Click here to switch to the map view.

The map label for this gene is ftsZ [H]

Identifier: 124485565

GI number: 124485565

Start: 727160

End: 728317

Strand: Reverse

Name: ftsZ [H]

Synonym: Mlab_0743

Alternate gene names: 124485565

Gene position: 728317-727160 (Counterclockwise)

Preceding gene: 124485566

Following gene: 124485564

Centisome position: 40.35

GC content: 55.87

Gene sequence:

>1158_bases
ATGCAGAGTATTATCAATGAGGCACTGAAGAACTCGGAGCTCGAAAAAGGAATGCAGACGACATCGATCGTCGATGACGA
CGACATGCTCGGACAGCCGAGAATCGTCATTGTCGGATGCGGAGGCGCAGGAAACAACACGATCAACAGACTTCACAACA
TGAAGGTCGCAGGATCCGAAACCATCGCAATCAACACCGATAAGCAGCACTTGGACATGATCCAGGCAGACAAGCGCGTT
TTGATCGGCAAATCCCTGACCCGCGGACTTGGTGCAGGAGGATTCCCCGATGTTGGCCGCCGTGCCGCCGAGATGGCACG
CCCGACCCTTGAAGAGATCTTGAAAGATGCCGACCTCGTTTTCGTCACCGCAGGCATGGGCGGAGGAACCGGAACCGGAT
CGGCACCAGTAGTCGCACAGATCGCCAAAGAGCACGGAGCCATCGTCATTGCAATGGTAAGCTATCCATTCCAGGTAGAA
CGGGCGAGAATGCTGAAAGCGGAAGACGGTCTCGAGGCAATGCGCCAGGCAGCAGACTCCGTAATCGTTCTCGACAACAA
CAGACTCAAAAACTTCGTACCGAACCTGCCGCTCGGCCAGGCATTTTCCGTCATGGATCAGCTCATCGCCGAGACTGTTA
AAGGCATCTCCGAGACGATCACCGAGCCGTCCTTAATCAACATCGACTACGCAGACGTTCGCGCCATCATGAGCAAAGGC
GGCCTTGCAGTCATGCTTGTCGGAGAGTCAAAACAGCAGAACAAGGCCGAGTCCGTTATCCGCGACTGTCTTGCCCACCC
GCTTCTCGACATCGACTTCCGCGGAGCAACCGGCAGCCTGATCCACATCACCGGCGGAAACGATCTCACGCTCCACGACG
CAGAAGAGATCGCACAGCAGCTCACCTATGAACTCGACCCGCACGCAGATGTCATCTGGGGAGCAAGAGTCCGCAAAGAT
TTCGAAGGAAAAGTTTCCGTCATGGCAATCATGACCGGCATCCAGTGTCCCCAGGTCCTCGGCGGCCACTCGGTCAGCAC
GTTCCAGGTCGGCAACACCAGCTCAAACAAATCCTCACAGAGCCCCTCGGCATCTTCCACCCATCAGCAAAATACCGCGA
CTGCACGCAGCGGTTCCTCGTTTGACTGGATCATGTAA

Upstream 100 bases:

>100_bases
TTCCTCTCCCAGAGAGGAGATAGGATTATGCGTGACAGTGATCAGATCTCCACGTTTGACGCACGATTATAAGAGTAAAA
TTATTGGGGTGTTTACAAAA

Downstream 100 bases:

>100_bases
ACCAACTCAACCAAACATCAGTTTCACACACCACTCATACATACACAAGGGGGAAATCGGACGCCAAAAGATATACCGTC
ACCATACCCCCACAGGACAT

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MQSIINEALKNSELEKGMQTTSIVDDDDMLGQPRIVIVGCGGAGNNTINRLHNMKVAGSETIAINTDKQHLDMIQADKRV
LIGKSLTRGLGAGGFPDVGRRAAEMARPTLEEILKDADLVFVTAGMGGGTGTGSAPVVAQIAKEHGAIVIAMVSYPFQVE
RARMLKAEDGLEAMRQAADSVIVLDNNRLKNFVPNLPLGQAFSVMDQLIAETVKGISETITEPSLINIDYADVRAIMSKG
GLAVMLVGESKQQNKAESVIRDCLAHPLLDIDFRGATGSLIHITGGNDLTLHDAEEIAQQLTYELDPHADVIWGARVRKD
FEGKVSVMAIMTGIQCPQVLGGHSVSTFQVGNTSSNKSSQSPSASSTHQQNTATARSGSSFDWIM

Sequences:

>Translated_385_residues
MQSIINEALKNSELEKGMQTTSIVDDDDMLGQPRIVIVGCGGAGNNTINRLHNMKVAGSETIAINTDKQHLDMIQADKRV
LIGKSLTRGLGAGGFPDVGRRAAEMARPTLEEILKDADLVFVTAGMGGGTGTGSAPVVAQIAKEHGAIVIAMVSYPFQVE
RARMLKAEDGLEAMRQAADSVIVLDNNRLKNFVPNLPLGQAFSVMDQLIAETVKGISETITEPSLINIDYADVRAIMSKG
GLAVMLVGESKQQNKAESVIRDCLAHPLLDIDFRGATGSLIHITGGNDLTLHDAEEIAQQLTYELDPHADVIWGARVRKD
FEGKVSVMAIMTGIQCPQVLGGHSVSTFQVGNTSSNKSSQSPSASSTHQQNTATARSGSSFDWIM
>Mature_385_residues
MQSIINEALKNSELEKGMQTTSIVDDDDMLGQPRIVIVGCGGAGNNTINRLHNMKVAGSETIAINTDKQHLDMIQADKRV
LIGKSLTRGLGAGGFPDVGRRAAEMARPTLEEILKDADLVFVTAGMGGGTGTGSAPVVAQIAKEHGAIVIAMVSYPFQVE
RARMLKAEDGLEAMRQAADSVIVLDNNRLKNFVPNLPLGQAFSVMDQLIAETVKGISETITEPSLINIDYADVRAIMSKG
GLAVMLVGESKQQNKAESVIRDCLAHPLLDIDFRGATGSLIHITGGNDLTLHDAEEIAQQLTYELDPHADVIWGARVRKD
FEGKVSVMAIMTGIQCPQVLGGHSVSTFQVGNTSSNKSSQSPSASSTHQQNTATARSGSSFDWIM

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Assemble at the Inner Surface of the Cytoplasmic Membrane. [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=328, Percent_Identity=36.890243902439, Blast_Score=173, Evalue=2e-44,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 41065; Mature: 41065

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSIINEALKNSELEKGMQTTSIVDDDDMLGQPRIVIVGCGGAGNNTINRLHNMKVAGSE
CHHHHHHHHHHHHHHCCCHHHEECCCHHHCCCCEEEEEECCCCCCHHHHHHHCEEECCCC
TIAINTDKQHLDMIQADKRVLIGKSLTRGLGAGGFPDVGRRAAEMARPTLEEILKDADLV
EEEEECCHHHHHHHHHCCCEEECHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
FVTAGMGGGTGTGSAPVVAQIAKEHGAIVIAMVSYPFQVERARMLKAEDGLEAMRQAADS
EEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
VIVLDNNRLKNFVPNLPLGQAFSVMDQLIAETVKGISETITEPSLINIDYADVRAIMSKG
EEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHCC
GLAVMLVGESKQQNKAESVIRDCLAHPLLDIDFRGATGSLIHITGGNDLTLHDAEEIAQQ
CEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCEEEECCHHHHHHH
LTYELDPHADVIWGARVRKDFEGKVSVMAIMTGIQCPQVLGGHSVSTFQVGNTSSNKSSQ
HCCCCCCCCCEEECHHHHCCCCCCEEEEEHHHCCCCCHHHCCCCEEEEEECCCCCCCCCC
SPSASSTHQQNTATARSGSSFDWIM
CCCCCCCCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MQSIINEALKNSELEKGMQTTSIVDDDDMLGQPRIVIVGCGGAGNNTINRLHNMKVAGSE
CHHHHHHHHHHHHHHCCCHHHEECCCHHHCCCCEEEEEECCCCCCHHHHHHHCEEECCCC
TIAINTDKQHLDMIQADKRVLIGKSLTRGLGAGGFPDVGRRAAEMARPTLEEILKDADLV
EEEEECCHHHHHHHHHCCCEEECHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
FVTAGMGGGTGTGSAPVVAQIAKEHGAIVIAMVSYPFQVERARMLKAEDGLEAMRQAADS
EEEECCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
VIVLDNNRLKNFVPNLPLGQAFSVMDQLIAETVKGISETITEPSLINIDYADVRAIMSKG
EEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHCC
GLAVMLVGESKQQNKAESVIRDCLAHPLLDIDFRGATGSLIHITGGNDLTLHDAEEIAQQ
CEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCEEEECCHHHHHHH
LTYELDPHADVIWGARVRKDFEGKVSVMAIMTGIQCPQVLGGHSVSTFQVGNTSSNKSSQ
HCCCCCCCCCEEECHHHHCCCCCCEEEEEHHHCCCCCHHHCCCCEEEEEECCCCCCCCCC
SPSASSTHQQNTATARSGSSFDWIM
CCCCCCCCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8631708; 11016950 [H]