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The map label for this gene is gltJ [H]

Identifier: 124265637

GI number: 124265637

Start: 483057

End: 483797

Strand: Direct

Name: gltJ [H]

Synonym: Mpe_A0444

Alternate gene names: 124265637

Gene position: 483057-483797 (Clockwise)

Preceding gene: 124265636

Following gene: 124265638

Centisome position: 11.94

GC content: 65.99

Gene sequence:

>741_bases
GTGGCCACATGGGACTGGCAGGTGTTCTGCAAGAACACCCTCGATGGCGAGGTCATCCCCCGCTGCTTCGGCAGCGGCGG
CGACATCACCTATCTCGACTGGATGATCTCGGCCTGGGGCTGGACGCTGTCGGTGGCCCTGCTGGCGCTGCTGGTCGCGC
TGCTGGTCGGCTCGCTGGTCGGCATCCTGCGCACGCTGCCCGACAAGCGGCTGGTGTTCCTGGGCAATGCGTGGACCGAG
ATCTTCCGCAACGTCCCGCTGCTGGTCCAGGTGTTCCTCTGGTACCACGTGATCCCGTCGCTCTTCACCAGCCTGCGCAG
CGTGCCCAGCTTCGTGCTGGTGGTGTTTGCGCTGGGCTTCTTCACCTCGGCGCGCATTGCCGAGCAGGTCAAGGCGGGCA
TCCAGAGCCTGCCGCGCGGCCAGAGCTACGCCGGCCTCGCGATGGGCCTCACGCTGGGCCAGACCTACCGCCATGTGCTG
CTGCCGATGGCGTTCCGCATCGTCATTCCGCCGCTCACCAGCGAGTCGATGAACATCATCAAGAACTCGTCGGTCGCGTT
CGCGGTGAGCATCGCCGAGCTGACGATGTTCGCGATGCAGGCGCAGGAGGAAACCTCGCGCGGGGTCGAGGTCTACCTGG
CGGTGACGGCGCTGTACTTCATCTCGGCCTTCGCCATCAACCGCATCATGCTGGTCGTCGAGGAACGCCTGCGCGTGCCC
GGCATGGCGGGAGGCAAATGA

Upstream 100 bases:

>100_bases
GCCCCGGCTTGAGTCGGGCGCGCGATAAGGGTACAACCCAACCGCGCCGCTCCGTCGGGCGCAGAAAGCGCGCTCGCACA
CCCCAGGAAAGGGAGGCCTC

Downstream 100 bases:

>100_bases
TGAACCCCCACGTCCCTTTGCTCCTTCCCCCCAAGGGGGCTCGGCCTGCCCTTGGGGTGGCCCGGCGGGAGGCCTGAGAT
GCTGAACCTCGATTTTTCCT

Product: putative ABC transporter protein glutamate/aspartate transmembrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MATWDWQVFCKNTLDGEVIPRCFGSGGDITYLDWMISAWGWTLSVALLALLVALLVGSLVGILRTLPDKRLVFLGNAWTE
IFRNVPLLVQVFLWYHVIPSLFTSLRSVPSFVLVVFALGFFTSARIAEQVKAGIQSLPRGQSYAGLAMGLTLGQTYRHVL
LPMAFRIVIPPLTSESMNIIKNSSVAFAVSIAELTMFAMQAQEETSRGVEVYLAVTALYFISAFAINRIMLVVEERLRVP
GMAGGK

Sequences:

>Translated_246_residues
MATWDWQVFCKNTLDGEVIPRCFGSGGDITYLDWMISAWGWTLSVALLALLVALLVGSLVGILRTLPDKRLVFLGNAWTE
IFRNVPLLVQVFLWYHVIPSLFTSLRSVPSFVLVVFALGFFTSARIAEQVKAGIQSLPRGQSYAGLAMGLTLGQTYRHVL
LPMAFRIVIPPLTSESMNIIKNSSVAFAVSIAELTMFAMQAQEETSRGVEVYLAVTALYFISAFAINRIMLVVEERLRVP
GMAGGK
>Mature_245_residues
ATWDWQVFCKNTLDGEVIPRCFGSGGDITYLDWMISAWGWTLSVALLALLVALLVGSLVGILRTLPDKRLVFLGNAWTEI
FRNVPLLVQVFLWYHVIPSLFTSLRSVPSFVLVVFALGFFTSARIAEQVKAGIQSLPRGQSYAGLAMGLTLGQTYRHVLL
PMAFRIVIPPLTSESMNIIKNSSVAFAVSIAELTMFAMQAQEETSRGVEVYLAVTALYFISAFAINRIMLVVEERLRVPG
MAGGK

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786874, Length=254, Percent_Identity=41.7322834645669, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI1788226, Length=213, Percent_Identity=31.4553990610329, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787030, Length=198, Percent_Identity=31.3131313131313, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994930, Length=133, Percent_Identity=36.0902255639098, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1786873, Length=201, Percent_Identity=26.3681592039801, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082239, Length=162, Percent_Identity=27.1604938271605, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787086, Length=221, Percent_Identity=25.7918552036199, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788645, Length=202, Percent_Identity=24.7524752475248, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27156; Mature: 27024

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATWDWQVFCKNTLDGEVIPRCFGSGGDITYLDWMISAWGWTLSVALLALLVALLVGSLV
CCCCCHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GILRTLPDKRLVFLGNAWTEIFRNVPLLVQVFLWYHVIPSLFTSLRSVPSFVLVVFALGF
HHHHHCCCCEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTSARIAEQVKAGIQSLPRGQSYAGLAMGLTLGQTYRHVLLPMAFRIVIPPLTSESMNII
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KNSSVAFAVSIAELTMFAMQAQEETSRGVEVYLAVTALYFISAFAINRIMLVVEERLRVP
HCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GMAGGK
CCCCCC
>Mature Secondary Structure 
ATWDWQVFCKNTLDGEVIPRCFGSGGDITYLDWMISAWGWTLSVALLALLVALLVGSLV
CCCCHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GILRTLPDKRLVFLGNAWTEIFRNVPLLVQVFLWYHVIPSLFTSLRSVPSFVLVVFALGF
HHHHHCCCCEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTSARIAEQVKAGIQSLPRGQSYAGLAMGLTLGQTYRHVLLPMAFRIVIPPLTSESMNII
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KNSSVAFAVSIAELTMFAMQAQEETSRGVEVYLAVTALYFISAFAINRIMLVVEERLRVP
HCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GMAGGK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]