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The map label for this gene is ywlC [H]

Identifier: 124265490

GI number: 124265490

Start: 321833

End: 322840

Strand: Direct

Name: ywlC [H]

Synonym: Mpe_A0297

Alternate gene names: 124265490

Gene position: 321833-322840 (Clockwise)

Preceding gene: 124265489

Following gene: 124265491

Centisome position: 7.96

GC content: 74.7

Gene sequence:

>1008_bases
ATGCCGCGGCTCGACGGTCATGCCCCCGAGGCGGTCGCCGAAGCCGCCCGGCTGCTCGCGGCCGGACACCTCGTCGCCTT
TCCTACCGAAACGGTCTACGGCCTCGGCGCGCGAGCCGACGACGATGCGGCCGTCGCGAAGATTTTCGCCGCCAAGGGCC
GGCCGACCGACCATCCGCTGATCGTGCACGTGGCCGATGCCGCCGGAGCGCAGGCCTTTGCGGCCGAACTGCCGCCGCTG
GCGCAGCGGCTGATCGCCGCCTTCTGGCCCGGGACGCTGACCGTGATCGTGTCGCGCCGCGCCGGCGTGGCTGCTGCCGC
TTCTGGTGGGCAGCCCAGCATCGGCCTGCGCTGCCCCTCGCATCCGGTGGCCCAGGCGCTGCTGCGCTCGGCTGCAGCGC
TCGGCGTGCCGGGCGTCGCCGGCCCCAGCGCCAACCGCTATGGCCGCGTCAGCCCCACGCGCGCGGCGCACGTCGAGGGC
GAGTTCGATGCGGCGCTCGTGGTGCTCGACGGTGGCGATTGCGAAGTCGGCATCGAGTCCACCATCGTCGACTGCACGCG
CGGCCATCCGGTGCTGCTGCGCCCCGGCGTACTGCCGCGCGAGCGCATCGAGGCGGCAGCCGGCGAGCGATTGCTCGATG
CCGCCGACGCGCTGGCCGGCAGCGCGCCGCGCGCGCCCGGCACGCTGGCCTCGCACTACGCCCCGCGCGCCACGCTGCGC
CTGATGCCGGCCACCGCGCTGCGCACGGCGCTCGAGGTGCTGCCGACCGATGCCCTGCCGAAGCGGGGTGGCAGCAGGCT
GGCGGTATATTCGCGCAGCGTGTCACCGCCTTCGCGCCTCACAGCGCGGCGGATGCCGGACGATCCGGCAGCGGCGGCGC
ACGAGTTGTTTTCCGTGCTGCGCGAACTCGACGACGAGGGCGTGCAGTTGATCTGGGTCGAAGAGCCGCCCGCCGGTCCC
GCCTGGGAGGGCGTCCGGGACCGCCTGCAACGCGCGGCCGCGCCCTGA

Upstream 100 bases:

>100_bases
AGATGGGTCACCTGACGCTGACTGCCGACACGCCCGAGGCAGCGCGCGCGACCGCGCTGCGGGCGGCGGAGCGGCTCGGC
CTGCCGGCGTTCTGAAGAAC

Downstream 100 bases:

>100_bases
GCGCGCCGACCCTCACCCCCTGGCCTGTGGAGTTGGAGTGAGCATGACTGTTGGGAAAGCTTGCGTGCGCGGACTGTCGC
GCGCGCTGCGGGTGTCGATG

Product: translation factor SUA5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPRLDGHAPEAVAEAARLLAAGHLVAFPTETVYGLGARADDDAAVAKIFAAKGRPTDHPLIVHVADAAGAQAFAAELPPL
AQRLIAAFWPGTLTVIVSRRAGVAAAASGGQPSIGLRCPSHPVAQALLRSAAALGVPGVAGPSANRYGRVSPTRAAHVEG
EFDAALVVLDGGDCEVGIESTIVDCTRGHPVLLRPGVLPRERIEAAAGERLLDAADALAGSAPRAPGTLASHYAPRATLR
LMPATALRTALEVLPTDALPKRGGSRLAVYSRSVSPPSRLTARRMPDDPAAAAHELFSVLRELDDEGVQLIWVEEPPAGP
AWEGVRDRLQRAAAP

