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The map label for this gene is hsdM [C]

Identifier: 124265198

GI number: 124265198

Start: 5980

End: 7566

Strand: Direct

Name: hsdM [C]

Synonym: Mpe_A0005

Alternate gene names: 124265198

Gene position: 5980-7566 (Clockwise)

Preceding gene: 124265197

Following gene: 124265199

Centisome position: 0.15

GC content: 67.36

Gene sequence:

>1587_bases
ATGCCGGACGACCTGAAGAGGACCCTCTGGGCCACCGCCGACAAGCTGCGCGCCAACATGGACGCGGCCGAGTACAAGCA
CCTGGTGCTGGGCCTGATCTTCCTGAAGTACATCTCCGACACCTTCCAGGCCCGCCGCACCGAACTGACGGCGCGCTTCG
CCGACCCGGCCGACGAATACCACCTCGACGGCGCCACGCCGGCCGACATCGCCGCCGAACTGGAAGACCGCGACTACTAC
CGCGAGGCCAACGTCTTCTGGGTACCGGAAGCGGCCCGCTGGGAAGCCATCCGTTCTGCGGCCAAGCAGCCCGACATCGG
CAAGCGCATCGACGATGCCCTGAGCCTCATCGAAGCCGAGAACCCCAAGCTCAAGGGCATCCTCGACAAGCGCTTCGCGC
GCGCGCAGCTGCCCGACGGCAAGCTGGGCGAACTGGTGGACCTGGTCTCCACCATCGGCTTCGGCGAGAGCGCCGCCACT
GCGCGCGACGTGCTGGGCCAGGTGTACGAATACTTCCTCGGCATGTTCGCCAGCGCCGAAGGCAAGCGCGGCGGTCAGTT
CTACACGCCGCGCAGCATCGTCAAGACACTGGTCGCCGTGCTGGCGCCGCACCACGGCAAGGTGTACGACCCGTGCTGCG
GCAGCGGCGGCATGTTCGTGCAGAGCGAAGAGTTCATCCTCAGCCACGGCGGCAAGCTGGGCGACGTGGCCATCTTCGGC
CAGGAGGCCAACCCCACCACTTGGCGGCTCGCGGCAATGAACCTCGCGATCCGCGGCATCGACTTCAACCTCGGCCGCGA
GCCGGCCGACACCTTCACCAAGAACCAGTTTCCCGACCTGCGCGCCGACTTCATCCTGGCCAACCCGCCGTTCAACATCA
GCGACTGGTGGCACGCGAGCCTGACGGGTGACGCTCGTTGGCACTACGGCGACCCGCCGCAAGGCAATGCCAACTACGCC
TGGCTGCAGCACATGCTGCACCACCTGAAGCCCGGCGGCCGCGCCGGCATCGTGCTGGCCAACGGCAGCATGAGCAGCAG
CCAGAACAACGAAGGCCAGATCCGCGCCGCGACGGTGGAGGCCGACGTGGTGGAGGTGATGATCGCGCTGCCGGGCCAGC
TGTTCTTCAACACGCAGATCCCGGCGTGCCTGTGGTTCCTGGTGAAGGACAAGCGGCAGCGCCGAGGCGAGGTGCTGTTC
ATCGACGCGCGCAAGCTGGCCACGATGATCAGCCGCGTGCAGTGCGAGCTGAAGGACGAGGTGATCGAGCGGATCGCCGG
GACCGTGGCCGCGTGGCGCGCATCACCCCCTCTCCCGCTGGCGGGAGGGGGTCGGGGTGAGGGTGCTTCGAGCTACGCCG
ACATCCCCGGCTACTGCCGCAGCGTGAAGCTCGCCGAGATCGCCGAGCACGGGCATGTGCTGACGCCGGGGCGCTATGTG
GGCGCGGAAGCGGTGGACGATGATGGCGAGAGCTTCGAGGCCAAGATGCAGGCGCTGACCGAGAAGCTCGGGGAGCAGAT
GGCGAAGGGGGCGGAGCTGGATGCGGTGATTCGGCAGAAGCTGGGTGGGCTCGGGTATGAGTTCTGA

Upstream 100 bases:

>100_bases
CGGAGCTGCTGGAGTGGCCGGCGCTCGCGCCCTAGGGACAACGGCTCAGCCGCGGGCCGCGACAATCGGCCGCACCTTCC
CACGCGACGCCCTACTTCCC

Downstream 100 bases:

>100_bases
ATGGCCCTTGATCTCGATCGAAGAGATCAAGGCCCCCGGAGCGGGAAGCATTGCAATCGGCCCATTCGGCTCGCGGATGA
AGAGCGATTGCTACGTGGAT

Product: type I restriction-modification system, M subunit

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MPDDLKRTLWATADKLRANMDAAEYKHLVLGLIFLKYISDTFQARRTELTARFADPADEYHLDGATPADIAAELEDRDYY
REANVFWVPEAARWEAIRSAAKQPDIGKRIDDALSLIEAENPKLKGILDKRFARAQLPDGKLGELVDLVSTIGFGESAAT
ARDVLGQVYEYFLGMFASAEGKRGGQFYTPRSIVKTLVAVLAPHHGKVYDPCCGSGGMFVQSEEFILSHGGKLGDVAIFG
QEANPTTWRLAAMNLAIRGIDFNLGREPADTFTKNQFPDLRADFILANPPFNISDWWHASLTGDARWHYGDPPQGNANYA
WLQHMLHHLKPGGRAGIVLANGSMSSSQNNEGQIRAATVEADVVEVMIALPGQLFFNTQIPACLWFLVKDKRQRRGEVLF
IDARKLATMISRVQCELKDEVIERIAGTVAAWRASPPLPLAGGGRGEGASSYADIPGYCRSVKLAEIAEHGHVLTPGRYV
GAEAVDDDGESFEAKMQALTEKLGEQMAKGAELDAVIRQKLGGLGYEF

Sequences:

>Translated_528_residues
MPDDLKRTLWATADKLRANMDAAEYKHLVLGLIFLKYISDTFQARRTELTARFADPADEYHLDGATPADIAAELEDRDYY
REANVFWVPEAARWEAIRSAAKQPDIGKRIDDALSLIEAENPKLKGILDKRFARAQLPDGKLGELVDLVSTIGFGESAAT
ARDVLGQVYEYFLGMFASAEGKRGGQFYTPRSIVKTLVAVLAPHHGKVYDPCCGSGGMFVQSEEFILSHGGKLGDVAIFG
QEANPTTWRLAAMNLAIRGIDFNLGREPADTFTKNQFPDLRADFILANPPFNISDWWHASLTGDARWHYGDPPQGNANYA
WLQHMLHHLKPGGRAGIVLANGSMSSSQNNEGQIRAATVEADVVEVMIALPGQLFFNTQIPACLWFLVKDKRQRRGEVLF
IDARKLATMISRVQCELKDEVIERIAGTVAAWRASPPLPLAGGGRGEGASSYADIPGYCRSVKLAEIAEHGHVLTPGRYV
GAEAVDDDGESFEAKMQALTEKLGEQMAKGAELDAVIRQKLGGLGYEF
>Mature_527_residues
PDDLKRTLWATADKLRANMDAAEYKHLVLGLIFLKYISDTFQARRTELTARFADPADEYHLDGATPADIAAELEDRDYYR
EANVFWVPEAARWEAIRSAAKQPDIGKRIDDALSLIEAENPKLKGILDKRFARAQLPDGKLGELVDLVSTIGFGESAATA
RDVLGQVYEYFLGMFASAEGKRGGQFYTPRSIVKTLVAVLAPHHGKVYDPCCGSGGMFVQSEEFILSHGGKLGDVAIFGQ
EANPTTWRLAAMNLAIRGIDFNLGREPADTFTKNQFPDLRADFILANPPFNISDWWHASLTGDARWHYGDPPQGNANYAW
LQHMLHHLKPGGRAGIVLANGSMSSSQNNEGQIRAATVEADVVEVMIALPGQLFFNTQIPACLWFLVKDKRQRRGEVLFI
DARKLATMISRVQCELKDEVIERIAGTVAAWRASPPLPLAGGGRGEGASSYADIPGYCRSVKLAEIAEHGHVLTPGRYVG
AEAVDDDGESFEAKMQALTEKLGEQMAKGAELDAVIRQKLGGLGYEF

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=319, Percent_Identity=23.1974921630094, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 57998; Mature: 57867

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDDLKRTLWATADKLRANMDAAEYKHLVLGLIFLKYISDTFQARRTELTARFADPADEY
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHC
HLDGATPADIAAELEDRDYYREANVFWVPEAARWEAIRSAAKQPDIGKRIDDALSLIEAE
CCCCCCHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
NPKLKGILDKRFARAQLPDGKLGELVDLVSTIGFGESAATARDVLGQVYEYFLGMFASAE
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GKRGGQFYTPRSIVKTLVAVLAPHHGKVYDPCCGSGGMFVQSEEFILSHGGKLGDVAIFG
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHCCCCCCCEEEEC
QEANPTTWRLAAMNLAIRGIDFNLGREPADTFTKNQFPDLRADFILANPPFNISDWWHAS
CCCCCCEEEEEEEEEEEEEEECCCCCCCHHHHCCCCCCCCCCCEEEECCCCCCCCCEEEE
LTGDARWHYGDPPQGNANYAWLQHMLHHLKPGGRAGIVLANGSMSSSQNNEGQIRAATVE
ECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEH
ADVVEVMIALPGQLFFNTQIPACLWFLVKDKRQRRGEVLFIDARKLATMISRVQCELKDE
HHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHH
VIERIAGTVAAWRASPPLPLAGGGRGEGASSYADIPGYCRSVKLAEIAEHGHVLTPGRYV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCC
GAEAVDDDGESFEAKMQALTEKLGEQMAKGAELDAVIRQKLGGLGYEF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PDDLKRTLWATADKLRANMDAAEYKHLVLGLIFLKYISDTFQARRTELTARFADPADEY
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHC
HLDGATPADIAAELEDRDYYREANVFWVPEAARWEAIRSAAKQPDIGKRIDDALSLIEAE
CCCCCCHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
NPKLKGILDKRFARAQLPDGKLGELVDLVSTIGFGESAATARDVLGQVYEYFLGMFASAE
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GKRGGQFYTPRSIVKTLVAVLAPHHGKVYDPCCGSGGMFVQSEEFILSHGGKLGDVAIFG
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHCCCCCCCEEEEC
QEANPTTWRLAAMNLAIRGIDFNLGREPADTFTKNQFPDLRADFILANPPFNISDWWHAS
CCCCCCEEEEEEEEEEEEEEECCCCCCCHHHHCCCCCCCCCCCEEEECCCCCCCCCEEEE
LTGDARWHYGDPPQGNANYAWLQHMLHHLKPGGRAGIVLANGSMSSSQNNEGQIRAATVE
ECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEH
ADVVEVMIALPGQLFFNTQIPACLWFLVKDKRQRRGEVLFIDARKLATMISRVQCELKDE
HHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHH
VIERIAGTVAAWRASPPLPLAGGGRGEGASSYADIPGYCRSVKLAEIAEHGHVLTPGRYV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCC
GAEAVDDDGESFEAKMQALTEKLGEQMAKGAELDAVIRQKLGGLGYEF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]