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The map label for this gene is ribH

Identifier: 125624333

GI number: 125624333

Start: 1501033

End: 1501497

Strand: Reverse

Name: ribH

Synonym: llmg_1529

Alternate gene names: 125624333

Gene position: 1501497-1501033 (Counterclockwise)

Preceding gene: 125624334

Following gene: 125624330

Centisome position: 59.36

GC content: 38.49

Gene sequence:

>465_bases
ATGACAGTATTTGAGGGAAATTTAACAACAGGAAATGCCAAATATGGAATTGTAGTTGCACGTTTTAACGAATTCATCAA
CGCAAAACTCTTAGCAGGGGCCTTAGATGCTCTCAAAAGACATGGTGTTCAAGAAGAACAAATTGATATTGCTTGGGTGC
CAGGAGCATTTGAAATTCCGCTTATTGCGCAAAAAATGGCGAGTTCAGATAAATATGATGCCATTATCTGCTTAGGTACG
GTGATTCGAGGTTCTACTTCACATTATGATTTTGTTTGTAGCGAGGTTTCTAAAGGGATTGCCCATGTTTCACTGAATTC
AAATATCCCTGTTATGTTTGGAGTACTGACGACAGAGAATATTGAACAAGCGATTGAACGTTCAGGAACAAAAGCAGGAA
ATAAAGGATTTGAGGTAGCAGTTGGTGCGATTGAGATGGTTGATTTGATGGCTAAAATGTCTTAA

Upstream 100 bases:

>100_bases
AAATTAAAGAAAATGAATTTGATCAGGATTATTTAAAAGTAAAGCAAACTAAAATGGGACATTTGTTCGATTAAAATAAA
AAGAAAGCATGGATAGAAAA

Downstream 100 bases:

>100_bases
GTTGTTTAAAATTTGAAATCAGACAAAATTCAAGAGTTCTGCAAAGAAAATCAATTAATAAAAAATAAAAGGAAAGCTCC
ATATTGGCTCTCCTTTTATT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MTVFEGNLTTGNAKYGIVVARFNEFINAKLLAGALDALKRHGVQEEQIDIAWVPGAFEIPLIAQKMASSDKYDAIICLGT
VIRGSTSHYDFVCSEVSKGIAHVSLNSNIPVMFGVLTTENIEQAIERSGTKAGNKGFEVAVGAIEMVDLMAKMS

Sequences:

>Translated_154_residues
MTVFEGNLTTGNAKYGIVVARFNEFINAKLLAGALDALKRHGVQEEQIDIAWVPGAFEIPLIAQKMASSDKYDAIICLGT
VIRGSTSHYDFVCSEVSKGIAHVSLNSNIPVMFGVLTTENIEQAIERSGTKAGNKGFEVAVGAIEMVDLMAKMS
>Mature_153_residues
TVFEGNLTTGNAKYGIVVARFNEFINAKLLAGALDALKRHGVQEEQIDIAWVPGAFEIPLIAQKMASSDKYDAIICLGTV
IRGSTSHYDFVCSEVSKGIAHVSLNSNIPVMFGVLTTENIEQAIERSGTKAGNKGFEVAVGAIEMVDLMAKMS

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=151, Percent_Identity=57.6158940397351, Blast_Score=186, Evalue=8e-49,
Organism=Saccharomyces cerevisiae, GI6324429, Length=142, Percent_Identity=30.2816901408451, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_LACLM (A2RLD8)

Other databases:

- EMBL:   AM406671
- RefSeq:   YP_001032816.1
- ProteinModelPortal:   A2RLD8
- SMR:   A2RLD8
- STRING:   A2RLD8
- GeneID:   4797745
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_1529
- eggNOG:   COG0054
- HOGENOM:   HBG311126
- OMA:   KAGNKGW
- ProtClustDB:   PRK00061
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16525; Mature: 16394

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVFEGNLTTGNAKYGIVVARFNEFINAKLLAGALDALKRHGVQEEQIDIAWVPGAFEIP
CEEECCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCH
LIAQKMASSDKYDAIICLGTVIRGSTSHYDFVCSEVSKGIAHVSLNSNIPVMFGVLTTEN
HHHHHHCCCCCCCEEEEEEHHHCCCCCCHHHHHHHHHCCEEEEEECCCCCEEEEEECHHH
IEQAIERSGTKAGNKGFEVAVGAIEMVDLMAKMS
HHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVFEGNLTTGNAKYGIVVARFNEFINAKLLAGALDALKRHGVQEEQIDIAWVPGAFEIP
EEECCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCH
LIAQKMASSDKYDAIICLGTVIRGSTSHYDFVCSEVSKGIAHVSLNSNIPVMFGVLTTEN
HHHHHHCCCCCCCEEEEEEHHHCCCCCCHHHHHHHHHCCEEEEEECCCCCEEEEEECHHH
IEQAIERSGTKAGNKGFEVAVGAIEMVDLMAKMS
HHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA