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The map label for this gene is rsmB [H]

Identifier: 124027597

GI number: 124027597

Start: 706029

End: 707246

Strand: Reverse

Name: rsmB [H]

Synonym: Hbut_0718

Alternate gene names: 124027597

Gene position: 707246-706029 (Counterclockwise)

Preceding gene: 124027598

Following gene: 124027589

Centisome position: 42.42

GC content: 64.04

Gene sequence:

>1218_bases
ATGCCCCGTGTGCGGAACCCCGCTATCCAGGAGGAGGACATCCAGGAGGACATCCGGGCGCCGCCCCAGCTAGACTATGA
TGCTGGGCTGCTGCGGGAGCTGCGCAGGGTCTACGGCGGAGCCCTAAGCGCGGCGCTCCAGGCGATACTGGAGCCCCCCG
CCAGGTACTACGTCCGGGTAAACGTGCTCCGGGCTGACCCCGGCACGGTGCTCGACGAGATGAGGGCCCAGGGCCTGGAA
GTCTATGCTGACGAGGAGCTGCCGGAGGCCCTGTGGCTCCCGGTCCGGGGGCCCGTGGAGCCCCGGGACACCGGGTGCAG
GCTAGTGGTCGACAAGAGGGCCGCCGAGAGCATCATGCTGGGCGCGAACGTGTACGCCCCCGGCGTCGTAGCGCTGGACG
AGGCGTGCGCCAACCCCGGAGCAGAGGTCACAGTAGTCTCGGAGAACGGCGTACCCGTCGCCAACGCCGTGCTAGCCGAG
GACTACCGCCGTGCAATGGAGGAGGGGAGGGGCCTCGTAGCGGTCAACGTCCGGCCCCGCTACCGGGTGCCAAGCCTCCG
GGACACCGTGTGGTGGCGCCGGGGCGTCATCTACGAGCAAAGCCTCCCCTCCATGTACGCGTCCAGGATCCTAGACCCGG
AGCCCGGAGCAGTTATAGTGGACATGTGCGCAGCCCCCGGAGGCAAGACAAGCCACATCTACGAGCTAGTAAGGGGCGAG
GCAAGGATCATCGCCGTAGACCACTCCGCCAGGAAGACCGAGAGGATGAGAATGGAGCTAGGCCGGCTCGGCCACACCCG
CATAGAGGTCATACGGGCTGACTCCAGATACCTCGACCGCATCCTCGGCAGCGGGGTCGCCGACTACGTGCTCCTAGACC
CCCCATGCACAAGCCTAGGCGTAATCCCCAAGATCTACGACCGTAAGACACTCCGAGACGTCGCCAACACCGCGGAGTAC
CAGCGCCAGTTCCTCCGCGCAGCAGCCAAGCTGCTCAAGCCAGGCGGAGTACTAGTCTACTCAACATGCACCATGACACT
AATGGAGAACGAGGAAAACACACAATACGCCATAGAGAAGCTAGGCCTAAACCCGGAGGAACCACAATACCACAGGTTCA
GCAGAGGCCTAAACCAGGCATGGTACGCACAGCGCAGCCACCCACACGTACACCGCACAACAGGCTACTACATAGCACGC
CTACGCAAGAAACCATAA

Upstream 100 bases:

>100_bases
AGTACCGGAGCCTCCGCACACGGGGTATAAGCAGGGTGGAGGACTACGAGGCTGTCTGCCCAGCGTGCGGCTACCGGTCC
CGGAGGCCGGGTGAACGGGT

Downstream 100 bases:

>100_bases
CCCAACACCCCATGATGAACTGATGGGCCCCAGACCCCCACAGAAAGGGGGGCATGAAGAAATCCTTGGGCACTGAACCC
CCACAACACACCCACCACAG

Product: ribosomal RNA small subunit methyltransferase B

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MPRVRNPAIQEEDIQEDIRAPPQLDYDAGLLRELRRVYGGALSAALQAILEPPARYYVRVNVLRADPGTVLDEMRAQGLE
VYADEELPEALWLPVRGPVEPRDTGCRLVVDKRAAESIMLGANVYAPGVVALDEACANPGAEVTVVSENGVPVANAVLAE
DYRRAMEEGRGLVAVNVRPRYRVPSLRDTVWWRRGVIYEQSLPSMYASRILDPEPGAVIVDMCAAPGGKTSHIYELVRGE
ARIIAVDHSARKTERMRMELGRLGHTRIEVIRADSRYLDRILGSGVADYVLLDPPCTSLGVIPKIYDRKTLRDVANTAEY
QRQFLRAAAKLLKPGGVLVYSTCTMTLMENEENTQYAIEKLGLNPEEPQYHRFSRGLNQAWYAQRSHPHVHRTTGYYIAR
LRKKP

Sequences:

