Click here to switch to the map view.

The map label for this gene is spsE

Identifier: 124025579

GI number: 124025579

Start: 809477

End: 810505

Strand: Direct

Name: spsE

Synonym: NATL1_08721

Alternate gene names: NA

Gene position: 809477-810505 (Clockwise)

Preceding gene: 124025574

Following gene: 124025580

Centisome position: 43.41

GC content: 32.75

Gene sequence:

>1029_bases
ATGAATATCAACGGTAGAGAAATTAATGAGAAAAACACTCCCTTAATAATAGCGGAACTAGGAATTAATCACGGTGGAGA
TATAGATATAGCAAAAAATATGGTAACTTTAGCAGCTTCATCAGGAGCAGAGTGCATTAAACATCAAACACATTTTGTGG
AAGATGAAATGACAGAAGAAGCGAAAGATATTTACCCTCCCAATGCTACTGAATCCATATGGGATGTTATAAAAAAATCA
TCTCTTAATAAAGATGAAGAAATAGAATTAAAAAAATATACAGAGGATTTAGGATTAATATATATATCAACTCCTTTCTC
AAGAGCTGCTGCTGATTTTCTAAATGATATTAATATACCTGCCTTTAAAATAGGATCGGGTGAGGCTAGTAATATCCCGC
TTATAAGACATATATCATCATTTGGAAAGCCTATTATTTTATCAACAGGAATGCATTCTTTAGAGCAAATAATTGAACCA
GTTAATATTTTCAAGAAAAACAAAATAGATTTCGCCCTTCTAGAATGTACGAATTCTTACCCTTCACCACCTGAAATAGT
ATCTCTCCAAGGAATAAAAGATTTAAAAAAAGCTTTTCCTGAGGCAATTGTTGGTTTTTCTGATCATTCGATAGGGCCTT
ACATATCATTGGGAGCAGTTGCATTAGGGGCTTGTATTATTGAAAGACACTTTACTGACTCAAGGTATAGAGAAGGTCCT
GACATCTCTTGTTCAATGGATCCCCTAGAACTAAGACTTTTAGTAGATAGGTCTAAAGAAATTTTTACAGCGATAAATAA
TCCAAAAGAAAGAACTCTTCAGGAAGAAGATGTTTACAAATTTGCGAGAGGTACTATTGTAGCTGATAGAGAAATTAAAA
AAGGAACAATTATCGCAGAAAAAGATATATGGGCAAGACGTCCTGGTAACGGTGAAATAGCAGCTGCATTCTATGATAAT
ATCTTGGGAAGAAAAACGAAAAAAGATATAAAATATAATCAACAATTAAGATGGAAAGATCTTATTTAA

Upstream 100 bases:

>100_bases
CAAAGAATTAAATCCTTTTCAAGAAGAATTGCTACTATTTTTCATTTATAGACTATTTGCTATAAAAATAATTAACAACT
AAGGTTAATCATGAACTTTT

Downstream 100 bases:

>100_bases
ATTTCTAAATTTTAAACAAATCGATAAAAATATTGCAGAGAATTTTACCTACATCAATTAATAATTTAGGTTCACAAATT
CATAGGTTCAGAACTTAAGA

Product: ialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNINGREINEKNTPLIIAELGINHGGDIDIAKNMVTLAASSGAECIKHQTHFVEDEMTEEAKDIYPPNATESIWDVIKKS
SLNKDEEIELKKYTEDLGLIYISTPFSRAAADFLNDINIPAFKIGSGEASNIPLIRHISSFGKPIILSTGMHSLEQIIEP
VNIFKKNKIDFALLECTNSYPSPPEIVSLQGIKDLKKAFPEAIVGFSDHSIGPYISLGAVALGACIIERHFTDSRYREGP
DISCSMDPLELRLLVDRSKEIFTAINNPKERTLQEEDVYKFARGTIVADREIKKGTIIAEKDIWARRPGNGEIAAAFYDN
ILGRKTKKDIKYNQQLRWKDLI

Sequences:

