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The map label for this gene is recG [H]

Identifier: 124025499

GI number: 124025499

Start: 723288

End: 725828

Strand: Direct

Name: recG [H]

Synonym: NATL1_07921

Alternate gene names: 124025499

Gene position: 723288-725828 (Clockwise)

Preceding gene: 124025498

Following gene: 124025500

Centisome position: 38.79

GC content: 35.69

Gene sequence:

>2541_bases
ATGGTGGAAGGATACAACAAAAATTTAACCAGCTCTGATTCGAAACCCACTCCCGATCGTCAATCAAGTGAATTAACAAC
TTGGATTCGATCTTTGCAACAAGCTTTAACAGTTGAGGTCGATCATGGCTTTACTAATATTCAAGGCAGAACAAATAAAT
TTTCTTATTTTGTAAGTGGATATTTATTGAGAGGTCCTTCTACAGCTGTTAACGAATTAGATTTTTCTAGATTACAGGAA
TTAGCTTTAGATTATGAAAAATATCAAACTATGTCTACAGACGATAGACGTAAAATAATAGTTCAAACCAGACAGGCTCT
TCATAACCTTTTTAAATATAAGGAAGGTGAAGAGAGAGCCGAGCCTAGCAAATTAAAAATAAGAAGATCTCAAGAATCTA
CTTTGCATAAGAGAAGTTCTTCTGCATATTCACTAAGTTTACAAAGTACGATTTCTTCTGTTAAAGGTGTTGGCTCCAAA
CAAGCTGAGAGATTGTCTACATTAGGTCTTATTTTGATTCGTGATCTTATTAATTATTTTCCTCGTGATTATGTTGATTA
CTCTTCATTGAAAACGATAGATAAAACTCAAGCAGGTCAGAATGTAACGATTGTGGCAAAAGTTAGACGATGCAGTTCAT
TTAAAAGTCCTAAAAATCCAAATCTTTCAATTCTTGAGTTGTTTATAAAAGATAAGACAGGAGGAATGAAAATTACTAGG
TTTTTCGCAGGTCGTCGGAGTAGCAGTATTGCGTATGTGAAATCTCAACAAAGTTTGTATCCTGTTGGTGCAACTGTTGC
GGTAAGTGGGTTAGTTAAGGAAAGTAAATATGGTAAATCATTAAATGACCCTTTAATAGAAATTATCGATAGTCCCAACG
GTTATTTGAAATCTAGAACTATTGGTCAGATATTGCCTGTGTACTCTTTAACGGAAGGTATTACGGCTGATAAGTTCAGA
GATCTAATACAATCGATACTTTATTTGACATCAAATATTAAAGATCCATTGCCGAAAGAGACATTAAATAGGCTTGATTT
ACCTTATCGGAAAGAAGCTTTTTTTCATATTCATAATCCTGCGAATTCAAAGACCTTAGCTAAAGCAAAAAGAAGAATTG
TATTTGATGAGTTTTTATTATTGCAGCTTAGTCTTCTTTTAAGACGTGATTTACATAAGAAATCTGATTCTCCTCAACTA
AGTATTGAGCCAAATATTAATAGCCTAGTTGGGAAATTCCTGAGTATTCTTCCATTCTCTCTGACTAATGCTCAAAGAAG
GGTTTTAAAGGAAATTGAATCAGACATAGTCAAAGCAGAGCCAATGTCTCGACTATTACAAGGCGATGTTGGTAGTGGAA
AAACTGTTATCGCTATTTCAGCACTTCTCACTGCAGTTCAATCAGGATGGCAGGGTGCTTTTATGGCTCCAACTGAGGTA
CTCGCATCACAACACTTTCAAACACTAAGTAAATGGATTCCTCAACTTGAGATTAATGTTGATTTGTTAACTGGCTCTAC
GCCAAAGTCTCGTCGGAAACAAATTCTGACTGATTTAGTAAATGGCTCTACAAAAATTCTTGTAGGAACTCATGCCCTAT
TTGAAGACCCAGTTGTCTTCGAACGACTTGGCCTTGTAGTTGTCGATGAGCAACATCGCTTTGGTGTTAAGCAGAGGAAT
AAATTGTTGAACAAAGGTTTACAACCTCACTTGCTAACGATGACGGCTACACCCATTCCCAGAACCTTAGCACTTACTTT
GCATGGCGATCTAGATGTTAGTCAATTAGATGAGCTTCCTCCTGGTCGAACTCCCATTAATACTCAGCTGATATCACCTA
AAGATAAAAAGTATGCATATGATTTGATCAGGAGTGAAATTAAGAAAGGACATCAAATCTATGTTGTATTACCTTTAATT
GAAGAGTCTGAGAAACTAGAACTTAGTTCAGCTGTAGACGTACACCATCAATTGTCTACTGAAATTTTTTCAGAATTTAA
TGTTGAATTACTTCATGGCAAAATGAAAAGTGTAGAAAAGCAAGAGGTTATTCAGAATTTTATTAATAAAAAAAGCGATA
TATTGGTATCTACTACGGTTATTGAAGTAGGTGTTGATGTCCCAAATGCAAGTGTAATGTTGATAGAAGATTCTGATCGT
TTTGGTTTAGCTCAATTGCATCAACTAAGGGGCCGAGTAGGAAGAGGAGCTACCAAGTCATACTGTCTCCTGAGTCATCA
AAATAAAAATAAATTATCTAGACAAAGACTGGACGTTCTTGTGAACTCTAATGACGGATTTGAAATTTCTGAAATTGATT
TGCGTTTTCGTGGACCTGGACAAGTCTTAGGTACTAAACAATCAGGCTTGCCTGACTTTGCTCTGGCATCATTAGCTGAT
GATGCTGATGTTCTTGAAATTGCACGAAAGGAGGCTCGAATTATTTTAGATTCCGATCCTCTGCTTTCAAACAACTCAAT
GCTTCGTTTGTCAATCAAAGAGCAGTGGGACAGACTAAAAATTGGTAATAAATTAAATTAA

Upstream 100 bases:

>100_bases
ATAGAACTAATATGAAACATTATCAAAATGTACTTTTAGGTATGATTAAACAACAACGTTACTGGCAAGGTCGCTCCATA
GCAGAAGAGGTTAATAAAAA

Downstream 100 bases:

>100_bases
CTTTTTGATGAGTCATTACTATTGAACTCATTCTTTTTGAAGGTAAGCTTAAGGAAAGAATTTTTGTGCGAATGAATTTT
TACCCTAATATTTTATACAA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 846; Mature: 846

Protein sequence:

>846_residues
MVEGYNKNLTSSDSKPTPDRQSSELTTWIRSLQQALTVEVDHGFTNIQGRTNKFSYFVSGYLLRGPSTAVNELDFSRLQE
LALDYEKYQTMSTDDRRKIIVQTRQALHNLFKYKEGEERAEPSKLKIRRSQESTLHKRSSSAYSLSLQSTISSVKGVGSK
QAERLSTLGLILIRDLINYFPRDYVDYSSLKTIDKTQAGQNVTIVAKVRRCSSFKSPKNPNLSILELFIKDKTGGMKITR
FFAGRRSSSIAYVKSQQSLYPVGATVAVSGLVKESKYGKSLNDPLIEIIDSPNGYLKSRTIGQILPVYSLTEGITADKFR
DLIQSILYLTSNIKDPLPKETLNRLDLPYRKEAFFHIHNPANSKTLAKAKRRIVFDEFLLLQLSLLLRRDLHKKSDSPQL
SIEPNINSLVGKFLSILPFSLTNAQRRVLKEIESDIVKAEPMSRLLQGDVGSGKTVIAISALLTAVQSGWQGAFMAPTEV
LASQHFQTLSKWIPQLEINVDLLTGSTPKSRRKQILTDLVNGSTKILVGTHALFEDPVVFERLGLVVVDEQHRFGVKQRN
KLLNKGLQPHLLTMTATPIPRTLALTLHGDLDVSQLDELPPGRTPINTQLISPKDKKYAYDLIRSEIKKGHQIYVVLPLI
EESEKLELSSAVDVHHQLSTEIFSEFNVELLHGKMKSVEKQEVIQNFINKKSDILVSTTVIEVGVDVPNASVMLIEDSDR
FGLAQLHQLRGRVGRGATKSYCLLSHQNKNKLSRQRLDVLVNSNDGFEISEIDLRFRGPGQVLGTKQSGLPDFALASLAD
DADVLEIARKEARIILDSDPLLSNNSMLRLSIKEQWDRLKIGNKLN

Sequences:

>Translated_846_residues
MVEGYNKNLTSSDSKPTPDRQSSELTTWIRSLQQALTVEVDHGFTNIQGRTNKFSYFVSGYLLRGPSTAVNELDFSRLQE
LALDYEKYQTMSTDDRRKIIVQTRQALHNLFKYKEGEERAEPSKLKIRRSQESTLHKRSSSAYSLSLQSTISSVKGVGSK
QAERLSTLGLILIRDLINYFPRDYVDYSSLKTIDKTQAGQNVTIVAKVRRCSSFKSPKNPNLSILELFIKDKTGGMKITR
FFAGRRSSSIAYVKSQQSLYPVGATVAVSGLVKESKYGKSLNDPLIEIIDSPNGYLKSRTIGQILPVYSLTEGITADKFR
DLIQSILYLTSNIKDPLPKETLNRLDLPYRKEAFFHIHNPANSKTLAKAKRRIVFDEFLLLQLSLLLRRDLHKKSDSPQL
SIEPNINSLVGKFLSILPFSLTNAQRRVLKEIESDIVKAEPMSRLLQGDVGSGKTVIAISALLTAVQSGWQGAFMAPTEV
LASQHFQTLSKWIPQLEINVDLLTGSTPKSRRKQILTDLVNGSTKILVGTHALFEDPVVFERLGLVVVDEQHRFGVKQRN
KLLNKGLQPHLLTMTATPIPRTLALTLHGDLDVSQLDELPPGRTPINTQLISPKDKKYAYDLIRSEIKKGHQIYVVLPLI
EESEKLELSSAVDVHHQLSTEIFSEFNVELLHGKMKSVEKQEVIQNFINKKSDILVSTTVIEVGVDVPNASVMLIEDSDR
FGLAQLHQLRGRVGRGATKSYCLLSHQNKNKLSRQRLDVLVNSNDGFEISEIDLRFRGPGQVLGTKQSGLPDFALASLAD
DADVLEIARKEARIILDSDPLLSNNSMLRLSIKEQWDRLKIGNKLN
>Mature_846_residues
MVEGYNKNLTSSDSKPTPDRQSSELTTWIRSLQQALTVEVDHGFTNIQGRTNKFSYFVSGYLLRGPSTAVNELDFSRLQE
LALDYEKYQTMSTDDRRKIIVQTRQALHNLFKYKEGEERAEPSKLKIRRSQESTLHKRSSSAYSLSLQSTISSVKGVGSK
QAERLSTLGLILIRDLINYFPRDYVDYSSLKTIDKTQAGQNVTIVAKVRRCSSFKSPKNPNLSILELFIKDKTGGMKITR
FFAGRRSSSIAYVKSQQSLYPVGATVAVSGLVKESKYGKSLNDPLIEIIDSPNGYLKSRTIGQILPVYSLTEGITADKFR
DLIQSILYLTSNIKDPLPKETLNRLDLPYRKEAFFHIHNPANSKTLAKAKRRIVFDEFLLLQLSLLLRRDLHKKSDSPQL
SIEPNINSLVGKFLSILPFSLTNAQRRVLKEIESDIVKAEPMSRLLQGDVGSGKTVIAISALLTAVQSGWQGAFMAPTEV
LASQHFQTLSKWIPQLEINVDLLTGSTPKSRRKQILTDLVNGSTKILVGTHALFEDPVVFERLGLVVVDEQHRFGVKQRN
KLLNKGLQPHLLTMTATPIPRTLALTLHGDLDVSQLDELPPGRTPINTQLISPKDKKYAYDLIRSEIKKGHQIYVVLPLI
EESEKLELSSAVDVHHQLSTEIFSEFNVELLHGKMKSVEKQEVIQNFINKKSDILVSTTVIEVGVDVPNASVMLIEDSDR
FGLAQLHQLRGRVGRGATKSYCLLSHQNKNKLSRQRLDVLVNSNDGFEISEIDLRFRGPGQVLGTKQSGLPDFALASLAD
DADVLEIARKEARIILDSDPLLSNNSMLRLSIKEQWDRLKIGNKLN

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=688, Percent_Identity=39.9709302325581, Blast_Score=420, Evalue=1e-118,
Organism=Escherichia coli, GI1787357, Length=383, Percent_Identity=34.4647519582245, Blast_Score=237, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 94910; Mature: 94910

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEGYNKNLTSSDSKPTPDRQSSELTTWIRSLQQALTVEVDHGFTNIQGRTNKFSYFVSG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCEECCCCCCCEEEEEEEE
YLLRGPSTAVNELDFSRLQELALDYEKYQTMSTDDRRKIIVQTRQALHNLFKYKEGEERA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
EPSKLKIRRSQESTLHKRSSSAYSLSLQSTISSVKGVGSKQAERLSTLGLILIRDLINYF
CCCHHEEECCHHHHHHHCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
PRDYVDYSSLKTIDKTQAGQNVTIVAKVRRCSSFKSPKNPNLSILELFIKDKTGGMKITR
CCCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHCCCCCCCCCCEEEEEEEECCCCCEEEEE
FFAGRRSSSIAYVKSQQSLYPVGATVAVSGLVKESKYGKSLNDPLIEIIDSPNGYLKSRT
EECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCH
IGQILPVYSLTEGITADKFRDLIQSILYLTSNIKDPLPKETLNRLDLPYRKEAFFHIHNP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEEEEEECC
ANSKTLAKAKRRIVFDEFLLLQLSLLLRRDLHKKSDSPQLSIEPNINSLVGKFLSILPFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHCCH
LTNAQRRVLKEIESDIVKAEPMSRLLQGDVGSGKTVIAISALLTAVQSGWQGAFMAPTEV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHH
LASQHFQTLSKWIPQLEINVDLLTGSTPKSRRKQILTDLVNGSTKILVGTHALFEDPVVF
HHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEHHHHCCCHHH
ERLGLVVVDEQHRFGVKQRNKLLNKGLQPHLLTMTATPIPRTLALTLHGDLDVSQLDELP
HHCCEEEECCHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHCCC
PGRTPINTQLISPKDKKYAYDLIRSEIKKGHQIYVVLPLIEESEKLELSSAVDVHHQLST
CCCCCCCCEEECCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEHHHHHHHHHHHHH
EIFSEFNVELLHGKMKSVEKQEVIQNFINKKSDILVSTTVIEVGVDVPNASVMLIEDSDR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEEEECCCC
FGLAQLHQLRGRVGRGATKSYCLLSHQNKNKLSRQRLDVLVNSNDGFEISEIDLRFRGPG
CCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHEEEECCCCCEEEEEEEEECCCC
QVLGTKQSGLPDFALASLADDADVLEIARKEARIILDSDPLLSNNSMLRLSIKEQWDRLK
CEECCCCCCCCHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCCCCEEEEEHHHHHHHHC
IGNKLN
CCCCCC
>Mature Secondary Structure
MVEGYNKNLTSSDSKPTPDRQSSELTTWIRSLQQALTVEVDHGFTNIQGRTNKFSYFVSG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCEECCCCCCCEEEEEEEE
YLLRGPSTAVNELDFSRLQELALDYEKYQTMSTDDRRKIIVQTRQALHNLFKYKEGEERA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
EPSKLKIRRSQESTLHKRSSSAYSLSLQSTISSVKGVGSKQAERLSTLGLILIRDLINYF
CCCHHEEECCHHHHHHHCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
PRDYVDYSSLKTIDKTQAGQNVTIVAKVRRCSSFKSPKNPNLSILELFIKDKTGGMKITR
CCCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHCCCCCCCCCCEEEEEEEECCCCCEEEEE
FFAGRRSSSIAYVKSQQSLYPVGATVAVSGLVKESKYGKSLNDPLIEIIDSPNGYLKSRT
EECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCH
IGQILPVYSLTEGITADKFRDLIQSILYLTSNIKDPLPKETLNRLDLPYRKEAFFHIHNP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEEEEEECC
ANSKTLAKAKRRIVFDEFLLLQLSLLLRRDLHKKSDSPQLSIEPNINSLVGKFLSILPFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHCCH
LTNAQRRVLKEIESDIVKAEPMSRLLQGDVGSGKTVIAISALLTAVQSGWQGAFMAPTEV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHH
LASQHFQTLSKWIPQLEINVDLLTGSTPKSRRKQILTDLVNGSTKILVGTHALFEDPVVF
HHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEHHHHCCCHHH
ERLGLVVVDEQHRFGVKQRNKLLNKGLQPHLLTMTATPIPRTLALTLHGDLDVSQLDELP
HHCCEEEECCHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHCCC
PGRTPINTQLISPKDKKYAYDLIRSEIKKGHQIYVVLPLIEESEKLELSSAVDVHHQLST
CCCCCCCCEEECCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEHHHHHHHHHHHHH
EIFSEFNVELLHGKMKSVEKQEVIQNFINKKSDILVSTTVIEVGVDVPNASVMLIEDSDR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEEEECCCC
FGLAQLHQLRGRVGRGATKSYCLLSHQNKNKLSRQRLDVLVNSNDGFEISEIDLRFRGPG
CCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHEEEECCCCCEEEEEEEEECCCC
QVLGTKQSGLPDFALASLADDADVLEIARKEARIILDSDPLLSNNSMLRLSIKEQWDRLK
CEECCCCCCCCHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCCCCCEEEEEHHHHHHHHC
IGNKLN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]