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The map label for this gene is purQ [H]

Identifier: 124025526

GI number: 124025526

Start: 753353

End: 754006

Strand: Direct

Name: purQ [H]

Synonym: NATL1_08191

Alternate gene names: 124025526

Gene position: 753353-754006 (Clockwise)

Preceding gene: 124025525

Following gene: 124025544

Centisome position: 40.4

GC content: 35.17

Gene sequence:

>654_bases
ATGAATATTGGAATTATTGTTTTCCCTGGATCGAACTGCGATAGAGACGTCAGGTGGGCTACTGAAGGATGCCTGGGAAT
TCCTACAAGCTTTCTATGGCATGAAACTACTGACTTAAGTGGTTATGACGCAATTGTTATTCCAGGGGGGTTTAGTTATG
GAGATTATTTACGTTGTGGAGCAATAGCAAGATTCGCACCTGTTTTAAATTCTTTAATCTCTTTTGTTGATAAAGGTGGA
AAAGTTCTTGGTATTTGTAATGGGTTTCAAATACTTACTGAACTTGGTCTCTTGCAAGGAGCTTTGACAAGAAATAATAA
TCTACATTTTATTTGTGATAGTGCAAATTTATCTATTGAAAGCACAAAATCATCTTGGATGAAAAATTATAAAAAACATG
ATTCTATTTCACTTCCTATCGCTCATGGAGAAGGGAGATATCAATGTAGCAATGACGTCTTGAAAAAATTGCAAGATGAT
GATTCTATTGCTCTAAGATACGCTCATAACCCAAATGGATCTATCAATGATATTGCTGGAATTACAAATAAAAAAGGAAA
TGTTTTGGGGATGATGCCACATCCTGAAAGAGCTTGTGATGATGCATTAGGTAATATTGATGGGAAGTCAATTCTTAGTA
CACTTCTTTCTTGA

Upstream 100 bases:

>100_bases
AAGATTGAGTTAATGAGTGATCGATTGCTTGCAAACCCTGTTATTGAGGACTGGTCTTTGGAATTTAAGGACGAGCAGAA
AACTCTTACAAACTAAATAA

Downstream 100 bases:

>100_bases
ATTTATAAATCAAGGCATTAAAAAAGCTGCTATCAAAATGAGAGATAGCAGCTTTTTGTTAGCTTTTTTAGATTAGTACT
TGTATCCAGCTACAAATAAT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNIGIIVFPGSNCDRDVRWATEGCLGIPTSFLWHETTDLSGYDAIVIPGGFSYGDYLRCGAIARFAPVLNSLISFVDKGG
KVLGICNGFQILTELGLLQGALTRNNNLHFICDSANLSIESTKSSWMKNYKKHDSISLPIAHGEGRYQCSNDVLKKLQDD
DSIALRYAHNPNGSINDIAGITNKKGNVLGMMPHPERACDDALGNIDGKSILSTLLS

Sequences:

>Translated_217_residues
MNIGIIVFPGSNCDRDVRWATEGCLGIPTSFLWHETTDLSGYDAIVIPGGFSYGDYLRCGAIARFAPVLNSLISFVDKGG
KVLGICNGFQILTELGLLQGALTRNNNLHFICDSANLSIESTKSSWMKNYKKHDSISLPIAHGEGRYQCSNDVLKKLQDD
DSIALRYAHNPNGSINDIAGITNKKGNVLGMMPHPERACDDALGNIDGKSILSTLLS
>Mature_217_residues
MNIGIIVFPGSNCDRDVRWATEGCLGIPTSFLWHETTDLSGYDAIVIPGGFSYGDYLRCGAIARFAPVLNSLISFVDKGG
KVLGICNGFQILTELGLLQGALTRNNNLHFICDSANLSIESTKSSWMKNYKKHDSISLPIAHGEGRYQCSNDVLKKLQDD
DSIALRYAHNPNGSINDIAGITNKKGNVLGMMPHPERACDDALGNIDGKSILSTLLS

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=187, Percent_Identity=33.1550802139037, Blast_Score=74, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6321498, Length=182, Percent_Identity=31.3186813186813, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582111, Length=202, Percent_Identity=31.1881188118812, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24582109, Length=202, Percent_Identity=31.1881188118812, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17137292, Length=202, Percent_Identity=31.1881188118812, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23506; Mature: 23506

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGIIVFPGSNCDRDVRWATEGCLGIPTSFLWHETTDLSGYDAIVIPGGFSYGDYLRCG
CCEEEEEECCCCCCCCCHHHCCCCCCCCCHHHEECCCCCCCCCEEEECCCCCCCCHHHHH
AIARFAPVLNSLISFVDKGGKVLGICNGFQILTELGLLQGALTRNNNLHFICDSANLSIE
HHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEE
STKSSWMKNYKKHDSISLPIAHGEGRYQCSNDVLKKLQDDDSIALRYAHNPNGSINDIAG
HHHHHHHHHHHCCCCEEEEEECCCCCEECHHHHHHHHCCCCCEEEEEEECCCCCCHHHCC
ITNKKGNVLGMMPHPERACDDALGNIDGKSILSTLLS
CCCCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MNIGIIVFPGSNCDRDVRWATEGCLGIPTSFLWHETTDLSGYDAIVIPGGFSYGDYLRCG
CCEEEEEECCCCCCCCCHHHCCCCCCCCCHHHEECCCCCCCCCEEEECCCCCCCCHHHHH
AIARFAPVLNSLISFVDKGGKVLGICNGFQILTELGLLQGALTRNNNLHFICDSANLSIE
HHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEE
STKSSWMKNYKKHDSISLPIAHGEGRYQCSNDVLKKLQDDDSIALRYAHNPNGSINDIAG
HHHHHHHHHHHCCCCEEEEEECCCCCEECHHHHHHHHCCCCCEEEEEEECCCCCCHHHCC
ITNKKGNVLGMMPHPERACDDALGNIDGKSILSTLLS
CCCCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA