIGASVFPIGLIVILLGGGE
LITSNMTAVSTSFFAKKVTLSELLKNWLIITVFNVLGAIFVAFVFGHLVGLTGIGAYKTELLSLAQSKINASWSQEFLSG
IGCNWFVGLAMWMCYGAKDAAGKVLAVWFPVMAFVAIGFQHSIANAFVIPAAIFENGASWLDFAHNFLFVYLGNLFGGSI
FVAGFYSLGYRRQAREQEELKNKEKSY
>Mature_267_residues
MMNPAEILTATIHHGQEKIKRPFLEKAVLGFIGGAMISFGYLLYIRAIASVADELGSLASLIGASVFPIGLIVILLGGGE
LITSNMTAVSTSFFAKKVTLSELLKNWLIITVFNVLGAIFVAFVFGHLVGLTGIGAYKTELLSLAQSKINASWSQEFLSG
IGCNWFVGLAMWMCYGAKDAAGKVLAVWFPVMAFVAIGFQHSIANAFVIPAAIFENGASWLDFAHNFLFVYLGNLFGGSI
FVAGFYSLGYRRQAREQEELKNKEKSY

Specific function: Involved In The Bidirectional Transport Of Formate. [C]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI1787132, Length=275, Percent_Identity=29.0909090909091, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788837, Length=262, Percent_Identity=29.3893129770992, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI87082249, Length=243, Percent_Identity=28.3950617283951, Blast_Score=79, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321779, Length=207, Percent_Identity=27.536231884058, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 28976; Mature: 28976

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS01005 FORMATE_NITRITE_TP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate [Cytoplasm]; formate [Periplasm] [C]

Specific reaction: formate [Cytoplasm] = formate [Periplasm] formate [Periplasm] = formate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]