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The map label for this gene is queC

Identifier: 124265463

GI number: 124265463

Start: 293131

End: 293838

Strand: Direct

Name: queC

Synonym: Mpe_A0270

Alternate gene names: 124265463

Gene position: 293131-293838 (Clockwise)

Preceding gene: 124265462

Following gene: 124265464

Centisome position: 7.25

GC content: 70.76

Gene sequence:

>708_bases
ATGAGCCTCGATCCGCGCGGCGCCCTCGTCCTGTTCTCCGGCGGCCAGGACTCGACCGCCTGCCTGGCCTGGGCGCTGGA
GCACCACGCGCACGTGGAGACCATCGGCTTCGACTACGGCCAGCGCCACGTCGTCGAACTCGAATGCCGCGTGCAGGTGC
GCGAGGCGATCGCGCGGTCGTTCCCGCTGTGGGCCGGCCGGCTGGCCAACGACCACGTGCTCGACCTCGGTCTGCTCGGC
CAGATCTCCGACACCGCGCTGACCTCGGCGCGCGCGATCGAGATGCAGGCCAACGGCCTGCCGAGCACCTTCGTGCCGGG
GCGCAACCTGCTGTTCCTCGGCTTCGCGGCCACCGTGGCCTACCGGCGCAACCTCAGCGTGCTGGTCGGCGGCATGTGCG
AGACCGACTACTCCGGCTACCCTGACTGCCGCGACAACACACTCAAGGCGCTGCAGGTCGCGCTCAGCCTGGGCATGGCC
ACGCCGATGACGATAGAAACGCCGCTGATGTGGCTCGACAAGGCCCGGACCTGGGCGCTCACCGATCGCCTGGGCGGCCG
CGCCTTGAACGAGCTGATCCTCGAGCACACCCACAGCTGCTACCTCGGCGACCGCAGCGTGCGCCACGCCTGGGGCTACG
GCTGCAATGCCTGCCCGGCCTGCGAGCTGCGGCGCAAGGGCTACGAGGCCTGGTGCGCCGGCGCCTGA

Upstream 100 bases:

>100_bases
ACCGACAAGTTCCACGCCCGCGGGCCGGTGGGCCTCGAGGGGCTCACCTCGATGAAGTGGGTGGTGTTCGGGCAGGGCGA
GGTCCGCACCTGATCGGCGC

Downstream 100 bases:

>100_bases
CGACGCACGCCGCGGCGGCCGCGACGGCTGGCGTAGAGTCGGCAGCCATGCCGGCCCCCGCCCGTTCCCGATGAGCACGA
CGCGCACCGTCCTCCTGGCG

Product: hypothetical protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSLDPRGALVLFSGGQDSTACLAWALEHHAHVETIGFDYGQRHVVELECRVQVREAIARSFPLWAGRLANDHVLDLGLLG
QISDTALTSARAIEMQANGLPSTFVPGRNLLFLGFAATVAYRRNLSVLVGGMCETDYSGYPDCRDNTLKALQVALSLGMA
TPMTIETPLMWLDKARTWALTDRLGGRALNELILEHTHSCYLGDRSVRHAWGYGCNACPACELRRKGYEAWCAGA

Sequences:

>Translated_235_residues
MSLDPRGALVLFSGGQDSTACLAWALEHHAHVETIGFDYGQRHVVELECRVQVREAIARSFPLWAGRLANDHVLDLGLLG
QISDTALTSARAIEMQANGLPSTFVPGRNLLFLGFAATVAYRRNLSVLVGGMCETDYSGYPDCRDNTLKALQVALSLGMA
TPMTIETPLMWLDKARTWALTDRLGGRALNELILEHTHSCYLGDRSVRHAWGYGCNACPACELRRKGYEAWCAGA
>Mature_234_residues
SLDPRGALVLFSGGQDSTACLAWALEHHAHVETIGFDYGQRHVVELECRVQVREAIARSFPLWAGRLANDHVLDLGLLGQ
ISDTALTSARAIEMQANGLPSTFVPGRNLLFLGFAATVAYRRNLSVLVGGMCETDYSGYPDCRDNTLKALQVALSLGMAT
PMTIETPLMWLDKARTWALTDRLGGRALNELILEHTHSCYLGDRSVRHAWGYGCNACPACELRRKGYEAWCAGA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=232, Percent_Identity=45.2586206896552, Blast_Score=189, Evalue=9e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_METPP (A2SCE3)

Other databases:

- EMBL:   CP000555
- RefSeq:   YP_001019467.1
- STRING:   A2SCE3
- GeneID:   4786939
- GenomeReviews:   CP000555_GR
- KEGG:   mpt:Mpe_A0270
- NMPDR:   fig|279263.3.peg.184
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- PhylomeDB:   A2SCE3
- ProtClustDB:   CLSK864419
- BioCyc:   MPET420662:MPE_A0270-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25739; Mature: 25608

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDPRGALVLFSGGQDSTACLAWALEHHAHVETIGFDYGQRHVVELECRVQVREAIARS
CCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHH
FPLWAGRLANDHVLDLGLLGQISDTALTSARAIEMQANGLPSTFVPGRNLLFLGFAATVA
CCCHHCCCCCCCEEEEHHCCCCCHHHHHHHEEEEEECCCCCCCCCCCCCEEEEHHHHHHH
YRRNLSVLVGGMCETDYSGYPDCRDNTLKALQVALSLGMATPMTIETPLMWLDKARTWAL
HHCCCEEEECCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCHHHHHCCCEEEE
TDRLGGRALNELILEHTHSCYLGDRSVRHAWGYGCNACPACELRRKGYEAWCAGA
HHHHCHHHHHHHHHHHCCCEEECCCHHHHHCCCCCCCCCHHHHHHCCCCEEECCC
>Mature Secondary Structure 
SLDPRGALVLFSGGQDSTACLAWALEHHAHVETIGFDYGQRHVVELECRVQVREAIARS
CCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHH
FPLWAGRLANDHVLDLGLLGQISDTALTSARAIEMQANGLPSTFVPGRNLLFLGFAATVA
CCCHHCCCCCCCEEEEHHCCCCCHHHHHHHEEEEEECCCCCCCCCCCCCEEEEHHHHHHH
YRRNLSVLVGGMCETDYSGYPDCRDNTLKALQVALSLGMATPMTIETPLMWLDKARTWAL
HHCCCEEEECCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCHHHHHCCCEEEE
TDRLGGRALNELILEHTHSCYLGDRSVRHAWGYGCNACPACELRRKGYEAWCAGA
HHHHCHHHHHHHHHHHCCCEEECCCHHHHHCCCCCCCCCHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA