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The map label for this gene is 124485594

Identifier: 124485594

GI number: 124485594

Start: 754055

End: 754651

Strand: Reverse

Name: 124485594

Synonym: Mlab_0772

Alternate gene names: NA

Gene position: 754651-754055 (Counterclockwise)

Preceding gene: 124485596

Following gene: 124485593

Centisome position: 41.81

GC content: 50.42

Gene sequence:

>597_bases
ATGTCTTCCTTAGAAGAGCTCATGGCAAAAGCAAAAGACCTTCATGCTGAAGGCCACTCATCCGGTCAGATCGCTGATGA
ACTCAGCCTCTCGGTCGATACGGTCACCTGGCTTCTGACGCAGGGAAAGGCCGGGATCGCGGCACCGAAAGATGTACATA
TCGACTGGACGAACGTCAGTTCGAACACCACACTCCTTGGTGGAATCTCATCCATGATGCTGGCCCATTTTGAGGCAGCA
AACGAAGAGGAGGAGGGAGTCGACGCCGTTATCGGAATATCCGTATCGGGTGTACCTCTCGCAACGATGATCGCCGCAGA
AGACGGACTCAATCTCGCCATATACCATCCTTCAAAACACAATCCGGAAGGAAAAATCGGATCGATATCCGGAAACTTCA
GCAAAGTCTCCCAAAAACGCTGTTTAATTGTGGACGACTGCATCACAACCGGCAACACTCTTACAGAGATCGTAAATTAT
CTGCGCCGCCACAAAGCCACCCCGGTTGGCATCTGTGTAATCTTTGATAAGCGCGGTGTCAAGGAAATAGAGGGCGTTCC
GGTCTACTCGCTGTTTACAATTAAACGTATCGACTGA

Upstream 100 bases:

>100_bases
TTCACTTTTAGTAGGTTTCCCATCTTTTCTGCCGGAAGAACCTGCTTTTCAGCAGAAGTTTCACAAAAGCATATATGCGG
AAAAAGCGATTACTTCTCAT

Downstream 100 bases:

>100_bases
AGAGTCAATAACCAATACAACATATTTATATAGAAGTCCAATCCACTTTTTTAACATATTAGTACAGGAGAATAACGATT
ATGGCAAACAACTCAGGTCA

Product: orotate phosphoribosyltransferase-like protein

Products: orotate; 5-phospho-alpha-D-ribose 1-diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSSLEELMAKAKDLHAEGHSSGQIADELSLSVDTVTWLLTQGKAGIAAPKDVHIDWTNVSSNTTLLGGISSMMLAHFEAA
NEEEEGVDAVIGISVSGVPLATMIAAEDGLNLAIYHPSKHNPEGKIGSISGNFSKVSQKRCLIVDDCITTGNTLTEIVNY
LRRHKATPVGICVIFDKRGVKEIEGVPVYSLFTIKRID

Sequences:

>Translated_198_residues
MSSLEELMAKAKDLHAEGHSSGQIADELSLSVDTVTWLLTQGKAGIAAPKDVHIDWTNVSSNTTLLGGISSMMLAHFEAA
NEEEEGVDAVIGISVSGVPLATMIAAEDGLNLAIYHPSKHNPEGKIGSISGNFSKVSQKRCLIVDDCITTGNTLTEIVNY
LRRHKATPVGICVIFDKRGVKEIEGVPVYSLFTIKRID
>Mature_197_residues
SSLEELMAKAKDLHAEGHSSGQIADELSLSVDTVTWLLTQGKAGIAAPKDVHIDWTNVSSNTTLLGGISSMMLAHFEAAN
EEEEGVDAVIGISVSGVPLATMIAAEDGLNLAIYHPSKHNPEGKIGSISGNFSKVSQKRCLIVDDCITTGNTLTEIVNYL
RRHKATPVGICVIFDKRGVKEIEGVPVYSLFTIKRID

Specific function: Unknown

COG id: COG0856

COG function: function code F; Orotate phosphoribosyltransferase homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYREL_METLZ (A2SRI7)

Other databases:

- EMBL:   CP000559
- RefSeq:   YP_001030210.1
- ProteinModelPortal:   A2SRI7
- SMR:   A2SRI7
- STRING:   A2SRI7
- GeneID:   4794844
- GenomeReviews:   CP000559_GR
- KEGG:   mla:Mlab_0772
- eggNOG:   arNOG07847
- HOGENOM:   HBG497993
- OMA:   KDVHIDW
- ProtClustDB:   PRK02277
- BioCyc:   MLAB410358:MLAB_0772-MONOMER
- HAMAP:   MF_01214
- InterPro:   IPR022854
- InterPro:   IPR000836

Pfam domain/function: PF00156 Pribosyltran

EC number: 2.4.2.10

Molecular weight: Translated: 21202; Mature: 21071

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLEELMAKAKDLHAEGHSSGQIADELSLSVDTVTWLLTQGKAGIAAPKDVHIDWTNVS
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHEEEEEECCCCCCCCCCEEEEEEECCC
SNTTLLGGISSMMLAHFEAANEEEEGVDAVIGISVSGVPLATMIAAEDGLNLAIYHPSKH
CCCEEEHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEECCCCC
NPEGKIGSISGNFSKVSQKRCLIVDDCITTGNTLTEIVNYLRRHKATPVGICVIFDKRGV
CCCCCEEECCCCHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCC
KEIEGVPVYSLFTIKRID
HHHCCCCEEEEEEEEECC
>Mature Secondary Structure 
SSLEELMAKAKDLHAEGHSSGQIADELSLSVDTVTWLLTQGKAGIAAPKDVHIDWTNVS
CHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHEEEEEECCCCCCCCCCEEEEEEECCC
SNTTLLGGISSMMLAHFEAANEEEEGVDAVIGISVSGVPLATMIAAEDGLNLAIYHPSKH
CCCEEEHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEECCCCC
NPEGKIGSISGNFSKVSQKRCLIVDDCITTGNTLTEIVNYLRRHKATPVGICVIFDKRGV
CCCCCEEECCCCHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCC
KEIEGVPVYSLFTIKRID
HHHCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: orotidine 5'-phosphate; diphosphate

Specific reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA