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The map label for this gene is yfbT [H]

Identifier: 124025386

GI number: 124025386

Start: 623641

End: 624321

Strand: Reverse

Name: yfbT [H]

Synonym: NATL1_06771

Alternate gene names: 124025386

Gene position: 624321-623641 (Counterclockwise)

Preceding gene: 124025388

Following gene: 124025380

Centisome position: 33.48

GC content: 36.56

Gene sequence:

>681_bases
ATGAAGAAAAATTGGAATTTTCCTAAAGCAATTTTATTTGATCTTGATGGAGTTCTCATTGATTCAGAACCCTTACATGG
ACAAGCATGGAAAGAAACCGCCGCACTTTTTGATCTAAATTTAACCCTTGACCAACTAAAACTCTTGAGAGGAAAAAGAA
GAATTGATTGTGCCAATGAACTAGTTAAATTGATTCCAAAGACAGTTGAGGCGAAAGACTTACTAGACCGTCATAGACCC
ATTTCAAGACAACTCATCCTTAGGGCCCAAGCAATGCAAGGTGGAGAGAGCTTAGTAGAAAGGTGTCATAAGAACAATAT
CCCAATGGCTTTAGTAACTAGTAGCAGCGCGGAATCATTCCAAATAAAAACGACTCAACACAAATGGATGAATCTATTTT
CTGTGATAGTTCTTGGCGATGAAAAATTACTAGCGAAGGGGAAACCAGCTCCAGATCCATATCTACTAGCAGCTAAAAAA
TTAAATATTGCTCCTCAAGAATGCTGGGCTGTTGAAGATTCAATTGCTGGAGCATCTTCAGCCTTAGAGGCTGGATGTTG
TGTTTTATTTTTAAAAGCACAAAGTGAAGAACTTCCGAAAAAAGAAGATTTGGATCAACACATTAATTTAAGACAAATCA
GTCATCTAAAAGAAATTGATCAAATATTGAATGAGTACTAA

Upstream 100 bases:

>100_bases
GAATTCATGAAAGATAAAAACAACTTTTCATTTATTTCATTCAAGCTATTTCTGACCAAAAGGCTTGAATAGTGAAACTC
TTATTTAAAACAAATTCATA

Downstream 100 bases:

>100_bases
GTTAATAAAGTCTGCTAATAACAAATTCAGGTAATTCTAGTAAAGCTGTTTTTGATGGTGAATCTGGCAACCAAGAAATA
GAATCTTTTGATTCAGATGC

Product: phosphatase/phosphohexomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKKNWNFPKAILFDLDGVLIDSEPLHGQAWKETAALFDLNLTLDQLKLLRGKRRIDCANELVKLIPKTVEAKDLLDRHRP
ISRQLILRAQAMQGGESLVERCHKNNIPMALVTSSSAESFQIKTTQHKWMNLFSVIVLGDEKLLAKGKPAPDPYLLAAKK
LNIAPQECWAVEDSIAGASSALEAGCCVLFLKAQSEELPKKEDLDQHINLRQISHLKEIDQILNEY

Sequences:

>Translated_226_residues
MKKNWNFPKAILFDLDGVLIDSEPLHGQAWKETAALFDLNLTLDQLKLLRGKRRIDCANELVKLIPKTVEAKDLLDRHRP
ISRQLILRAQAMQGGESLVERCHKNNIPMALVTSSSAESFQIKTTQHKWMNLFSVIVLGDEKLLAKGKPAPDPYLLAAKK
LNIAPQECWAVEDSIAGASSALEAGCCVLFLKAQSEELPKKEDLDQHINLRQISHLKEIDQILNEY
>Mature_226_residues
MKKNWNFPKAILFDLDGVLIDSEPLHGQAWKETAALFDLNLTLDQLKLLRGKRRIDCANELVKLIPKTVEAKDLLDRHRP
ISRQLILRAQAMQGGESLVERCHKNNIPMALVTSSSAESFQIKTTQHKWMNLFSVIVLGDEKLLAKGKPAPDPYLLAAKK
LNIAPQECWAVEDSIAGASSALEAGCCVLFLKAQSEELPKKEDLDQHINLRQISHLKEIDQILNEY

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrate glucose 6-phosphate [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=184, Percent_Identity=33.1521739130435, Blast_Score=111, Evalue=4e-25,
Organism=Homo sapiens, GI296011028, Length=156, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI207113149, Length=207, Percent_Identity=29.4685990338164, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI296011030, Length=184, Percent_Identity=29.8913043478261, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI87082080, Length=223, Percent_Identity=32.7354260089686, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789046, Length=176, Percent_Identity=25.5681818181818, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554716, Length=192, Percent_Identity=32.8125, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI116008157, Length=184, Percent_Identity=29.3478260869565, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI17137324, Length=184, Percent_Identity=30.4347826086957, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45550911, Length=178, Percent_Identity=29.2134831460674, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20129151, Length=187, Percent_Identity=28.3422459893048, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 25442; Mature: 25442

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNWNFPKAILFDLDGVLIDSEPLHGQAWKETAALFDLNLTLDQLKLLRGKRRIDCANE
CCCCCCCCCEEEEECCCEEECCCCCCCHHHHHHHHHEEECCCHHHHHHHHCCCCCCHHHH
LVKLIPKTVEAKDLLDRHRPISRQLILRAQAMQGGESLVERCHKNNIPMALVTSSSAESF
HHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCE
QIKTTQHKWMNLFSVIVLGDEKLLAKGKPAPDPYLLAAKKLNIAPQECWAVEDSIAGASS
EEECHHHHHHHHHHHEEECCHHHHHCCCCCCCCEEEEHHHCCCCHHHHHHHHHHHCCCHH
ALEAGCCVLFLKAQSEELPKKEDLDQHINLRQISHLKEIDQILNEY
HHHCCEEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKNWNFPKAILFDLDGVLIDSEPLHGQAWKETAALFDLNLTLDQLKLLRGKRRIDCANE
CCCCCCCCCEEEEECCCEEECCCCCCCHHHHHHHHHEEECCCHHHHHHHHCCCCCCHHHH
LVKLIPKTVEAKDLLDRHRPISRQLILRAQAMQGGESLVERCHKNNIPMALVTSSSAESF
HHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCE
QIKTTQHKWMNLFSVIVLGDEKLLAKGKPAPDPYLLAAKKLNIAPQECWAVEDSIAGASS
EEECHHHHHHHHHHHEEECCHHHHHCCCCCCCCEEEEHHHCCCCHHHHHHHHHHHCCCHH
ALEAGCCVLFLKAQSEELPKKEDLDQHINLRQISHLKEIDQILNEY
HHHCCEEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 10493123 [H]