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The map label for this gene is exaA [H]

Identifier: 124265666

GI number: 124265666

Start: 512867

End: 514609

Strand: Direct

Name: exaA [H]

Synonym: Mpe_A0473

Alternate gene names: 124265666

Gene position: 512867-514609 (Clockwise)

Preceding gene: 124265665

Following gene: 124265670

Centisome position: 12.68

GC content: 65.63

Gene sequence:

>1743_bases
ATGCGTCTGCACCTGCTTTCTTTGTTGGTGGCTGCCGCCTGCGCCAGTGTTGGCGCCCAGGCCGCCGGCGTCACCGACGC
GATGATCGACAACGATGCCAAGACCCCGAACGACGTTCTGAGCTGGGGCATCGGCTCGCAGGGGCAGCGCTATTCCCCGC
TCAAGCAGGTCAACACCTCGACCGTGCAGAAGCTGGTGCCGGCCTGGGCCTTCTCGTTCGGCGGCGAAAAGCAGCGCGGG
CAGCAATCGCAGCCGCTGATCCATGACGGCAAGATGTTCGTCACGGCGTCTTACTCGCGGATCTACGCGCTGGACGTCAA
GACCGGCACCAAGCTCTGGAAGTATGAGCACCGCCTGCCCGAAGGCATCATGCCCTGCTGCGATGTGATCAACCGCGGTG
CCGCGCTGTACGACAACCTGGTCATCTTCGGCACGCTCGACGCCCAGCTCGTCGCGCTCGACCAGAAGACCGGCGACGTG
GTCTGGAAGGAGAAGATCGACGACTACGCGGCCGGCTACAGCTACACCGCCGCCCCGCTGATCGCCGGTGGCCTGCTGCT
GACCGGTGTGTCCGGCGGCGAATTCGGCATCGTCGGACGCGTCGAGGCGCGCGATCCCAAGACCGGCAAGATGGTCTGGA
TCCGCCCGACCGTCGAAGGTCACATGGGCTACAAGTTCGACAAGGACGGCAACAAGACCGAAATCGGCATCTCGGGCACG
ACGGGCAAGACCTGGCCGGGCGACATGTGGAAGTCGGGCGGCGCGGCCACCTGGCTGGGCGGCACCTACGACGCCAAGAC
CGGCCTGGCCTACTTCGGCACCGGCAACCCCGGCCCGTGGAACAGCCACCTGCGTCCCGGCGACAACCTGTTCTCGTGCG
CGACGGTCGCGATCGACGTCAAGACCGGCCAGATCAAGTGGCACTATCAGACCACACCGCACGACGGCTGGGACTTCGAC
GGCGTGAACGAGTTCGTCACCTTCGACATGGACGGCAAGCGCGTCGGCGGCAAGGCCGACCGCAACGGCTTCTTCTACGT
GATCGACGCCGCCAACGGCAAGCTCGAGAACGCTTTCCCCTTCGTCAAGAAGATCACCTGGGCCACCGGCATCGATCTGA
AGACCGGCCGTCCCAACTACGTGCCGGAGAACCGTCCGGGCGACCCGACCGCGGGTGCCGACGGCAAGAAGGGCAACTCG
GTGTTCGCGGCGCCGTCCTTCCTTGGCGGCAAGAACCAGATGCCGATGGCTTACTCGCCGGACACCAAGCTGTTCTACGT
GCCGTCGAACGAGTGGGGCATGGAGATCTGGAACGAGCCCGTGACCTACAAGAAGGGCGCGGCCTACCTGGGCGCCGGCT
TCACGATCAAGACGATCAACGACGAGTACATCGGCGCGATGCGTGCGATCGACCCGAAGACCGGCAAGACCGTCTGGGAA
GTGAAGAACAACGCGCCGCTGTGGGGCGGTGTGCTGACGACGGCCGGCAACCTGGTGTTCTGGGGCACGCCGGAAGGCTT
CCTGAAGGCCGCCGACGCGAAGACCGGCAAGGTCGTCTGGGAATTCCAGACCGGTTCGGGCGTCGTGGCGCCGCCGGTCA
CCTGGCAGCAGGACGGCGAGCAGTACGTCTCGGTCGTTTCCGGCTGGGGCGGCGCCGTGCCGCTGTGGGGTGGCGACGTG
GCCAAGAAGGTCAACTTCCTGGAGCAGGGCGGCACCGTGTGGGTGTTCAAGCTGCCGAAGTGA

Upstream 100 bases:

>100_bases
CCGATCGGTCCGTGGCACGGGCCTTGCCCTCTGGGAGTCAGAACGCGCTTTAGCGGCCATGTCGTGTCGCACGCGTCTCA
CCCCCCGAGGAGACAAAACT

Downstream 100 bases:

