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The map label for this gene is nadA [H]

Identifier: 124025445

GI number: 124025445

Start: 679320

End: 680306

Strand: Reverse

Name: nadA [H]

Synonym: NATL1_07381

Alternate gene names: 124025445

Gene position: 680306-679320 (Counterclockwise)

Preceding gene: 124025447

Following gene: 124025444

Centisome position: 36.48

GC content: 34.35

Gene sequence:

>987_bases
TTGAATTGGAAACTAATTACTACTGTTTCCTATTACAAGACTGATATATCAGTCTCAAATAAAAACAAAAATCTCATTGA
TGAGATCAATTTTTTGCGTAAAAAAAGAAACGCTATAATTCTTGCCCATTACTACCAAGAGCCTGCGATACAGGATATTG
CAGATTTTATTGGAGATTCACTTGAATTATCCAGAAAAGCTTCAGAAACAAATGCAGAGGTTATTGTTTTTTGTGGCGTT
CATTTCATGGCCGAAACAGCAAAAATCTTGAGTCCAAATAAGATTGTTCTCCTTCCTGATTTTGATGCTGGATGCACACT
CGCAGATGATTGCCAACCTGATGACTTCCAAAAATTCTTAGACAAGCATCCTGATCATTTTGCCATTAGCTATGTAAATT
GCAGTGCAGCGGTAAAGGCAAAAAGTGACCTAATTTGCACAAGTAGTAACGCCGTTGATCTGGTAAACAAATTACCAAAA
GATTTACCTATTTTATTTTCACCAGATAGGAATCTTGGCAGATGGGTTGAACGTCAAAGTGGTAGAAAATTAACCTTGTG
GCCAGGCAGATGTCTTGTCCATGAAACTTTTAATGAAGAATCTCTTATAAAATTAAAAATCAAAAATCCAACCGCTGAAG
TTCTTGCCCATCCTGAATGTCAAGAGAATCTTTTAGATTTAGCAGATTTCATAGGTTCAACAAGCAAATTGCTAAATTAT
TCTCAAAATAGTAAGAAAGATAAATTTATCGTGCTAACTGAGCCAGGAATAATTCATCAAATGAGATTAAAAGACCCTTT
AAAGACATATATAGAAGTTCCTGGTCTAGATGGTTGTAGTTGCAATGAATGCCCATACATGAGAATGAATACCTTAGAAA
AAGTATTAAATTGCCTAAAAGAAATGAATCCAGAGTTGCACATGGACGAACAAATTAGATTAATGGCTTATAAGCCACTG
AAAAAAATGCTTGATATGAGTAATTGA

Upstream 100 bases:

>100_bases
AGATCATCCTGACTCCATGAGCCATGTAAATCCCCAGCGATAGCAATTCGGATATCTGTCAGATTTTTTTGGAAATTACC
CTCTATACTGCCCCAACACA

Downstream 100 bases:

>100_bases
TTTCAAGTGTGAATTTATCTCTTTTTATTGTTGTTTTAGGGGGAAGAAGTTTAAAAAGTAATATAGAAATACATGATGTA
AGATGGGTTTTAGGTGAAAA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MNWKLITTVSYYKTDISVSNKNKNLIDEINFLRKKRNAIILAHYYQEPAIQDIADFIGDSLELSRKASETNAEVIVFCGV
HFMAETAKILSPNKIVLLPDFDAGCTLADDCQPDDFQKFLDKHPDHFAISYVNCSAAVKAKSDLICTSSNAVDLVNKLPK
DLPILFSPDRNLGRWVERQSGRKLTLWPGRCLVHETFNEESLIKLKIKNPTAEVLAHPECQENLLDLADFIGSTSKLLNY
SQNSKKDKFIVLTEPGIIHQMRLKDPLKTYIEVPGLDGCSCNECPYMRMNTLEKVLNCLKEMNPELHMDEQIRLMAYKPL
KKMLDMSN

Sequences:

>Translated_328_residues
MNWKLITTVSYYKTDISVSNKNKNLIDEINFLRKKRNAIILAHYYQEPAIQDIADFIGDSLELSRKASETNAEVIVFCGV
HFMAETAKILSPNKIVLLPDFDAGCTLADDCQPDDFQKFLDKHPDHFAISYVNCSAAVKAKSDLICTSSNAVDLVNKLPK
DLPILFSPDRNLGRWVERQSGRKLTLWPGRCLVHETFNEESLIKLKIKNPTAEVLAHPECQENLLDLADFIGSTSKLLNY
SQNSKKDKFIVLTEPGIIHQMRLKDPLKTYIEVPGLDGCSCNECPYMRMNTLEKVLNCLKEMNPELHMDEQIRLMAYKPL
KKMLDMSN
>Mature_328_residues
MNWKLITTVSYYKTDISVSNKNKNLIDEINFLRKKRNAIILAHYYQEPAIQDIADFIGDSLELSRKASETNAEVIVFCGV
HFMAETAKILSPNKIVLLPDFDAGCTLADDCQPDDFQKFLDKHPDHFAISYVNCSAAVKAKSDLICTSSNAVDLVNKLPK
DLPILFSPDRNLGRWVERQSGRKLTLWPGRCLVHETFNEESLIKLKIKNPTAEVLAHPECQENLLDLADFIGSTSKLLNY
SQNSKKDKFIVLTEPGIIHQMRLKDPLKTYIEVPGLDGCSCNECPYMRMNTLEKVLNCLKEMNPELHMDEQIRLMAYKPL
KKMLDMSN

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=312, Percent_Identity=40.0641025641026, Blast_Score=248, Evalue=5e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37345; Mature: 37345

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWKLITTVSYYKTDISVSNKNKNLIDEINFLRKKRNAIILAHYYQEPAIQDIADFIGDS
CCCEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCC
LELSRKASETNAEVIVFCGVHFMAETAKILSPNKIVLLPDFDAGCTLADDCQPDDFQKFL
HHHHHHCCCCCCCEEEEECHHHHHHHHHHCCCCEEEEEECCCCCCEECCCCCCHHHHHHH
DKHPDHFAISYVNCSAAVKAKSDLICTSSNAVDLVNKLPKDLPILFSPDRNLGRWVERQS
HCCCCCEEEEEEECCEEEECCCCEEEECCCHHHHHHHCCCCCCEEECCCCCHHHHHHHCC
GRKLTLWPGRCLVHETFNEESLIKLKIKNPTAEVLAHPECQENLLDLADFIGSTSKLLNY
CCEEEECCCEEEEEECCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHCC
SQNSKKDKFIVLTEPGIIHQMRLKDPLKTYIEVPGLDGCSCNECPYMRMNTLEKVLNCLK
CCCCCCCEEEEEECCCCEEHHHHCCHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
EMNPELHMDEQIRLMAYKPLKKMLDMSN
HCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNWKLITTVSYYKTDISVSNKNKNLIDEINFLRKKRNAIILAHYYQEPAIQDIADFIGDS
CCCEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCC
LELSRKASETNAEVIVFCGVHFMAETAKILSPNKIVLLPDFDAGCTLADDCQPDDFQKFL
HHHHHHCCCCCCCEEEEECHHHHHHHHHHCCCCEEEEEECCCCCCEECCCCCCHHHHHHH
DKHPDHFAISYVNCSAAVKAKSDLICTSSNAVDLVNKLPKDLPILFSPDRNLGRWVERQS
HCCCCCEEEEEEECCEEEECCCCEEEECCCHHHHHHHCCCCCCEEECCCCCHHHHHHHCC
GRKLTLWPGRCLVHETFNEESLIKLKIKNPTAEVLAHPECQENLLDLADFIGSTSKLLNY
CCEEEECCCEEEEEECCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHCC
SQNSKKDKFIVLTEPGIIHQMRLKDPLKTYIEVPGLDGCSCNECPYMRMNTLEKVLNCLK
CCCCCCCEEEEEECCCCEEHHHHCCHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
EMNPELHMDEQIRLMAYKPLKKMLDMSN
HCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA