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The map label for this gene is gapA [H]

Identifier: 124265453

GI number: 124265453

Start: 281565

End: 282581

Strand: Direct

Name: gapA [H]

Synonym: Mpe_A0260

Alternate gene names: 124265453

Gene position: 281565-282581 (Clockwise)

Preceding gene: 124265452

Following gene: 124265454

Centisome position: 6.96

GC content: 65.19

Gene sequence:

>1017_bases
ATGACCATCAAAGTTGCCATCAATGGCTACGGCCGCATCGGCCGCAACGTGCTCCGCGCCCACTACGAGGGCGGCAAGAA
GCACGACATCCAGATCGTCGCGATCAACGATCTGGGCGACCCGAAGACCAACGCCCACCTGACGCAGTACGACACCGCGC
ATGGCAGGTTCCCAGGCACGGTCAGCGTCGACGGCGACTACATGGTCATCAACGGCGACAAGATCCGCGTGCTGGCCAAC
CGCAACCCGGCCGAGCTGCCTTGGGGCGAGCTCGGCGTGGACGTGGTGATGGAGTGCACCGGCTTCTTCACGACCAAGGA
AAAGGCCTCGGCGCACCTGAAGGGCGGCGCCAAGAAGGTCATCATCTCGGCGCCGGGCGGCAAGGACGTGGACGCGACCA
TCGTGTTCGGTGTCAACCACGGCGTGCTGAAGGCCACCGACACGGTGATCAGCAACGCCAGCTGCACCACCAACTGCCTG
GCGCCGCTGGTCAAGCCACTGCACGAGAAGATCGGCCTGGAGTCGGGCCTGATGACCACCATCCACGCTTACACCAACGA
CCAGGTGCTGACCGACGTGTACCACGAGGACCTGCGCCGCGCGCGCAGCGCCACGCAGTCGATGATCCCCACCAAGACCG
GCGCCGCCGCTGCGGTGGGCCTGGTGCTGCCCGAACTGAACGGCAAGCTCGATGGCTTCGCGATCCGCGTGCCGACCATC
AACGTGTCGGTGGTCGACCTGACCTTCACCGCCAAGCGCGCCACGACGCTCGAGGAGGTCAACGCCGTGCTGAAGGCCGC
GGCCGAGGGCGAGCTCAAGGGCATCCTGGCCTACAACACCGCGCCTCTGGTGAGCGTGGACTTCAACCACGACCCGGCGT
CCAGCACCTTCGACTCGACCCAGACCCGCGTTTCGCCGGACGGCAAGCTCGTCAAGGTGCTGAGCTGGTATGACAACGAG
TGGGGTTTCAGCAATCGCATGCTGGACACCACCGTAGCGCTGATGGCTGCCAAGTGA

Upstream 100 bases:

>100_bases
GGCCGGATGTCGGGGCCGGCGCGGCGGCGCGGGGCGTTTTGTCGTCGAATGCTGGCCTGAATGAATCCGGATTGAACCGA
AGCTGAGGAAGACCCATACC

Downstream 100 bases:

>100_bases
TCACGGCGCTGCGCAGGCCCCCTGTCAGACAAAGGCCCTTTGGGGCCTTTTTCGTGGGCTGGCTTCGCACCATCGGGTAA
AGCTCTGTCAACGCAGGCCG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTIKVAINGYGRIGRNVLRAHYEGGKKHDIQIVAINDLGDPKTNAHLTQYDTAHGRFPGTVSVDGDYMVINGDKIRVLAN
RNPAELPWGELGVDVVMECTGFFTTKEKASAHLKGGAKKVIISAPGGKDVDATIVFGVNHGVLKATDTVISNASCTTNCL
APLVKPLHEKIGLESGLMTTIHAYTNDQVLTDVYHEDLRRARSATQSMIPTKTGAAAAVGLVLPELNGKLDGFAIRVPTI
NVSVVDLTFTAKRATTLEEVNAVLKAAAEGELKGILAYNTAPLVSVDFNHDPASSTFDSTQTRVSPDGKLVKVLSWYDNE
WGFSNRMLDTTVALMAAK

Sequences:

>Translated_338_residues
MTIKVAINGYGRIGRNVLRAHYEGGKKHDIQIVAINDLGDPKTNAHLTQYDTAHGRFPGTVSVDGDYMVINGDKIRVLAN
RNPAELPWGELGVDVVMECTGFFTTKEKASAHLKGGAKKVIISAPGGKDVDATIVFGVNHGVLKATDTVISNASCTTNCL
APLVKPLHEKIGLESGLMTTIHAYTNDQVLTDVYHEDLRRARSATQSMIPTKTGAAAAVGLVLPELNGKLDGFAIRVPTI
NVSVVDLTFTAKRATTLEEVNAVLKAAAEGELKGILAYNTAPLVSVDFNHDPASSTFDSTQTRVSPDGKLVKVLSWYDNE
WGFSNRMLDTTVALMAAK
>Mature_337_residues
TIKVAINGYGRIGRNVLRAHYEGGKKHDIQIVAINDLGDPKTNAHLTQYDTAHGRFPGTVSVDGDYMVINGDKIRVLANR
NPAELPWGELGVDVVMECTGFFTTKEKASAHLKGGAKKVIISAPGGKDVDATIVFGVNHGVLKATDTVISNASCTTNCLA
PLVKPLHEKIGLESGLMTTIHAYTNDQVLTDVYHEDLRRARSATQSMIPTKTGAAAAVGLVLPELNGKLDGFAIRVPTIN
VSVVDLTFTAKRATTLEEVNAVLKAAAEGELKGILAYNTAPLVSVDFNHDPASSTFDSTQTRVSPDGKLVKVLSWYDNEW
GFSNRMLDTTVALMAAK

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=339, Percent_Identity=50.7374631268437, Blast_Score=312, Evalue=3e-85,
Organism=Homo sapiens, GI7657116, Length=331, Percent_Identity=43.8066465256798, Blast_Score=263, Evalue=1e-70,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=52.9940119760479, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI1788079, Length=330, Percent_Identity=53.030303030303, Blast_Score=332, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI17534679, Length=334, Percent_Identity=52.3952095808383, Blast_Score=313, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI17534677, Length=334, Percent_Identity=51.7964071856287, Blast_Score=311, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI32566163, Length=334, Percent_Identity=52.3952095808383, Blast_Score=306, Evalue=8e-84,
Organism=Caenorhabditis elegans, GI17568413, Length=334, Percent_Identity=52.3952095808383, Blast_Score=306, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6322409, Length=330, Percent_Identity=47.5757575757576, Blast_Score=299, Evalue=4e-82,
Organism=Saccharomyces cerevisiae, GI6322468, Length=330, Percent_Identity=46.3636363636364, Blast_Score=296, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=46.969696969697, Blast_Score=293, Evalue=2e-80,
Organism=Drosophila melanogaster, GI17933600, Length=329, Percent_Identity=50.1519756838906, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI18110149, Length=329, Percent_Identity=50.1519756838906, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI85725000, Length=329, Percent_Identity=50.1519756838906, Blast_Score=297, Evalue=8e-81,
Organism=Drosophila melanogaster, GI22023983, Length=329, Percent_Identity=50.1519756838906, Blast_Score=297, Evalue=8e-81,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=46.6463414634146, Blast_Score=281, Evalue=4e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36213; Mature: 36082

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVAINGYGRIGRNVLRAHYEGGKKHDIQIVAINDLGDPKTNAHLTQYDTAHGRFPGT
CEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCCCE
VSVDGDYMVINGDKIRVLANRNPAELPWGELGVDVVMECTGFFTTKEKASAHLKGGAKKV
EEECCCEEEEECCEEEEEECCCCCCCCCCCCCHHHEEECCCCEEECHHHHHHCCCCCEEE
IISAPGGKDVDATIVFGVNHGVLKATDTVISNASCTTNCLAPLVKPLHEKIGLESGLMTT
EEECCCCCCCCEEEEEECCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
IHAYTNDQVLTDVYHEDLRRARSATQSMIPTKTGAAAAVGLVLPELNGKLDGFAIRVPTI
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEEECCCCCCCCEEEEEEEE
NVSVVDLTFTAKRATTLEEVNAVLKAAAEGELKGILAYNTAPLVSVDFNHDPASSTFDST
EEEEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
QTRVSPDGKLVKVLSWYDNEWGFSNRMLDTTVALMAAK
CEEECCCCCEEEEEEEECCCCCCCCCHHHHEEEEEECC
>Mature Secondary Structure 
TIKVAINGYGRIGRNVLRAHYEGGKKHDIQIVAINDLGDPKTNAHLTQYDTAHGRFPGT
EEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCCCE
VSVDGDYMVINGDKIRVLANRNPAELPWGELGVDVVMECTGFFTTKEKASAHLKGGAKKV
EEECCCEEEEECCEEEEEECCCCCCCCCCCCCHHHEEECCCCEEECHHHHHHCCCCCEEE
IISAPGGKDVDATIVFGVNHGVLKATDTVISNASCTTNCLAPLVKPLHEKIGLESGLMTT
EEECCCCCCCCEEEEEECCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
IHAYTNDQVLTDVYHEDLRRARSATQSMIPTKTGAAAAVGLVLPELNGKLDGFAIRVPTI
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEEECCCCCCCCEEEEEEEE
NVSVVDLTFTAKRATTLEEVNAVLKAAAEGELKGILAYNTAPLVSVDFNHDPASSTFDST
EEEEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
QTRVSPDGKLVKVLSWYDNEWGFSNRMLDTTVALMAAK
CEEECCCCCEEEEEEEECCCCCCCCCHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7763137 [H]