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The map label for this gene is paaJ [C]

Identifier: 124265371

GI number: 124265371

Start: 193515

End: 194702

Strand: Direct

Name: paaJ [C]

Synonym: Mpe_A0178

Alternate gene names: 124265371

Gene position: 193515-194702 (Clockwise)

Preceding gene: 124265370

Following gene: 124265372

Centisome position: 4.79

GC content: 71.38

Gene sequence:

>1188_bases
ATGGCCAACAGAGTCTGCATTGCCGGCGTGGGCATGATCGCCTTCGCCAAGCCCGGCGCCAGCGAGCCCTATCACCTGAT
GGCCGCGCGGGCCGGTCGCCAGGCCCTGGCCGACGCCGGCATCGGCTACGACGCGCTGCAGCAGGCCTACGTGGGCTATG
TCTATGGCGACTCCACGAGCGGCCAGAAGGCGGTCTACGAGCTCGGCATGACCGGCATCCCGGTGATCAACGTCAACAAC
AACTGCTCGACCGGCTCGACCGCGCTGTTCCTGGCGCGCCAAGCGGTGGAGAGCGGCGCCGCCGACTGTGTGCTGGCGCT
CGGCTTCGAGCAGATGAAGCCCGGCGCGCTCGGCACGGTGTTCGACGACCGGCCCAGCCCCTTCGAGGACTTCGACCGCG
AGGCCGAGGCCTTGGTGGGCATGCCGGAGCTGCCGCTCGCGCTGCGCTACTTCGGCGGGGCCGGCCTCGGCCACATGCAG
AAGTACGGCACGCCGCTGGAGGCCTTCGCCCGGATCCGCGCCAAGGCCAGCCGCCACGCCGCGCGCAACCCGCTGGCGCT
GCTGCGCAAGGAGCTCAGCACCGAGGACGTGATGAACGCGCCCATGCTCTGGCCCGGCGTGATGACGCGCCTGATGGCCT
GCCCGCCCACTTGCGGCGCGGCGGCGGCGGTGCTCGTCTCCGAGGCCTACGCCAGGAAGAACGGCCTGCGCACCGACGTG
GCGATCCGCGCCCAGGCCATGACCACCGACCGGCCCGACACCTTCGACAGCCGCGACATGATGAAGGTGGTGGGGGCCGG
CATGAGCCGTGCCGCTGCGCAGAGCGTCTACGAGCAGGCCGGGATCGGTCCCGAGGATCTGGACGTGGTGGAACTGCACG
ACTGCTTCGCGCACAACGAGCTGATCACCTACGAGGCGCTCGGCCTGTGCCCCGAGGGCGGCGCCGCCGCCTTCATCGAC
GCCGGCGACAACACCTACGGCGGTCGCGTGGTCACCAACCCCTCGGGCGGCCTGCTCTCCAAGGGCCATCCGCTCGGCGC
CACCGGCCTGGCGCAGTGCTACGAGCTGACCCACCAGCTGCGCGGCACGGCCGAGCAGCGCCAGGTCGACGGCGCGCGCG
TCGCGCTGCAGCACAACCTGGGGCTGGGCGGGGCGTGCGTCGTGACCTTGTACGAAGCGACCGCCTGA

Upstream 100 bases:

>100_bases
GTCGGCAAGGTCTTGAAGAAGGACATCCGTGCCTCGTTGCTGAAGCCTGCAGAATCGAGTTGAGCTGCCTTCCAGCCACC
GCACCCATCGGAGAGCCGCC

Downstream 100 bases:

>100_bases
GTCTGCAGGCGGCGCGGCGCCGGCGCTGAAGACGGGCGGCTGCCCCTGGCGCGGCCGTGCGCCGGGATACTCCGGCCATG
CTGCGCCGCTTCGTCACCGA

Product: lipid-transfer protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MANRVCIAGVGMIAFAKPGASEPYHLMAARAGRQALADAGIGYDALQQAYVGYVYGDSTSGQKAVYELGMTGIPVINVNN
NCSTGSTALFLARQAVESGAADCVLALGFEQMKPGALGTVFDDRPSPFEDFDREAEALVGMPELPLALRYFGGAGLGHMQ
KYGTPLEAFARIRAKASRHAARNPLALLRKELSTEDVMNAPMLWPGVMTRLMACPPTCGAAAAVLVSEAYARKNGLRTDV
AIRAQAMTTDRPDTFDSRDMMKVVGAGMSRAAAQSVYEQAGIGPEDLDVVELHDCFAHNELITYEALGLCPEGGAAAFID
AGDNTYGGRVVTNPSGGLLSKGHPLGATGLAQCYELTHQLRGTAEQRQVDGARVALQHNLGLGGACVVTLYEATA

Sequences:

>Translated_395_residues
MANRVCIAGVGMIAFAKPGASEPYHLMAARAGRQALADAGIGYDALQQAYVGYVYGDSTSGQKAVYELGMTGIPVINVNN
NCSTGSTALFLARQAVESGAADCVLALGFEQMKPGALGTVFDDRPSPFEDFDREAEALVGMPELPLALRYFGGAGLGHMQ
KYGTPLEAFARIRAKASRHAARNPLALLRKELSTEDVMNAPMLWPGVMTRLMACPPTCGAAAAVLVSEAYARKNGLRTDV
AIRAQAMTTDRPDTFDSRDMMKVVGAGMSRAAAQSVYEQAGIGPEDLDVVELHDCFAHNELITYEALGLCPEGGAAAFID
AGDNTYGGRVVTNPSGGLLSKGHPLGATGLAQCYELTHQLRGTAEQRQVDGARVALQHNLGLGGACVVTLYEATA
>Mature_394_residues
ANRVCIAGVGMIAFAKPGASEPYHLMAARAGRQALADAGIGYDALQQAYVGYVYGDSTSGQKAVYELGMTGIPVINVNNN
CSTGSTALFLARQAVESGAADCVLALGFEQMKPGALGTVFDDRPSPFEDFDREAEALVGMPELPLALRYFGGAGLGHMQK
YGTPLEAFARIRAKASRHAARNPLALLRKELSTEDVMNAPMLWPGVMTRLMACPPTCGAAAAVLVSEAYARKNGLRTDVA
IRAQAMTTDRPDTFDSRDMMKVVGAGMSRAAAQSVYEQAGIGPEDLDVVELHDCFAHNELITYEALGLCPEGGAAAFIDA
GDNTYGGRVVTNPSGGLLSKGHPLGATGLAQCYELTHQLRGTAEQRQVDGARVALQHNLGLGGACVVTLYEATA

Specific function: Thiolytic Cleavage Of Beta-Ketoadipyl-CoA To Succinate And Acetyl-CoA (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=396, Percent_Identity=56.5656565656566, Blast_Score=425, Evalue=1e-119,
Organism=Homo sapiens, GI302344760, Length=396, Percent_Identity=52.7777777777778, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI302344767, Length=327, Percent_Identity=56.2691131498471, Blast_Score=358, Evalue=4e-99,
Organism=Homo sapiens, GI302344762, Length=395, Percent_Identity=48.6075949367089, Blast_Score=338, Evalue=6e-93,
Organism=Homo sapiens, GI55956775, Length=356, Percent_Identity=45.2247191011236, Blast_Score=277, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI17537653, Length=396, Percent_Identity=45.7070707070707, Blast_Score=327, Evalue=7e-90,
Organism=Drosophila melanogaster, GI24585051, Length=391, Percent_Identity=56.2659846547315, Blast_Score=438, Evalue=1e-123,
Organism=Drosophila melanogaster, GI19921506, Length=391, Percent_Identity=55.2429667519182, Blast_Score=432, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 41509; Mature: 41378

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANRVCIAGVGMIAFAKPGASEPYHLMAARAGRQALADAGIGYDALQQAYVGYVYGDSTS
CCCCEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCC
GQKAVYELGMTGIPVINVNNNCSTGSTALFLARQAVESGAADCVLALGFEQMKPGALGTV
CCHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCCCC
FDDRPSPFEDFDREAEALVGMPELPLALRYFGGAGLGHMQKYGTPLEAFARIRAKASRHA
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
ARNPLALLRKELSTEDVMNAPMLWPGVMTRLMACPPTCGAAAAVLVSEAYARKNGLRTDV
CCCHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
AIRAQAMTTDRPDTFDSRDMMKVVGAGMSRAAAQSVYEQAGIGPEDLDVVELHDCFAHNE
EEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHCCC
LITYEALGLCPEGGAAAFIDAGDNTYGGRVVTNPSGGLLSKGHPLGATGLAQCYELTHQL
EEEEHHHCCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
RGTAEQRQVDGARVALQHNLGLGGACVVTLYEATA
HCCHHHHHCCCCEEEEEECCCCCCEEEEEEEECCC
>Mature Secondary Structure 
ANRVCIAGVGMIAFAKPGASEPYHLMAARAGRQALADAGIGYDALQQAYVGYVYGDSTS
CCCEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCC
GQKAVYELGMTGIPVINVNNNCSTGSTALFLARQAVESGAADCVLALGFEQMKPGALGTV
CCHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCCCC
FDDRPSPFEDFDREAEALVGMPELPLALRYFGGAGLGHMQKYGTPLEAFARIRAKASRHA
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
ARNPLALLRKELSTEDVMNAPMLWPGVMTRLMACPPTCGAAAAVLVSEAYARKNGLRTDV
CCCHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
AIRAQAMTTDRPDTFDSRDMMKVVGAGMSRAAAQSVYEQAGIGPEDLDVVELHDCFAHNE
EEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHCCC
LITYEALGLCPEGGAAAFIDAGDNTYGGRVVTNPSGGLLSKGHPLGATGLAQCYELTHQL
EEEEHHHCCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
RGTAEQRQVDGARVALQHNLGLGGACVVTLYEATA
HCCHHHHHCCCCEEEEEECCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]