>100_bases
ACTGAGCGAGTACCACGCCCGGGATGACCGGGCGCGTTGCACGGCACGGACGCTCGCGCGTCCGTGCCGTTTTTCGTGGC
CGACCGGTACCGTTCTCACG

Product: quinoprotein ethanol dehydrogenase

Products: NA

Alternate protein names: QEDH [H]

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MRLHLLSLLVAAACASVGAQAAGVTDAMIDNDAKTPNDVLSWGIGSQGQRYSPLKQVNTSTVQKLVPAWAFSFGGEKQRG
QQSQPLIHDGKMFVTASYSRIYALDVKTGTKLWKYEHRLPEGIMPCCDVINRGAALYDNLVIFGTLDAQLVALDQKTGDV
VWKEKIDDYAAGYSYTAAPLIAGGLLLTGVSGGEFGIVGRVEARDPKTGKMVWIRPTVEGHMGYKFDKDGNKTEIGISGT
TGKTWPGDMWKSGGAATWLGGTYDAKTGLAYFGTGNPGPWNSHLRPGDNLFSCATVAIDVKTGQIKWHYQTTPHDGWDFD
GVNEFVTFDMDGKRVGGKADRNGFFYVIDAANGKLENAFPFVKKITWATGIDLKTGRPNYVPENRPGDPTAGADGKKGNS
VFAAPSFLGGKNQMPMAYSPDTKLFYVPSNEWGMEIWNEPVTYKKGAAYLGAGFTIKTINDEYIGAMRAIDPKTGKTVWE
VKNNAPLWGGVLTTAGNLVFWGTPEGFLKAADAKTGKVVWEFQTGSGVVAPPVTWQQDGEQYVSVVSGWGGAVPLWGGDV
AKKVNFLEQGGTVWVFKLPK

Sequences:

>Translated_580_residues
MRLHLLSLLVAAACASVGAQAAGVTDAMIDNDAKTPNDVLSWGIGSQGQRYSPLKQVNTSTVQKLVPAWAFSFGGEKQRG
QQSQPLIHDGKMFVTASYSRIYALDVKTGTKLWKYEHRLPEGIMPCCDVINRGAALYDNLVIFGTLDAQLVALDQKTGDV
VWKEKIDDYAAGYSYTAAPLIAGGLLLTGVSGGEFGIVGRVEARDPKTGKMVWIRPTVEGHMGYKFDKDGNKTEIGISGT
TGKTWPGDMWKSGGAATWLGGTYDAKTGLAYFGTGNPGPWNSHLRPGDNLFSCATVAIDVKTGQIKWHYQTTPHDGWDFD
GVNEFVTFDMDGKRVGGKADRNGFFYVIDAANGKLENAFPFVKKITWATGIDLKTGRPNYVPENRPGDPTAGADGKKGNS
VFAAPSFLGGKNQMPMAYSPDTKLFYVPSNEWGMEIWNEPVTYKKGAAYLGAGFTIKTINDEYIGAMRAIDPKTGKTVWE
VKNNAPLWGGVLTTAGNLVFWGTPEGFLKAADAKTGKVVWEFQTGSGVVAPPVTWQQDGEQYVSVVSGWGGAVPLWGGDV
AKKVNFLEQGGTVWVFKLPK
>Mature_580_residues
MRLHLLSLLVAAACASVGAQAAGVTDAMIDNDAKTPNDVLSWGIGSQGQRYSPLKQVNTSTVQKLVPAWAFSFGGEKQRG
QQSQPLIHDGKMFVTASYSRIYALDVKTGTKLWKYEHRLPEGIMPCCDVINRGAALYDNLVIFGTLDAQLVALDQKTGDV
VWKEKIDDYAAGYSYTAAPLIAGGLLLTGVSGGEFGIVGRVEARDPKTGKMVWIRPTVEGHMGYKFDKDGNKTEIGISGT
TGKTWPGDMWKSGGAATWLGGTYDAKTGLAYFGTGNPGPWNSHLRPGDNLFSCATVAIDVKTGQIKWHYQTTPHDGWDFD
GVNEFVTFDMDGKRVGGKADRNGFFYVIDAANGKLENAFPFVKKITWATGIDLKTGRPNYVPENRPGDPTAGADGKKGNS
VFAAPSFLGGKNQMPMAYSPDTKLFYVPSNEWGMEIWNEPVTYKKGAAYLGAGFTIKTINDEYIGAMRAIDPKTGKTVWE
VKNNAPLWGGVLTTAGNLVFWGTPEGFLKAADAKTGKVVWEFQTGSGVVAPPVTWQQDGEQYVSVVSGWGGAVPLWGGDV
AKKVNFLEQGGTVWVFKLPK

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is a very poor substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 62637; Mature: 62637

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLHLLSLLVAAACASVGAQAAGVTDAMIDNDAKTPNDVLSWGIGSQGQRYSPLKQVNTS
CCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHCCCCCCCCCCCHHHHCCHH
TVQKLVPAWAFSFGGEKQRGQQSQPLIHDGKMFVTASYSRIYALDVKTGTKLWKYEHRLP
HHHHHHHHHHHHCCCCHHCCCCCCCEEECCEEEEEEECCEEEEEEECCCCCHHHHHHCCC
EGIMPCCDVINRGAALYDNLVIFGTLDAQLVALDQKTGDVVWKEKIDDYAAGYSYTAAPL
CCHHHHHHHHHCCCHHHCCEEEEEECCEEEEEEECCCCCEEEHHHHHHHHCCCCCCHHHH
IAGGLLLTGVSGGEFGIVGRVEARDPKTGKMVWIRPTVEGHMGYKFDKDGNKTEIGISGT
HHCCEEEEECCCCCEEEEEEEECCCCCCCCEEEEEECCCCCCCEEECCCCCEEEEEEECC
TGKTWPGDMWKSGGAATWLGGTYDAKTGLAYFGTGNPGPWNSHLRPGDNLFSCATVAIDV
CCCCCCCHHHCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEE
KTGQIKWHYQTTPHDGWDFDGVNEFVTFDMDGKRVGGKADRNGFFYVIDAANGKLENAFP
EECEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCH
FVKKITWATGIDLKTGRPNYVPENRPGDPTAGADGKKGNSVFAAPSFLGGKNQMPMAYSP
HHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEECC
DTKLFYVPSNEWGMEIWNEPVTYKKGAAYLGAGFTIKTINDEYIGAMRAIDPKTGKTVWE
CCEEEEEECCCCCHHHCCCCCCCCCCCEEEECCEEEEECCHHHHHHHHCCCCCCCCEEEE
VKNNAPLWGGVLTTAGNLVFWGTPEGFLKAADAKTGKVVWEFQTGSGVVAPPVTWQQDGE
ECCCCCEECCHHHCCCCEEEECCCHHHEEECCCCCCEEEEEEECCCCEECCCCCCCCCCH
QYVSVVSGWGGAVPLWGGDVAKKVNFLEQGGTVWVFKLPK
HHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure
MRLHLLSLLVAAACASVGAQAAGVTDAMIDNDAKTPNDVLSWGIGSQGQRYSPLKQVNTS
CCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCHHHHHCCCCCCCCCCCHHHHCCHH
TVQKLVPAWAFSFGGEKQRGQQSQPLIHDGKMFVTASYSRIYALDVKTGTKLWKYEHRLP
HHHHHHHHHHHHCCCCHHCCCCCCCEEECCEEEEEEECCEEEEEEECCCCCHHHHHHCCC
EGIMPCCDVINRGAALYDNLVIFGTLDAQLVALDQKTGDVVWKEKIDDYAAGYSYTAAPL
CCHHHHHHHHHCCCHHHCCEEEEEECCEEEEEEECCCCCEEEHHHHHHHHCCCCCCHHHH
IAGGLLLTGVSGGEFGIVGRVEARDPKTGKMVWIRPTVEGHMGYKFDKDGNKTEIGISGT
HHCCEEEEECCCCCEEEEEEEECCCCCCCCEEEEEECCCCCCCEEECCCCCEEEEEEECC
TGKTWPGDMWKSGGAATWLGGTYDAKTGLAYFGTGNPGPWNSHLRPGDNLFSCATVAIDV
CCCCCCCHHHCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEE
KTGQIKWHYQTTPHDGWDFDGVNEFVTFDMDGKRVGGKADRNGFFYVIDAANGKLENAFP
EECEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCH
FVKKITWATGIDLKTGRPNYVPENRPGDPTAGADGKKGNSVFAAPSFLGGKNQMPMAYSP
HHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEECC
DTKLFYVPSNEWGMEIWNEPVTYKKGAAYLGAGFTIKTINDEYIGAMRAIDPKTGKTVWE
CCEEEEEECCCCCHHHCCCCCCCCCCCEEEECCEEEEECCHHHHHHHHCCCCCCCCEEEE
VKNNAPLWGGVLTTAGNLVFWGTPEGFLKAADAKTGKVVWEFQTGSGVVAPPVTWQQDGE
ECCCCCEECCHHHCCCCEEEECCCHHHEEECCCCCCEEEEEEECCCCEECCCCCCCCCCH
QYVSVVSGWGGAVPLWGGDVAKKVNFLEQGGTVWVFKLPK
HHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826187; 10984043; 10075429; 10736230 [H]