Click here to switch to the map view.

The map label for this gene is pepQ [H]

Identifier: 124485437

GI number: 124485437

Start: 585230

End: 586423

Strand: Reverse

Name: pepQ [H]

Synonym: Mlab_0612

Alternate gene names: 124485437

Gene position: 586423-585230 (Counterclockwise)

Preceding gene: 124485438

Following gene: 124485436

Centisome position: 32.49

GC content: 47.99

Gene sequence:

>1194_bases
ATGCAAAATAATGTCCCTCTCGCTGAACTTGAAAACCGGATGGCCCGTTTTCATGCTCAGATGGATAATAAATACCCGGA
CTGGGAATATGCAGCGGTTTTTGGCAAGGTCAATCTCTATTACTTCACCGGCACGATGCAGGACGGCGTTCTTCTGATAC
CAAAACGTGATGATGCAGTTTTCTGGGTAAGAAACAGTTATTCGCGCGCGCTCGACGAATCAACATTCAACGATATTCGG
CCAATGGACAGTTTCCGCGATGCTGCAAAACAAACGGCCATTACCGGCGATACGGTGTATACGGAAACGGAAGTAATCTC
GTATGCCCACCTGCAGAGATTTTTGAAGTATTTCCCGTTCAAGCATATCGCTTCAGCTGATCGAATAATTGCAGATGTCA
GATCGGTGAAGAGTGAATATGAACTGACGCTGATGAGAAAATCCGGGGATATCCACCGCCATGTGAAAGAAGAACTGGTG
CCCAATATTCTTCGGGAAGGGATGAGCGAAGCAGAACTTGGAACCGAGCTCTATCAGATCATGATTCGTGAAGGACATCA
GGGAATCGTACGATTCGGGATGTTCGACACGGAAGTCAGGATGGGACATATCGGGTTCGGCGAGAGTTCCCTTTATCCGT
CCTATTTTAACGGAGCAAGCGGAAACCGTGGTATAGGGCCGTATGCTCCGGTCCTTGGCAGTCCCGACAGGAAACTGAAA
TACGGCGATCTCGTGTATCTGGATGTAGGATGCGGGTATCACGGATATCAGACCGATAAAACGATGACCTATATGTTTGG
CAAATCTCTGCCGGATGAGGTTATCGAGATGCACTACAAATGCGTCGATATCCAGAATGCCGTTGCCTCGATGCTGAAAC
CAGGCATGGCTCCGTCGGTGATCTATCAGACGATAATGGATGATCTCGATGAGGATTTCAAACAGAATTTCATGGGCTAC
AAAGAACGGGTGGTCAAATTCCTCGGTCACGGGATCGGCCTTCAGATCGACGAAATGCCGGTTATTGCAAAAGGATTCGA
TGAACCGCTTGCTGAAAATATGACTCTCGCTATTGAGCCGAAGAAGGGGATACAAGATATCGGGATTGTTGGGATAGAAA
ATACCTTTGTCGTCACACCTCAAGGCGGAGCGTGCCTCACAGGGAATAATCCCGGCATGATCTTGGTTGATTGA

Upstream 100 bases:

>100_bases
GCGTGTGCATCTTCGCTTCAAGGAACCGAAGCCATATTTTTGCCGTCTGAATGCATTGCCGGATGCCAAGTATTATCCCT
TTCTTCTCGATAAACTGGTT

Downstream 100 bases:

>100_bases
AGGCCTGAGGCCCATCACCATTTATCATCGCGTATTTTTTCGCATCGATAGAGTCAATTTGTCTGAAGTTGTTCTCTTCA
AAGACTCTGTTTCAAAATGA

Product: hypothetical protein

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MQNNVPLAELENRMARFHAQMDNKYPDWEYAAVFGKVNLYYFTGTMQDGVLLIPKRDDAVFWVRNSYSRALDESTFNDIR
PMDSFRDAAKQTAITGDTVYTETEVISYAHLQRFLKYFPFKHIASADRIIADVRSVKSEYELTLMRKSGDIHRHVKEELV
PNILREGMSEAELGTELYQIMIREGHQGIVRFGMFDTEVRMGHIGFGESSLYPSYFNGASGNRGIGPYAPVLGSPDRKLK
YGDLVYLDVGCGYHGYQTDKTMTYMFGKSLPDEVIEMHYKCVDIQNAVASMLKPGMAPSVIYQTIMDDLDEDFKQNFMGY
KERVVKFLGHGIGLQIDEMPVIAKGFDEPLAENMTLAIEPKKGIQDIGIVGIENTFVVTPQGGACLTGNNPGMILVD

