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The map label for this gene is ruvB

Identifier: 124265520

GI number: 124265520

Start: 357634

End: 358701

Strand: Direct

Name: ruvB

Synonym: Mpe_A0327

Alternate gene names: 124265520

Gene position: 357634-358701 (Clockwise)

Preceding gene: 124265519

Following gene: 124265521

Centisome position: 8.84

GC content: 64.33

Gene sequence:

>1068_bases
ATGAGCATCCAGACTGACGATTTCGCTTCGTCCTCGCCGGCCGCACGTCGCGTGGTCAGTACAGCACCGGCGTCACCCAA
TGAGGAGGCGATCGAGCGGGCGCTCCGTCCGAAGGGTCTGGCCGACTACGTGGGTCAGGCCAAGGCCCGTGAGCAGTTGG
AGATCTTCATTGGTGCCGCTCGCAAGCGGTCTGAGGCGCTTGACCACGTCCTTCTGTTTGGCCCTCCTGGCCTAGGGAAG
ACCACGCTCTCGCACATCATCGCGGCCGAACTCGGCGTCAATCTGCGTCAAACCTCGGGCCCGGTGCTCGAGAAGCCCAA
GGACCTGGCGGCAATCCTGACCAATCTCGAGCGCAACGATGTCTTGTTCATCGACGAGATCCACCGTCTGTCCCCGGTGG
TGGAGGAGATCCTCTACCCTGCACTGGAGGACTATCAGATCGACATCATGATCGGCGAGGGGCCGGCCGCCCGTTCGATC
AAGCTCGAGTTGCAGCCCTTCACGCTGATCGGCGCGACGACCCGAGCCGGAATGCTGACGAATCCATTGCGCGATCGCTT
CGGCATCGTGGCGCGCCTGGAGTTCTATTCGGTCGAGGAGTTGGCCCGCATCGTCACCCGCTCCGCGGGGCTGTTGCAAG
TGCCGACCGATACGGCGGGCGGGCTGGAGATCGCCAAGCGCTCACGAGGAACGCCACGCATCGCCAATCGCCTGCTTCGA
CGAGTGCGCGACTACGCACAGGTCAAGGGCGACGGCCGCATCGATGCCGCGATCGCCGACAAGGCGCTCGCCATGCTCGA
CGTCGATCCCCAGGGCTTCGATGTGATGGACCGCAAGCTGCTCGAGGCGGTGATTCATCGCTTCGATGGTGGACCGGTCG
GCCTCGACAATGTCGCGGCGGCGATCGGTGAGGAGTCCGGCACCATCGAGGACGTGATCGAGCCCTATCTGATCCAGCAA
GGCTACCTTCAGCGCACGCCGCGCGGTCGCATCGCAACGGCGGCGGCGTACCGCCATCTTGGCGTGTTGCCGCCGACGAC
CTCCGGCAGCGAGTTGTTCGACGCATAA

Upstream 100 bases:

>100_bases
GCGTTTTTGCTTTTGGGCGTCGATATGAATCGTCAAGATTCCTCTGCGCTGTTTTCGATGAGGCGTCGCACTGGCATGGC
GTGTCCCGCACAATTGCAGC

Downstream 100 bases:

>100_bases
CAACAGGCTCTACCGACCCGCGATATCCGTCAGGGGCGGTCCTTCCCCAACGAGACCTTGCGCCTCGTCTGCCGACGAAG
TGGCCAATGTCCATGAACAG

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSIQTDDFASSSPAARRVVSTAPASPNEEAIERALRPKGLADYVGQAKAREQLEIFIGAARKRSEALDHVLLFGPPGLGK
TTLSHIIAAELGVNLRQTSGPVLEKPKDLAAILTNLERNDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSI
KLELQPFTLIGATTRAGMLTNPLRDRFGIVARLEFYSVEELARIVTRSAGLLQVPTDTAGGLEIAKRSRGTPRIANRLLR
RVRDYAQVKGDGRIDAAIADKALAMLDVDPQGFDVMDRKLLEAVIHRFDGGPVGLDNVAAAIGEESGTIEDVIEPYLIQQ
GYLQRTPRGRIATAAAYRHLGVLPPTTSGSELFDA

Sequences:

>Translated_355_residues
MSIQTDDFASSSPAARRVVSTAPASPNEEAIERALRPKGLADYVGQAKAREQLEIFIGAARKRSEALDHVLLFGPPGLGK
TTLSHIIAAELGVNLRQTSGPVLEKPKDLAAILTNLERNDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSI
KLELQPFTLIGATTRAGMLTNPLRDRFGIVARLEFYSVEELARIVTRSAGLLQVPTDTAGGLEIAKRSRGTPRIANRLLR
RVRDYAQVKGDGRIDAAIADKALAMLDVDPQGFDVMDRKLLEAVIHRFDGGPVGLDNVAAAIGEESGTIEDVIEPYLIQQ
GYLQRTPRGRIATAAAYRHLGVLPPTTSGSELFDA
>Mature_354_residues
SIQTDDFASSSPAARRVVSTAPASPNEEAIERALRPKGLADYVGQAKAREQLEIFIGAARKRSEALDHVLLFGPPGLGKT
TLSHIIAAELGVNLRQTSGPVLEKPKDLAAILTNLERNDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIK
LELQPFTLIGATTRAGMLTNPLRDRFGIVARLEFYSVEELARIVTRSAGLLQVPTDTAGGLEIAKRSRGTPRIANRLLRR
VRDYAQVKGDGRIDAAIADKALAMLDVDPQGFDVMDRKLLEAVIHRFDGGPVGLDNVAAAIGEESGTIEDVIEPYLIQQG
YLQRTPRGRIATAAAYRHLGVLPPTTSGSELFDA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=331, Percent_Identity=70.0906344410876, Blast_Score=463, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_METPP (A2SCK0)

Other databases:

- EMBL:   CP000555
- RefSeq:   YP_001019524.1
- ProteinModelPortal:   A2SCK0
- SMR:   A2SCK0
- STRING:   A2SCK0
- GeneID:   4786877
- GenomeReviews:   CP000555_GR
- KEGG:   mpt:Mpe_A0327
- NMPDR:   fig|279263.3.peg.3576
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   A2SCK0
- ProtClustDB:   PRK00080
- BioCyc:   MPET420662:MPE_A0327-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 38515; Mature: 38383

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQTDDFASSSPAARRVVSTAPASPNEEAIERALRPKGLADYVGQAKAREQLEIFIGAA
CCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RKRSEALDHVLLFGPPGLGKTTLSHIIAAELGVNLRQTSGPVLEKPKDLAAILTNLERND
HHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHCCCCCC
VLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKLELQPFTLIGATTRAGMLT
EEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCEEEEECCHHCCHHH
NPLRDRFGIVARLEFYSVEELARIVTRSAGLLQVPTDTAGGLEIAKRSRGTPRIANRLLR
HHHHHHHCCEEEEHHHCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHCCCCHHHHHHHHH
RVRDYAQVKGDGRIDAAIADKALAMLDVDPQGFDVMDRKLLEAVIHRFDGGPVGLDNVAA
HHHHHHHHCCCCCEEHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
AIGEESGTIEDVIEPYLIQQGYLQRTPRGRIATAAAYRHLGVLPPTTSGSELFDA
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
SIQTDDFASSSPAARRVVSTAPASPNEEAIERALRPKGLADYVGQAKAREQLEIFIGAA
CCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RKRSEALDHVLLFGPPGLGKTTLSHIIAAELGVNLRQTSGPVLEKPKDLAAILTNLERND
HHHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHCCCCCC
VLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKLELQPFTLIGATTRAGMLT
EEEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEECCEEEEECCHHCCHHH
NPLRDRFGIVARLEFYSVEELARIVTRSAGLLQVPTDTAGGLEIAKRSRGTPRIANRLLR
HHHHHHHCCEEEEHHHCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHCCCCHHHHHHHHH
RVRDYAQVKGDGRIDAAIADKALAMLDVDPQGFDVMDRKLLEAVIHRFDGGPVGLDNVAA
HHHHHHHHCCCCCEEHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
AIGEESGTIEDVIEPYLIQQGYLQRTPRGRIATAAAYRHLGVLPPTTSGSELFDA
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA