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The map label for this gene is hsdS [H]

Identifier: 124265199

GI number: 124265199

Start: 7643

End: 8881

Strand: Direct

Name: hsdS [H]

Synonym: Mpe_A0006

Alternate gene names: 124265199

Gene position: 7643-8881 (Clockwise)

Preceding gene: 124265198

Following gene: 124265200

Centisome position: 0.19

GC content: 61.99

Gene sequence:

>1239_bases
ATGAAGAGCGATTGCTACGTGGATGCCGGGGTTCGTGTTGTCCGCGGCACCAACTTGACTGGCGGCCGATCGTTCTCGGG
TGAGTTTGTATTCATCACGCCAGAGAAGGCTGTAGAACTCAATTCGGCGAACCTGTCGCCGAATGACTTGGTCTTCCCTC
ATCGTGGCGCTATTGGCGAAGTTGGCATCGTCCCGGAAGACGGCGAGAGGTACGTTCTGTCCTCAAGCCTGATGAAGCTG
ACATGCGATGTGGCCCGTGCACACCCGGACTTCGTCTACTACTTTTTCAAGTCTGCGATTGGGCGCTTCGAACTTCTCAA
GAACTCATCGCAGGTCGGCACGCCGGGTATTGGCCAGCCACTGACATCACTCAAACAAATCAAGCTGAGGCTGCCGCCAG
TCGGCGAGCAGGTAGCGATTGCGGCCGCTCTGCGTGCTCTCGACGACCGCATCGCCCTCCTGCGCGACACCAACGCCACC
CTCGAAGCGATCGCGCAGGCGCTGTTCAAGTCGTGGTTCGTCGACTTCGATCCCGTTCGCGCCAAGAGCCAAGGCCTCGC
CCCGGCCGGCATGGACGAAGCCACGGCGGCCCTGTTTCCAGAGGGGGTCGAGGAGTCTGCTTTGGGGCCAGTGCCCAGGG
GGTGGCGCGCTGCAACGTTGGCAGAAACCTTCGAGATCAATCCCTCGCGCAGCCTTCCGAAGGATTCAGAGGCGAAGTAC
CTCGAGATGGCCGGTGTGCCGACCACGGGCCATTGCGCCGAGTCGATCGCGGTGCGTGCCTTCGGGTCCGGCACCAAGTT
TCGGAACGGCGACACGCTGCTGGCGCGCATCACGCCCTGCCTCGAAAACGGCAAGACGGCGTTCGTCGATTTCCTCGTGG
AAGATGAGATCGGCTGGGGATCGACAGAGTTCATCGTGCTGCGGCCTAAGGCGCCGCTGCCCGATTACTTCGCCTATCTG
CTGTGCAGACACGCACCGTTTCGCGAGTTTGCCGAGCGCAGCATGTCAGGGACGAGTGGACGTCAGCGGGTGCAGAACGA
TGTGCTCGCGACCTATCGGATTGCCGTGCCGCCATCAGCAGTTGCAGAAGCTTTCGGCGCGCTGATCAATCCACTGCGGC
ACGCGATCACGAGCAACCATGCGAGGGGAGCAACCCTTGGCGCGCTGCGTGATGCGCTGTTGCCTCGTCTGATCTCCGGC
CAACTCCGCCTGCCTGACGCTGTGGCGCTGGCCGCCTGA

Upstream 100 bases:

>100_bases
GGTGGGCTCGGGTATGAGTTCTGAATGGCCCTTGATCTCGATCGAAGAGATCAAGGCCCCCGGAGCGGGAAGCATTGCAA
TCGGCCCATTCGGCTCGCGG

Downstream 100 bases:

>100_bases
GCTCTTGCCGCCATCGGGCACACTTCCGGCACTTCAGAAAGCTGCTCCCACCATGGCCACCTTGTCCACCGTGCCACGCA
TCCACTACCTGCGGGTGCAG

Product: restriction modification system, type I

Products: NA

Alternate protein names: S.StySJI; Type I restriction enzyme StySJI specificity protein; S protein [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKSDCYVDAGVRVVRGTNLTGGRSFSGEFVFITPEKAVELNSANLSPNDLVFPHRGAIGEVGIVPEDGERYVLSSSLMKL
TCDVARAHPDFVYYFFKSAIGRFELLKNSSQVGTPGIGQPLTSLKQIKLRLPPVGEQVAIAAALRALDDRIALLRDTNAT
LEAIAQALFKSWFVDFDPVRAKSQGLAPAGMDEATAALFPEGVEESALGPVPRGWRAATLAETFEINPSRSLPKDSEAKY
LEMAGVPTTGHCAESIAVRAFGSGTKFRNGDTLLARITPCLENGKTAFVDFLVEDEIGWGSTEFIVLRPKAPLPDYFAYL
LCRHAPFREFAERSMSGTSGRQRVQNDVLATYRIAVPPSAVAEAFGALINPLRHAITSNHARGATLGALRDALLPRLISG
QLRLPDAVALAA

Sequences:

>Translated_412_residues
MKSDCYVDAGVRVVRGTNLTGGRSFSGEFVFITPEKAVELNSANLSPNDLVFPHRGAIGEVGIVPEDGERYVLSSSLMKL
TCDVARAHPDFVYYFFKSAIGRFELLKNSSQVGTPGIGQPLTSLKQIKLRLPPVGEQVAIAAALRALDDRIALLRDTNAT
LEAIAQALFKSWFVDFDPVRAKSQGLAPAGMDEATAALFPEGVEESALGPVPRGWRAATLAETFEINPSRSLPKDSEAKY
LEMAGVPTTGHCAESIAVRAFGSGTKFRNGDTLLARITPCLENGKTAFVDFLVEDEIGWGSTEFIVLRPKAPLPDYFAYL
LCRHAPFREFAERSMSGTSGRQRVQNDVLATYRIAVPPSAVAEAFGALINPLRHAITSNHARGATLGALRDALLPRLISG
QLRLPDAVALAA
>Mature_412_residues
MKSDCYVDAGVRVVRGTNLTGGRSFSGEFVFITPEKAVELNSANLSPNDLVFPHRGAIGEVGIVPEDGERYVLSSSLMKL
TCDVARAHPDFVYYFFKSAIGRFELLKNSSQVGTPGIGQPLTSLKQIKLRLPPVGEQVAIAAALRALDDRIALLRDTNAT
LEAIAQALFKSWFVDFDPVRAKSQGLAPAGMDEATAALFPEGVEESALGPVPRGWRAATLAETFEINPSRSLPKDSEAKY
LEMAGVPTTGHCAESIAVRAFGSGTKFRNGDTLLARITPCLENGKTAFVDFLVEDEIGWGSTEFIVLRPKAPLPDYFAYL
LCRHAPFREFAERSMSGTSGRQRVQNDVLATYRIAVPPSAVAEAFGALINPLRHAITSNHARGATLGALRDALLPRLISG
QLRLPDAVALAA

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 44385; Mature: 44385

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSDCYVDAGVRVVRGTNLTGGRSFSGEFVFITPEKAVELNSANLSPNDLVFPHRGAIGE
CCCCEEECCCEEEEECCCCCCCCCCCCCEEEECCHHHEEECCCCCCCCCEECCCCCCCCC
VGIVPEDGERYVLSSSLMKLTCDVARAHPDFVYYFFKSAIGRFELLKNSSQVGTPGIGQP
CCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
LTSLKQIKLRLPPVGEQVAIAAALRALDDRIALLRDTNATLEAIAQALFKSWFVDFDPVR
HHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
AKSQGLAPAGMDEATAALFPEGVEESALGPVPRGWRAATLAETFEINPSRSLPKDSEAKY
HHCCCCCCCCCCHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHEECCCCCCCCCCCCCCE
LEMAGVPTTGHCAESIAVRAFGSGTKFRNGDTLLARITPCLENGKTAFVDFLVEDEIGWG
EEECCCCCCCHHHHHHEEEEECCCCCCCCCCEEEEEEHHHHHCCCEEEEEEEEECCCCCC
STEFIVLRPKAPLPDYFAYLLCRHAPFREFAERSMSGTSGRQRVQNDVLATYRIAVPPSA
CEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHEEEEEEECCHHH
VAEAFGALINPLRHAITSNHARGATLGALRDALLPRLISGQLRLPDAVALAA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCC
>Mature Secondary Structure
MKSDCYVDAGVRVVRGTNLTGGRSFSGEFVFITPEKAVELNSANLSPNDLVFPHRGAIGE
CCCCEEECCCEEEEECCCCCCCCCCCCCEEEECCHHHEEECCCCCCCCCEECCCCCCCCC
VGIVPEDGERYVLSSSLMKLTCDVARAHPDFVYYFFKSAIGRFELLKNSSQVGTPGIGQP
CCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
LTSLKQIKLRLPPVGEQVAIAAALRALDDRIALLRDTNATLEAIAQALFKSWFVDFDPVR
HHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCC
AKSQGLAPAGMDEATAALFPEGVEESALGPVPRGWRAATLAETFEINPSRSLPKDSEAKY
HHCCCCCCCCCCHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHEECCCCCCCCCCCCCCE
LEMAGVPTTGHCAESIAVRAFGSGTKFRNGDTLLARITPCLENGKTAFVDFLVEDEIGWG
EEECCCCCCCHHHHHHEEEEECCCCCCCCCCEEEEEEHHHHHCCCEEEEEEEEECCCCCC
STEFIVLRPKAPLPDYFAYLLCRHAPFREFAERSMSGTSGRQRVQNDVLATYRIAVPPSA
CEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHEEEEEEECCHHH
VAEAFGALINPLRHAITSNHARGATLGALRDALLPRLISGQLRLPDAVALAA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2838725; 11677609; 3025838 [H]