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The map label for this gene is rnr [C]

Identifier: 124025721

GI number: 124025721

Start: 939996

End: 941270

Strand: Direct

Name: rnr [C]

Synonym: NATL1_10141

Alternate gene names: 124025721

Gene position: 939996-941270 (Clockwise)

Preceding gene: 124025720

Following gene: 124025722

Centisome position: 50.41

GC content: 27.61

Gene sequence:

>1275_bases
ATGGGCACAAAAATAATAGAAGATGAAATAAAAGATTTAATATTCAGATCTAACACAAGTAATAATTTAAATTCTGCAGT
TAAAGATCTTAGCCATCTTAAAACATATACAATCGATGATTCTAAAACCGTAGAAATAGATGATGCAATTTCACTAGAAC
AAGTATCTGGTCAGAACAAGTTATGGATTCATATCGCATCCCCTGCTTCCTATATTGAATATCAATCAGGTATAGATGAA
AAAGCAAGAAAACTTGTCTCAACTGTTTATTTGTCTACCAATACCTATTACATGCTTCCCGAAGCTTTAATAAATAATGT
ATTCAGCCTAAGTGATAAAGAAAAGAGAGAATCATTAAGCTTAGGTGTTATCTTAAATGATGACGGTACTATTTCTTCTA
CTGAAATTGTTCAGAGTTTGATTCAAGTAGATTATCGCTTAGATTTTACAGAAGCTGATGAACTTATAGATTATGCGCCA
AAAGAAGAGATAGATTTAAGTCTTATATCAACCATTTTAGAAAGTAGAAAGAATTGGAGAAAGAATTTAGGTTCAATTGA
AATATTAGAATCTTATGGAAAAATAGTTGTTGACGATAAGATTCCCAACATAAAAATAATTGATCCAACATTATCAAGAC
AACTAATAAGTGAGGCTATGATCTTGTACGGAGATATTATTTCAAATTTTACTAAGCTAAATAAAATACCTGTTCCATAT
AGGGTTCAACAACGTTCAGATAAAGTAAGTAGAGATAATATTCAACTTTCTGATAATAAAATTTTATATAATTTTTTACT
TAAGAAAACCATGGGTAAAACTTATTATTCTATAAATCCAATGCAACACGATAGTTTAGCATTAACATCTTATTTACATG
CTACATCTCCCATTAGAAGATATGCTGACTTGTTAGTTCACTATCAATTAAATAGATTTCTTAATAATAAAGTTCTCATA
TCTAAGGATGATGTTCAACAGATTATTCATGAGATTAATAATCAAGGAAGACAAAATATCATGAGATTTAGAGAAGATCA
AAAATATTGGCTAGGTATATGGTTCGAAAATAATACGTTTAATGAATATAGTGTGATATTGCTTAATTGGATAAATAGGT
ATAAAAATATCTGTCTTCTATACTTTGTCGATTATAATTTTTCTACAATATCCAATTTGCATTCAAAATTAAATATAAAT
ATCGGAGACAATTTTAACGTTAAAAATACTAACCATGATAATAACGATATGAATTATTTTGAGATAATTCAATGA

Upstream 100 bases:

>100_bases
ACTTAACAACAGCGGTTAAAAGAGCAAGAATTATTGCCTTACTCCCCTTTGTTAATCCAGAAGGATAGTTATATATTTTT
AATATTCTATTAAAAATAGA

Downstream 100 bases:

>100_bases
TTAATATTAACTATAAACATAGAAGTGCAAAAGCCTTAAAAATATAATATAATAAACAGAATATGTAATGAATATGAAAT
ACACAATTACAACACCACTA

Product: ribonuclease II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MGTKIIEDEIKDLIFRSNTSNNLNSAVKDLSHLKTYTIDDSKTVEIDDAISLEQVSGQNKLWIHIASPASYIEYQSGIDE
KARKLVSTVYLSTNTYYMLPEALINNVFSLSDKEKRESLSLGVILNDDGTISSTEIVQSLIQVDYRLDFTEADELIDYAP
KEEIDLSLISTILESRKNWRKNLGSIEILESYGKIVVDDKIPNIKIIDPTLSRQLISEAMILYGDIISNFTKLNKIPVPY
RVQQRSDKVSRDNIQLSDNKILYNFLLKKTMGKTYYSINPMQHDSLALTSYLHATSPIRRYADLLVHYQLNRFLNNKVLI
SKDDVQQIIHEINNQGRQNIMRFREDQKYWLGIWFENNTFNEYSVILLNWINRYKNICLLYFVDYNFSTISNLHSKLNIN
IGDNFNVKNTNHDNNDMNYFEIIQ

Sequences:

>Translated_424_residues
MGTKIIEDEIKDLIFRSNTSNNLNSAVKDLSHLKTYTIDDSKTVEIDDAISLEQVSGQNKLWIHIASPASYIEYQSGIDE
KARKLVSTVYLSTNTYYMLPEALINNVFSLSDKEKRESLSLGVILNDDGTISSTEIVQSLIQVDYRLDFTEADELIDYAP
KEEIDLSLISTILESRKNWRKNLGSIEILESYGKIVVDDKIPNIKIIDPTLSRQLISEAMILYGDIISNFTKLNKIPVPY
RVQQRSDKVSRDNIQLSDNKILYNFLLKKTMGKTYYSINPMQHDSLALTSYLHATSPIRRYADLLVHYQLNRFLNNKVLI
SKDDVQQIIHEINNQGRQNIMRFREDQKYWLGIWFENNTFNEYSVILLNWINRYKNICLLYFVDYNFSTISNLHSKLNIN
IGDNFNVKNTNHDNNDMNYFEIIQ
>Mature_423_residues
GTKIIEDEIKDLIFRSNTSNNLNSAVKDLSHLKTYTIDDSKTVEIDDAISLEQVSGQNKLWIHIASPASYIEYQSGIDEK
ARKLVSTVYLSTNTYYMLPEALINNVFSLSDKEKRESLSLGVILNDDGTISSTEIVQSLIQVDYRLDFTEADELIDYAPK
EEIDLSLISTILESRKNWRKNLGSIEILESYGKIVVDDKIPNIKIIDPTLSRQLISEAMILYGDIISNFTKLNKIPVPYR
VQQRSDKVSRDNIQLSDNKILYNFLLKKTMGKTYYSINPMQHDSLALTSYLHATSPIRRYADLLVHYQLNRFLNNKVLIS
KDDVQQIIHEINNQGRQNIMRFREDQKYWLGIWFENNTFNEYSVILLNWINRYKNICLLYFVDYNFSTISNLHSKLNINI
GDNFNVKNTNHDNNDMNYFEIIQ

Specific function: 3'-5'Exoribonuclease That Participates In An Essential Cell Function. Acts Nonspecifically On Poly(A), Poly(U) And Ribosomal RNAs. Required For The Expression Of VIrulence Genes In Enteroinvasive Strains Of E.Coli. [C]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonuclease II (RNB) family [H]

Homologues:

Organism=Homo sapiens, GI19115966, Length=379, Percent_Identity=24.5382585751979, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI219521928, Length=379, Percent_Identity=24.5382585751979, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87082383, Length=365, Percent_Identity=24.1095890410959, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787542, Length=364, Percent_Identity=23.0769230769231, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI212645896, Length=346, Percent_Identity=26.3005780346821, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323943, Length=370, Percent_Identity=25.4054054054054, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001900
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00773 RNB [H]

EC number: 3.1.13.1

Molecular weight: Translated: 49280; Mature: 49148

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTKIIEDEIKDLIFRSNTSNNLNSAVKDLSHLKTYTIDDSKTVEIDDAISLEQVSGQNK
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEECCCCEEEECCCCCHHHHCCCCE
LWIHIASPASYIEYQSGIDEKARKLVSTVYLSTNTYYMLPEALINNVFSLSDKEKRESLS
EEEEECCCHHHHHHHCCCCHHHHHHHHHHEEECCEEEECHHHHHHHHHCCCCHHHHCCEE
LGVILNDDGTISSTEIVQSLIQVDYRLDFTEADELIDYAPKEEIDLSLISTILESRKNWR
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KNLGSIEILESYGKIVVDDKIPNIKIIDPTLSRQLISEAMILYGDIISNFTKLNKIPVPY
HCCCCCHHHHHCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
RVQQRSDKVSRDNIQLSDNKILYNFLLKKTMGKTYYSINPMQHDSLALTSYLHATSPIRR
EECCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHH
YADLLVHYQLNRFLNNKVLISKDDVQQIIHEINNQGRQNIMRFREDQKYWLGIWFENNTF
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEEECCCC
NEYSVILLNWINRYKNICLLYFVDYNFSTISNLHSKLNINIGDNFNVKNTNHDNNDMNYF
CCHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCEE
EIIQ
EEEC
>Mature Secondary Structure 
GTKIIEDEIKDLIFRSNTSNNLNSAVKDLSHLKTYTIDDSKTVEIDDAISLEQVSGQNK
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEECCCCEEEECCCCCHHHHCCCCE
LWIHIASPASYIEYQSGIDEKARKLVSTVYLSTNTYYMLPEALINNVFSLSDKEKRESLS
EEEEECCCHHHHHHHCCCCHHHHHHHHHHEEECCEEEECHHHHHHHHHCCCCHHHHCCEE
LGVILNDDGTISSTEIVQSLIQVDYRLDFTEADELIDYAPKEEIDLSLISTILESRKNWR
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KNLGSIEILESYGKIVVDDKIPNIKIIDPTLSRQLISEAMILYGDIISNFTKLNKIPVPY
HCCCCCHHHHHCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
RVQQRSDKVSRDNIQLSDNKILYNFLLKKTMGKTYYSINPMQHDSLALTSYLHATSPIRR
EECCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHH
YADLLVHYQLNRFLNNKVLISKDDVQQIIHEINNQGRQNIMRFREDQKYWLGIWFENNTF
HHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEEECCCC
NEYSVILLNWINRYKNICLLYFVDYNFSTISNLHSKLNINIGDNFNVKNTNHDNNDMNYF
CCHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCEE
EIIQ
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]