Sequences:

>Translated_335_residues
MPRLDGHAPEAVAEAARLLAAGHLVAFPTETVYGLGARADDDAAVAKIFAAKGRPTDHPLIVHVADAAGAQAFAAELPPL
AQRLIAAFWPGTLTVIVSRRAGVAAAASGGQPSIGLRCPSHPVAQALLRSAAALGVPGVAGPSANRYGRVSPTRAAHVEG
EFDAALVVLDGGDCEVGIESTIVDCTRGHPVLLRPGVLPRERIEAAAGERLLDAADALAGSAPRAPGTLASHYAPRATLR
LMPATALRTALEVLPTDALPKRGGSRLAVYSRSVSPPSRLTARRMPDDPAAAAHELFSVLRELDDEGVQLIWVEEPPAGP
AWEGVRDRLQRAAAP
>Mature_334_residues
PRLDGHAPEAVAEAARLLAAGHLVAFPTETVYGLGARADDDAAVAKIFAAKGRPTDHPLIVHVADAAGAQAFAAELPPLA
QRLIAAFWPGTLTVIVSRRAGVAAAASGGQPSIGLRCPSHPVAQALLRSAAALGVPGVAGPSANRYGRVSPTRAAHVEGE
FDAALVVLDGGDCEVGIESTIVDCTRGHPVLLRPGVLPRERIEAAAGERLLDAADALAGSAPRAPGTLASHYAPRATLRL
MPATALRTALEVLPTDALPKRGGSRLAVYSRSVSPPSRLTARRMPDDPAAAAHELFSVLRELDDEGVQLIWVEEPPAGPA
WEGVRDRLQRAAAP

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=165, Percent_Identity=30.9090909090909, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321269, Length=385, Percent_Identity=31.6883116883117, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 34631; Mature: 34500

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLDGHAPEAVAEAARLLAAGHLVAFPTETVYGLGARADDDAAVAKIFAAKGRPTDHPL
CCCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCE
IVHVADAAGAQAFAAELPPLAQRLIAAFWPGTLTVIVSRRAGVAAAASGGQPSIGLRCPS
EEEECCCCCCHHHHHHCCHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCCCCC
HPVAQALLRSAAALGVPGVAGPSANRYGRVSPTRAAHVEGEFDAALVVLDGGDCEVGIES
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCCCCH
TIVDCTRGHPVLLRPGVLPRERIEAAAGERLLDAADALAGSAPRAPGTLASHYAPRATLR
HEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCEEE
LMPATALRTALEVLPTDALPKRGGSRLAVYSRSVSPPSRLTARRMPDDPAAAAHELFSVL
ECCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHH
RELDDEGVQLIWVEEPPAGPAWEGVRDRLQRAAAP
HHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PRLDGHAPEAVAEAARLLAAGHLVAFPTETVYGLGARADDDAAVAKIFAAKGRPTDHPL
CCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCE
IVHVADAAGAQAFAAELPPLAQRLIAAFWPGTLTVIVSRRAGVAAAASGGQPSIGLRCPS
EEEECCCCCCHHHHHHCCHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCCCCC
HPVAQALLRSAAALGVPGVAGPSANRYGRVSPTRAAHVEGEFDAALVVLDGGDCEVGIES
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCCCCH
TIVDCTRGHPVLLRPGVLPRERIEAAAGERLLDAADALAGSAPRAPGTLASHYAPRATLR
HEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCEEE
LMPATALRTALEVLPTDALPKRGGSRLAVYSRSVSPPSRLTARRMPDDPAAAAHELFSVL
ECCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHH
RELDDEGVQLIWVEEPPAGPAWEGVRDRLQRAAAP
HHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]