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The map label for this gene is trpD

Identifier: 124025634

GI number: 124025634

Start: 854992

End: 856029

Strand: Direct

Name: trpD

Synonym: NATL1_09271

Alternate gene names: 124025634

Gene position: 854992-856029 (Clockwise)

Preceding gene: 124025633

Following gene: 124025635

Centisome position: 45.85

GC content: 37.09

Gene sequence:

>1038_bases
ATGACCATTTTAAATCCTATAACTTTTCCAGTAATTCTTGAATCACTTCTTGCTTCCAATGATTTAACTGAAGAGCAATC
TAAATTTTTAATGAATTCATGGCTTGAAAATAAAATTGAACCAGTTCAAACGGGGGCATTTTTAGCAGCATTAAGAGCAA
AGGGTGTTTCTGGTGATGAACTTTCGGCAATGGCAAAAATCCTTCAAGATGCTTCAACCACTCCATCAGATCTACCATCT
TTTGATTTGGTTGATACATGTGGAACTGGCGGGGATGGAGCGAACACTTTTAATATTTCTACAGGAGTTGCCTTCGTATC
AGCGGCTTTAGGGGTGAAAATTGCTAAACATGGAAATCGAAGTGCAAGTGGCAAGGTTGGATCAGCTGACGTATTAGAAA
ATTTAGGATTACCTTTAAATGTTTCCTCCGGGAAAGTTGTTGAAGCTTTAAAGAAGTTAGGTATTACATTTCTTTTTGCT
CCTTCTTGGCATCCTTCATTGGTAAATCTTGCTCCTTTAAGAAAAAGCTTAGGAGTCAGAACCATCTTCAATTTACTGGG
TCCATTGGTTAACCCACTTAGACCAAAGTCTCAAGTATTGGGAGTAGCCAAAGCTGATTTGCTTGATCCAATGTCAGTTG
CTTTAAAAGGAATGGGACTTAAAAGAGCTGTTGTGGTTCATGGAGCAGGAGGTCTTGATGAGGCTTCACTAGCTGGAGCT
AATCAATTTAGGTTCTTAGACAAAGATGTTATTAGATCTGAAATTATTAAACCTGGTGATCTTGGACTTACTCAAATCTC
TAATGAATCCTTAAAAGGTGATGATTTGAAAACTAATTCTCATATCTTAAAGTCTTTACTTAATGGAGAAGGAAATCAAT
ATCACAAAGAAGTCGTAGCATTAAATACCGCTCTGGTTTTATGGGTATCAGGAACTGAGGATGATTTATCTTCAGGCGTC
AAACGAGCATTAGATTGTTTGAATACAGATAAATCATGGCTCCTTTTCGAGCAATTAAGAGATTTTTTAGCCACTTAA

Upstream 100 bases:

>100_bases
ATTTTTTTATTTAAACAACTTCCATAGTTGATATATTAATGATTAAGTTATAAAAAATATTGTGCTTGGAACGCTTAACA
CTCAGGCATTTTTCTGATAA

Downstream 100 bases:

>100_bases
TTCTTTCAATCTGATAAACCCTATTCCTTATGTTTTTTGATACTGATAGCTCTGCAATTTTGTTATTAGAGGATGGGACA
TATTTTGAAGGATTATCTTT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTILNPITFPVILESLLASNDLTEEQSKFLMNSWLENKIEPVQTGAFLAALRAKGVSGDELSAMAKILQDASTTPSDLPS
FDLVDTCGTGGDGANTFNISTGVAFVSAALGVKIAKHGNRSASGKVGSADVLENLGLPLNVSSGKVVEALKKLGITFLFA
PSWHPSLVNLAPLRKSLGVRTIFNLLGPLVNPLRPKSQVLGVAKADLLDPMSVALKGMGLKRAVVVHGAGGLDEASLAGA
NQFRFLDKDVIRSEIIKPGDLGLTQISNESLKGDDLKTNSHILKSLLNGEGNQYHKEVVALNTALVLWVSGTEDDLSSGV
KRALDCLNTDKSWLLFEQLRDFLAT

Sequences:

>Translated_345_residues
MTILNPITFPVILESLLASNDLTEEQSKFLMNSWLENKIEPVQTGAFLAALRAKGVSGDELSAMAKILQDASTTPSDLPS
FDLVDTCGTGGDGANTFNISTGVAFVSAALGVKIAKHGNRSASGKVGSADVLENLGLPLNVSSGKVVEALKKLGITFLFA
PSWHPSLVNLAPLRKSLGVRTIFNLLGPLVNPLRPKSQVLGVAKADLLDPMSVALKGMGLKRAVVVHGAGGLDEASLAGA
NQFRFLDKDVIRSEIIKPGDLGLTQISNESLKGDDLKTNSHILKSLLNGEGNQYHKEVVALNTALVLWVSGTEDDLSSGV
KRALDCLNTDKSWLLFEQLRDFLAT
>Mature_344_residues
TILNPITFPVILESLLASNDLTEEQSKFLMNSWLENKIEPVQTGAFLAALRAKGVSGDELSAMAKILQDASTTPSDLPSF
DLVDTCGTGGDGANTFNISTGVAFVSAALGVKIAKHGNRSASGKVGSADVLENLGLPLNVSSGKVVEALKKLGITFLFAP
SWHPSLVNLAPLRKSLGVRTIFNLLGPLVNPLRPKSQVLGVAKADLLDPMSVALKGMGLKRAVVVHGAGGLDEASLAGAN
QFRFLDKDVIRSEIIKPGDLGLTQISNESLKGDDLKTNSHILKSLLNGEGNQYHKEVVALNTALVLWVSGTEDDLSSGVK
RALDCLNTDKSWLLFEQLRDFLAT

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=327, Percent_Identity=37.6146788990826, Blast_Score=201, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6320561, Length=332, Percent_Identity=27.710843373494, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_PROM1 (A2C1X5)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014750.1
- ProteinModelPortal:   A2C1X5
- SMR:   A2C1X5
- STRING:   A2C1X5
- GeneID:   4780028
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_09271
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   PMAR167555:NATL1_09271-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36596; Mature: 36464

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILNPITFPVILESLLASNDLTEEQSKFLMNSWLENKIEPVQTGAFLAALRAKGVSGDE
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHH
LSAMAKILQDASTTPSDLPSFDLVDTCGTGGDGANTFNISTGVAFVSAALGVKIAKHGNR
HHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCC
SASGKVGSADVLENLGLPLNVSSGKVVEALKKLGITFLFAPSWHPSLVNLAPLRKSLGVR
CCCCCCCCHHHHHHCCCCEECCCCHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHH
TIFNLLGPLVNPLRPKSQVLGVAKADLLDPMSVALKGMGLKRAVVVHGAGGLDEASLAGA
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEECCCCCCHHHHCCC
NQFRFLDKDVIRSEIIKPGDLGLTQISNESLKGDDLKTNSHILKSLLNGEGNQYHKEVVA
HHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
LNTALVLWVSGTEDDLSSGVKRALDCLNTDKSWLLFEQLRDFLAT
EEEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TILNPITFPVILESLLASNDLTEEQSKFLMNSWLENKIEPVQTGAFLAALRAKGVSGDE
CCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHH
LSAMAKILQDASTTPSDLPSFDLVDTCGTGGDGANTFNISTGVAFVSAALGVKIAKHGNR
HHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCC
SASGKVGSADVLENLGLPLNVSSGKVVEALKKLGITFLFAPSWHPSLVNLAPLRKSLGVR
CCCCCCCCHHHHHHCCCCEECCCCHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHH
TIFNLLGPLVNPLRPKSQVLGVAKADLLDPMSVALKGMGLKRAVVVHGAGGLDEASLAGA
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEECCCCCCHHHHCCC
NQFRFLDKDVIRSEIIKPGDLGLTQISNESLKGDDLKTNSHILKSLLNGEGNQYHKEVVA
HHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
LNTALVLWVSGTEDDLSSGVKRALDCLNTDKSWLLFEQLRDFLAT
EEEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA