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The map label for this gene is lhr [C]

Identifier: 124027814

GI number: 124027814

Start: 948448

End: 951117

Strand: Reverse

Name: lhr [C]

Synonym: Hbut_0941

Alternate gene names: 124027814

Gene position: 951117-948448 (Counterclockwise)

Preceding gene: 124027819

Following gene: 124027813

Centisome position: 57.05

GC content: 52.51

Gene sequence:

>2670_bases
TTGGCGATAGTGTATGCTGGCCACTGCCCGGGCGACGAGGGCGTATATGAACTGCTTAGGCCATATGTGGCAGAATGGTT
TAAGAGGAGGTATGGAAGCTTCACGCCTCCCCAGCGTTGCGCAATACCGCTGATTAAGAAGGGGTATAATGTTCTCGTCT
CGTCGCCCACGGGGACTGGCAAGACTCTAGCAGTGTTCCTAGGTATTATTGACGAGCTGTTCCGGCTGGGGGAGGCTGGC
GAGCTTGAGGAACAGATCTATGCTATCTACGTGTCACCCCTTCGAGCGTTAAACAATGACATGAAACGTAACTTGCTCGA
CCCCCTTGAGGGTATAAGGCGTGTAGCAGAGGGTATGGGCCATAGTCTTCCCGAGATACGGGTTGCTGTGAGAACGAGTG
ATACTCCTCCGAGCGAGAAACAACGCATGACAAGGCAGCCACCACACATATTGATAACAACGCCGGAGAGCCTAGCGATA
GCACTTAATGCGCCGAGGTTCCGAGAAAGACTCGCTACCACGAGATGGGTGGTAGTAGATGAAATACATGAACTTGCATC
GAGTAAGCGCGGCTCACATCTAAGCCTCTCGCTTGAGAGGCTTGAGAACCTTGTTGGCAGGCCTATACAGAGAATAGGAT
TATCGGCAACAATTGCGCCACTGGAAGAGGTTGCAAAGTTCCTCGTAGGTTTCCGCGACACCGGCGAGCCTAGGGACTGC
ATTATAGTCGATGCCAGGTTCGCTAAGCCGATAGACATCCGCGTTCTATGCCCTGTTAGTGACCTTATACATACACCTGC
TGAGCAAGTGAACGAGGCTATCTATAGACTACTTGCAAAACTAATACGAGAGCACCGCACAACGCTCGTATTCACGAATA
CGCGGAGTGCGACAGAGAAAGTCGTCTATAAGCTGAAGAAGTTATTGAAGGAGGAGGGTATAGCAGACTTCGACGAGATA
GAGGCACATCATAGCAGTCTTAGCCGTGATCTAAGGCTTGCTGTCGAGGAGAAACTGAAGAGGGGAGAGCTAAAGGTAGT
GGTATCATCTACCAGTTTGGAGCTGGGCATAGACATAGGCTACATAGACCTGGTAGTCCTTCTGAGCAGCCCCAAGAGCG
TTTCAAGGCTCCTGCAGAGAGTTGGCCGTGCCGGTCACCACATTAGACAGGTTAGCAAGGGGAGGATCATAGTTGTCGAC
CGCGACGACCTGGTAGAATGCACCGTGCTGGCCAAGGCCGCGCTTGAGAGGAAGATAGACAGGGTACACATACCCAGGAA
CCCGCTAGACGTTCTGGCACAACATCTTGTAGGCATGGCCCTTGAGAGGAAGTGGCGTATTGAGGAGGCCTACCGGCTCG
TGAGGCGAAGCTATAGCTTCCACACACTATCCCTCGAGGACTTTGTGAACGTGCTACGCTTTCTAGCTGGGCGCTATGGC
CTCGAGGAGTATCGGGTCTACGCAAAGATATGGCTTGACGAGAAGGAGGGAGTGTTCGGCCGTAAGCGTGGTGCACGGAT
GATATACTACCTCAACAGCGGCACCATACCCGACGAGGTTAAGGTAAAGGTGTTTACTCTTGACGGACGCTATGTGGGCG
ACCTGGAAGAACCCTTCGTCCAGATACTAACGCCAGGCGACATCTTCGTCCTTGGTGGCAAGACATACGAGTTCATACGC
TCGGAGGGCATGCGGATCTACGTTAGACCCGCCGAGGGACAAAAACCCACCGTACCAAGCTGGTTCTCCGAGATGCTACC
ACTAGCCTTTGACTCCGCGCTACTAGTCGGTGCTTTCCGCCGCTGGATAACCGAGATGATAGAGGAGGGAGTACCACGAG
AGGAGGCTGTGAGGCTAATTGCTAAGCACTACAACCTTGAGCATCATGCAGCCGAGAATATCTACGACTATGTGCTCGAG
CAATACCTCTTCACAGGAGGCAAGGTCCCAAGCGACAAGATGATACTTGTCGAGCTATTCCACGACCTAGAATCAGACGC
TACGTCAATAATCTTCCATAGCCTCTTCGGTCGCAGAGTAAATGATGCACTATCCAGGGCCTACGCCTACCAGCTAACAA
GAATAGCAGGAACTAATGTGCGCGTCACCGTGACCGATAACGCTTTCATGCTCACAGTGCCAGGGCTGAGAGACGACATA
AACCTTGAAGAGCTAGTCTACAGCGTTAAGCCCAATGAGCTAGAAGATATTCTCAAGAGAGTGCTACGCAACACCGAGCT
GTTGAAGAGAAGGTTTAGATATTGCGCCGAGAGAAGCTTCATGCTGCTGAGAAGGTACCGTGGTAGAGAGAAGGACCCTC
ACACGCTCCAGCTCAACGCCCAGACGTTGCTAGAAGCTGTGGAGCGCATACCGGGCTTCCCCGTGCTTAAGGAGGCTTAT
CGCGAGATACTCGAGGACTACATGGACATAGTTAATGCCCGGCTTGTCTTAGAGTGGCTCCACGAGGGCCATGTAATGGT
GGACTACTTCGGCCCTACGACAGTACCGAGCCCCTTCGCCCACCACATAGTGGTTAGGGGCTATAGCGACATAGTACTCA
TGGAGGATAGGAAGAAACTGCTAATGGAGCTACACGAGAGAGTGATGGAGCTGCTAAGAAGGCGTATGTACCGCGGAGAG
CCTAGAGAGGCTGTAGAAGCCGGCAGATAG

Upstream 100 bases:

>100_bases
CCCTAAGGGGGCGACGTGTTTCTAAATTAAGCCCTCGGGGCCCGGTGGAGAAGGGTAAGGTGTATGGCGTAGTGGCGCTG
ATGTAGGGTGGTGCTAGCCC

Downstream 100 bases:

>100_bases
CCCCGGGAAATAGGGAAATAGGAGGATAATTGAGGGCTCGGCGAAGGACCACCTCGTCACCCCGTCAGACTCGATCCCGG
GGTATCTCCTCAACGCCCGT

Product: ATP-dependent helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 889; Mature: 888

Protein sequence:

>889_residues
MAIVYAGHCPGDEGVYELLRPYVAEWFKRRYGSFTPPQRCAIPLIKKGYNVLVSSPTGTGKTLAVFLGIIDELFRLGEAG
ELEEQIYAIYVSPLRALNNDMKRNLLDPLEGIRRVAEGMGHSLPEIRVAVRTSDTPPSEKQRMTRQPPHILITTPESLAI
ALNAPRFRERLATTRWVVVDEIHELASSKRGSHLSLSLERLENLVGRPIQRIGLSATIAPLEEVAKFLVGFRDTGEPRDC
IIVDARFAKPIDIRVLCPVSDLIHTPAEQVNEAIYRLLAKLIREHRTTLVFTNTRSATEKVVYKLKKLLKEEGIADFDEI
EAHHSSLSRDLRLAVEEKLKRGELKVVVSSTSLELGIDIGYIDLVVLLSSPKSVSRLLQRVGRAGHHIRQVSKGRIIVVD
RDDLVECTVLAKAALERKIDRVHIPRNPLDVLAQHLVGMALERKWRIEEAYRLVRRSYSFHTLSLEDFVNVLRFLAGRYG
LEEYRVYAKIWLDEKEGVFGRKRGARMIYYLNSGTIPDEVKVKVFTLDGRYVGDLEEPFVQILTPGDIFVLGGKTYEFIR
SEGMRIYVRPAEGQKPTVPSWFSEMLPLAFDSALLVGAFRRWITEMIEEGVPREEAVRLIAKHYNLEHHAAENIYDYVLE
QYLFTGGKVPSDKMILVELFHDLESDATSIIFHSLFGRRVNDALSRAYAYQLTRIAGTNVRVTVTDNAFMLTVPGLRDDI
NLEELVYSVKPNELEDILKRVLRNTELLKRRFRYCAERSFMLLRRYRGREKDPHTLQLNAQTLLEAVERIPGFPVLKEAY
REILEDYMDIVNARLVLEWLHEGHVMVDYFGPTTVPSPFAHHIVVRGYSDIVLMEDRKKLLMELHERVMELLRRRMYRGE
PREAVEAGR

Sequences:

>Translated_889_residues
MAIVYAGHCPGDEGVYELLRPYVAEWFKRRYGSFTPPQRCAIPLIKKGYNVLVSSPTGTGKTLAVFLGIIDELFRLGEAG
ELEEQIYAIYVSPLRALNNDMKRNLLDPLEGIRRVAEGMGHSLPEIRVAVRTSDTPPSEKQRMTRQPPHILITTPESLAI
ALNAPRFRERLATTRWVVVDEIHELASSKRGSHLSLSLERLENLVGRPIQRIGLSATIAPLEEVAKFLVGFRDTGEPRDC
IIVDARFAKPIDIRVLCPVSDLIHTPAEQVNEAIYRLLAKLIREHRTTLVFTNTRSATEKVVYKLKKLLKEEGIADFDEI
EAHHSSLSRDLRLAVEEKLKRGELKVVVSSTSLELGIDIGYIDLVVLLSSPKSVSRLLQRVGRAGHHIRQVSKGRIIVVD
RDDLVECTVLAKAALERKIDRVHIPRNPLDVLAQHLVGMALERKWRIEEAYRLVRRSYSFHTLSLEDFVNVLRFLAGRYG
LEEYRVYAKIWLDEKEGVFGRKRGARMIYYLNSGTIPDEVKVKVFTLDGRYVGDLEEPFVQILTPGDIFVLGGKTYEFIR
SEGMRIYVRPAEGQKPTVPSWFSEMLPLAFDSALLVGAFRRWITEMIEEGVPREEAVRLIAKHYNLEHHAAENIYDYVLE
QYLFTGGKVPSDKMILVELFHDLESDATSIIFHSLFGRRVNDALSRAYAYQLTRIAGTNVRVTVTDNAFMLTVPGLRDDI
NLEELVYSVKPNELEDILKRVLRNTELLKRRFRYCAERSFMLLRRYRGREKDPHTLQLNAQTLLEAVERIPGFPVLKEAY
REILEDYMDIVNARLVLEWLHEGHVMVDYFGPTTVPSPFAHHIVVRGYSDIVLMEDRKKLLMELHERVMELLRRRMYRGE
PREAVEAGR
>Mature_888_residues
AIVYAGHCPGDEGVYELLRPYVAEWFKRRYGSFTPPQRCAIPLIKKGYNVLVSSPTGTGKTLAVFLGIIDELFRLGEAGE
LEEQIYAIYVSPLRALNNDMKRNLLDPLEGIRRVAEGMGHSLPEIRVAVRTSDTPPSEKQRMTRQPPHILITTPESLAIA
LNAPRFRERLATTRWVVVDEIHELASSKRGSHLSLSLERLENLVGRPIQRIGLSATIAPLEEVAKFLVGFRDTGEPRDCI
IVDARFAKPIDIRVLCPVSDLIHTPAEQVNEAIYRLLAKLIREHRTTLVFTNTRSATEKVVYKLKKLLKEEGIADFDEIE
AHHSSLSRDLRLAVEEKLKRGELKVVVSSTSLELGIDIGYIDLVVLLSSPKSVSRLLQRVGRAGHHIRQVSKGRIIVVDR
DDLVECTVLAKAALERKIDRVHIPRNPLDVLAQHLVGMALERKWRIEEAYRLVRRSYSFHTLSLEDFVNVLRFLAGRYGL
EEYRVYAKIWLDEKEGVFGRKRGARMIYYLNSGTIPDEVKVKVFTLDGRYVGDLEEPFVQILTPGDIFVLGGKTYEFIRS
EGMRIYVRPAEGQKPTVPSWFSEMLPLAFDSALLVGAFRRWITEMIEEGVPREEAVRLIAKHYNLEHHAAENIYDYVLEQ
YLFTGGKVPSDKMILVELFHDLESDATSIIFHSLFGRRVNDALSRAYAYQLTRIAGTNVRVTVTDNAFMLTVPGLRDDIN
LEELVYSVKPNELEDILKRVLRNTELLKRRFRYCAERSFMLLRRYRGREKDPHTLQLNAQTLLEAVERIPGFPVLKEAYR
EILEDYMDIVNARLVLEWLHEGHVMVDYFGPTTVPSPFAHHIVVRGYSDIVLMEDRKKLLMELHERVMELLRRRMYRGEP
REAVEAGR

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=944, Percent_Identity=31.4618644067797, Blast_Score=405, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17537519, Length=400, Percent_Identity=24.25, Blast_Score=66, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320497, Length=389, Percent_Identity=27.2493573264781, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI9755332, Length=472, Percent_Identity=25.4237288135593, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 101902; Mature: 101770

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVYAGHCPGDEGVYELLRPYVAEWFKRRYGSFTPPQRCAIPLIKKGYNVLVSSPTGTG
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHCCCEEEEECCCCCC
KTLAVFLGIIDELFRLGEAGELEEQIYAIYVSPLRALNNDMKRNLLDPLEGIRRVAEGMG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HSLPEIRVAVRTSDTPPSEKQRMTRQPPHILITTPESLAIALNAPRFRERLATTRWVVVD
CCCCCEEEEEECCCCCCHHHHHHCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
EIHELASSKRGSHLSLSLERLENLVGRPIQRIGLSATIAPLEEVAKFLVGFRDTGEPRDC
HHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCE
IIVDARFAKPIDIRVLCPVSDLIHTPAEQVNEAIYRLLAKLIREHRTTLVFTNTRSATEK
EEEECCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHH
VVYKLKKLLKEEGIADFDEIEAHHSSLSRDLRLAVEEKLKRGELKVVVSSTSLELGIDIG
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEEEH
YIDLVVLLSSPKSVSRLLQRVGRAGHHIRQVSKGRIIVVDRDDLVECTVLAKAALERKID
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHH
RVHIPRNPLDVLAQHLVGMALERKWRIEEAYRLVRRSYSFHTLSLEDFVNVLRFLAGRYG
HEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCC
LEEYRVYAKIWLDEKEGVFGRKRGARMIYYLNSGTIPDEVKVKVFTLDGRYVGDLEEPFV
HHHHEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCCEECCHHHHHH
QILTPGDIFVLGGKTYEFIRSEGMRIYVRPAEGQKPTVPSWFSEMLPLAFDSALLVGAFR
HEECCCCEEEECCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RWITEMIEEGVPREEAVRLIAKHYNLEHHAAENIYDYVLEQYLFTGGKVPSDKMILVELF
HHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
HDLESDATSIIFHSLFGRRVNDALSRAYAYQLTRIAGTNVRVTVTDNAFMLTVPGLRDDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEECCCCCCC
NLEELVYSVKPNELEDILKRVLRNTELLKRRFRYCAERSFMLLRRYRGREKDPHTLQLNA
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECH
QTLLEAVERIPGFPVLKEAYREILEDYMDIVNARLVLEWLHEGHVMVDYFGPTTVPSPFA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHH
HHIVVRGYSDIVLMEDRKKLLMELHERVMELLRRRMYRGEPREAVEAGR
HHEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure 
AIVYAGHCPGDEGVYELLRPYVAEWFKRRYGSFTPPQRCAIPLIKKGYNVLVSSPTGTG
EEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHCCCEEEEECCCCCC
KTLAVFLGIIDELFRLGEAGELEEQIYAIYVSPLRALNNDMKRNLLDPLEGIRRVAEGMG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HSLPEIRVAVRTSDTPPSEKQRMTRQPPHILITTPESLAIALNAPRFRERLATTRWVVVD
CCCCCEEEEEECCCCCCHHHHHHCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
EIHELASSKRGSHLSLSLERLENLVGRPIQRIGLSATIAPLEEVAKFLVGFRDTGEPRDC
HHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCE
IIVDARFAKPIDIRVLCPVSDLIHTPAEQVNEAIYRLLAKLIREHRTTLVFTNTRSATEK
EEEECCCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHH
VVYKLKKLLKEEGIADFDEIEAHHSSLSRDLRLAVEEKLKRGELKVVVSSTSLELGIDIG
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEEEH
YIDLVVLLSSPKSVSRLLQRVGRAGHHIRQVSKGRIIVVDRDDLVECTVLAKAALERKID
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHH
RVHIPRNPLDVLAQHLVGMALERKWRIEEAYRLVRRSYSFHTLSLEDFVNVLRFLAGRYG
HEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCC
LEEYRVYAKIWLDEKEGVFGRKRGARMIYYLNSGTIPDEVKVKVFTLDGRYVGDLEEPFV
HHHHEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCCEECCHHHHHH
QILTPGDIFVLGGKTYEFIRSEGMRIYVRPAEGQKPTVPSWFSEMLPLAFDSALLVGAFR
HEECCCCEEEECCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RWITEMIEEGVPREEAVRLIAKHYNLEHHAAENIYDYVLEQYLFTGGKVPSDKMILVELF
HHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
HDLESDATSIIFHSLFGRRVNDALSRAYAYQLTRIAGTNVRVTVTDNAFMLTVPGLRDDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEECCCCCCC
NLEELVYSVKPNELEDILKRVLRNTELLKRRFRYCAERSFMLLRRYRGREKDPHTLQLNA
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECH
QTLLEAVERIPGFPVLKEAYREILEDYMDIVNARLVLEWLHEGHVMVDYFGPTTVPSPFA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHH
HHIVVRGYSDIVLMEDRKKLLMELHERVMELLRRRMYRGEPREAVEAGR
HHEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726 [H]