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The map label for this gene is metA [H]

Identifier: 124025415

GI number: 124025415

Start: 650713

End: 651606

Strand: Direct

Name: metA [H]

Synonym: NATL1_07081

Alternate gene names: 124025415

Gene position: 650713-651606 (Clockwise)

Preceding gene: 124025414

Following gene: 124025417

Centisome position: 34.9

GC content: 36.13

Gene sequence:

>894_bases
ATGGCATTAATACTTCCTCGTAGTTATCATAAAATATCATCGATAGAAAAAAATCATATTTCATGGATTGAGCCTGAATT
AGCAGAAAGACAGGATATTAGACCTCTTAGGATTGGGATATTAAATATTATGCCTTTGGGAAAACAATATGAATTTAATT
TATTGCACCCTTTAGGACTGTCTCCTCTACAAATAGAACCTATATGGATAAGATTGAAATCCCATTCATATAGGACTTGG
GATCTAGAACATCTGAAAAACTTATATGTTCATTGGGAGGAGGCAATGTCTCCCACTCCTCTTGATGGGTTGATTATTAC
TGGAGCACCTGTTGAGCACCTTCCGTTTGAAGAAGTTCATTATTGGAAGGAATTAGTAAATCTAATTGAGGAAGCAAAAT
TAAAATGTGCAAGTACCCTAGGATTGTGTTGGGCTGGTTTTGCAATGGCTTATATGGCTGGAGTTGAGAAAGAAAATTTT
AATAAAAAGCTTTTTGGTGTATATCCAATGAGAAGTCTTGTGCCTAGTCATTCTTTAATGGGAACACAGGATGATGAGTT
CTTCTGTCCCCAAAGTAGGCATGCTGGTTTACCAGATATCGAAATGGAAAAAGCAGAACAAAAAGGCAAGCTAAGATTAT
TGGCTCATGGAGAAAAAGTAGGCTACACAATTTTTGAAACACCTGACCAGAGGCAATTAATGCATTTAGGACATCCTGAA
TATAACGTTGATAGATTAAAATCTGAGATGGAAAGGGATAAGAAAAGAGGTGATGTACCTCCTCCAGAAAATTTTGATTT
GACCAAATCAAATACCTCATGGCGATCACATAGAAACTTATTATTTCAACAATGGTTGTGGTTCTGTTATCAACGTGTAA
GCCTGAGCGTTTAA

Upstream 100 bases:

>100_bases
ATGGTAAGAGTGTCTGTTGGTATAGAACATATTGATGATATCTTAGAGGATTTCGAGCAGGCTCTAAATTTAATTTAATT
TTCCAAGGAGGTATATAGAT

Downstream 100 bases:

>100_bases
CTTTTTTGGATTTTTAGGGATAAGCTTTTGGTTGAAAAAATTGACTATTTTAATGGTGGCATTATATTTTCTGGATCATG
AATGGCTTTGAGCTCTTCTA

Product: putative homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MALILPRSYHKISSIEKNHISWIEPELAERQDIRPLRIGILNIMPLGKQYEFNLLHPLGLSPLQIEPIWIRLKSHSYRTW
DLEHLKNLYVHWEEAMSPTPLDGLIITGAPVEHLPFEEVHYWKELVNLIEEAKLKCASTLGLCWAGFAMAYMAGVEKENF
NKKLFGVYPMRSLVPSHSLMGTQDDEFFCPQSRHAGLPDIEMEKAEQKGKLRLLAHGEKVGYTIFETPDQRQLMHLGHPE
YNVDRLKSEMERDKKRGDVPPPENFDLTKSNTSWRSHRNLLFQQWLWFCYQRVSLSV

Sequences:

>Translated_297_residues
MALILPRSYHKISSIEKNHISWIEPELAERQDIRPLRIGILNIMPLGKQYEFNLLHPLGLSPLQIEPIWIRLKSHSYRTW
DLEHLKNLYVHWEEAMSPTPLDGLIITGAPVEHLPFEEVHYWKELVNLIEEAKLKCASTLGLCWAGFAMAYMAGVEKENF
NKKLFGVYPMRSLVPSHSLMGTQDDEFFCPQSRHAGLPDIEMEKAEQKGKLRLLAHGEKVGYTIFETPDQRQLMHLGHPE
YNVDRLKSEMERDKKRGDVPPPENFDLTKSNTSWRSHRNLLFQQWLWFCYQRVSLSV
>Mature_296_residues
ALILPRSYHKISSIEKNHISWIEPELAERQDIRPLRIGILNIMPLGKQYEFNLLHPLGLSPLQIEPIWIRLKSHSYRTWD
LEHLKNLYVHWEEAMSPTPLDGLIITGAPVEHLPFEEVHYWKELVNLIEEAKLKCASTLGLCWAGFAMAYMAGVEKENFN
KKLFGVYPMRSLVPSHSLMGTQDDEFFCPQSRHAGLPDIEMEKAEQKGKLRLLAHGEKVGYTIFETPDQRQLMHLGHPEY
NVDRLKSEMERDKKRGDVPPPENFDLTKSNTSWRSHRNLLFQQWLWFCYQRVSLSV

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=299, Percent_Identity=34.4481605351171, Blast_Score=158, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 34698; Mature: 34566

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALILPRSYHKISSIEKNHISWIEPELAERQDIRPLRIGILNIMPLGKQYEFNLLHPLGL
CEEECCCCHHHHHHCCCCCCCCCCCHHHHHCCCCHHEEEEEHEECCCCCCCEEEECCCCC
SPLQIEPIWIRLKSHSYRTWDLEHLKNLYVHWEEAMSPTPLDGLIITGAPVEHLPFEEVH
CCEEEEEEEEEEECCCCCEECHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHH
YWKELVNLIEEAKLKCASTLGLCWAGFAMAYMAGVEKENFNKKLFGVYPMRSLVPSHSLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHCCCCCCC
GTQDDEFFCPQSRHAGLPDIEMEKAEQKGKLRLLAHGEKVGYTIFETPDQRQLMHLGHPE
CCCCCCEECCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCCEEEECCCCHHHHHHCCCCC
YNVDRLKSEMERDKKRGDVPPPENFDLTKSNTSWRSHRNLLFQQWLWFCYQRVSLSV
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALILPRSYHKISSIEKNHISWIEPELAERQDIRPLRIGILNIMPLGKQYEFNLLHPLGL
EEECCCCHHHHHHCCCCCCCCCCCHHHHHCCCCHHEEEEEHEECCCCCCCEEEECCCCC
SPLQIEPIWIRLKSHSYRTWDLEHLKNLYVHWEEAMSPTPLDGLIITGAPVEHLPFEEVH
CCEEEEEEEEEEECCCCCEECHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHH
YWKELVNLIEEAKLKCASTLGLCWAGFAMAYMAGVEKENFNKKLFGVYPMRSLVPSHSLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHCCCCCCC
GTQDDEFFCPQSRHAGLPDIEMEKAEQKGKLRLLAHGEKVGYTIFETPDQRQLMHLGHPE
CCCCCCEECCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCCEEEECCCCHHHHHHCCCCC
YNVDRLKSEMERDKKRGDVPPPENFDLTKSNTSWRSHRNLLFQQWLWFCYQRVSLSV
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]