>Translated_342_residues
MNINGREINEKNTPLIIAELGINHGGDIDIAKNMVTLAASSGAECIKHQTHFVEDEMTEEAKDIYPPNATESIWDVIKKS
SLNKDEEIELKKYTEDLGLIYISTPFSRAAADFLNDINIPAFKIGSGEASNIPLIRHISSFGKPIILSTGMHSLEQIIEP
VNIFKKNKIDFALLECTNSYPSPPEIVSLQGIKDLKKAFPEAIVGFSDHSIGPYISLGAVALGACIIERHFTDSRYREGP
DISCSMDPLELRLLVDRSKEIFTAINNPKERTLQEEDVYKFARGTIVADREIKKGTIIAEKDIWARRPGNGEIAAAFYDN
ILGRKTKKDIKYNQQLRWKDLI
>Mature_342_residues
MNINGREINEKNTPLIIAELGINHGGDIDIAKNMVTLAASSGAECIKHQTHFVEDEMTEEAKDIYPPNATESIWDVIKKS
SLNKDEEIELKKYTEDLGLIYISTPFSRAAADFLNDINIPAFKIGSGEASNIPLIRHISSFGKPIILSTGMHSLEQIIEP
VNIFKKNKIDFALLECTNSYPSPPEIVSLQGIKDLKKAFPEAIVGFSDHSIGPYISLGAVALGACIIERHFTDSRYREGP
DISCSMDPLELRLLVDRSKEIFTAINNPKERTLQEEDVYKFARGTIVADREIKKGTIIAEKDIWARRPGNGEIAAAFYDN
ILGRKTKKDIKYNQQLRWKDLI

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=301, Percent_Identity=33.5548172757475, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI21357081, Length=258, Percent_Identity=34.4961240310078, Blast_Score=162, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38261; Mature: 38261

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINGREINEKNTPLIIAELGINHGGDIDIAKNMVTLAASSGAECIKHQTHFVEDEMTEE
CCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHH
AKDIYPPNATESIWDVIKKSSLNKDEEIELKKYTEDLGLIYISTPFSRAAADFLNDINIP
HHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCC
AFKIGSGEASNIPLIRHISSFGKPIILSTGMHSLEQIIEPVNIFKKNKIDFALLECTNSY
EEEECCCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
PSPPEIVSLQGIKDLKKAFPEAIVGFSDHSIGPYISLGAVALGACIIERHFTDSRYREGP
CCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHCCCC
DISCSMDPLELRLLVDRSKEIFTAINNPKERTLQEEDVYKFARGTIVADREIKKGTIIAE
CCCCCCCCEEEEEEECCCHHHHHHHCCHHHHCCCHHHHHHHHCCCEEECCCCCCCEEEEE
KDIWARRPGNGEIAAAFYDNILGRKTKKDIKYNQQLRWKDLI
CCHHHCCCCCCCEEHHHHHHHHCCCHHHHCCCCCCCCHHCCC
>Mature Secondary Structure
MNINGREINEKNTPLIIAELGINHGGDIDIAKNMVTLAASSGAECIKHQTHFVEDEMTEE
CCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHH
AKDIYPPNATESIWDVIKKSSLNKDEEIELKKYTEDLGLIYISTPFSRAAADFLNDINIP
HHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCC
AFKIGSGEASNIPLIRHISSFGKPIILSTGMHSLEQIIEPVNIFKKNKIDFALLECTNSY
EEEECCCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
PSPPEIVSLQGIKDLKKAFPEAIVGFSDHSIGPYISLGAVALGACIIERHFTDSRYREGP
CCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHCCCC
DISCSMDPLELRLLVDRSKEIFTAINNPKERTLQEEDVYKFARGTIVADREIKKGTIIAE
CCCCCCCCEEEEEEECCCHHHHHHHCCHHHHCCCHHHHHHHHCCCEEECCCCCCCEEEEE
KDIWARRPGNGEIAAAFYDNILGRKTKKDIKYNQQLRWKDLI
CCHHHCCCCCCCEEHHHHHHHHCCCHHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]