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The map label for this gene is tdcF [C]

Identifier: 124025324

GI number: 124025324

Start: 556964

End: 557371

Strand: Reverse

Name: tdcF [C]

Synonym: NATL1_06131

Alternate gene names: 124025324

Gene position: 557371-556964 (Counterclockwise)

Preceding gene: 124025325

Following gene: 124025323

Centisome position: 29.89

GC content: 36.76

Gene sequence:

>408_bases
ATGAAAAGTTCATCGATTGAGGCCATAGAAACAAAATTTGCGCCTAAGCCCGTTGGTCCCTACAACCAAGCTATTTTGGT
TGAAAACTACTTATATTGCTCAGGACAAATTGCTTTAGACCCTTCAACTGGTGTAATGGTCGGGAATGGAAATATAGAAG
AAGAAACTAGACAAGTTCTAAAAAATTTAATGGCTGTAGTTGAAGCCGCTGGAGGAAGAAGTTCAGCTGTAATAAGAACA
ACCATCTACTTAACGGATTTAAATGATTTCGCAAAAGTAAATGAAATTTATGCAGAAACTTTCAACAAAACAGTAAGTCC
CGCAAGAGCATGCGTTGAAGTATCAAAGCTTCCTAAAGGAGGAAAGATTGAGATAGATTGCATAGCTTGGTTAGAAAACA
AAAAGTAA

Upstream 100 bases:

>100_bases
AAATGTCGAGAAATTTACAATGCTAAGGAAACACAAAGATAGATGGAAATGTTAAATTCTAATTTGTGTATCAAATCTAT
TCATTAAAGTCTAATCATTC

Downstream 100 bases:

>100_bases
AAAAACAACATTATGACTAAATCGAGCCTTGCCACTTTGCTAAGTGGCCCCATTATTGACTAAGTTAATTATTGATTAGC
AATACACAATGTCCACTGCC

Product: YjgF family translation initiation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MKSSSIEAIETKFAPKPVGPYNQAILVENYLYCSGQIALDPSTGVMVGNGNIEEETRQVLKNLMAVVEAAGGRSSAVIRT
TIYLTDLNDFAKVNEIYAETFNKTVSPARACVEVSKLPKGGKIEIDCIAWLENKK

Sequences:

>Translated_135_residues
MKSSSIEAIETKFAPKPVGPYNQAILVENYLYCSGQIALDPSTGVMVGNGNIEEETRQVLKNLMAVVEAAGGRSSAVIRT
TIYLTDLNDFAKVNEIYAETFNKTVSPARACVEVSKLPKGGKIEIDCIAWLENKK
>Mature_135_residues
MKSSSIEAIETKFAPKPVGPYNQAILVENYLYCSGQIALDPSTGVMVGNGNIEEETRQVLKNLMAVVEAAGGRSSAVIRT
TIYLTDLNDFAKVNEIYAETFNKTVSPARACVEVSKLPKGGKIEIDCIAWLENKK

Specific function: Unknown

COG id: COG0251

COG function: function code J; Putative translation initiation inhibitor, yjgF family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RutC family [H]

Homologues:

Organism=Homo sapiens, GI5032215, Length=129, Percent_Identity=47.2868217054264, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI87082396, Length=123, Percent_Identity=43.9024390243902, Blast_Score=103, Evalue=3e-24,
Organism=Escherichia coli, GI87082213, Length=123, Percent_Identity=40.650406504065, Blast_Score=102, Evalue=7e-24,
Organism=Escherichia coli, GI1787245, Length=115, Percent_Identity=33.0434782608696, Blast_Score=73, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71982075, Length=121, Percent_Identity=44.6280991735537, Blast_Score=106, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25148896, Length=121, Percent_Identity=44.6280991735537, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71982068, Length=121, Percent_Identity=44.6280991735537, Blast_Score=105, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6322138, Length=130, Percent_Identity=31.5384615384615, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320899, Length=103, Percent_Identity=38.8349514563107, Blast_Score=79, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19921376, Length=122, Percent_Identity=45.9016393442623, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013813
- InterPro:   IPR006175
- InterPro:   IPR006056
- InterPro:   IPR019897 [H]

Pfam domain/function: PF01042 Ribonuc_L-PSP [H]

EC number: NA

Molecular weight: Translated: 14686; Mature: 14686

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS01094 UPF0076

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSSIEAIETKFAPKPVGPYNQAILVENYLYCSGQIALDPSTGVMVGNGNIEEETRQVL
CCCCCCHHHHHCCCCCCCCCCCCEEEEEEEEEECCEEEECCCCCEEEECCCCCHHHHHHH
KNLMAVVEAAGGRSSAVIRTTIYLTDLNDFAKVNEIYAETFNKTVSPARACVEVSKLPKG
HHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
GKIEIDCIAWLENKK
CCEEEEEEEEECCCC
>Mature Secondary Structure
MKSSSIEAIETKFAPKPVGPYNQAILVENYLYCSGQIALDPSTGVMVGNGNIEEETRQVL
CCCCCCHHHHHCCCCCCCCCCCCEEEEEEEEEECCEEEECCCCCEEEECCCCCHHHHHHH
KNLMAVVEAAGGRSSAVIRTTIYLTDLNDFAKVNEIYAETFNKTVSPARACVEVSKLPKG
HHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
GKIEIDCIAWLENKK
CCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7787182; 8590279; 8905231 [H]