Sequences:

>Translated_397_residues
MQNNVPLAELENRMARFHAQMDNKYPDWEYAAVFGKVNLYYFTGTMQDGVLLIPKRDDAVFWVRNSYSRALDESTFNDIR
PMDSFRDAAKQTAITGDTVYTETEVISYAHLQRFLKYFPFKHIASADRIIADVRSVKSEYELTLMRKSGDIHRHVKEELV
PNILREGMSEAELGTELYQIMIREGHQGIVRFGMFDTEVRMGHIGFGESSLYPSYFNGASGNRGIGPYAPVLGSPDRKLK
YGDLVYLDVGCGYHGYQTDKTMTYMFGKSLPDEVIEMHYKCVDIQNAVASMLKPGMAPSVIYQTIMDDLDEDFKQNFMGY
KERVVKFLGHGIGLQIDEMPVIAKGFDEPLAENMTLAIEPKKGIQDIGIVGIENTFVVTPQGGACLTGNNPGMILVD
>Mature_397_residues
MQNNVPLAELENRMARFHAQMDNKYPDWEYAAVFGKVNLYYFTGTMQDGVLLIPKRDDAVFWVRNSYSRALDESTFNDIR
PMDSFRDAAKQTAITGDTVYTETEVISYAHLQRFLKYFPFKHIASADRIIADVRSVKSEYELTLMRKSGDIHRHVKEELV
PNILREGMSEAELGTELYQIMIREGHQGIVRFGMFDTEVRMGHIGFGESSLYPSYFNGASGNRGIGPYAPVLGSPDRKLK
YGDLVYLDVGCGYHGYQTDKTMTYMFGKSLPDEVIEMHYKCVDIQNAVASMLKPGMAPSVIYQTIMDDLDEDFKQNFMGY
KERVVKFLGHGIGLQIDEMPVIAKGFDEPLAENMTLAIEPKKGIQDIGIVGIENTFVVTPQGGACLTGNNPGMILVD

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=289, Percent_Identity=25.2595155709343, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 44773; Mature: 44773

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNNVPLAELENRMARFHAQMDNKYPDWEYAAVFGKVNLYYFTGTMQDGVLLIPKRDDAV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEEEECCCCEEEEECCCCEE
FWVRNSYSRALDESTFNDIRPMDSFRDAAKQTAITGDTVYTETEVISYAHLQRFLKYFPF
EEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCH
KHIASADRIIADVRSVKSEYELTLMRKSGDIHRHVKEELVPNILREGMSEAELGTELYQI
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
MIREGHQGIVRFGMFDTEVRMGHIGFGESSLYPSYFNGASGNRGIGPYAPVLGSPDRKLK
HHHCCCCCEEEECEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
YGDLVYLDVGCGYHGYQTDKTMTYMFGKSLPDEVIEMHYKCVDIQNAVASMLKPGMAPSV
ECCEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IYQTIMDDLDEDFKQNFMGYKERVVKFLGHGIGLQIDEMPVIAKGFDEPLAENMTLAIEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHCCCCCHHHCCCEEEECC
KKGIQDIGIVGIENTFVVTPQGGACLTGNNPGMILVD
CCCCCCCCEEEECCEEEECCCCCEEEECCCCCEEEEC
>Mature Secondary Structure
MQNNVPLAELENRMARFHAQMDNKYPDWEYAAVFGKVNLYYFTGTMQDGVLLIPKRDDAV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEEEECCCCEEEEECCCCEE
FWVRNSYSRALDESTFNDIRPMDSFRDAAKQTAITGDTVYTETEVISYAHLQRFLKYFPF
EEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCCH
KHIASADRIIADVRSVKSEYELTLMRKSGDIHRHVKEELVPNILREGMSEAELGTELYQI
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
MIREGHQGIVRFGMFDTEVRMGHIGFGESSLYPSYFNGASGNRGIGPYAPVLGSPDRKLK
HHHCCCCCEEEECEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
YGDLVYLDVGCGYHGYQTDKTMTYMFGKSLPDEVIEMHYKCVDIQNAVASMLKPGMAPSV
ECCEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IYQTIMDDLDEDFKQNFMGYKERVVKFLGHGIGLQIDEMPVIAKGFDEPLAENMTLAIEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHCCCCCHHHCCCEEEECC
KKGIQDIGIVGIENTFVVTPQGGACLTGNNPGMILVD
CCCCCCCCEEEECCEEEECCCCCEEEECCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]