>Translated_405_residues
MPRVRNPAIQEEDIQEDIRAPPQLDYDAGLLRELRRVYGGALSAALQAILEPPARYYVRVNVLRADPGTVLDEMRAQGLE
VYADEELPEALWLPVRGPVEPRDTGCRLVVDKRAAESIMLGANVYAPGVVALDEACANPGAEVTVVSENGVPVANAVLAE
DYRRAMEEGRGLVAVNVRPRYRVPSLRDTVWWRRGVIYEQSLPSMYASRILDPEPGAVIVDMCAAPGGKTSHIYELVRGE
ARIIAVDHSARKTERMRMELGRLGHTRIEVIRADSRYLDRILGSGVADYVLLDPPCTSLGVIPKIYDRKTLRDVANTAEY
QRQFLRAAAKLLKPGGVLVYSTCTMTLMENEENTQYAIEKLGLNPEEPQYHRFSRGLNQAWYAQRSHPHVHRTTGYYIAR
LRKKP
>Mature_404_residues
PRVRNPAIQEEDIQEDIRAPPQLDYDAGLLRELRRVYGGALSAALQAILEPPARYYVRVNVLRADPGTVLDEMRAQGLEV
YADEELPEALWLPVRGPVEPRDTGCRLVVDKRAAESIMLGANVYAPGVVALDEACANPGAEVTVVSENGVPVANAVLAED
YRRAMEEGRGLVAVNVRPRYRVPSLRDTVWWRRGVIYEQSLPSMYASRILDPEPGAVIVDMCAAPGGKTSHIYELVRGEA
RIIAVDHSARKTERMRMELGRLGHTRIEVIRADSRYLDRILGSGVADYVLLDPPCTSLGVIPKIYDRKTLRDVANTAEYQ
RQFLRAAAKLLKPGGVLVYSTCTMTLMENEENTQYAIEKLGLNPEEPQYHRFSRGLNQAWYAQRSHPHVHRTTGYYIARL
RKKP

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI32698918, Length=365, Percent_Identity=33.1506849315069, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI76150625, Length=248, Percent_Identity=31.8548387096774, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI76150623, Length=248, Percent_Identity=31.8548387096774, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI23199998, Length=234, Percent_Identity=28.6324786324786, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI270288818, Length=238, Percent_Identity=28.1512605042017, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI8922322, Length=234, Percent_Identity=28.6324786324786, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI270288816, Length=234, Percent_Identity=28.6324786324786, Blast_Score=85, Evalue=9e-17,
Organism=Escherichia coli, GI2367212, Length=236, Percent_Identity=31.7796610169492, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081985, Length=229, Percent_Identity=31.0043668122271, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17536757, Length=220, Percent_Identity=34.0909090909091, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71998419, Length=227, Percent_Identity=24.2290748898678, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI115534021, Length=227, Percent_Identity=24.6696035242291, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324268, Length=210, Percent_Identity=30.952380952381, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319447, Length=187, Percent_Identity=29.9465240641711, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24668781, Length=436, Percent_Identity=29.5871559633028, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI21356513, Length=380, Percent_Identity=30.5263157894737, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI22024126, Length=252, Percent_Identity=32.1428571428571, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 45396; Mature: 45264

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS50890 PUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVRNPAIQEEDIQEDIRAPPQLDYDAGLLRELRRVYGGALSAALQAILEPPARYYVRV
CCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
NVLRADPGTVLDEMRAQGLEVYADEELPEALWLPVRGPVEPRDTGCRLVVDKRAAESIML
EEEECCCCHHHHHHHHCCCEEEECCCCCHHEECCCCCCCCCCCCCCEEEEECCCHHHEEE
GANVYAPGVVALDEACANPGAEVTVVSENGVPVANAVLAEDYRRAMEEGRGLVAVNVRPR
CCCCCCCCCEEEHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCC
YRVPSLRDTVWWRRGVIYEQSLPSMYASRILDPEPGAVIVDMCAAPGGKTSHIYELVRGE
CCCCCHHHHHHHHHCEEEHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHCCC
ARIIAVDHSARKTERMRMELGRLGHTRIEVIRADSRYLDRILGSGVADYVLLDPPCTSLG
EEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCCEEEECCCCCCCC
VIPKIYDRKTLRDVANTAEYQRQFLRAAAKLLKPGGVLVYSTCTMTLMENEENTQYAIEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCHHHHHHH
LGLNPEEPQYHRFSRGLNQAWYAQRSHPHVHRTTGYYIARLRKKP
HCCCCCCCHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHEECCCC
>Mature Secondary Structure 
PRVRNPAIQEEDIQEDIRAPPQLDYDAGLLRELRRVYGGALSAALQAILEPPARYYVRV
CCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
NVLRADPGTVLDEMRAQGLEVYADEELPEALWLPVRGPVEPRDTGCRLVVDKRAAESIML
EEEECCCCHHHHHHHHCCCEEEECCCCCHHEECCCCCCCCCCCCCCEEEEECCCHHHEEE
GANVYAPGVVALDEACANPGAEVTVVSENGVPVANAVLAEDYRRAMEEGRGLVAVNVRPR
CCCCCCCCCEEEHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCC
YRVPSLRDTVWWRRGVIYEQSLPSMYASRILDPEPGAVIVDMCAAPGGKTSHIYELVRGE
CCCCCHHHHHHHHHCEEEHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHCCC
ARIIAVDHSARKTERMRMELGRLGHTRIEVIRADSRYLDRILGSGVADYVLLDPPCTSLG
EEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCCEEEECCCCCCCC
VIPKIYDRKTLRDVANTAEYQRQFLRAAAKLLKPGGVLVYSTCTMTLMENEENTQYAIEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCHHHHHHH
LGLNPEEPQYHRFSRGLNQAWYAQRSHPHVHRTTGYYIARLRKKP
HCCCCCCCHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]